Ruggeri RB

Title : Liver-Targeted Small-Molecule Inhibitors of Proprotein Convertase Subtilisin\/Kexin Type 9 Synthesis - McClure_2017_Angew.Chem.Int.Ed.Engl_56_16218

Author(s) : McClure KF , Piotrowski DW , Petersen D , Wei L , Xiao J , Londregan AT , Kamlet AS , Dechert-Schmitt AM , Raymer B , Ruggeri RB , Canterbury D , Limberakis C , Liras S , DaSilva-Jardine P , Dullea RG , Loria PM , Reidich B , Salatto CT , Eng H , Kimoto E , Atkinson K , King-Ahmad A , Scott D , Beaumont K , Chabot JR , Bolt MW , Maresca K , Dahl K , Arakawa R , Takano A , Halldin C

Ref : Angew Chem Int Ed Engl , 56 :16218 , 2017

Abstract :

PubMedSearch : McClure_2017_Angew.Chem.Int.Ed.Engl_56_16218

PubMedID: 29073340

Title : Insights into the Novel Hydrolytic Mechanism of a Diethyl 2-Phenyl-2-(2-arylacetoxy)methyl Malonate Ester-Based Microsomal Triglyceride Transfer Protein (MTP) Inhibitor - Ryder_2012_Chem.Res.Toxicol_25_2138

Author(s) : Ryder T , Walker GS , Goosen TC , Ruggeri RB , Conn EL , Rocke BN , Lapham K , Steppan CM , Hepworth D , Kalgutkar AS

Ref : Chemical Research in Toxicology , 25 :2138 , 2012

Abstract :

PubMedSearch : Ryder_2012_Chem.Res.Toxicol_25_2138

PubMedID: 22989032

Ruggeri RB

References (2)

1. Liver-Targeted Small-Molecule Inhibitors of Proprotein Convertase Subtilisin\/Kexin Type 9 Synthesis - McClure_2017_Angew.Chem.Int.Ed.Engl_56_16218

2. Insights into the Novel Hydrolytic Mechanism of a Diethyl 2-Phenyl-2-(2-arylacetoxy)methyl Malonate Ester-Based Microsomal Triglyceride Transfer Protein (MTP) Inhibitor - Ryder_2012_Chem.Res.Toxicol_25_2138