Title : Contribution of amino acids in the active site of dipeptidyl peptidase 4 to the catalytic action of the enzyme - Gnoth_2024_PLoS.One_19_e0289239 |
Author(s) : Gnoth K , Bar JW , Rosche F , Rahfeld JU , Demuth HU |
Ref : PLoS ONE , 19 :e0289239 , 2024 |
Abstract : |
PubMedSearch : Gnoth_2024_PLoS.One_19_e0289239 |
PubMedID: 38625918 |
Gene_locus related to this paper: human-DPP4 |
Title : Selective inhibition of dipeptidyl peptidase 4 by targeting a substrate-specific secondary binding site - Kuhn-Wache_2011_Biol.Chem_392_223 |
Author(s) : Kuhn-Wache K , Bar JW , Hoffmann T , Wolf R , Rahfeld JU , Demuth HU |
Ref : Biol Chem , 392 :223 , 2011 |
Abstract : |
PubMedSearch : Kuhn-Wache_2011_Biol.Chem_392_223 |
PubMedID: 21284559 |
Title : Highlight: dipeptidyl peptidase 4 and related proteins - |
Author(s) : Hoffmann T , Demuth HU |
Ref : Biol Chem , 392 :151 , 2011 |
PubMedID: 21291349 |
Title : Distinct glutaminyl cyclase expression in Edinger-Westphal nucleus, locus coeruleus and nucleus basalis Meynert contributes to pGlu-Abeta pathology in Alzheimer's disease - Morawski_2010_Acta.Neuropathol_120_195 |
Author(s) : Morawski M , Hartlage-Rubsamen M , Jager C , Waniek A , Schilling S , Schwab C , McGeer PL , Arendt T , Demuth HU , Rossner S |
Ref : Acta Neuropathologica , 120 :195 , 2010 |
Abstract : |
PubMedSearch : Morawski_2010_Acta.Neuropathol_120_195 |
PubMedID: 20383514 |
Title : Phenotyping of congenic dipeptidyl peptidase 4 (DP4) deficient Dark Agouti (DA) rats suggests involvement of DP4 in neuro-, endocrine, and immune functions - Frerker_2009_Clin.Chem.Lab.Med_47_275 |
Author(s) : Frerker N , Raber K , Bode F , Skripuletz T , Nave H , Klemann C , Pabst R , Stephan M , Schade J , Brabant G , Wedekind D , Jacobs R , Jorns A , Forssmann U , Straub RH , Johannes S , Hoffmann T , Wagner L , Demuth HU , von Horsten S |
Ref : Clinical Chemistry & Laboratory Medicine , 47 :275 , 2009 |
Abstract : |
PubMedSearch : Frerker_2009_Clin.Chem.Lab.Med_47_275 |
PubMedID: 19327106 |
Title : Novel inhibitor for prolyl tripeptidyl aminopeptidase from Porphyromonas gingivalis and details of substrate-recognition mechanism - Xu_2008_J.Mol.Biol_375_708 |
Author(s) : Xu Y , Nakajima Y , Ito K , Zheng H , Oyama H , Heiser U , Hoffmann T , Gartner UT , Demuth HU , Yoshimoto T |
Ref : Journal of Molecular Biology , 375 :708 , 2008 |
Abstract : |
PubMedSearch : Xu_2008_J.Mol.Biol_375_708 |
PubMedID: 18042490 |
Gene_locus related to this paper: porgi-q7muw6 |
Title : Efficacy of the dipeptidyl peptidase IV inhibitor isoleucine thiazolidide (P32\/98) in fatty Zucker rats with incipient and manifest impaired glucose tolerance - Augstein_2008_Diabetes.Obes.Metab_10_850 |
Author(s) : Augstein P , Berg S , Heinke P , Altmann S , Salzsieder E , Demuth HU , Freyse EJ |
Ref : Diabetes Obes Metab , 10 :850 , 2008 |
Abstract : |
