| Title : The Covid-19 oral drug Molnupiravir is a CES2 substrate: potential drug-drug interactions and impact of CES2 genetic polymorphism in vitro - Shen_2022_Drug.Metab.Dispos__ |
| Author(s) : Shen Y , Eades W , Liu W , Yan B |
| Ref : Drug Metabolism & Disposition: The Biological Fate of Chemicals , : , 2022 |
| Abstract : |
| PubMedSearch : Shen_2022_Drug.Metab.Dispos__ |
| PubMedID: 35790245 |
| Title : Covalent CES2 Inhibitors Protect against Reduced Formation of Intestinal Organoids by the Anticancer Drug Irinotecan - Eades_2022_Curr.Drug.Metab__ |
| Author(s) : Eades W , Liu W , Shen Y , Shi Z , Yan B |
| Ref : Curr Drug Metab , : , 2022 |
| Abstract : |
| PubMedSearch : Eades_2022_Curr.Drug.Metab__ |
| PubMedID: 36515038 |
| Title : The COVID-19 medicine remdesivir is therapeutically activated by carboxylesterase-1 AND excessive hydrolysis increases cytotoxicity - Shen_2021_Hepatol.Commun__ |
| Author(s) : Shen Y , Eades W , Yan B |
| Ref : Hepatol Commun , : , 2021 |
| Abstract : |
| PubMedSearch : Shen_2021_Hepatol.Commun__ |
| PubMedID: 34230903 |
| Title : Remdesivir potently inhibits carboxylesterase-2 through covalent modifications: signifying strong drug-drug interactions - Shen_2021_Fundam.Clin.Pharmacol_35_432 |
| Author(s) : Shen Y , Eades W , Yan B |
| Ref : Fundamental & Clinical Toxicology , 35 :432 , 2021 |
| Abstract : |
| PubMedSearch : Shen_2021_Fundam.Clin.Pharmacol_35_432 |
| PubMedID: 33369768 |
| Gene_locus related to this paper: human-CES2 |