Brioni JD

References (20)

Title : Fatty acid amide hydrolase inhibitors display broad selectivity and inhibit multiple carboxylesterases as off-targets - Zhang_2007_Neuropharmacol_52_1095
Author(s) : Zhang D , Saraf A , Kolasa T , Bhatia P , Zheng GZ , Patel M , Lannoye GS , Richardson P , Stewart A , Rogers JC , Brioni JD , Surowy CS
Ref : Neuropharmacology , 52 :1095 , 2007
PubMedID: 17217969

Title : Discovery of 3-methyl-N-(1-oxy-3',4',5',6'-tetrahydro-2'H-[2,4'-bipyridine]-1'-ylmethyl)benzam ide (ABT-670), an orally bioavailable dopamine D4 agonist for the treatment of erectile dysfunction - Patel_2006_J.Med.Chem_49_7450
Author(s) : Patel MV , Kolasa T , Mortell K , Matulenko MA , Hakeem AA , Rohde JJ , Nelson SL , Cowart MD , Nakane M , Miller LN , Uchic ME , Terranova MA , El-Kouhen OF , Donnelly-Roberts D , Namovic MT , Hollingsworth PR , Chang R , Martino BR , Wetter JM , Marsh KC , Martin R , Darbyshire JF , Gintant G , Hsieh GC , Moreland RB , Sullivan JP , Brioni JD , Stewart AO
Ref : Journal of Medicinal Chemistry , 49 :7450 , 2006
PubMedID: 17149874

Title : 1-aryl-3-(4-pyridine-2-ylpiperazin-1-yl)propan-1-one oximes as potent dopamine D4 receptor agonists for the treatment of erectile dysfunction - Kolasa_2006_J.Med.Chem_49_5093
Author(s) : Kolasa T , Matulenko MA , Hakeem AA , Patel MV , Mortell K , Bhatia P , Henry R , Nakane M , Hsieh GC , Terranova MA , Uchic ME , Miller LN , Chang R , Donnelly-Roberts D , Namovic MT , Hollingsworth PR , Martino B , El Kouhen O , Marsh KC , Wetter JM , Moreland RB , Brioni JD , Stewart AO
Ref : Journal of Medicinal Chemistry , 49 :5093 , 2006
PubMedID: 16913699

Title : 2-[4-(3,4-Dimethylphenyl)piperazin-1-ylmethyl]-1H benzoimidazole (A-381393), a selective dopamine D4 receptor antagonist - Nakane_2005_Neuropharmacol_49_112
Author(s) : Nakane M , Cowart MD , Hsieh GC , Miller L , Uchic ME , Chang R , Terranova MA , Donnelly-Roberts D , Namovic MT , Miller TR , Wetter JM , Marsh K , Stewart AO , Brioni JD , Moreland RB
Ref : Neuropharmacology , 49 :112 , 2005
PubMedID: 15992586

Title : Activation of dopamine D4 receptors by ABT-724 induces penile erection in rats - Brioni_2004_Proc.Natl.Acad.Sci.U.S.A_101_6758
Author(s) : Brioni JD , Moreland RB , Cowart M , Hsieh GC , Stewart AO , Hedlund P , Donnelly-Roberts D , Nakane M , Lynch JJ, 3rd , Kolasa T , Polakowski JS , Osinski MA , Marsh K , Andersson KE , Sullivan JP
Ref : Proc Natl Acad Sci U S A , 101 :6758 , 2004
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Title : Synthesis and functional activity of (2-aryl-1-piperazinyl)-N-(3-methylphenyl)acetamides: selective dopamine D4 receptor agonists - Matulenko_2004_Bioorg.Med.Chem_12_3471
Author(s) : Matulenko MA , Hakeem AA , Kolasa T , Nakane M , Terranova MA , Uchic ME , Miller LN , Chang R , Donnelly-Roberts D , Namovic MT , Moreland RB , Brioni JD , Stewart AO
Ref : Bioorganic & Medicinal Chemistry , 12 :3471 , 2004
PubMedID: 15186832

