Title : Viral target- and metabolism-based rationale for combined use of recently authorized small molecule COVID-19 medicines: molnupiravir, nirmatrelvir and remdesivir - Yan_2023_Fundam.Clin.Pharmacol__ |
Author(s) : Yan D , Yan B |
Ref : Fundamental & Clinical Toxicology , : , 2023 |
Abstract : |
PubMedSearch : Yan_2023_Fundam.Clin.Pharmacol__ |
PubMedID: 36931725 |
Title : Association Lp-PLA2 Gene Polymorphisms with Coronary Heart Disease - Ma_2022_Dis.Markers_2022_9775699 |
Author(s) : Ma S , Ding L , Cai M , Chen L , Yan B , Yang J |
Ref : Dis Markers , 2022 :9775699 , 2022 |
Abstract : |
PubMedSearch : Ma_2022_Dis.Markers_2022_9775699 |
PubMedID: 35818585 |
Gene_locus related to this paper: human-PLA2G7 |
Title : The Covid-19 oral drug Molnupiravir is a CES2 substrate: potential drug-drug interactions and impact of CES2 genetic polymorphism in vitro - Shen_2022_Drug.Metab.Dispos__ |
Author(s) : Shen Y , Eades W , Liu W , Yan B |
Ref : Drug Metabolism & Disposition: The Biological Fate of Chemicals , : , 2022 |
Abstract : |
PubMedSearch : Shen_2022_Drug.Metab.Dispos__ |
PubMedID: 35790245 |
Title : Effect of alcohol exposure on the efficacy and safety of tenofovir alafenamide fumarate, a major medicine against human immunodeficiency virus - Liu_2022_Biochem.Pharmacol_204_115224 |
Author(s) : Liu W , Yu S , Yan B |
Ref : Biochemical Pharmacology , 204 :115224 , 2022 |
Abstract : |
PubMedSearch : Liu_2022_Biochem.Pharmacol_204_115224 |
PubMedID: 36007574 |
Title : Covalent CES2 Inhibitors Protect against Reduced Formation of Intestinal Organoids by the Anticancer Drug Irinotecan - Eades_2022_Curr.Drug.Metab__ |
Author(s) : Eades W , Liu W , Shen Y , Shi Z , Yan B |
Ref : Curr Drug Metab , : , 2022 |
Abstract : |
PubMedSearch : Eades_2022_Curr.Drug.Metab__ |
PubMedID: 36515038 |
Title : Peroxidase-like activity of Ru-N-C nanozymes in colorimetric assay of acetylcholinesterase activity - Yan_2022_Anal.Chim.Acta_1191_339362 |
Author(s) : Yan B , Wang F , He S , Liu W , Zhang C , Chen C , Lu Y |
Ref : Anal Chim Acta , 1191 :339362 , 2022 |
Abstract : |
PubMedSearch : Yan_2022_Anal.Chim.Acta_1191_339362 |
PubMedID: 35033267 |
Title : Pig Liver Esterases Hydrolyze Endocannabinoids and Promote Inflammatory Response - Zhou_2021_Front.Immunol_12_670427 |
Author(s) : Zhou Q , Yan B , Sun W , Chen Q , Xiao Q , Xiao Y , Wang X , Shi D |
Ref : Front Immunol , 12 :670427 , 2021 |
Abstract : |
PubMedSearch : Zhou_2021_Front.Immunol_12_670427 |
PubMedID: 34079552 |
Gene_locus related to this paper: pig-PLE1 , pig-a0a1s6l967 |
Title : The nucleoside antiviral prodrug remdesivir in treating COVID-19 and beyond with interspecies significance - Yan_2021_Anim.Dis_1_15 |
Author(s) : Yan D , Ra OH , Yan B |
Ref : Anim Dis , 1 :15 , 2021 |
Abstract : |
PubMedSearch : Yan_2021_Anim.Dis_1_15 |
PubMedID: 34778881 |
Title : The COVID-19 medicine remdesivir is therapeutically activated by carboxylesterase-1 AND excessive hydrolysis increases cytotoxicity - Shen_2021_Hepatol.Commun__ |
Author(s) : Shen Y , Eades W , Yan B |
Ref : Hepatol Commun , : , 2021 |
Abstract : |
PubMedSearch : Shen_2021_Hepatol.Commun__ |
PubMedID: 34230903 |
Title : Remdesivir potently inhibits carboxylesterase-2 through covalent modifications: signifying strong drug-drug interactions - Shen_2021_Fundam.Clin.Pharmacol_35_432 |
Author(s) : Shen Y , Eades W , Yan B |
Ref : Fundamental & Clinical Toxicology , 35 :432 , 2021 |
