Full name : Koelle George Brampton
First name : George Brampton
Mail : Dpt. of Pharmacology. School of Medicine, University of Pennsylvania. 36th & Hamilton, Walk, Philadelphia. PA 19104-6084
Zip Code :
City :
Country : USA
Email :
Phone : (I) 2158988418
Fax : (I) 215 898 9927
Website : \/\/www.nasonline.org\/publications\/biographical-memoirs\/memoir-pdfs\/koelle-george.pdf
Directory :
Comment
George Brampton Koelle was born in 1918 and died in 1997 in Philadelphia. Koelle with Friedenwald invented the Koelle technique which involved exposure of a tissue section to thio analogues of acetyl, benzoyl, and butyrycholine. The enzyme hydrolyzes the substrate, liberates thiocholine as a mercaptide, which is then replaced by cupric sulfide, resulting in a black precipitate that localizes the choline esterase.
| Title : Pharmacology of organophosphates - Koelle_1994_J.Appl.Toxicol_14_105 |
| Author(s) : Koelle GB |
| Ref : J Appl Toxicol , 14 :105 , 1994 |
| Abstract : |
| PubMedSearch : Koelle_1994_J.Appl.Toxicol_14_105 |
| PubMedID: 8027504 |
| Title : Neurotrophic Actions of Glycyl-I-Glutamine - |
| Author(s) : Koelle GB |
| Ref : In: Cholinesterases: Structure, Function, Mechanism, Genetics, and Cell Biology , (Massoulie J, Barnard EA, Chatonnet A, Bacou F, Doctor BP, Quinn DM) American Chemical Society, Washington, DC :339 , 1991 |
| PubMedID: |
| Title : Effects of glycyl-L-glutamine and methylprednisolone on maintenance of acetylcholinesterase of transected rat sciatic nerves - Koelle_1990_Proc.Natl.Acad.Sci.U.S.A_87_9495 |
| Author(s) : Koelle GB , Han MS |
| Ref : Proceedings of the National Academy of Sciences of the United States of America , 87 :9495 , 1990 |
| Abstract : |
| PubMedSearch : Koelle_1990_Proc.Natl.Acad.Sci.U.S.A_87_9495 |
| PubMedID: 2251290 |
| Title : Histochemical demonstration of neurotoxic esterase - Koelle_1989_J.Histochem.Cytochem_37_589 |
| Author(s) : Koelle GB , Thampi NS , Han MS , Olajos EJ |
| Ref : Journal of Histochemistry & Cytochemistry , 37 :589 , 1989 |
| Abstract : |
| PubMedSearch : Koelle_1989_J.Histochem.Cytochem_37_589 |
| PubMedID: 2703698 |
| Title : Effect of glycyl-L-glutamine on the rate of regeneration of acetylcholinesterase in the rat gastrocnemius muscle after diisopropyl phosphorofluoridate administration - Koelle_1989_Proc.Natl.Acad.Sci.U.S.A_86_4331 |
| Author(s) : Koelle GB , Han MS |
| Ref : Proceedings of the National Academy of Sciences of the United States of America , 86 :4331 , 1989 |
| Abstract : |
| PubMedSearch : Koelle_1989_Proc.Natl.Acad.Sci.U.S.A_86_4331 |
| PubMedID: 2726774 |
| Title : Effects of glycyl-L-glutamine in vitro on the molecular forms of acetylcholinesterase in the preganglionically denervated superior cervical ganglion of the cat - Koelle_1988_Proc.Natl.Acad.Sci.U.S.A_85_1686 |
| Author(s) : Koelle GB , Massoulie J , Eugene D , Melone MA |
| Ref : Proceedings of the National Academy of Sciences of the United States of America , 85 :1686 , 1988 |
| Abstract : |
| PubMedSearch : Koelle_1988_Proc.Natl.Acad.Sci.U.S.A_85_1686 |
| PubMedID: 3422756 |
| Title : Maintenance by glycyl-L-glutamine in vivo of molecular forms of acetylcholinesterase in the preganglionically denervated superior cervical ganglion of the cat - Koelle_1988_Proc.Natl.Acad.Sci.U.S.A_85_6215 |
| Author(s) : Koelle GB , Skau KA , Thampi NS , Hymel DM , Han MS |
| Ref : Proceedings of the National Academy of Sciences of the United States of America , 85 :6215 , 1988 |
| Abstract : |
| PubMedSearch : Koelle_1988_Proc.Natl.Acad.Sci.U.S.A_85_6215 |
