Chambers JE

General

Full name : Chambers Janice E

First name : Janice E

Mail : Mississippi State University\; College of Veterinary Medicine\; Dept of Basic Sciences\; PO Box 6100\; College of Vet. Medicine\; 240 Wise Center Dr.\; Mississippi State University\; Mississippi\; 39762

Zip Code :

City :

Country : USA

Email : chambers@cvm.msstate.edu

Phone : +16623251255

Fax :

Website :

Directory :

References (55)

Title : Pharmacokinetics of three novel pyridinium aldoxime acetylcholinesterase reactivators in female rats - Backer_2022_Toxicol.Appl.Pharmacol_446_116046
Author(s) : Backer BS , Meek EC , Ross MK , Chambers JE
Ref : Toxicol Appl Pharmacol , 446 :116046 , 2022
PubMedID: 35550885

Title : Effect of high fat diet on the toxicokinetics and toxicodynamics of chlorpyrifos following acute exposure in male C57BL\/6J mice - Kondakala_2022_J.Biochem.Mol.Toxicol__e23028
Author(s) : Kondakala S , Ross MK , Chambers JE , Howell GE, 3rd
Ref : J Biochem Mol Toxicol , :e23028 , 2022
PubMedID: 35225412

Title : Effects of novel brain-penetrating oxime acetylcholinesterase reactivators on sarin surrogate-induced changes in rat brain gene expression - Dail_2021_J.Biochem.Mol.Toxicol__e22755
Author(s) : Dail ME , Brino MLM , Chambers JE
Ref : J Biochem Mol Toxicol , :e22755 , 2021
PubMedID: 33682265

Title : Reactivation of Organophosphate-inhibited Serum Butyrylcholinesterase by Novel Substituted Phenoxyalkyl Pyridinium Oximes and Traditional Oximes - Nichols_2021_Toxicology__152719
Author(s) : Nichols RH , Chambers JE
Ref : Toxicology , :152719 , 2021
PubMedID: 33592259

Title : Inhibition Kinetics of 16 Organophosphorus Pesticides or Their Active Metabolites on Erythrocyte Acetylcholinesterase from Humans and Rats - Meek_2021_Toxicol.Sci__
Author(s) : Meek EC , Reiss R , Crow JA , Chambers JE
Ref : Toxicol Sci , : , 2021
PubMedID: 33720374

Title : In vitro age-related differences in rats to organophosphates - Meek_2021_Toxicol.In.Vitro__105102
Author(s) : Meek EC , Carr RL , Chambers JE
Ref : Toxicol In Vitro , :105102 , 2021
PubMedID: 33497710

Title : Central neuroprotection demonstrated by novel oxime countermeasures to nerve agent surrogates - Chambers_2020_Ann.N.Y.Acad.Sci__
Author(s) : Chambers JE , Meek EC
Ref : Annals of the New York Academy of Sciences , : , 2020
PubMedID: 32319115

Title : Oxime-mediated reactivation of organophosphate-inhibited acetylcholinesterase with emphasis on centrally-active oximes - Chambers_2020_Neuropharmacol__108201
Author(s) : Chambers JE , Dail MB , Meek EC
Ref : Neuropharmacology , :108201 , 2020
PubMedID: 32544483

Title : Novel Brain-Penetrating Oxime Acetylcholinesterase Reactivators Attenuate Organophosphate-Induced Neuropathology in the Rat Hippocampus - Dail_2019_Toxicol.Sci_169_465
Author(s) : Dail MB , Leach CA , Meek EC , Olivier AK , Pringle RB , Green CE , Chambers JE
Ref : Toxicol Sci , 169 :465 , 2019
PubMedID: 30835286

Title : Novel centrally active oxime reactivators of acetylcholinesterase inhibited by surrogates of sarin and VX - Chambers_2019_Neurobiol.Dis__104487
Author(s) : Chambers JE , Meek EC
Ref : Neurobiol Dis , :104487 , 2019
PubMedID: 31158460

Title : In vitro P-glycoprotein activity does not completely explain in vivo efficacy of novel centrally effective oxime acetylcholinesterase reactivators - Dail_2018_Drug.Chem.Toxicol__1
Author(s) : Dail MB , Meek EC , Chambers HW , Chambers JE
Ref : Drug & Chemical Toxicology , :1 , 2018
PubMedID: 29722548

