Title : Dual-Acting Cholinesterase-Human Cannabinoid Receptor 2 Ligands Show Pronounced Neuroprotection in Vitro and Overadditive and Disease-Modifying Neuroprotective Effects in Vivo - Scheiner_2019_J.Med.Chem_62_9078 |
Author(s) : Scheiner M , Dolles D , Gunesch S , Hoffmann M , Nabissi M , Marinelli O , Naldi M , Bartolini M , Petralla S , Poeta E , Monti B , Falkeis C , Vieth M , Hubner H , Gmeiner P , Maitra R , Maurice T , Decker M |
Ref : Journal of Medicinal Chemistry , 62 :9078 , 2019 |
Abstract : |
PubMedSearch : Scheiner_2019_J.Med.Chem_62_9078 |
PubMedID: 31609608 |
Title : Structure-Activity Relationships and Computational Investigations into the Development of Potent and Balanced Dual-Acting Butyrylcholinesterase Inhibitors and Human Cannabinoid Receptor 2 Ligands with Pro-Cognitive in Vivo Profiles - Dolles_2018_J.Med.Chem_61_1646 |
Author(s) : Dolles D , Hoffmann M , Gunesch S , Marinelli O , Moller J , Santoni G , Chatonnet A , Lohse MJ , Wittmann HJ , Strasser A , Nabissi M , Maurice T , Decker M |
Ref : Journal of Medicinal Chemistry , 61 :1646 , 2018 |
Abstract : |
PubMedSearch : Dolles_2018_J.Med.Chem_61_1646 |
PubMedID: 29400965 |
Title : Aminobenzimidazoles and Structural Isomers as Templates for Dual-Acting Butyrylcholinesterase Inhibitors and hCB2 R Ligands To Combat Neurodegenerative Disorders - Dolles_2016_ChemMedChem_11_1270 |
Author(s) : Dolles D , Nimczick M , Scheiner M , Ramler J , Stadtmuller P , Sawatzky E , Drakopoulos A , Sotriffer C , Wittmann HJ , Strasser A , Decker M |
Ref : ChemMedChem , 11 :1270 , 2016 |
Abstract : |
PubMedSearch : Dolles_2016_ChemMedChem_11_1270 |
PubMedID: 26548365 |