| PubMedID: 3413090 |
| Title : Direct neurotrophic action of glycyl-L-glutamine in the maintenance of acetylcholinesterase and butyrylcholinesterase in the preganglionically denervated superior cervical ganglion of the cat - Koelle_1987_Proc.Natl.Acad.Sci.U.S.A_84_6944 |
| Author(s) : Koelle GB , Sanville UJ , Thampi NS |
| Ref : Proceedings of the National Academy of Sciences of the United States of America , 84 :6944 , 1987 |
| Abstract : |
| PubMedSearch : Koelle_1987_Proc.Natl.Acad.Sci.U.S.A_84_6944 |
| PubMedID: 3477818 |
| Title : Distributions of molecular forms of acetylcholinesterase and butyrylcholinesterase in nervous tissue of the cat - Koelle_1987_Proc.Natl.Acad.Sci.U.S.A_84_7749 |
| Author(s) : Koelle GB , Massoulie J , Eugene D , Melone MA , Boulla G |
| Ref : Proceedings of the National Academy of Sciences of the United States of America , 84 :7749 , 1987 |
| Abstract : |
| PubMedSearch : Koelle_1987_Proc.Natl.Acad.Sci.U.S.A_84_7749 |
| PubMedID: 3478723 |
| Title : An Endogenous Neurotrophic Factor for the Maintenance of Acetylcholinesterase and Butyrylcholinesterase in the Preganglionically Denervated Superior Cervical Ganglion of the Cat - |
| Author(s) : Koelle GB , Ruch GA , Uchida E , Davis R , Koelle WA , Rickard KK |
| Ref : Advances in Behavioral Biology , 30 :733 , 1986 |
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| Title : L-glutamic acid, a neurotrophic factor for maintenance of acetylcholinesterase and butyrylcholinesterase in the preganglionically denervated superior cervical ganglion of the cat - Koelle_1986_Proc.Natl.Acad.Sci.U.S.A_83_2751 |
| Author(s) : Koelle GB , Sanville UJ , Thampi NS , Wall SJ |
| Ref : Proceedings of the National Academy of Sciences of the United States of America , 83 :2751 , 1986 |
| Abstract : |
| PubMedSearch : Koelle_1986_Proc.Natl.Acad.Sci.U.S.A_83_2751 |
| PubMedID: 3458234 |
| Title : Glycyl-L-glutamine, a precursor, and glycyl-L-glutamic acid, a neurotrophic factor for maintenance of acetylcholinesterase and butyrylcholinesterase in the preganglionically denervated superior cervical ganglion of the cat in vivo - Koelle_1985_Proc.Natl.Acad.Sci.U.S.A_82_5213 |
| Author(s) : Koelle GB , Sanville UJ , Wall SJ |
| Ref : Proceedings of the National Academy of Sciences of the United States of America , 82 :5213 , 1985 |
| Abstract : |
| PubMedSearch : Koelle_1985_Proc.Natl.Acad.Sci.U.S.A_82_5213 |
| PubMedID: 3860856 |
| Title : Demonstration of a neurotrophic factor for the maintenance of acetylcholinesterase and butyrylcholinesterase in the preganglionically denervated superior cervical ganglion of the cat - |
| Author(s) : Koelle GB , Ruch GA , Uchida E |
| Ref : In: Cholinesterases, fundamental and applied aspects : proceedings of the Second International Meeting on Cholinesterases , (Brzin M, Barnard EA, Sket D, Eds) De Gruyter :309 , 1984 |
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| Title : Electron microscope localization of acetylcholinesterase and butyrylcholinesterase in the ciliary ganglion of the cat - Davis_1984_J.Histochem.Cytochem_32_849 |
| Author(s) : Davis R , Koelle GB , Sanville UJ |
| Ref : Journal of Histochemistry & Cytochemistry , 32 :849 , 1984 |
| Abstract : |
| PubMedSearch : Davis_1984_J.Histochem.Cytochem_32_849 |
| PubMedID: 6205047 |
| Title : Partial characterization of the neurotrophic factor for maintenance of acetylcholinesterase and butyrylcholinesterase in the preganglionically denervated superior cervical ganglion of the cat in vivo - Koelle_1984_Proc.Natl.Acad.Sci.U.S.A_81_6539 |