Title : Neuroprotection From Organophosphate-Induced Damage by Novel Phenoxyalkyl Pyridinium Oximes in Rat Brain - Pringle_2018_Toxicol.Sci_166_420
Author(s) : Pringle RB , Meek EC , Chambers HW , Chambers JE
Ref : Toxicol Sci , 166 :420 , 2018
PubMedID: 30496567

Title : Effects of Chlorpyrifos or Methyl Parathion on Regional Cholinesterase Activity and Muscarinic Receptor Subtype Binding in Juvenile Rat Brain - Guo-Ross_2017_J.Toxicol.Pharmacol_1_
Author(s) : Guo-Ross SX , Meek EC , Chambers JE , Carr RL
Ref : J Toxicol Pharmacol , 1 : , 2017
PubMedID: 30035273

Title : Efficacy of novel phenoxyalkyl pyridinium oximes as brain-penetrating reactivators of cholinesterase inhibited by surrogates of sarin and VX - Chambers_2016_Chem.Biol.Interact_259_154
Author(s) : Chambers JE , Chambers HW , Funck KE , Meek EC , Pringle RB , Ross MK
Ref : Chemico-Biological Interactions , 259 :154 , 2016
PubMedID: 27387540

Title : In vitro characterization of pralidoxime transport and acetylcholinesterase reactivation across MDCK cells and stem cell-derived human brain microvascular endothelial cells (BC1-hBMECs) - Gallagher_2016_Fluids.Barriers.CNS_13_10
Author(s) : Gallagher E , Minn I , Chambers JE , Searson PC
Ref : Fluids Barriers CNS , 13 :10 , 2016
PubMedID: 27396356

Title : Novel brain-penetrating oximes for reactivation of cholinesterase inhibited by sarin and VX surrogates - Chambers_2016_Ann.N.Y.Acad.Sci_1374_52
Author(s) : Chambers JE , Meek EC , Chambers HW
Ref : Annals of the New York Academy of Sciences , 1374 :52 , 2016
PubMedID: 27153507

Title : Comparison of inhibition kinetics of several organophosphates, including some nerve agent surrogates, using human erythrocyte and rat and mouse brain acetylcholinesterase - Coban_2016_Toxicol.Lett_248_39
Author(s) : Coban A , Carr RL , Chambers HW , Willeford KO , Chambers JE
Ref : Toxicol Lett , 248 :39 , 2016
PubMedID: 26965078

Title : Novel nucleophiles enhance the human serum paraoxonase 1 (PON1)-mediated detoxication of organophosphates - Chambers_2015_Toxicol.Sci_143_46
Author(s) : Chambers JE , Chambers HW , Meek EC , Funck KE , Bhavaraju MH , Gwaltney SR , Pringle RB
Ref : Toxicol Sci , 143 :46 , 2015
PubMedID: 25304213

Title : The effect of PON1 enhancers on reducing acetylcholinesterase inhibition following organophosphate anticholinesterase exposure in rats - Meek_2015_Toxicology_336_79
Author(s) : Meek EC , Chambers HW , Pringle RB , Chambers JE
Ref : Toxicology , 336 :79 , 2015
PubMedID: 26275814

Title : Novel substituted phenoxyalkyl pyridinium oximes enhance survival and attenuate seizure-like behavior of rats receiving lethal levels of nerve agent surrogates - Chambers_2015_Toxicology_339_51
Author(s) : Chambers JE , Meek EC , Bennett JP , Bennett WS , Chambers HW , Leach CA , Pringle RB , Wills RW
Ref : Toxicology , 339 :51 , 2015
PubMedID: 26705700

Title : Testing of novel brain-penetrating oxime reactivators of acetylcholinesterase inhibited by nerve agent surrogates - Chambers_2013_Chem.Biol.Interact_203_135
Author(s) : Chambers JE , Chambers HW , Meek EC , Pringle RB
Ref : Chemico-Biological Interactions , 203 :135 , 2013
PubMedID: 23123249

