| Title : Quinolinetrione-tacrine hybrids as multi-target-directed ligands against Alzheimer's disease - Uliassi_2023_Bioorg.Med.Chem_91_117419 |
| Author(s) : Uliassi E , Bergamini C , Rizzardi N , Naldi M , Cores A , Bartolini M , Carlos Menendez J , Bolognesi ML |
| Ref : Bioorganic & Medicinal Chemistry , 91 :117419 , 2023 |
| Abstract : |
| PubMedSearch : Uliassi_2023_Bioorg.Med.Chem_91_117419 |
| PubMedID: 37487339 |
| Title : Discovery and In Vivo Proof of Concept of a Highly Potent Dual Inhibitor of Soluble Epoxide Hydrolase and Acetylcholinesterase for the Treatment of Alzheimer's Disease - Codony_2022_J.Med.Chem_65_4909 |
| Author(s) : Codony S , Pont C , Grinan-Ferre C , Di Pede-Mattatelli A , Calvo-Tusell C , Feixas F , Osuna S , Jarne-Ferrer J , Naldi M , Bartolini M , Loza MI , Brea J , Perez B , Bartra C , Sanfeliu C , Juarez-Jimenez J , Morisseau C , Hammock BD , Pallas M , Vazquez S , Munoz-Torrero D |
| Ref : Journal of Medicinal Chemistry , 65 :4909 , 2022 |
| Abstract : |
| PubMedSearch : Codony_2022_J.Med.Chem_65_4909 |
| PubMedID: 35271276 |
| Title : Discovery of sustainable drugs for Alzheimer's disease: cardanol-derived cholinesterase inhibitors with antioxidant and anti-amyloid properties - de Andrade Ramos_2021_RSC.Med.Chem_12_1154 |
| Author(s) : de Andrade Ramos G , Souza de Oliveira A , Bartolini M , Naldi M , Liparulo I , Bergamini C , Uliassi E , Wu L , Fraser PE , Abreu M , Kiametis AS , Gargano R , Silveira ER , Brand GD , Prchal L , Soukup O , Korabecny J , Bolognesi ML , Soares Romeiro LA |
| Ref : RSC Med Chem , 12 :1154 , 2021 |
| Abstract : |
| PubMedSearch : de Andrade Ramos_2021_RSC.Med.Chem_12_1154 |
| PubMedID: 34355181 |
| Title : From virtual screening hits targeting a cryptic pocket in BACE-1 to a nontoxic brain permeable multitarget anti-Alzheimer lead with disease-modifying and cognition-enhancing effects - Pont_2021_Eur.J.Med.Chem_225_113779 |
| Author(s) : Pont C , Ginex T , Grinan-Ferre C , Scheiner M , Mattellone A , Martinez N , Arce EM , Soriano-Fernandez Y , Naldi M , De Simone A , Barenys M , Gomez-Catalan J , Perez B , Sabate R , Andrisano V , Loza MI , Brea J , Bartolini M , Bolognesi ML , Decker M , Pallas M , Luque FJ , Munoz-Torrero D |
| Ref : Eur Journal of Medicinal Chemistry , 225 :113779 , 2021 |
| Abstract : |
| PubMedSearch : Pont_2021_Eur.J.Med.Chem_225_113779 |
| PubMedID: 34418785 |
| Title : Bio-Guided Fractionation of Stem Bark Extracts from Phyllanthus muellarianus: Identification of Phytocomponents with Anti-Cholinesterase Activity - Naldi_2021_Molecules_26_ |
| Author(s) : Naldi M , Brusotti G , Massolini G , Andrisano V , Temporini C , Bartolini M |
| Ref : Molecules , 26 : , 2021 |
| Abstract : |
| PubMedSearch : Naldi_2021_Molecules_26_ |
| PubMedID: 34299650 |
| Title : New Coumarin Derivatives as Cholinergic and Cannabinoid System Modulators - Montanari_2021_Molecules_26_3254 |
| Author(s) : Montanari S , Allara M , Scalvini L , Kostrzewa M , Belluti F , Gobbi S , Naldi M , Rivara S , Bartolini M , Ligresti A , Bisi A , Rampa A |
| Ref : Molecules , 26 :3254 , 2021 |
| Abstract : |
| PubMedSearch : Montanari_2021_Molecules_26_3254 |
| PubMedID: 34071439 |
| Title : Functional characterization of multifunctional ligands targeting acetylcholinesterase and alpha 7 nicotinic acetylcholine receptor - Cieslikiewicz-Bouet_2020_Biochem.Pharmacol__114010 |
| Author(s) : Cieslikiewicz-Bouet M , Naldi M , Bartolini M , Perez B , Servent D , Jean L , Araoz R , Renard PY |
| Ref : Biochemical Pharmacology , :114010 , 2020 |
| Abstract : |
| PubMedSearch : Cieslikiewicz-Bouet_2020_Biochem.Pharmacol__114010 |
| PubMedID: 32360492 |