| Author(s) : Koelle GB , Sanville UJ , Rickard KK , Williams JE |
| Ref : Proceedings of the National Academy of Sciences of the United States of America , 81 :6539 , 1984 |
| Abstract : |
| PubMedSearch : Koelle_1984_Proc.Natl.Acad.Sci.U.S.A_81_6539 |
| PubMedID: 6093105 |
| Title : Demonstration of a neurotrophic factor for the maintenance of acetylcholinesterase and butyrylcholinesterase in the preganglionically denervated superior cervical ganglion of the cat - Koelle_1983_Proc.Natl.Acad.Sci.U.S.A_80_3106 |
| Author(s) : Koelle GB , Ruch GA |
| Ref : Proceedings of the National Academy of Sciences of the United States of America , 80 :3106 , 1983 |
| Abstract : |
| PubMedSearch : Koelle_1983_Proc.Natl.Acad.Sci.U.S.A_80_3106 |
| PubMedID: 6190171 |
| Title : Effects of sodium pentobarbital anesthesia and neurotrophic factor on the maintenance of acetylcholinesterase and butyrylcholinesterase in the preganglionically denervated superior cervical ganglion of the cat - Koelle_1983_Proc.Natl.Acad.Sci.U.S.A_80_6122 |
| Author(s) : Koelle GB , Ruch GA , Uchida E |
| Ref : Proceedings of the National Academy of Sciences of the United States of America , 80 :6122 , 1983 |
| Abstract : |
| PubMedSearch : Koelle_1983_Proc.Natl.Acad.Sci.U.S.A_80_6122 |
| PubMedID: 6577471 |
| Title : Identification of the probable site of synthesis of butyrylcholinesterase in the superior cervical and ciliary ganglia of the cat - Uchida_1983_Proc.Natl.Acad.Sci.U.S.A_80_6723 |
| Author(s) : Uchida E , Koelle GB |
| Ref : Proceedings of the National Academy of Sciences of the United States of America , 80 :6723 , 1983 |
| Abstract : |
| PubMedSearch : Uchida_1983_Proc.Natl.Acad.Sci.U.S.A_80_6723 |
| PubMedID: 6579557 |
| Title : Regeneration of cholinesterases in the stellate and normal and denervated superior cervical ganglion of the cat following inactivation by sarin - Koelle_1982_J.Neurochem_38_1695 |
| Author(s) : Koelle GB , Ruch GA , Rickard KK , Sanville UJ |
| Ref : Journal of Neurochemistry , 38 :1695 , 1982 |
| Abstract : |
| PubMedSearch : Koelle_1982_J.Neurochem_38_1695 |
| PubMedID: 7077333 |
| Title : Effects of selective alkylphosphorylation of propionylcholinesterase on the regeneration of acetylcholinesterase in the aqueous soluble fraction of superior cervical ganglia of the rat following sarin - Koelle_1981_J.Neurochem_36_402 |
| Author(s) : Koelle WA , Rickard KK , Koelle GB |
| Ref : Journal of Neurochemistry , 36 :402 , 1981 |
| Abstract : |
| PubMedSearch : Koelle_1981_J.Neurochem_36_402 |
| PubMedID: 7463067 |
| Title : Electron microscope localization of acetylcholinesterase and butyrylcholinesterase in the superior cervical ganglion of the cat. II. Preganglionically denervated ganglion - Davis_1981_J.Cell.Biol_88_581 |
| Author(s) : Davis R , Koelle GB |
| Ref : Journal of Cell Biology , 88 :581 , 1981 |
| Abstract : |
| PubMedSearch : Davis_1981_J.Cell.Biol_88_581 |
| PubMedID: 7217205 |
| Title : Questions Raised by the Electron Microscopic Localization of Acetylcholinesterase and Butyrylcholinesterase in Normal and Denervated Superior Cervical Ganglia in the Cat - |
| Author(s) : Koelle GB , Davis R , Koelle WA , Ruch GA , Rickard KK , Sanville UJ |
| Ref : Advances in Behavioral Biology , 25 :127 , 1981 |
| PubMedID: |
| Title : Interrelationships between ganglionic acetylcholinesterase and nonspecific cholinesterase of the cat and rat - Koelle_1979_Proc.Natl.Acad.Sci.U.S.A_76_6012 |
| Author(s) : Koelle GB , Rickard KK , Ruch GA |