Title : Synthesis and in vitro and in vivo inhibition potencies of highly relevant nerve agent surrogates - Meek_2012_Toxicol.Sci_126_525
Author(s) : Meek EC , Chambers HW , Coban A , Funck KE , Pringle RB , Ross MK , Chambers JE
Ref : Toxicol Sci , 126 :525 , 2012
PubMedID: 22247004

Title : Developmental chlorpyrifos and methyl parathion exposure alters radial-arm maze performance in juvenile and adult rats - Johnson_2009_Toxicol.Sci_109_132
Author(s) : Johnson FO , Chambers JE , Nail CA , Givaruangsawat S , Carr RL
Ref : Toxicol Sci , 109 :132 , 2009
PubMedID: 19293373

Title : Assessing intermittent pesticide exposure from flea control collars containing the organophosphorus insecticide tetrachlorvinphos - Davis_2008_J.Expo.Sci.Environ.Epidemiol_18_564
Author(s) : Davis MK , Boone JS , Moran JE , Tyler JW , Chambers JE
Ref : J Expo Sci Environ Epidemiol , 18 :564 , 2008
PubMedID: 18167506

Title : Assessing transferable residues from intermittent exposure to flea control collars containing the organophosphate insecticide chlorpyrifos - Chambers_2007_J.Expo.Sci.Environ.Epidemiol_17_656
Author(s) : Chambers JE , Boone JS , Davis MK , Moran JE , Tyler JW
Ref : J Expo Sci Environ Epidemiol , 17 :656 , 2007
PubMedID: 17392689

Title : Altered muscarinic acetylcholine receptor subtype binding in neonatal rat brain following exposure to chlorpyrifos or methyl parathion - Guo-Ross_2007_Toxicol.Sci_100_118
Author(s) : Guo-Ross SX , Chambers JE , Meek EC , Carr RL
Ref : Toxicol Sci , 100 :118 , 2007
PubMedID: 17666426

Title : Effects of Piperonyl Butoxide on the Metabolism of DEF S,S,S-Tributyl Phosphorotrithioate) in Fingerling Channel Catfish - Straus_2006_Toxicol.Mech.Methods_16_235
Author(s) : Straus DL , Chambers JE
Ref : Toxicol Mech Methods , 16 :235 , 2006
PubMedID: 20021048

Title : Effects of topical phosmet on fur residue and cholinesterase activity of dogs - Boone_2006_Toxicol.Mech.Methods_16_275
Author(s) : Boone JS , Tyler JW , Davis MK , Chambers JE
Ref : Toxicol Mech Methods , 16 :275 , 2006
PubMedID: 20021025

Title : Effects of repeated oral postnatal exposure to chlorpyrifos on cholinergic neurochemistry in developing rats - Richardson_2005_Toxicol.Sci_84_352
Author(s) : Richardson JR , Chambers JE
Ref : Toxicol Sci , 84 :352 , 2005
PubMedID: 15647600

Title : Neurochemical effects of repeated gestational exposure to chlorpyrifos in developing rats - Richardson_2004_Toxicol.Sci_77_83
Author(s) : Richardson JR , Chambers JE
Ref : Toxicol Sci , 77 :83 , 2004
PubMedID: 14600274

Title : The effects of repeated oral exposures to methyl parathion on rat brain cholinesterase and muscarinic receptors during postnatal development - Tang_2003_Toxicol.Sci_76_400
Author(s) : Tang J , Carr RL , Chambers JE
Ref : Toxicol Sci , 76 :400 , 2003
PubMedID: 14514956

Title : Effects of gestational exposure to chlorpyrifos on postnatal central and peripheral cholinergic neurochemistry - Richardson_2003_J.Toxicol.Environ.Health.A_66_275
Author(s) : Richardson J , Chambers JE
Ref : J Toxicol Environ Health A , 66 :275 , 2003
PubMedID: 12521672

Title : Effects of PCB exposure on the toxic impact of organophosphorus insecticides - Carr_2002_Toxicol.Sci_67_311
Author(s) : Carr RL , Richardson JR , Guarisco JA , Kachroo A , Chambers JE , Couch TA , Durunna GC , Meek EC
Ref : Toxicol Sci , 67 :311 , 2002
PubMedID: 12011491