Abstract : |
PubMedSearch : Shen_2021_Fundam.Clin.Pharmacol_35_432 |
PubMedID: 33369768 |
Gene_locus related to this paper: human-CES2 |
Title : Comprehensive Interrogation on Acetylcholinesterase Inhibition by Ionic Liquids Using Machine Learning and Molecular Modeling - Yan_2021_Environ.Sci.Technol__ |
Author(s) : Yan J , Yan X , Hu S , Zhu H , Yan B |
Ref : Environ Sci Technol , : , 2021 |
Abstract : |
PubMedSearch : Yan_2021_Environ.Sci.Technol__ |
PubMedID: 34636548 |
Title : Evidence-based complementary and alternative medicine bioinformatics approach through network pharmacology and molecular docking to determine the molecular mechanisms of Erjing pill in Alzheimer's disease - Yang_2021_Exp.Ther.Med_22_1252 |
Author(s) : Yang X , Guan Y , Yan B , Xie Y , Zhou M , Wu Y , Yao L , Qiu X , Yan F , Chen Y , Huang L |
Ref : Exp Ther Med , 22 :1252 , 2021 |
Abstract : |
PubMedSearch : Yang_2021_Exp.Ther.Med_22_1252 |
PubMedID: 34539848 |
Title : Colorimetric detection of acetylcholinesterase and its inhibitor based on thiol-regulated oxidase-like activity of 2D palladium square nanoplates on reduced graphene oxide - Yan_2021_Mikrochim.Acta_188_162 |
Author(s) : Yan B , Liu W , Duan G , Ni P , Jiang Y , Zhang C , Wang B , Lu Y , Chen C |
Ref : Mikrochim Acta , 188 :162 , 2021 |
Abstract : |
PubMedSearch : Yan_2021_Mikrochim.Acta_188_162 |
PubMedID: 33839958 |
Title : Toxicological analysis of roast duck flavor components - Zhou_2018_Food.Chem.Toxicol_119_438 |
Author(s) : Zhou Y , Yan B , Zhao S , Zhou X , Xiao Y |
Ref : Food & Chemical Toxicology , 119 :438 , 2018 |
Abstract : |
PubMedSearch : Zhou_2018_Food.Chem.Toxicol_119_438 |
PubMedID: 29208505 |
Title : Protective effects of tetrahydropalmatine against ketamine-induced learning and memory injury via antioxidative, anti-inflammatory and anti-apoptotic mechanisms in mice - Zhang_2018_Mol.Med.Rep_17_6873 |
Author(s) : Zhang Y , Sha R , Wang K , Li H , Yan B , Zhou N |
Ref : Mol Med Rep , 17 :6873 , 2018 |
Abstract : |
PubMedSearch : Zhang_2018_Mol.Med.Rep_17_6873 |
PubMedID: 29512789 |
Title : ChAT-positive neurons participate in subventricular zone neurogenesis after middle cerebral artery occlusion in mice - Wang_2017_Behav.Brain.Res_316_145 |
Author(s) : Wang J , Fu X , Zhang D , Yu L , Li N , Lu Z , Gao Y , Wang M , Liu X , Zhou C , Han W , Yan B |
Ref : Behavioural Brain Research , 316 :145 , 2017 |
Abstract : |
PubMedSearch : Wang_2017_Behav.Brain.Res_316_145 |
PubMedID: 27609645 |
Title : Competitive Inhibition Mechanism of Acetylcholinesterase without Catalytic Active Site Interaction: Study on Functionalized C60 Nanoparticles via in Vitro and in Silico Assays (correction of zauthor adresses 9_44954) - Liu_2017_ACS.Appl.Mater.Interfaces_9_18626 |
Author(s) : Liu Y , Yan B , Winkler DA , Fu J , Zhang A |
Ref : ACS Appl Mater Interfaces , 9 :18626 , 2017 |
Abstract : |
PubMedSearch : Liu_2017_ACS.Appl.Mater.Interfaces_9_18626 |
PubMedID: 28492309 |
Title : Ontogenic expression of human carboxylesterase-2 and cytochrome P450 3A4 in liver and duodenum: Postnatal surge and organ-dependent regulation - Chen_2015_Toxicology_330_55 |
Author(s) : Chen YT , Trzoss L , Yang D , Yan B |
Ref : Toxicology , 330 :55 , 2015 |
Abstract : |
PubMedSearch : Chen_2015_Toxicology_330_55 |
PubMedID: 25724353 |
Title : Regulation of carboxylesterase-2 expression by p53 family proteins and enhanced anti-cancer activities among 5-fluorouracil, irinotecan and doxazolidine prodrug - Xiao_2013_Br.J.Pharmacol_168_1989 |
