| Title : Lead optimization of rivastigmine-like hybrids: Impact of nitro group and halogen substitution on multi-target anti-Alzheimer's activity - Leuci_2026_Bioorg.Med.Chem_141_118760 |
| Author(s) : Leuci R , Paparella M , Cerini M , Simic S , Chaves S , Carrieri A , Tortorella P , Loiodice F , Laghezza A , Santos MA , Wackerlig-Damle J , Piemontese L |
| Ref : Bioorganic & Medicinal Chemistry , 141 :118760 , 2026 |
| Abstract : |
| PubMedSearch : Leuci_2026_Bioorg.Med.Chem_141_118760 |
| PubMedID: 42531673 |
| Title : Structural optimization of donepezil-like hybrids toward an improved multi-target and ADME-related profile - Paparella_2026_Bioorg.Chem_183_110599 |
| Author(s) : Paparella M , Leuci R , Cerini M , Simic S , Chaves S , Carrieri A , Loiodice F , Tortorella P , Laghezza A , Wackerlig-Damle J , Santos MA , Piemontese L |
| Ref : Bioorg Chem , 183 :110599 , 2026 |
| Abstract : |
| PubMedSearch : Paparella_2026_Bioorg.Chem_183_110599 |
| PubMedID: 42826663 |
| Title : Rivastigmine structure-based hybrids as potential multi-target anti-Alzheimer's drug candidates - Leuci_2024_Bioorg.Chem_153_107895 |
| Author(s) : Leuci R , Simic S , Carrieri A , Chaves S , La Spada G , Brunetti L , Tortorella P , Loiodice F , Laghezza A , Catto M , Santos MA , Tufarelli V , Wackerlig J , Piemontese L |
| Ref : Bioorg Chem , 153 :107895 , 2024 |
| Abstract : |
| PubMedSearch : Leuci_2024_Bioorg.Chem_153_107895 |
| PubMedID: 39454499 |
| Title : Novel Phenothiazine\/Donepezil-like Hybrids Endowed with Antioxidant Activity for a Multi-Target Approach to the Therapy of Alzheimer's Disease - Carocci_2022_Antioxidants.(Basel)_11_ |
| Author(s) : Carocci A , Barbarossa A , Leuci R , Carrieri A , Brunetti L , Laghezza A , Catto M , Limongelli F , Chaves S , Tortorella P , Altomare CD , Santos MA , Loiodice F , Piemontese L |
| Ref : Antioxidants (Basel) , 11 : , 2022 |
| Abstract : |
| PubMedSearch : Carocci_2022_Antioxidants.(Basel)_11_ |
| PubMedID: 36139705 |
| Title : A New Series of Aryloxyacetic Acids Endowed with Multi-Target Activity towards Peroxisome Proliferator-Activated Receptors (PPARs), Fatty Acid Amide Hydrolase (FAAH), and Acetylcholinesterase (AChE) - Leuci_2022_Molecules_27_ |
| Author(s) : Leuci R , Brunetti L , Laghezza A , Piemontese L , Carrieri A , Pisani L , Tortorella P , Catto M , Loiodice F |
| Ref : Molecules , 27 : , 2022 |
| Abstract : |
| PubMedSearch : Leuci_2022_Molecules_27_ |
| PubMedID: 35164223 |
| Title : Structure-based design of novel donepezil-like hybrids for a multi-target approach to the therapy of Alzheimer's disease - Brunetti_2022_Eur.J.Med.Chem_237_114358 |
| Author(s) : Brunetti L , Leuci R , Carrieri A , Catto M , Occhineri S , Vinci G , Gambacorta L , Baltrukevich H , Chaves S , Laghezza A , Altomare CD , Tortorella P , Santos MA , Loiodice F , Piemontese L |
| Ref : Eur Journal of Medicinal Chemistry , 237 :114358 , 2022 |
| Abstract : |
| PubMedSearch : Brunetti_2022_Eur.J.Med.Chem_237_114358 |
| PubMedID: 35462163 |