Meek EC

References (19)

Title : Pharmacokinetics of three novel pyridinium aldoxime acetylcholinesterase reactivators in female rats - Backer_2022_Toxicol.Appl.Pharmacol_446_116046
Author(s) : Backer BS , Meek EC , Ross MK , Chambers JE
Ref : Toxicol Appl Pharmacol , 446 :116046 , 2022
Abstract :
PubMedSearch : Backer_2022_Toxicol.Appl.Pharmacol_446_116046
PubMedID: 35550885

Title : In vitro age-related differences in rats to organophosphates - Meek_2021_Toxicol.In.Vitro__105102
Author(s) : Meek EC , Carr RL , Chambers JE
Ref : Toxicol In Vitro , :105102 , 2021
Abstract :
PubMedSearch : Meek_2021_Toxicol.In.Vitro__105102
PubMedID: 33497710

Title : Inhibition Kinetics of 16 Organophosphorus Pesticides or Their Active Metabolites on Erythrocyte Acetylcholinesterase from Humans and Rats - Meek_2021_Toxicol.Sci__
Author(s) : Meek EC , Reiss R , Crow JA , Chambers JE
Ref : Toxicol Sci , : , 2021
Abstract :
PubMedSearch : Meek_2021_Toxicol.Sci__
PubMedID: 33720374

Title : Central neuroprotection demonstrated by novel oxime countermeasures to nerve agent surrogates - Chambers_2020_Ann.N.Y.Acad.Sci__
Author(s) : Chambers JE , Meek EC
Ref : Annals of the New York Academy of Sciences , : , 2020
Abstract :
PubMedSearch : Chambers_2020_Ann.N.Y.Acad.Sci__
PubMedID: 32319115

Title : Oxime-mediated reactivation of organophosphate-inhibited acetylcholinesterase with emphasis on centrally-active oximes - Chambers_2020_Neuropharmacol__108201
Author(s) : Chambers JE , Dail MB , Meek EC
Ref : Neuropharmacology , :108201 , 2020
Abstract :
PubMedSearch : Chambers_2020_Neuropharmacol__108201
PubMedID: 32544483

Title : Novel centrally active oxime reactivators of acetylcholinesterase inhibited by surrogates of sarin and VX - Chambers_2019_Neurobiol.Dis__104487
Author(s) : Chambers JE , Meek EC
Ref : Neurobiol Dis , :104487 , 2019
Abstract :
PubMedSearch : Chambers_2019_Neurobiol.Dis__104487
PubMedID: 31158460

Title : Novel Brain-Penetrating Oxime Acetylcholinesterase Reactivators Attenuate Organophosphate-Induced Neuropathology in the Rat Hippocampus - Dail_2019_Toxicol.Sci_169_465
Author(s) : Dail MB , Leach CA , Meek EC , Olivier AK , Pringle RB , Green CE , Chambers JE
Ref : Toxicol Sci , 169 :465 , 2019
Abstract :
PubMedSearch : Dail_2019_Toxicol.Sci_169_465
PubMedID: 30835286

Title : In vitro P-glycoprotein activity does not completely explain in vivo efficacy of novel centrally effective oxime acetylcholinesterase reactivators - Dail_2018_Drug.Chem.Toxicol__1
Author(s) : Dail MB , Meek EC , Chambers HW , Chambers JE
Ref : Drug & Chemical Toxicology , :1 , 2018
Abstract :
PubMedSearch : Dail_2018_Drug.Chem.Toxicol__1
PubMedID: 29722548

Title : Neuroprotection From Organophosphate-Induced Damage by Novel Phenoxyalkyl Pyridinium Oximes in Rat Brain - Pringle_2018_Toxicol.Sci_166_420
Author(s) : Pringle RB , Meek EC , Chambers HW , Chambers JE
Ref : Toxicol Sci , 166 :420 , 2018
Abstract :
PubMedSearch : Pringle_2018_Toxicol.Sci_166_420
PubMedID: 30496567

Title : Effects of Chlorpyrifos or Methyl Parathion on Regional Cholinesterase Activity and Muscarinic Receptor Subtype Binding in Juvenile Rat Brain - Guo-Ross_2017_J.Toxicol.Pharmacol_1_
Author(s) : Guo-Ross SX , Meek EC , Chambers JE , Carr RL
Ref : J Toxicol Pharmacol , 1 : , 2017
Abstract :
PubMedSearch : Guo-Ross_2017_J.Toxicol.Pharmacol_1_
PubMedID: 30035273