PubMedSearch : Augstein_2008_Diabetes.Obes.Metab_10_850 |
PubMedID: 17970756 |
Title : Inhibiting dipeptidyl peptidase activity partially ameliorates colitis in mice - Yazbeck_2008_Front.Biosci_13_6850 |
Author(s) : Yazbeck R , Howarth GS , Geier MS , Demuth HU , Abbott CA |
Ref : Front Biosci , 13 :6850 , 2008 |
Abstract : |
PubMedSearch : Yazbeck_2008_Front.Biosci_13_6850 |
PubMedID: 18508699 |
Title : Regulation of expression and function of dipeptidyl peptidase 4 (DP4), DP8\/9, and DP10 in allergic responses of the lung in rats - Schade_2008_J.Histochem.Cytochem_56_147 |
Author(s) : Schade J , Stephan M , Schmiedl A , Wagner L , Niestroj AJ , Demuth HU , Frerker N , Klemann C , Raber KA , Pabst R , von Horsten S |
Ref : Journal of Histochemistry & Cytochemistry , 56 :147 , 2008 |
Abstract : |
PubMedSearch : Schade_2008_J.Histochem.Cytochem_56_147 |
PubMedID: 17967935 |
Title : Neuropeptide Y (NPY) cleaving enzymes: structural and functional homologues of dipeptidyl peptidase 4 - Frerker_2007_Peptides_28_257 |
Author(s) : Frerker N , Wagner L , Wolf R , Heiser U , Hoffmann T , Rahfeld JU , Schade J , Karl T , Naim HY , Alfalah M , Demuth HU , von Horsten S |
Ref : Peptides , 28 :257 , 2007 |
Abstract : |
PubMedSearch : Frerker_2007_Peptides_28_257 |
PubMedID: 17223229 |
Title : Applications of dipeptidyl peptidase IV inhibitors in diabetes mellitus - McIntosh_2006_Int.J.Biochem.Cell.Biol_38_860 |
Author(s) : McIntosh CH , Demuth HU , Kim SJ , Pospisilik JA , Pederson RA |
Ref : International Journal of Biochemistryistry & Cell Biology , 38 :860 , 2006 |
Abstract : |
PubMedSearch : McIntosh_2006_Int.J.Biochem.Cell.Biol_38_860 |
PubMedID: 16442340 |
Title : Rigidity and flexibility of dipeptidyl peptidase IV: crystal structures of and docking experiments with DPIV - Engel_2006_J.Mol.Biol_355_768 |
Author(s) : Engel M , Hoffmann T , Manhart S , Heiser U , Chambre S , Huber R , Demuth HU , Bode W |
Ref : Journal of Molecular Biology , 355 :768 , 2006 |
Abstract : |
PubMedSearch : Engel_2006_J.Mol.Biol_355_768 |
PubMedID: 16330047 |
Gene_locus related to this paper: pig-dpp4 |
Title : Dipeptidyl peptidase IV: a molecular switch of vascular actions of neuropeptide Y - |
Author(s) : Li L , Demuth HU , Zukowska Z |
Ref : Advances in Experimental Medicine & Biology , 575 :135 , 2006 |
PubMedID: 16700516 |
Title : Distribution of dipeptidyl peptidase IV-like activity enzymes in canine and porcine tissue sections by RT-PCR - |
Author(s) : Wagner L , Hoffmann T , Rahfeld JU , Demuth HU |
Ref : Advances in Experimental Medicine & Biology , 575 :109 , 2006 |
PubMedID: 16700514 |
Title : Type 2 diabetes--therapy with dipeptidyl peptidase IV inhibitors - Demuth_2005_Biochim.Biophys.Acta_1751_33 |
Author(s) : Demuth HU , McIntosh CH , Pederson RA |
Ref : Biochimica & Biophysica Acta , 1751 :33 , 2005 |
Abstract : |
PubMedSearch : Demuth_2005_Biochim.Biophys.Acta_1751_33 |