| Ref : Proceedings of the National Academy of Sciences of the United States of America , 76 :6012 , 1979 |
| Abstract : |
| PubMedSearch : Koelle_1979_Proc.Natl.Acad.Sci.U.S.A_76_6012 |
| PubMedID: 293697 |
| Title : Steady state and regenerating levels of acetylcholinesterase in the superior cervical ganglion of the rat following selective inactivation of propionylcholinesterase - |
| Author(s) : Koelle GB , Rickard KK , Smyrl EG |
| Ref : Journal of Neurochemistry , 33 :1159 , 1979 |
| PubMedID: 552398 |
| Title : Electron microscope localization of acetylcholinesterase and butyrylcholinesterase in the superior cervical ganglion of the cat. I. Normal ganglion - Davis_1978_J.Cell.Biol_78_785 |
| Author(s) : Davis R , Koelle GB |
| Ref : Journal of Cell Biology , 78 :785 , 1978 |
| Abstract : |
| PubMedSearch : Davis_1978_J.Cell.Biol_78_785 |
| PubMedID: 701360 |
| Title : Effects of inactivation of butyrylcholinesterase on steady state and regenerating levels of ganglionic acetylcholinesterase - Koelle_1977_J.Neurochem_28_313 |
| Author(s) : Koelle GB , Koelle WA , Smyrl EG |
| Ref : Journal of Neurochemistry , 28 :313 , 1977 |
| Abstract : |
| PubMedSearch : Koelle_1977_J.Neurochem_28_313 |
| PubMedID: 839215 |
| Title : Effects of persistent selective suppression of ganglionic butyrylcholinesterase on steady state and regenerating levels of acetylcholinesterase: implications regarding function of butyrylcholinesterase and regulation of protein synthesis - Koelle_1976_Proc.Natl.Acad.Sci.U.S.A_73_2936 |
| Author(s) : Koelle WA , Koelle GB , Smyrl EG |
| Ref : Proceedings of the National Academy of Sciences of the United States of America , 73 :2936 , 1976 |
| Abstract : |
| PubMedSearch : Koelle_1976_Proc.Natl.Acad.Sci.U.S.A_73_2936 |
| PubMedID: 1066704 |
| Title : Selective, near-total, irreversible inactivation of peripheral pseudocholinesterase and acetylcholinesterase in cats in vivo - |
| Author(s) : Koelle GB , Davis R , Diliberto EJJr , Koelle WA |
| Ref : Biochemical Pharmacology , 23 :175 , 1974 |
| PubMedID: 4360344 |
| Title : Histochemical evidence and consequences of the occurrence of isoenzymes of acetylcholinesterase - |
| Author(s) : Koelle WA , Hossaini KS , Akbarzadeh P , Koelle GB |
| Ref : Journal of Histochemistry & Cytochemistry , 18 :812 , 1970 |
| PubMedID: 5504516 |
| Title : Improvement in the accuracy of histochemical localization of acetylcholinesterase. Facts and artifacts - |
| Author(s) : Koelle GB |
| Ref : Drugs and Cholinergic Mechanisms in the CNS :431 , 1970 |
| PubMedID: |
| Title : Renshaw elements: localisation and acetylcholinesterase content - |
| Author(s) : Erulkar SD , Nichols CW , Popp MB , Koelle GB |
| Ref : Journal of Histochemistry & Cytochemistry , 16 :128 , 1968 |
| PubMedID: |
| Title : Comparison of the localization of acetylcholinesterase and non-specific cholinesterase activities in mammalian and avian retinas - |
| Author(s) : Nichols CW , Koelle GB |
| Ref : Journal of Comparative Neurology , 133 :1 , 1968 |
| PubMedID: 4181137 |
| Title : A thiocholine-lead ferrocyanide method for acetylcholinesterase - |
| Author(s) : Ernko O , Koelle GB , Rausanen L |
| Ref : Journal of Histochemistry & Cytochemistry , 15 :674 , 1967 |
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| Title : Electron microscopie localization of cholinesterases by means of gold salts - |
| Author(s) : Koelle GB , Davis R , Gromadzki CG |
| Ref : Annals of the New York Academy of Sciences , 144 :613 , 1967 |