Title : Novel brain-penetrating oximes for reactivation of cholinesterase inhibited by sarin and VX surrogates - Chambers_2016_Ann.N.Y.Acad.Sci_1374_52
Author(s) : Chambers JE , Meek EC , Chambers HW
Ref : Annals of the New York Academy of Sciences , 1374 :52 , 2016
Abstract :
PubMedSearch : Chambers_2016_Ann.N.Y.Acad.Sci_1374_52
PubMedID: 27153507

Title : Efficacy of novel phenoxyalkyl pyridinium oximes as brain-penetrating reactivators of cholinesterase inhibited by surrogates of sarin and VX - Chambers_2016_Chem.Biol.Interact_259_154
Author(s) : Chambers JE , Chambers HW , Funck KE , Meek EC , Pringle RB , Ross MK
Ref : Chemico-Biological Interactions , 259 :154 , 2016
Abstract :
PubMedSearch : Chambers_2016_Chem.Biol.Interact_259_154
PubMedID: 27387540

Title : The effect of PON1 enhancers on reducing acetylcholinesterase inhibition following organophosphate anticholinesterase exposure in rats - Meek_2015_Toxicology_336_79
Author(s) : Meek EC , Chambers HW , Pringle RB , Chambers JE
Ref : Toxicology , 336 :79 , 2015
Abstract :
PubMedSearch : Meek_2015_Toxicology_336_79
PubMedID: 26275814

Title : Novel substituted phenoxyalkyl pyridinium oximes enhance survival and attenuate seizure-like behavior of rats receiving lethal levels of nerve agent surrogates - Chambers_2015_Toxicology_339_51
Author(s) : Chambers JE , Meek EC , Bennett JP , Bennett WS , Chambers HW , Leach CA , Pringle RB , Wills RW
Ref : Toxicology , 339 :51 , 2015
Abstract :
PubMedSearch : Chambers_2015_Toxicology_339_51
PubMedID: 26705700

Title : Novel nucleophiles enhance the human serum paraoxonase 1 (PON1)-mediated detoxication of organophosphates - Chambers_2015_Toxicol.Sci_143_46
Author(s) : Chambers JE , Chambers HW , Meek EC , Funck KE , Bhavaraju MH , Gwaltney SR , Pringle RB
Ref : Toxicol Sci , 143 :46 , 2015
Abstract :
PubMedSearch : Chambers_2015_Toxicol.Sci_143_46
PubMedID: 25304213

Title : Testing of novel brain-penetrating oxime reactivators of acetylcholinesterase inhibited by nerve agent surrogates - Chambers_2013_Chem.Biol.Interact_203_135
Author(s) : Chambers JE , Chambers HW , Meek EC , Pringle RB
Ref : Chemico-Biological Interactions , 203 :135 , 2013
Abstract :
PubMedSearch : Chambers_2013_Chem.Biol.Interact_203_135
PubMedID: 23123249

Title : Synthesis and in vitro and in vivo inhibition potencies of highly relevant nerve agent surrogates - Meek_2012_Toxicol.Sci_126_525
Author(s) : Meek EC , Chambers HW , Coban A , Funck KE , Pringle RB , Ross MK , Chambers JE
Ref : Toxicol Sci , 126 :525 , 2012
Abstract :
PubMedSearch : Meek_2012_Toxicol.Sci_126_525
PubMedID: 22247004

Title : Altered muscarinic acetylcholine receptor subtype binding in neonatal rat brain following exposure to chlorpyrifos or methyl parathion - Guo-Ross_2007_Toxicol.Sci_100_118
Author(s) : Guo-Ross SX , Chambers JE , Meek EC , Carr RL
Ref : Toxicol Sci , 100 :118 , 2007
Abstract :
PubMedSearch : Guo-Ross_2007_Toxicol.Sci_100_118
PubMedID: 17666426

Title : Effects of PCB exposure on the toxic impact of organophosphorus insecticides - Carr_2002_Toxicol.Sci_67_311
Author(s) : Carr RL , Richardson JR , Guarisco JA , Kachroo A , Chambers JE , Couch TA , Durunna GC , Meek EC
Ref : Toxicol Sci , 67 :311 , 2002
Abstract :
PubMedSearch : Carr_2002_Toxicol.Sci_67_311
PubMedID: 12011491