| Title : Discovery of Potent Cholinesterase Inhibition-Based Multi-Target-Directed Lead Compounds for Synaptoprotection in Alzheimer's Disease - Turgutalp_2022_J.Med.Chem__ |
| Author(s) : Turgutalp B , Bhattarai P , Ercetin T , Luise C , Reis R , Gurdal EE , Isaak A , Biriken D , Dinter E , Sipahi H , Schepmann D , Junker A , Wunsch B , Sippl W , Gulcan HO , Kizil C , Yarim M |
| Ref : Journal of Medicinal Chemistry , : , 2022 |
| Abstract : |
| PubMedSearch : Turgutalp_2022_J.Med.Chem__ |
| PubMedID: 36084304 |
| Title : Design, synthesis, and biological evaluation of new urolithin amides as multitarget agents against Alzheimer's disease - Shukur_2021_Arch.Pharm.(Weinheim)__e2000467 |
| Author(s) : Shukur KT , Ercetin T , Luise C , Sippl W , Sirkecioglu O , Ulgen M , Coskun GP , Yarim M , Gazi M , Gulcan HO |
| Ref : Arch Pharm (Weinheim) , :e2000467 , 2021 |
| Abstract : |
| PubMedSearch : Shukur_2021_Arch.Pharm.(Weinheim)__e2000467 |
| PubMedID: 33511649 |
| Title : Synthesis, Characterization, Molecular Docking, and Biological Activities of Some Natural and Synthetic Urolithin Analogs - Noshadi_2020_Chem.Biodivers_17_e2000197 |
| Author(s) : Noshadi B , Ercetin T , Luise C , Yuksel MY , Sippl W , Sahin MF , Gazi M , Gulcan HO |
| Ref : Chem Biodivers , 17 :e2000197 , 2020 |
| Abstract : |
| PubMedSearch : Noshadi_2020_Chem.Biodivers_17_e2000197 |
| PubMedID: 32497364 |
| Title : Synthesis and Biological Investigation of Phenothiazine-Based Benzhydroxamic Acids as Selective Histone Deacetylase 6 Inhibitors - Vogerl_2019_J.Med.Chem_62_1138 |
| Author(s) : Vogerl K , Ong N , Senger J , Herp D , Schmidtkunz K , Marek M , Muller M , Bartel K , Shaik TB , Porter NJ , Robaa D , Christianson DW , Romier C , Sippl W , Jung M , Bracher F |
| Ref : Journal of Medicinal Chemistry , 62 :1138 , 2019 |
| Abstract : |
| PubMedSearch : Vogerl_2019_J.Med.Chem_62_1138 |
| PubMedID: 30645113 |
| Title : Ursolic and oleanolic acid derivatives with cholinesterase inhibiting potential - Loesche_2018_Bioorg.Chem_85_23 |
| Author(s) : Loesche A , Kowitsch A , Lucas SD , Al-Halabi Z , Sippl W , Al-Harrasi A , Csuk R |
| Ref : Bioorg Chem , 85 :23 , 2018 |
| Abstract : |
| PubMedSearch : Loesche_2018_Bioorg.Chem_85_23 |
| PubMedID: 30599410 |
| Title : Unexpected AChE inhibitory activity of (2E)alpha,beta-unsaturated fatty acids - Loesche_2018_Bioorg.Med.Chem.Lett_28_3315 |
| Author(s) : Loesche A , Wiemann J , Al Halabi Z , Karasch J , Sippl W , Csuk R |
| Ref : Bioorganic & Medicinal Chemistry Lett , 28 :3315 , 2018 |
| Abstract : |
| PubMedSearch : Loesche_2018_Bioorg.Med.Chem.Lett_28_3315 |
| PubMedID: 30220607 |
| Title : Synthesis of Novel Benzothiazole-Piperazine Derivatives and Their Biological Evaluation as Acetylcholinesterase Inhibitors and Cytotoxic Agents - Gurdal_2017_Anticancer.Agents.Med.Chem_17_1837 |
| Author(s) : Gurdal EE , Turgutalp B , Gulcan HO , Ercetin T , Sahin MF , Durmaz I , Atalay RC , Nguyen QD , Sippl W , Yarim M |
| Ref : Anticancer Agents Med Chem , 17 :1837 , 2017 |
| Abstract : |
| PubMedSearch : Gurdal_2017_Anticancer.Agents.Med.Chem_17_1837 |
| PubMedID: 28403780 |
| Title : Design, synthesis, and structure-activity relationships of a series of 3-[2-(1-benzylpiperidin-4-yl)ethylamino]pyridazine derivatives as acetylcholinesterase inhibitors - Contreras_2001_J.Med.Chem_44_2707 |
| Author(s) : Contreras JM , Parrot I , Sippl W , Rival YM , Wermuth CG |
| Ref : Journal of Medicinal Chemistry , 44 :2707 , 2001 |
| Abstract : |
| PubMedSearch : Contreras_2001_J.Med.Chem_44_2707 |
| PubMedID: 11495583 |
| Title : Structure-based 3D QSAR and design of novel acetylcholinesterase inhibitors - Sippl_2001_J.Comput.Aided.Mol.Des_15_395 |
| Author(s) : Sippl W , Contreras JM , Parrot I , Rival YM , Wermuth CG |
| Ref : J Comput Aided Mol Des , 15 :395 , 2001 |
| Abstract : |
| PubMedSearch : Sippl_2001_J.Comput.Aided.Mol.Des_15_395 |
| PubMedID: 11394735 |