Author(s) : Xiao D , Yang D , Guo L , Lu W , Charpentier M , Yan B |
Ref : British Journal of Pharmacology , 168 :1989 , 2013 |
Abstract : |
PubMedSearch : Xiao_2013_Br.J.Pharmacol_168_1989 |
PubMedID: 23373735 |
Title : Modulation of esterified drug metabolism by tanshinones from Salvia miltiorrhiza (Danshen) - Hatfield_2013_J.Nat.Prod_76_36 |
Author(s) : Hatfield MJ , Tsurkan LG , Hyatt JL , Edwards CC , Lemoff A , Jeffries C , Yan B , Potter PM |
Ref : Journal of Natural Products , 76 :36 , 2013 |
Abstract : |
PubMedSearch : Hatfield_2013_J.Nat.Prod_76_36 |
PubMedID: 23286284 |
Title : Carboxylesterase-2 is a highly sensitive target of the antiobesity agent orlistat with profound implications in the activation of anticancer prodrugs - Xiao_2013_Biochem.Pharmacol_85_439 |
Author(s) : Xiao D , Shi D , Yang D , Barthel B , Koch TH , Yan B |
Ref : Biochemical Pharmacology , 85 :439 , 2013 |
Abstract : |
PubMedSearch : Xiao_2013_Biochem.Pharmacol_85_439 |
PubMedID: 23228697 |
Gene_locus related to this paper: human-CES2 |
Title : [Assessment of marine environmental stress based on the integrated biomarker response index model: a case study in west coast of Guangxi] - Xing_2013_Ying.Yong.Sheng.Tai.Xue.Bao_24_3581 |
Author(s) : Xing YZ , Zhou HL , Wu B , Yan B |
Ref : Ying Yong Sheng Tai Xue Bao , 24 :3581 , 2013 |
Abstract : |
PubMedSearch : Xing_2013_Ying.Yong.Sheng.Tai.Xue.Bao_24_3581 |
PubMedID: 24697082 |
Title : Antioxidant sulforaphane and sensitizer trinitrobenzene sulfonate induce carboxylesterase-1 through a novel element transactivated by nuclear factor-E2 related factor-2 - Chen_2012_Biochem.Pharmacol_84_864 |
Author(s) : Chen YT , Shi D , Yang D , Yan B |
Ref : Biochemical Pharmacology , 84 :864 , 2012 |
Abstract : |
PubMedSearch : Chen_2012_Biochem.Pharmacol_84_864 |
PubMedID: 22776248 |
Title : Lipopolysaccharide down-regulates carbolesterases 1 and 2 and reduces hydrolysis activity in vitro and in vivo via p38MAPK-NF-kappaB pathway - Mao_2011_Toxicol.Lett_201_213 |
Author(s) : Mao Z , Li Y , Peng Y , Luan X , Gui H , Feng X , Hu G , Shen J , Yan B , Yang J |
Ref : Toxicol Lett , 201 :213 , 2011 |
Abstract : |
PubMedSearch : Mao_2011_Toxicol.Lett_201_213 |
PubMedID: 21237253 |
Title : Requirements for mammalian carboxylesterase inhibition by substituted ethane-1,2-diones - Parkinson_2011_Bioorg.Med.Chem_19_4635 |
Author(s) : Parkinson EI , Hatfield MJ , Tsurkan L , Hyatt JL , Edwards CC , Hicks LD , Yan B , Potter PM |
Ref : Bioorganic & Medicinal Chemistry , 19 :4635 , 2011 |
Abstract : |
PubMedSearch : Parkinson_2011_Bioorg.Med.Chem_19_4635 |
PubMedID: 21733699 |
Title : Surge in expression of carboxylesterase 1 during the post-neonatal stage enables a rapid gain of the capacity to activate the anti-influenza prodrug oseltamivir - Shi_2011_J.Infect.Dis_203_937 |
Author(s) : Shi D , Yang D , Prinssen EP , Davies BE , Yan B |
Ref : J Infect Dis , 203 :937 , 2011 |
Abstract : |
PubMedSearch : Shi_2011_J.Infect.Dis_203_937 |
PubMedID: 21402544 |
Title : Recommended nomenclature for five mammalian carboxylesterase gene families: human, mouse, and rat genes and proteins - Holmes_2010_Mamm.Genome_21_427 |
Author(s) : Holmes RS , Wright MW , Laulederkind SJ , Cox LA , Hosokawa M , Imai T , Ishibashi S , Lehner R , Miyazaki M , Perkins EJ , Potter PM , Redinbo MR , Robert J , Satoh T , Yamashita T , Yan B , Yokoi T , Zechner R , Maltais LJ |
