Title : Discovery of 3-methyl-N-(1-oxy-3',4',5',6'-tetrahydro-2'H-[2,4'-bipyridine]-1'-ylmethyl)benzam ide (ABT-670), an orally bioavailable dopamine D4 agonist for the treatment of erectile dysfunction - Patel_2006_J.Med.Chem_49_7450 |
Author(s) : Patel MV , Kolasa T , Mortell K , Matulenko MA , Hakeem AA , Rohde JJ , Nelson SL , Cowart MD , Nakane M , Miller LN , Uchic ME , Terranova MA , El-Kouhen OF , Donnelly-Roberts D , Namovic MT , Hollingsworth PR , Chang R , Martino BR , Wetter JM , Marsh KC , Martin R , Darbyshire JF , Gintant G , Hsieh GC , Moreland RB , Sullivan JP , Brioni JD , Stewart AO |
Ref : Journal of Medicinal Chemistry , 49 :7450 , 2006 |
Abstract : |
PubMedSearch : Patel_2006_J.Med.Chem_49_7450 |
PubMedID: 17149874 |
Title : 1-aryl-3-(4-pyridine-2-ylpiperazin-1-yl)propan-1-one oximes as potent dopamine D4 receptor agonists for the treatment of erectile dysfunction - Kolasa_2006_J.Med.Chem_49_5093 |
Author(s) : Kolasa T , Matulenko MA , Hakeem AA , Patel MV , Mortell K , Bhatia P , Henry R , Nakane M , Hsieh GC , Terranova MA , Uchic ME , Miller LN , Chang R , Donnelly-Roberts D , Namovic MT , Hollingsworth PR , Martino B , El Kouhen O , Marsh KC , Wetter JM , Moreland RB , Brioni JD , Stewart AO |
Ref : Journal of Medicinal Chemistry , 49 :5093 , 2006 |
Abstract : |
PubMedSearch : Kolasa_2006_J.Med.Chem_49_5093 |
PubMedID: 16913699 |
Title : Synthesis and functional activity of (2-aryl-1-piperazinyl)-N-(3-methylphenyl)acetamides: selective dopamine D4 receptor agonists - Matulenko_2004_Bioorg.Med.Chem_12_3471 |
Author(s) : Matulenko MA , Hakeem AA , Kolasa T , Nakane M , Terranova MA , Uchic ME , Miller LN , Chang R , Donnelly-Roberts D , Namovic MT , Moreland RB , Brioni JD , Stewart AO |
Ref : Bioorganic & Medicinal Chemistry , 12 :3471 , 2004 |
Abstract : |
PubMedSearch : Matulenko_2004_Bioorg.Med.Chem_12_3471 |
PubMedID: 15186832 |