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| Title : Acetylcholinesterase: method for demonstration in amacrine cells of rabbit retina - Nichols_1967_Science_155_477 |
| Author(s) : Nichols CW , Koelle GB |
| Ref : Science , 155 :477 , 1967 |
| Abstract : |
| PubMedSearch : Nichols_1967_Science_155_477 |
| PubMedID: 6015699 |
| Title : Electron microscopic localization of acetylcholinesterase and nonspecific cholinesterase at the neuromuscular junction by the gold-thiocholine and gold-thiolacetic acid methods - Davis_1967_J.Cell.Biol_34_157 |
| Author(s) : Davis R , Koelle GB |
| Ref : Journal of Cell Biology , 34 :157 , 1967 |
| Abstract : |
| PubMedSearch : Davis_1967_J.Cell.Biol_34_157 |
| PubMedID: 6033530 |
| Title : Acetylcholine relcase from the cat superior cervical ganglion by carbachol - |
| Author(s) : Mckinstry DN , Koelle GB |
| Ref : Journal of Pharmacology & Experimental Therapeutics , 157 :319 , 1967 |
| PubMedID: |
| Title : A thiocholine-lead ferrocyanide method for acetylcholinesterase - |
| Author(s) : Eranko O , Koelle GB , Raisanen L |
| Ref : Journal of Histochemistry & Cytochemistry , 15 :674 , 1967 |
| PubMedID: 4172645 |
| Title : Comparison of the gold-thiocholine and gold-thiolacetic acid methods for the histochemical localisation of acetylcholinesterase and cholinesterases - |
| Author(s) : Koelle GB , Gromadzki CG |
| Ref : Journal of Histochemistry & Cytochemistry , 14 :443 , 1966 |
| PubMedID: 5336476 |
| Title : Histochemical correlations of acetylcholinesterase and catecholamines in post-ganglionic autonomic nerves of the cat, rabbit, and guinea pig - |
| Author(s) : Jacobowitz D , Koelle GB |
| Ref : Journal of Pharmacology & Experimental Therapeutics , 148 :225 , 1965 |
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| Title : The effect of axotomy on the acetylcholinesterase of the superior cervical ganglion of the cat - |
| Author(s) : Gromadzki CG , Koelle GB |
| Ref : Biochemical Pharmacology , 14 :1745 , 1965 |
| PubMedID: 5880532 |
| Title : Cytological distributions and physiological fonctions of cholinesterases - |
| Author(s) : Koelle GB |
| Ref : Handbook of Experimental Pharmacology , 15 :187 , 1963 |
| PubMedID: |
| Title : Anticholinesterase agents - |
| Author(s) : Koelle GB , Volle RB , Holmstedt B , Karczmar AG , O'Brien RD |
| Ref : Science , 141 :63 , 1963 |
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| Title : A new general concept of the neurohumoral fonctions of acetylcholine and acetylcholinesterase - |
| Author(s) : Koelle GB |
| Ref : J Pharm Pharmacol , 14 :65 , 1962 |
| PubMedID: |
| Title : A proposed dual neurohumoral role of acetylcholine, its functions at pre- and post-synaptic sites - |
| Author(s) : Koelle GB |
| Ref : Nature , 190 :208 , 1961 |
| PubMedID: |
| Title : Comparison of the effects of inhibition of internal and total acetylcholinesterase upon ganglionic transmission - |
| Author(s) : Melsaac RJ , Koelle GB |
| Ref : Journal of Pharmacology & Experimental Therapeutics , 126 :9 , 1959 |
| PubMedID: |
| Title : Reactivation of DFP-inactivated acetylcholinesterase by monoisonitrosoacetone (MINA) and diacetylmonoxime (DAM) in vivo - |
| Author(s) : Rajapurkar MV , Koelle GB |
| Ref : Journal of Pharmacology & Experimental Therapeutics , 123 :247 , 1958 |
| PubMedID: 13564402 |
| Title : Histochemical demonstration of reversible anti-cholinesterase action at selective cellular sites in vivo - |
| Author(s) : Koelle GB |
| Ref : Journal of Pharmacology & Experimental Therapeutics , 120 :488 , 1957 |