Ref : Mamm Genome , 21 :427 , 2010 |
Abstract : |
PubMedSearch : Holmes_2010_Mamm.Genome_21_427 |
PubMedID: 20931200 |
Gene_locus related to this paper: human-CES1 , human-CES2 , human-CES3 , human-CES4A , human-CES5A |
Title : Human carboxylesterases HCE1 and HCE2: ontogenic expression, inter-individual variability and differential hydrolysis of oseltamivir, aspirin, deltamethrin and permethrin - Yang_2009_Biochem.Pharmacol_77_238 |
Author(s) : Yang D , Pearce RE , Wang X , Gaedigk R , Wan YJ , Yan B |
Ref : Biochemical Pharmacology , 77 :238 , 2009 |
Abstract : |
PubMedSearch : Yang_2009_Biochem.Pharmacol_77_238 |
PubMedID: 18983829 |
Gene_locus related to this paper: human-CES1 , human-CES2 |
Title : Pyrethroid insecticides: isoform-dependent hydrolysis, induction of cytochrome P450 3A4 and evidence on the involvement of the pregnane X receptor - Yang_2009_Toxicol.Appl.Pharmacol_237_49 |
Author(s) : Yang D , Wang X , Chen YT , Deng R , Yan B |
Ref : Toxicol Appl Pharmacol , 237 :49 , 2009 |
Abstract : |
PubMedSearch : Yang_2009_Toxicol.Appl.Pharmacol_237_49 |
PubMedID: 19249324 |
Title : Photochemotherapeutic agent 8-methoxypsoralen induces cytochrome P450 3A4 and carboxylesterase HCE2: evidence on an involvement of the pregnane X receptor - Yang_2007_Toxicol.Sci_95_13 |
Author(s) : Yang J , Yan B |
Ref : Toxicol Sci , 95 :13 , 2007 |
Abstract : |
PubMedSearch : Yang_2007_Toxicol.Sci_95_13 |
PubMedID: 17003103 |
Title : Interleukin-6 alters the cellular responsiveness to clopidogrel, irinotecan, and oseltamivir by suppressing the expression of carboxylesterases HCE1 and HCE2 - Yang_2007_Mol.Pharmacol_72_686 |
Author(s) : Yang J , Shi D , Yang D , Song X , Yan B |
Ref : Molecular Pharmacology , 72 :686 , 2007 |
Abstract : |
PubMedSearch : Yang_2007_Mol.Pharmacol_72_686 |
PubMedID: 17537833 |
Gene_locus related to this paper: human-CES1 , human-CES2 |
Title : Anti-influenza prodrug oseltamivir is activated by carboxylesterase human carboxylesterase 1, and the activation is inhibited by antiplatelet agent clopidogrel - Shi_2006_J.Pharmacol.Exp.Ther_319_1477 |
Author(s) : Shi D , Yang J , Yang D , LeCluyse EL , Black C , You L , Akhlaghi F , Yan B |
Ref : Journal of Pharmacology & Experimental Therapeutics , 319 :1477 , 2006 |
Abstract : |
PubMedSearch : Shi_2006_J.Pharmacol.Exp.Ther_319_1477 |
PubMedID: 16966469 |
Title : Antiplatelet agents aspirin and clopidogrel are hydrolyzed by distinct carboxylesterases, and clopidogrel is transesterificated in the presence of ethyl alcohol - Tang_2006_J.Pharmacol.Exp.Ther_319_1467 |
Author(s) : Tang M , Mukundan M , Yang J , Charpentier N , LeCluyse EL , Black C , Yang D , Shi D , Yan B |
Ref : Journal of Pharmacology & Experimental Therapeutics , 319 :1467 , 2006 |
Abstract : |
PubMedSearch : Tang_2006_J.Pharmacol.Exp.Ther_319_1467 |
PubMedID: 16943252 |
Gene_locus related to this paper: human-CES1 |
Title : Comparative carboxylesterase activities in infant and adult liver and their in vitro sensitivity to chlorpyrifos oxon - Pope_2005_Regul.Toxicol.Pharmacol_42_64 |
Author(s) : Pope CN , Karanth S , Liu J , Yan B |
Ref : Regul Toxicol Pharmacol , 42 :64 , 2005 |
Abstract : |
PubMedSearch : Pope_2005_Regul.Toxicol.Pharmacol_42_64 |
PubMedID: 15896444 |
Title : Intramolecular disulfide bonds are required for folding hydrolase B into a catalytically active conformation but not for maintaining it during catalysis - Song_2004_Biochem.Biophys.Res.Commun_319_1072 |
