Title : Synthesis of imidazopyridines and purines as potent inhibitors of leukotriene A4 hydrolase - Penning_2003_Bioorg.Med.Chem.Lett_13_1137 |
Author(s) : Penning TD , Chandrakumar NS , Desai BN , Djuric SW , Gasiecki AF , Malecha JW , Miyashiro JM , Russell MA , Askonas LJ , Gierse JK , Harding EI , Highkin MK , Kachur JF , Kim SH , Villani-Price D , Pyla EY , Ghoreishi-Haack NS , Smith WG |
Ref : Bioorganic & Medicinal Chemistry Lett , 13 :1137 , 2003 |
Abstract : |
PubMedSearch : Penning_2003_Bioorg.Med.Chem.Lett_13_1137 |
PubMedID: 12643929 |
Title : Pharmacological characterization of SC-57461A (3-[methyl[3-[4-(phenylmethyl)phenoxy]propyl]amino]propanoic acid HCl), a potent and selective inhibitor of leukotriene A(4) hydrolase II: in vivo studies - Kachur_2002_J.Pharmacol.Exp.Ther_300_583 |
Author(s) : Kachur JF , Askonas LJ , Villani-Price D , Ghoreishi-Haack N , Won-Kim S , Liang CD , Russell MA , Smith WG |
Ref : Journal of Pharmacology & Experimental Therapeutics , 300 :583 , 2002 |
Abstract : |
PubMedSearch : Kachur_2002_J.Pharmacol.Exp.Ther_300_583 |
PubMedID: 11805220 |
Title : Pharmacological characterization of SC-57461A (3-[methyl[3-[4-(phenylmethyl)phenoxy]propyl]amino]propanoic acid HCl), a potent and selective inhibitor of leukotriene A(4) hydrolase I: in vitro studies - Askonas_2002_J.Pharmacol.Exp.Ther_300_577 |
Author(s) : Askonas LJ , Kachur JF , Villani-Price D , Liang CD , Russell MA , Smith WG |
Ref : Journal of Pharmacology & Experimental Therapeutics , 300 :577 , 2002 |
Abstract : |
PubMedSearch : Askonas_2002_J.Pharmacol.Exp.Ther_300_577 |
PubMedID: 11805219 |
Title : Pyrrolidine and piperidine analogues of SC-57461A as potent, orally active inhibitors of leukotriene A(4) hydrolase - Penning_2002_Bioorg.Med.Chem.Lett_12_3383 |
Author(s) : Penning TD , Chandrakumar NS , Desai BN , Djuric SW , Gasiecki AF , Liang CD , Miyashiro JM , Russell MA , Askonas LJ , Gierse JK , Harding EI , Highkin MK , Kachur JF , Kim SH , Villani-Price D , Pyla EY , Ghoreishi-Haack NS , Smith WG |
Ref : Bioorganic & Medicinal Chemistry Lett , 12 :3383 , 2002 |
Abstract : |
PubMedSearch : Penning_2002_Bioorg.Med.Chem.Lett_12_3383 |
PubMedID: 12419366 |
Title : Synthesis of potent leukotriene A(4) hydrolase inhibitors. Identification of 3-[methyl[3-[4-(phenylmethyl)phenoxy]propyl]amino]propanoic acid - Penning_2002_J.Med.Chem_45_3482 |
Author(s) : Penning TD , Russell MA , Chen BB , Chen HY , Liang CD , Mahoney MW , Malecha JW , Miyashiro JM , Yu SS , Askonas LJ , Gierse JK , Harding EI , Highkin MK , Kachur JF , Kim SH , Villani-Price D , Pyla EY , Ghoreishi-Haack NS , Smith WG |
Ref : Journal of Medicinal Chemistry , 45 :3482 , 2002 |
Abstract : |
PubMedSearch : Penning_2002_J.Med.Chem_45_3482 |
PubMedID: 12139459 |
Title : Structure-activity relationship studies on 1-[2-(4-Phenylphenoxy)ethyl]pyrrolidine (SC-22716), a potent inhibitor of leukotriene A(4) (LTA(4)) hydrolase - Penning_2000_J.Med.Chem_43_721 |
Author(s) : Penning TD , Chandrakumar NS , Chen BB , Chen HY , Desai BN , Djuric SW , Docter SH , Gasiecki AF , Haack RA , Miyashiro JM , Russell MA , Yu SS , Corley DG , Durley RC , Kilpatrick BF , Parnas BL , Askonas LJ , Gierse JK , Harding EI , Highkin MK , Kachur JF , Kim SH , Krivi GG , Villani-Price D , Pyla EY , Smith WG |
Ref : Journal of Medicinal Chemistry , 43 :721 , 2000 |
Abstract : |
PubMedSearch : Penning_2000_J.Med.Chem_43_721 |
PubMedID: 10691697 |
Title : Enantiomers of oxybutynin: in vitro pharmacological characterization at M1, M2 and M3 muscarinic receptors and in vivo effects on urinary bladder contraction, mydriasis and salivary secretion in guinea pigs - Noronha-Blob_1991_J.Pharmacol.Exp.Ther_256_562 |
Author(s) : Noronha-Blob L , Kachur JF |
Ref : Journal of Pharmacology & Experimental Therapeutics , 256 :562 , 1991 |
Abstract : |
PubMedSearch : Noronha-Blob_1991_J.Pharmacol.Exp.Ther_256_562 |
PubMedID: 1993995 |
Title : Regulation of guinea pig ileal electrolyte transport by M3-muscarinic acetylcholine receptors in vitro - Kachur_1990_Mol.Pharmacol_38_836 |
Author(s) : Kachur JF , Sturm BL , Gaginella TS , Noronha-Blob L |
Ref : Molecular Pharmacology , 38 :836 , 1990 |
Abstract : |
PubMedSearch : Kachur_1990_Mol.Pharmacol_38_836 |
PubMedID: 2250664 |
Title : In vitro and in vivo antimuscarinic effects of (-)cis 2,3-dihydro-3-(4-methylpiperazinylmethyl)-2-phenyl-1,5 benzothiazepin-4-(5H)one HCl (BTM-1086) in guinea pig peripheral tissues - Noronha-Blob_1990_Life.Sci_46_1223 |
Author(s) : Noronha-Blob L , Sturm BL , Lowe VC , Jackson KN , Kachur JF |
Ref : Life Sciences , 46 :1223 , 1990 |
Abstract : |
PubMedSearch : Noronha-Blob_1990_Life.Sci_46_1223 |
PubMedID: 2338887 |
Title : R and S enantiomers of oxybutynin: pharmacological effects in guinea pig bladder and intestine - Kachur_1988_J.Pharmacol.Exp.Ther_247_867 |
Author(s) : Kachur JF , Peterson JS , Carter JP , Rzeszotarski WJ , Hanson RC , Noronha-Blob L |
Ref : Journal of Pharmacology & Experimental Therapeutics , 247 :867 , 1988 |
Abstract : |
PubMedSearch : Kachur_1988_J.Pharmacol.Exp.Ther_247_867 |
PubMedID: 2849672 |