| PubMedID: |
| Title : Histochemical demonstration of reactivation of acetylcholinesterase in vivo - |
| Author(s) : Koelle GB |
| Ref : Science , 125 :1195 , 1957 |
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| Title : The cerebral distributions of a tertiary and a quaternary anticholinesterase agent following intravenous and intraventricular injection - |
| Author(s) : Koelle GB , Steiner EC |
| Ref : Journal of Pharmacology & Experimental Therapeutics , 118 :420 , 1956 |
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| Title : The histochemical identification of cholinesterase in cholinergic, adrenergic and sensory neurons - |
| Author(s) : Koelle GB |
| Ref : Journal of Pharmacology & Experimental Therapeutics , 114 :167 , 1955 |
| PubMedID: |
| Title : The histochemical localisation of cholinesterases in the central nervous system of the rat - |
| Author(s) : Koelle GB |
| Ref : Journal of Comparative Neurology , 100 :211 , 1954 |
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| Title : Localization of specific cholinesterase in ocular tissues of the cat - |
| Author(s) : Koelle GB , Wolfand L , Friedenwald JS , Allen RA |
| Ref : American Journal of Ophthalmology , 35 :1580 , 1952 |
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| Title : The elimination of enzymatic diffusion artifacts in the histochemical localisation of cholinesterases and a survey of their cellular distributions - |
| Author(s) : Koelle GB |
| Ref : Journal of Pharmacology & Experimental Therapeutics , 103 :153 , 1951 |
| PubMedID: |
| Title : Histochemical localisation of cholinesterase in ocular tissue - |
| Author(s) : Koelle GB , Friedenwald JS |
| Ref : American Journal of Ophthalmology , 33 :253 , 1950 |
| PubMedID: |
| Title : The histochemical differentiation of types of cholinesterases and their localisations in tissues of the cat - |
| Author(s) : Koelle GB |
| Ref : Journal of Pharmacology & Experimental Therapeutics , 100 :158 , 1950 |
| PubMedID: |
| Title : A histochemical method for localizing cholinesterase activity - |
| Author(s) : Koelle GB , Friedenwald JS |
| Ref : Proceedings of the Society for Experimental Biology & Medicine , 70 :617 , 1949 |
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| Title : The pharmacology of di-isopropyl fluorophosphate (DFP) in man - |
| Author(s) : Comroe JH, Jr. , Todd J , Koelle GB |
| Ref : Journal of Pharmacology & Experimental Therapeutics , 87 :281 , 1946 |
| PubMedID: 20994729 |
| Title : The acute toxicity of diisopropylfluorophosphate - Horton_1946_J.Pharmacol.Exp.Therap_87_414 |
| Author(s) : Horton RG , Koelle GB , Mcnamara BP , Pratt HJ |
| Ref : Journal of Pharmacology & Experimental Therapeutics , 87 :414 , 1946 |
| Abstract : |
| PubMedSearch : Horton_1946_J.Pharmacol.Exp.Therap_87_414 |
| PubMedID: 20279262 |
| Title : Nerve conduction in the absence of cholinesterase activity induced by di-isopropyl fluorophosphate - |
| Author(s) : Crescitelli F , Koelle GB , Gilman A |
| Ref : Federation Proceedings , 5 :172 , 1946 |
| PubMedID: 21064298 |
| Title : Protection of cholinesterase against irreversible inactivation by DFP in vitro - |
| Author(s) : Koelle GB |
| Ref : Journal of Pharmacology & Experimental Therapeutics , 88 :323 , 1946 |
| PubMedID: |
| Title : Transmission of impulses in peripheral nerves treated with diisopropyl fluorophosphate (DFP) - |
| Author(s) : Crescitelli F , Koelle GB , Gilman A |
| Ref : Journal of Neurophysiology , 9 :241 , 1946 |
| PubMedID: |