| Title : In Vitro-In Vivo Extrapolation of Intestinal Availability for Carboxylesterase Substrates Using Portal Vein-Cannulated Monkey - Trapa_2017_J.Pharm.Sci_106_898 |
| Author(s) : Trapa PE , Beaumont K , Atkinson K , Eng H , King-Ahmad A , Scott DO , Maurer TS , Di L |
| Ref : J Pharm Sci , 106 :898 , 2017 |
| Abstract : |
| PubMedSearch : Trapa_2017_J.Pharm.Sci_106_898 |
| PubMedID: 27998705 |
| Title : Liver-Targeted Small-Molecule Inhibitors of Proprotein Convertase Subtilisin\/Kexin Type 9 Synthesis - McClure_2017_Angew.Chem.Int.Ed.Engl_56_16218 |
| Author(s) : McClure KF , Piotrowski DW , Petersen D , Wei L , Xiao J , Londregan AT , Kamlet AS , Dechert-Schmitt AM , Raymer B , Ruggeri RB , Canterbury D , Limberakis C , Liras S , DaSilva-Jardine P , Dullea RG , Loria PM , Reidich B , Salatto CT , Eng H , Kimoto E , Atkinson K , King-Ahmad A , Scott D , Beaumont K , Chabot JR , Bolt MW , Maresca K , Dahl K , Arakawa R , Takano A , Halldin C |
| Ref : Angew Chem Int Ed Engl , 56 :16218 , 2017 |
| Abstract : |
| PubMedSearch : McClure_2017_Angew.Chem.Int.Ed.Engl_56_16218 |
| PubMedID: 29073340 |
| Title : Undesired versus designed enzymatic cleavage of linkers for liver targeting - Chirapu_2014_Bioorg.Med.Chem.Lett_24_1144 |
| Author(s) : Chirapu SR , Bauman JN , Eng H , Goosen TC , Strelevitz TJ , Sinha SC , Dow RL , Finn MG |
| Ref : Bioorganic & Medicinal Chemistry Lett , 24 :1144 , 2014 |
| Abstract : |
| PubMedSearch : Chirapu_2014_Bioorg.Med.Chem.Lett_24_1144 |
| PubMedID: 24461291 |
| Title : Utility of the carboxylesterase inhibitor bis-para-nitrophenylphosphate (BNPP) in the plasma unbound fraction determination for a hydrolytically unstable amide derivative and agonist of the TGR5 receptor - Eng_2010_Xenobiotica_40_369 |
| Author(s) : Eng H , Niosi M , McDonald TS , Wolford A , Chen Y , Simila ST , Bauman JN , Warmus J , Kalgutkar AS |
| Ref : Xenobiotica , 40 :369 , 2010 |
| Abstract : |
| PubMedSearch : Eng_2010_Xenobiotica_40_369 |
| PubMedID: 20297923 |