| Title : Design, biological evaluation and X-ray crystallography of nanomolar multifunctional ligands targeting simultaneously acetylcholinesterase and glycogen synthase kinase-3 - Oukoloff_2019_Eur.J.Med.Chem_168_58 |
| Author(s) : Oukoloff K , Coquelle N , Bartolini M , Naldi M , Le Guevel R , Bach S , Josselin B , Ruchaud S , Catto M , Pisani L , Denora N , Iacobazzi RM , Silman I , Sussman JL , Buron F , Colletier JP , Jean L , Routier S , Renard PY |
| Ref : Eur Journal of Medicinal Chemistry , 168 :58 , 2019 |
| Abstract : |
| PubMedSearch : Oukoloff_2019_Eur.J.Med.Chem_168_58 |
| PubMedID: 30798053 |
| Gene_locus related to this paper: torca-ACHE |
| Title : Advanced analytical methodologies in Alzheimer's disease drug discovery - De Simone_2019_J.Pharm.Biomed.Anal_178_112899 |
| Author(s) : De Simone A , Naldi M , Tedesco D , Bartolini M , Davani L , Andrisano V |
| Ref : J Pharm Biomed Anal , 178 :112899 , 2019 |
| Abstract : |
| PubMedSearch : De Simone_2019_J.Pharm.Biomed.Anal_178_112899 |
| PubMedID: 31606562 |
| Title : Discovery of novel benzofuran-based compounds with neuroprotective and immunomodulatory properties for Alzheimer's disease treatment - Montanari_2019_Eur.J.Med.Chem_178_243 |
| Author(s) : Montanari S , Mahmoud AM , Pruccoli L , Rabbito A , Naldi M , Petralla S , Moraleda I , Bartolini M , Monti B , Iriepa I , Belluti F , Gobbi S , Di Marzo V , Bisi A , Tarozzi A , Ligresti A , Rampa A |
| Ref : Eur Journal of Medicinal Chemistry , 178 :243 , 2019 |
| Abstract : |
| PubMedSearch : Montanari_2019_Eur.J.Med.Chem_178_243 |
| PubMedID: 31185414 |
| Title : Dual-Acting Cholinesterase-Human Cannabinoid Receptor 2 Ligands Show Pronounced Neuroprotection in Vitro and Overadditive and Disease-Modifying Neuroprotective Effects in Vivo - Scheiner_2019_J.Med.Chem_62_9078 |
| Author(s) : Scheiner M , Dolles D , Gunesch S , Hoffmann M , Nabissi M , Marinelli O , Naldi M , Bartolini M , Petralla S , Poeta E , Monti B , Falkeis C , Vieth M , Hubner H , Gmeiner P , Maitra R , Maurice T , Decker M |
| Ref : Journal of Medicinal Chemistry , 62 :9078 , 2019 |
| Abstract : |
| PubMedSearch : Scheiner_2019_J.Med.Chem_62_9078 |
| PubMedID: 31609608 |
| Title : A patent review of butyrylcholinesterase inhibitors and reactivators 2010-2017 - Andrisano_2018_Expert.Opin.Ther.Pat_28_455 |
| Author(s) : Andrisano V , Naldi M , De Simone A , Bartolini M |
| Ref : Expert Opin Ther Pat , 28 :455 , 2018 |
| Abstract : |
| PubMedSearch : Andrisano_2018_Expert.Opin.Ther.Pat_28_455 |
| PubMedID: 29757691 |
| Title : Exploiting the Chalcone Scaffold to Develop Multifunctional Agents for Alzheimer's Disease - Rampa_2018_Molecules_23_ |
| Author(s) : Rampa A , Bartolini M , Pruccoli L , Naldi M , Iriepa I , Moraleda I , Belluti F , Gobbi S , Tarozzi A , Bisi A |
| Ref : Molecules , 23 : , 2018 |
| Abstract : |
| PubMedSearch : Rampa_2018_Molecules_23_ |
| PubMedID: 30061534 |
| Title : Fluorescence biosensing micropatterned surfaces based on immobilized human acetylcholinesterase - Bartolini_2013_Anal.Bioanal.Chem_405_795 |
| Author(s) : Bartolini M , Naldi M , Nicolau DV , van Delft FC , van Zijl J , Snijder J , van den Heuvel EF , Naburgh EP , Calonghi N , Andrisano V |
| Ref : Anal Bioanal Chem , 405 :795 , 2013 |
| Abstract : |
| PubMedSearch : Bartolini_2013_Anal.Bioanal.Chem_405_795 |
| PubMedID: 22814970 |
| Title : Multiwell fluorometric and colorimetric microassays for the evaluation of beta-secretase (BACE-1) inhibitors - Mancini_2007_Anal.Bioanal.Chem_388_1175 |
| Author(s) : Mancini F , Naldi M , Cavrini V , Andrisano V |
| Ref : Anal Bioanal Chem , 388 :1175 , 2007 |
| Abstract : |
| PubMedSearch : Mancini_2007_Anal.Bioanal.Chem_388_1175 |
| PubMedID: 17541560 |