Title : Discovery of 2-(4-pyridin-2-ylpiperazin-1-ylmethyl)-1H-benzimidazole (ABT-724), a dopaminergic agent with a novel mode of action for the potential treatment of erectile dysfunction - Cowart_2004_J.Med.Chem_47_3853
Author(s) : Cowart M , Latshaw SP , Bhatia P , Daanen JF , Rohde J , Nelson SL , Patel M , Kolasa T , Nakane M , Uchic ME , Miller LN , Terranova MA , Chang R , Donnelly-Roberts D , Namovic MT , Hollingsworth PR , Martino BR , Lynch JJ, 3rd , Sullivan JP , Hsieh GC , Moreland RB , Brioni JD , Stewart AO
Ref : Journal of Medicinal Chemistry , 47 :3853 , 2004
PubMedID: 15239663

Title : Synthesis and activity of 2-[4-(4-[3H]-2-cyanophenyl)piperazinyl]-N-(2,4,6-[3H]3-3-methylphenyl)acetamide: a selective dopamine D4 receptor agonist and radioligand - Matulenko_2004_Bioorg.Med.Chem.Lett_14_5095
Author(s) : Matulenko MA , Surber B , Fan L , Kolasa T , Nakane M , Terranova MA , Uchic ME , Miller LN , Chang R , Donnelly-Roberts D , Namovic MT , Moreland RB , Brioni JD , Stewart AO
Ref : Bioorganic & Medicinal Chemistry Lett , 14 :5095 , 2004
PubMedID: 15380206

Title : Comparative pharmacology of human dopamine D(2)-like receptor stable cell lines coupled to calcium flux through Galpha(qo5) - Moreland_2004_Biochem.Pharmacol_68_761
Author(s) : Moreland RB , Nakane M , Donnelly-Roberts D , Miller LN , Chang R , Uchic ME , Terranova MA , Gubbins EJ , Helfrich RJ , Namovic MT , El-Kouhen OF , Masters JN , Brioni JD
Ref : Biochemical Pharmacology , 68 :761 , 2004
PubMedID: 15276084

Title : Dopamine D4 ligands and models of receptor activation: 2-(4-pyridin-2-ylpiperazin-1-ylmethyl)-1H-benzimidazole and related heteroarylmethylarylpiperazines exhibit a substituent effect responsible for additional efficacy tuning - Stewart_2004_J.Med.Chem_47_2348
Author(s) : Stewart AO , Cowart MD , Moreland RB , Latshaw SP , Matulenko MA , Bhatia PA , Wang X , Daanen JF , Nelson SL , Terranova MA , Namovic MT , Donnelly-Roberts D , Miller LN , Nakane M , Sullivan JP , Brioni JD
Ref : Journal of Medicinal Chemistry , 47 :2348 , 2004
PubMedID: 15084133

Title : Central mechanisms regulating penile erection in conscious rats: the dopaminergic systems related to the proerectile effect of apomorphine - Hsieh_2004_J.Pharmacol.Exp.Ther_308_330
Author(s) : Hsieh GC , Hollingsworth PR , Martino B , Chang R , Terranova MA , O'Neill AB , Lynch JJ , Moreland RB , Donnelly-Roberts D , Kolasa T , Mikusa JP , McVey JM , Marsh KC , Sullivan JP , Brioni JD
Ref : Journal of Pharmacology & Experimental Therapeutics , 308 :330 , 2004
PubMedID: 14569075

Title : A cell-based microarrayed compound screening format for identifying agonists of G-protein-coupled receptors - Gopalakrishnan_2003_Anal.Biochem_321_192
Author(s) : Gopalakrishnan SM , Moreland RB , Kofron JL , Helfrich RJ , Gubbins E , McGowen J , Masters JN , Donnelly-Roberts D , Brioni JD , Burns DJ , Warrior U
Ref : Analytical Biochemistry , 321 :192 , 2003
PubMedID: 14511684

Title : Functional characterization of the novel neuronal nicotinic acetylcholine receptor ligand GTS-21 in vitro and in vivo - Briggs_1997_Pharmacol.Biochem.Behav_57_231
Author(s) : Briggs CA , Anderson DJ , Brioni JD , Buccafusco JJ , Buckley MJ , Campbell JE , Decker MW , Donnelly-Roberts D , Elliott RL , Gopalakrishnan M , Holladay MW , Hui YH , Jackson WJ , Kim DJ , Marsh KC , O'Neill A , Prendergast MA , Ryther KB , Sullivan JP , Arneric SP
Ref : Pharmacol Biochem Behav , 57 :231 , 1997
PubMedID: 9164577

