| Title : 2-{N-[-(1-Benzylpiperidin-4-yl)alkyl]amino}-6-[(prop-2-yn-1-yl)amino]pyridine-3,5-dicarbonitriles Showing High Affinity for (1\/2) Receptors - Deuther-Conrad_2025_Int.J.Mol.Sci_26_ |
| Author(s) : Deuther-Conrad W , Schepmann D , Iriepa I , Lopez-Munoz F , Chioua M , Wunsch B , Samadi A , Marco-Contelles J |
| Ref : Int J Mol Sci , 26 : , 2025 |
| Abstract : |
| PubMedSearch : Deuther-Conrad_2025_Int.J.Mol.Sci_26_ |
| PubMedID: 39941036 |
| Title : Discovery of Potent Cholinesterase Inhibition-Based Multi-Target-Directed Lead Compounds for Synaptoprotection in Alzheimer's Disease - Turgutalp_2022_J.Med.Chem__ |
| Author(s) : Turgutalp B , Bhattarai P , Ercetin T , Luise C , Reis R , Gurdal EE , Isaak A , Biriken D , Dinter E , Sipahi H , Schepmann D , Junker A , Wunsch B , Sippl W , Gulcan HO , Kizil C , Yarim M |
| Ref : Journal of Medicinal Chemistry , : , 2022 |
| Abstract : |
| PubMedSearch : Turgutalp_2022_J.Med.Chem__ |
| PubMedID: 36084304 |
| Title : Setup and Validation of a Reliable Docking Protocol for the Development of Neuroprotective Agents by Targeting the Sigma-1 Receptor (S1R) - Rossino_2020_Int.J.Mol.Sci_21_ |
| Author(s) : Rossino G , Rui M , Pozzetti L , Schepmann D , Wunsch B , Zampieri D , Pellavio G , Laforenza U , Rinaldi S , Colombo G , Morelli L , Linciano P , Rossi D , Collina S |
| Ref : Int J Mol Sci , 21 : , 2020 |
| Abstract : |
| PubMedSearch : Rossino_2020_Int.J.Mol.Sci_21_ |
| PubMedID: 33081037 |
| Title : Identification of dual Sigma1 receptor modulators\/acetylcholinesterase inhibitors with antioxidant and neurotrophic properties, as neuroprotective agents - Rui_2018_Eur.J.Med.Chem_158_353 |
| Author(s) : Rui M , Rossino G , Coniglio S , Monteleone S , Scuteri A , Malacrida A , Rossi D , Catenacci L , Sorrenti M , Paolillo M , Curti D , Venturini L , Schepmann D , Wunsch B , Liedl KR , Cavaletti G , Pace V , Urban E , Collina S |
| Ref : Eur Journal of Medicinal Chemistry , 158 :353 , 2018 |
| Abstract : |
| PubMedSearch : Rui_2018_Eur.J.Med.Chem_158_353 |
| PubMedID: 30223122 |
| Title : Lipase-catalyzed kinetic resolution as key step in the synthesis of enantiomerically pure sigma ligands with 2-benzopyran structure - Knappmann_2017_Bioorg.Med.Chem_25_3384 |
| Author(s) : Knappmann I , Lehmkuhl K , Kohler J , Schepmann D , Giera M , Bracher F , Wunsch B |
| Ref : Bioorganic & Medicinal Chemistry , 25 :3384 , 2017 |
| Abstract : |
| PubMedSearch : Knappmann_2017_Bioorg.Med.Chem_25_3384 |
| PubMedID: 28501431 |
| Gene_locus related to this paper: burce-lipaa |
| Title : Bivalent beta-carbolines as potential multitarget anti-Alzheimer agents - Rook_2010_J.Med.Chem_53_3611 |
| Author(s) : Rook Y , Schmidtke KU , Gaube F , Schepmann D , Wunsch B , Heilmann J , Lehmann J , Winckler T |
| Ref : Journal of Medicinal Chemistry , 53 :3611 , 2010 |
| Abstract : |
| PubMedSearch : Rook_2010_J.Med.Chem_53_3611 |
| PubMedID: 20361801 |
| Title : The allosteric modulation of lipases and its possible biological relevance - Kohler_2007_Theor.Biol.Med.Model_4_34 |
| Author(s) : Kohler J , Wunsch B |
| Ref : Theor Biol Med Model , 4 :34 , 2007 |
| Abstract : |
| PubMedSearch : Kohler_2007_Theor.Biol.Med.Model_4_34 |
| PubMedID: 17825093 |