| Title : Discovery of Potent Cholinesterase Inhibition-Based Multi-Target-Directed Lead Compounds for Synaptoprotection in Alzheimer's Disease - Turgutalp_2022_J.Med.Chem__ |
| Author(s) : Turgutalp B , Bhattarai P , Ercetin T , Luise C , Reis R , Gurdal EE , Isaak A , Biriken D , Dinter E , Sipahi H , Schepmann D , Junker A , Wunsch B , Sippl W , Gulcan HO , Kizil C , Yarim M |
| Ref : Journal of Medicinal Chemistry , : , 2022 |
| Abstract : |
| PubMedSearch : Turgutalp_2022_J.Med.Chem__ |
| PubMedID: 36084304 |
| Title : The hybrid compounds as multi-target ligands for the treatment of Alzheimer's Disease: Considerations on Donepezil - Gulcan_2021_Curr.Top.Med.Chem__ |
| Author(s) : Gulcan HO , Kosar M |
| Ref : Curr Top Med Chem , : , 2021 |
| Abstract : |
| PubMedSearch : Gulcan_2021_Curr.Top.Med.Chem__ |
| PubMedID: 34766890 |
| Title : Dual monoamine oxidase and cholinesterase Inhibitors with different heterocyclic scaffolds - Gulcan_2021_Curr.Top.Med.Chem_21_2752 |
| Author(s) : Gulcan HO , Orhan IE |
| Ref : Curr Top Med Chem , 21 :2752 , 2021 |
| Abstract : |
| PubMedSearch : Gulcan_2021_Curr.Top.Med.Chem_21_2752 |
| PubMedID: 34477521 |
| Title : Design, synthesis, and biological evaluation of new urolithin amides as multitarget agents against Alzheimer's disease - Shukur_2021_Arch.Pharm.(Weinheim)__e2000467 |
| Author(s) : Shukur KT , Ercetin T , Luise C , Sippl W , Sirkecioglu O , Ulgen M , Coskun GP , Yarim M , Gazi M , Gulcan HO |
| Ref : Arch Pharm (Weinheim) , :e2000467 , 2021 |
| Abstract : |
| PubMedSearch : Shukur_2021_Arch.Pharm.(Weinheim)__e2000467 |
| PubMedID: 33511649 |
| Title : The main targets involved in neuroprotection for the treatment of Alzheimer's Disease and Parkinson Disease - Gulcan_2020_Curr.Pharm.Des__ |
| Author(s) : Gulcan HO , Orhan IE |
| Ref : Curr Pharm Des , : , 2020 |
| Abstract : |
| PubMedSearch : Gulcan_2020_Curr.Pharm.Des__ |
| PubMedID: 32003681 |
| Title : Design, synthesis and biological evaluation of new benzoxazolone\/benzothiazolone derivatives as multi-target agents against Alzheimer's disease - Erdogan_2020_Eur.J.Med.Chem_212_113124 |
| Author(s) : Erdogan M , Kilic B , Sagkan RI , Aksakal F , Ercetin T , Gulcan HO , Dogruer DS |
| Ref : Eur Journal of Medicinal Chemistry , 212 :113124 , 2020 |
| Abstract : |
| PubMedSearch : Erdogan_2020_Eur.J.Med.Chem_212_113124 |
| PubMedID: 33395623 |
| Title : A Recent Look into Natural Products that Have Potential to Inhibit Cholinesterases and Monoamine Oxidase B: Update on 2010-2019 - Gulcan_2020_Comb.Chem.High.Throughput.Screen__ |
| Author(s) : Gulcan HO , Orhan IE |
| Ref : Comb Chem High Throughput Screen , : , 2020 |
| Abstract : |
| PubMedSearch : Gulcan_2020_Comb.Chem.High.Throughput.Screen__ |
| PubMedID: 31985374 |