Title : Structure-activity studies on 2-methyl-3-(2(S)-pyrrolidinylmethoxy) pyridine (ABT-089): an orally bioavailable 3-pyridyl ether nicotinic acetylcholine receptor ligand with cognition-enhancing properties - Lin_1997_J.Med.Chem_40_385
Author(s) : Lin NH , Gunn DE , Ryther KB , Garvey DS , Donnelly-Roberts D , Decker MW , Brioni JD , Buckley MJ , Rodrigues AD , Marsh KG , Anderson DJ , Buccafusco JJ , Prendergast MA , Sullivan JP , Williams M , Arneric SP , Holladay MW
Ref : Journal of Medicinal Chemistry , 40 :385 , 1997
PubMedID: 9022806

Title : ABT-089 [2-methyl-3-(2-(S)-pyrrolidinylmethoxy)pyridine dihydrochloride]: II. A novel cholinergic channel modulator with effects on cognitive performance in rats and monkeys - Decker_1997_J.Pharmacol.Exp.Ther_283_247
Author(s) : Decker MW , Bannon AW , Curzon P , Gunther KL , Brioni JD , Holladay MW , Lin NH , Li Y , Daanen JF , Buccafusco JJ , Prendergast MA , Jackson WJ , Arneric SP
Ref : Journal of Pharmacology & Experimental Therapeutics , 283 :247 , 1997
PubMedID: 9336330

Title : Erysodine, a competitive antagonist at neuronal nicotinic acetylcholine receptors - Decker_1995_Eur.J.Pharmacol_280_79
Author(s) : Decker MW , Anderson DJ , Brioni JD , Donnelly-Roberts D , Kang CH , O'Neill AB , Piattoni-Kaplan M , Swanson S , Sullivan JP
Ref : European Journal of Pharmacology , 280 :79 , 1995
PubMedID: 7498257

Title : Cholinergic channel activators: novel opportunities for the treatment of CNS disorders - Sullivan_1995_Proc.West.Pharmacol.Soc_38_127
Author(s) : Sullivan JP , Decker MW , Donnelly-Roberts D , Brioni JD , Bannon AW , Holladay MW , Anderson DJ , Briggs CA , Williams M , Arneric SP
Ref : Proc West Pharmacol Soc , 38 :127 , 1995
PubMedID: 7480004

Title : Potential treatment of Alzheimer disease using cholinergic channel activators (ChCAs) with cognitive enhancement, anxiolytic-like, and cytoprotective properties - Arneric_1995_Alzheimer.Dis.Assoc.Disord_9 Suppl 2_50
Author(s) : Arneric SP , Sullivan JP , Decker MW , Brioni JD , Bannon AW , Briggs CA , Donnelly-Roberts D , Radek RJ , Marsh KC , Kyncl J , Williams M , Buccafusco JJ
Ref : Alzheimer Disease & Associated Disorders , 9 Suppl 2 :50 , 1995
PubMedID: 8534424

Title : Novel isoxazoles which interact with brain cholinergic channel receptors have intrinsic cognitive enhancing and anxiolytic activities -
Author(s) : Garvey DS , Wasicak JT , Decker MW , Brioni JD , Buckley MJ , Sullivan JP , Carrera GM , Holladay MW , Arneric SP , Williams M
Ref : Journal of Medicinal Chemistry , 37 :1055 , 1994
PubMedID: 7909335

Title : (+\/-)-Epibatidine elicits a diversity of in vitro and in vivo effects mediated by nicotinic acetylcholine receptors - Sullivan_1994_J.Pharmacol.Exp.Ther_271_624
Author(s) : Sullivan JP , Decker MW , Brioni JD , Donnelly-Roberts D , Anderson DJ , Bannon AW , Kang CH , Adams P , Piattoni-Kaplan M , Buckley MJ
Ref : Journal of Pharmacology & Experimental Therapeutics , 271 :624 , 1994
PubMedID: 7965777