Author(s) : Song X , Gragen S , Li Y , Ma Y , Liu J , Yang D , Matoney L , Yan B |
Ref : Biochemical & Biophysical Research Communications , 319 :1072 , 2004 |
Abstract : |
PubMedSearch : Song_2004_Biochem.Biophys.Res.Commun_319_1072 |
PubMedID: 15194477 |
Title : Irinotecan activation by human carboxylesterases in colorectal adenocarcinoma cells - Wu_2002_Clin.Cancer.Res_8_2696 |
Author(s) : Wu MH , Yan B , Humerickhouse R , Dolan ME |
Ref : Clin Cancer Research , 8 :2696 , 2002 |
Abstract : |
PubMedSearch : Wu_2002_Clin.Cancer.Res_8_2696 |
PubMedID: 12171903 |
Title : Human and rodent carboxylesterases: immunorelatedness, overlapping substrate specificity, differential sensitivity to serine enzyme inhibitors, and tumor-related expression - Xie_2002_Drug.Metab.Dispos_30_541 |
Author(s) : Xie M , Yang D , Liu L , Xue B , Yan B |
Ref : Drug Metabolism & Disposition: The Biological Fate of Chemicals , 30 :541 , 2002 |
Abstract : |
PubMedSearch : Xie_2002_Drug.Metab.Dispos_30_541 |
PubMedID: 11950785 |
Title : Effects of washout and dose-escalation periods on the efficacy, safety, and tolerability of galantamine in patients previously treated with donepezil: ongoing clinical trials - Rasmusen_2001_Clin.Ther_23 Suppl A_A25 |
Author(s) : Rasmusen L , Yan B , Robillard A , Dunbar F |
Ref : Clin Ther , 23 Suppl A :A25 , 2001 |
Abstract : |
PubMedSearch : Rasmusen_2001_Clin.Ther_23 Suppl A_A25 |
PubMedID: 11396868 |
Title : Human carboxylesterases in term placentae: enzymatic characterization, molecular cloning and evidence for the existence of multiple forms - Yan_1999_Placenta_20_599 |
Author(s) : Yan B , Matoney L , Yang D |
Ref : Placenta , 20 :599 , 1999 |
Abstract : |
PubMedSearch : Yan_1999_Placenta_20_599 |
PubMedID: 10452915 |
Title : Rat serum carboxylesterase. Cloning, expression, regulation, and evidence of secretion from liver - Yan_1995_J.Biol.Chem_270_19128 |
Author(s) : Yan B , Yang D , Bullock P , Parkinson A |
Ref : Journal of Biological Chemistry , 270 :19128 , 1995 |
Abstract : |
PubMedSearch : Yan_1995_J.Biol.Chem_270_19128 |
PubMedID: 7642579 |
Gene_locus related to this paper: human-CES1 |
Title : Cloning and expression of hydrolase C, a member of the rat carboxylesterase family - Yan_1995_Arch.Biochem.Biophys_317_222 |
Author(s) : Yan B , Yang D , Parkinson A |
Ref : Archives of Biochemistry & Biophysics , 317 :222 , 1995 |
Abstract : |
PubMedSearch : Yan_1995_Arch.Biochem.Biophys_317_222 |
PubMedID: 7872788 |
Gene_locus related to this paper: ratno-lmcxe |
Title : Rat kidney carboxylesterase. Cloning, sequencing, cellular localization, and relationship to rat liver hydrolase - Yan_1994_J.Biol.Chem_269_29688 |
Author(s) : Yan B , Yang D , Brady M , Parkinson A |
Ref : Journal of Biological Chemistry , 269 :29688 , 1994 |
Abstract : |
PubMedSearch : Yan_1994_J.Biol.Chem_269_29688 |
PubMedID: 7961958 |
Gene_locus related to this paper: ratno-kmcxe , ratno-lmcxe |
Title : Purification and characterization of two rat liver microsomal carboxylesterases (hydrolase A and B) - Morgan_1994_Arch.Biochem.Biophys_315_495 |
Author(s) : Morgan EW , Yan B , Greenway D , Petersen DR , Parkinson A |
Ref : Archives of Biochemistry & Biophysics , 315 :495 , 1994 |
Abstract : |
PubMedSearch : Morgan_1994_Arch.Biochem.Biophys_315_495 |
PubMedID: 7986098 |
Gene_locus related to this paper: ratno-kmcxe , ratno-q68g49 |