| Title : Synthesis, Characterization, Molecular Docking, and Biological Activities of Some Natural and Synthetic Urolithin Analogs - Noshadi_2020_Chem.Biodivers_17_e2000197 |
| Author(s) : Noshadi B , Ercetin T , Luise C , Yuksel MY , Sippl W , Sahin MF , Gazi M , Gulcan HO |
| Ref : Chem Biodivers , 17 :e2000197 , 2020 |
| Abstract : |
| PubMedSearch : Noshadi_2020_Chem.Biodivers_17_e2000197 |
| PubMedID: 32497364 |
| Title : Design, Synthesis and Investigation of New Diphenyl Substituted Pyridazinone Derivatives as Both Cholinesterase and Abeta-Aggregation Inhibitors - Kilic_2019_Med.Chem_15_59 |
| Author(s) : Kilic B , Erdogan M , Gulcan HO , Aksakal F , Oruklu N , Bagriacik EU , Dogruer DS |
| Ref : Med Chem , 15 :59 , 2019 |
| Abstract : |
| PubMedSearch : Kilic_2019_Med.Chem_15_59 |
| PubMedID: 29792155 |
| Title : Design and synthesis of some new carboxamide and propanamide derivatives bearing phenylpyridazine as a core ring and the investigation of their inhibitory potential on in-vitro acetylcholinesterase and butyrylcholinesterase - Kilic_2018_Bioorg.Chem_79_235 |
| Author(s) : Kilic B , Gulcan HO , Aksakal F , Ercetin T , Oruklu N , Umit Bagriacik E , Dogruer DS |
| Ref : Bioorg Chem , 79 :235 , 2018 |
| Abstract : |
| PubMedSearch : Kilic_2018_Bioorg.Chem_79_235 |
| PubMedID: 29775949 |
| Title : Synthesis of Novel Benzothiazole-Piperazine Derivatives and Their Biological Evaluation as Acetylcholinesterase Inhibitors and Cytotoxic Agents - Gurdal_2017_Anticancer.Agents.Med.Chem_17_1837 |
| Author(s) : Gurdal EE , Turgutalp B , Gulcan HO , Ercetin T , Sahin MF , Durmaz I , Atalay RC , Nguyen QD , Sippl W , Yarim M |
| Ref : Anticancer Agents Med Chem , 17 :1837 , 2017 |
| Abstract : |
| PubMedSearch : Gurdal_2017_Anticancer.Agents.Med.Chem_17_1837 |
| PubMedID: 28403780 |
| Title : Chemical and molecular aspects on interactions of galanthamine and its derivatives with cholinesterases - Gulcan_2015_Curr.Pharm.Biotechnol_16_252 |
| Author(s) : Gulcan HO , Orhan IE , Sener B |
| Ref : Curr Pharm Biotechnol , 16 :252 , 2015 |
| Abstract : |
| PubMedSearch : Gulcan_2015_Curr.Pharm.Biotechnol_16_252 |
| PubMedID: 25483718 |
| Title : Coumarins: Auspicious Cholinesterase and Monoamine Oxidase Inhibitors - Orhan_2015_Curr.Top.Med.Chem_15_1673 |
| Author(s) : Orhan IE , Gulcan HO |
| Ref : Curr Top Med Chem , 15 :1673 , 2015 |
| Abstract : |
| PubMedSearch : Orhan_2015_Curr.Top.Med.Chem_15_1673 |
| PubMedID: 25915613 |
| Title : Design, synthesis and biological evaluation of novel 6H-benzo[c]chromen-6-one, and 7,8,9,10-tetrahydro-benzo[c]chromen-6-one derivatives as potential cholinesterase inhibitors - Gulcan_2014_Bioorg.Med.Chem_22_5141 |
| Author(s) : Gulcan HO , Unlu S , Esiringu I , Ercetin T , Sahin Y , Oz D , Sahin MF |
| Ref : Bioorganic & Medicinal Chemistry , 22 :5141 , 2014 |
| Abstract : |
| PubMedSearch : Gulcan_2014_Bioorg.Med.Chem_22_5141 |
| PubMedID: 25189690 |