PubMedID: 15978877 |
Title : Subcellular localization suggests novel functions for prolyl endopeptidase in protein secretion - Schulz_2005_J.Neurochem_94_970 |
Author(s) : Schulz I , Zeitschel U , Rudolph T , Ruiz-Carrillo D , Rahfeld JU , Gerhartz B , Bigl V , Demuth HU , Rossner S |
Ref : Journal of Neurochemistry , 94 :970 , 2005 |
Abstract : |
PubMedSearch : Schulz_2005_J.Neurochem_94_970 |
PubMedID: 16092940 |
Title : Dipeptidyl peptidase IV inhibitors: how do they work as new antidiabetic agents? - McIntosh_2005_Regul.Pept_128_159 |
Author(s) : McIntosh CH , Demuth HU , Pospisilik JA , Pederson R |
Ref : Regul Pept , 128 :159 , 2005 |
Abstract : |
PubMedSearch : McIntosh_2005_Regul.Pept_128_159 |
PubMedID: 15780435 |
Title : Role of dipeptidyl peptidase IV in regulating activity of Na+\/H+ exchanger isoform NHE3 in proximal tubule cells - Girardi_2004_Am.J.Physiol.Cell.Physiol_287_C1238 |
Author(s) : Girardi AC , Knauf F , Demuth HU , Aronson PS |
Ref : American Journal of Physiology Cell Physiol , 287 :C1238 , 2004 |
Abstract : |
PubMedSearch : Girardi_2004_Am.J.Physiol.Cell.Physiol_287_C1238 |
PubMedID: 15213057 |
Title : The crystal structure of dipeptidyl peptidase IV (CD26) reveals its functional regulation and enzymatic mechanism - Engel_2003_Proc.Natl.Acad.Sci.U.S.A_100_5063 |
Author(s) : Engel M , Hoffmann T , Wagner L , Wermann M , Heiser U , Kiefersauer R , Huber R , Bode W , Demuth HU , Brandstetter H |
Ref : Proc Natl Acad Sci U S A , 100 :5063 , 2003 |
Abstract : |
PubMedSearch : Engel_2003_Proc.Natl.Acad.Sci.U.S.A_100_5063 |
PubMedID: 12690074 |
Gene_locus related to this paper: pig-dpp4 |
Title : Characterisation of human dipeptidyl peptidase IV expressed in Pichia pastoris. A structural and mechanistic comparison between the recombinant human and the purified porcine enzyme - Bar_2003_Biol.Chem_384_1553 |
Author(s) : Bar J , Weber A , Hoffmann T , Stork J , Wermann M , Wagner L , Aust S , Gerhartz B , Demuth HU |
Ref : Biol Chem , 384 :1553 , 2003 |
Abstract : |
PubMedSearch : Bar_2003_Biol.Chem_384_1553 |
PubMedID: 14719797 |
Title : Dipeptidyl peptidase IV in the immune system. Effects of specific enzyme inhibitors on activity of dipeptidyl peptidase IV and proliferation of human lymphocytes - Schon_1991_Biol.Chem.Hoppe.Seyler_372_305 |
Author(s) : Schon E , Born I , Demuth HU , Faust J , Neubert K , Steinmetzer T , Barth A , Ansorge S |
Ref : Biol Chem Hoppe Seyler , 372 :305 , 1991 |
Abstract : |
PubMedSearch : Schon_1991_Biol.Chem.Hoppe.Seyler_372_305 |
PubMedID: 1678607 |
Title : Contamination of highly purified human serum cholinesterase by dipeptidyl peptidase IV causing hydrolysis of substance P - Kaemmer_1986_Pharmazie_41_494 |
Author(s) : Kaemmer D , Neubert K , Demuth HU , Barth A |
Ref : Pharmazie , 41 :494 , 1986 |
Abstract : |
PubMedSearch : Kaemmer_1986_Pharmazie_41_494 |
PubMedID: 2430307 |