Title : Analysis of the additivity of in vitro inhibition of cholinesterase by mixtures of chlorpyrifos-oxon and azinphos-methyl-oxon - Richardson_2001_Toxicol.Appl.Pharmacol_172_128
Author(s) : Richardson JR , Chambers HW , Chambers JE
Ref : Toxicol Appl Pharmacol , 172 :128 , 2001
PubMedID: 11298499

Title : Transferable Residues From Dog Fur and Plasma Cholinesterase Inhibition in Dogs Treated with a Flea Control Dip Containing Chlorpyrifos - Boone_2001_Environ.Health.Perspect_109_1109
Author(s) : Boone JS , Tyler JW , Chambers JE
Ref : Environmental Health Perspectives , 109 :1109 , 2001
PubMedID: 11712994

Title : Effects of repeated oral postnatal exposure to chlorpyrifos on open-field behavior in juvenile rats - Carr_2001_Toxicol.Sci_59_260
Author(s) : Carr RL , Chambers HW , Guarisco JA , Richardson JR , Tang J , Chambers JE
Ref : Toxicol Sci , 59 :260 , 2001
PubMedID: 11158719

Title : Detoxication of paraoxon by rat liver homogenate and serum carboxylesterases and A-esterases - Tang_1999_J.Biochem.Mol.Toxicol_13_261
Author(s) : Tang J , Chambers JE
Ref : J Biochem Mol Toxicol , 13 :261 , 1999
PubMedID: 10402560

Title : Changes in rat brain cholinesterase activity and muscarinic receptor density during and after repeated oral exposure to chlorpyrifos in early postnatal development - Tang_1999_Toxicol.Sci_51_265
Author(s) : Tang J , Carr RL , Chambers JE
Ref : Toxicol Sci , 51 :265 , 1999
PubMedID: 10543028

Title : Common mechanism of toxicity: a case study of organophosphorus pesticides - Mileson_1998_Toxicol.Sci_41_8
Author(s) : Mileson BE , Chambers JE , Chen WL , Dettbarn W , Ehrich M , Eldefrawi AT , Gaylor DW , Hamernik K , Hodgson E , Karczmar AG , Padilla S , Pope CN , Richardson RJ , Saunders DR , Sheets LP , Sultatos LG , Wallace KB
Ref : Toxicol Sci , 41 :8 , 1998
PubMedID: 9520337

Title : Age-related differences in parathion and chlorpyrifos toxicity in male rats: target and nontarget esterase sensitivity and cytochrome P450- mediated metabolism - Atterberry_1997_Toxicol.Appl.Pharmacol_147_411
Author(s) : Atterberry TT , Burnett WT , Chambers JE
Ref : Toxicol Appl Pharmacol , 147 :411 , 1997
PubMedID: 9439736

Title : The effect of high and low dosages of paraoxon in beta-naphthoflavone-treated rats - Watson_1996_J.Biochem.Toxicol_11_263
Author(s) : Watson AM , Chambers JE
Ref : Journal of Biochemical Toxicology , 11 :263 , 1996
PubMedID: 9176738

Title : Time course of inhibition of cholinesterase and aliesterase activities, and nonprotein sulfhydryl levels following exposure to organophosphorus insecticides in mosquitofish (Gambusia affinis) - Boone_1996_Fundam.Appl.Toxicol_29_202
Author(s) : Boone JS , Chambers JE
Ref : Fundamental & Applied Toxicology , 29 :202 , 1996
PubMedID: 8742317

Title : Kinetic analysis of the in vitro inhibition, aging, and reactivation of brain acetylcholinesterase from rat and channel catfish by paraoxon and chlorpyrifos-oxon - Carr_1996_Toxicol.Appl.Pharmacol_139_365
Author(s) : Carr RL , Chambers JE
Ref : Toxicology & Applied Pharmacology , 139 :365 , 1996
PubMedID: 8806854

Title : Identification and isolation of two rat serum proteins with A-esterase activity toward paraoxon and chlorpyrifos-oxon - Pond_1996_Biochem.Pharmacol_52_363
Author(s) : Pond AL , Coyne CP , Chambers HW , Chambers JE
Ref : Biochemical Pharmacology , 52 :363 , 1996
PubMedID: 8694862

Title : Inhibition and aging of channel catfish brain acetylcholinesterase following exposure to two phosphorothionate insecticides and their active metabolites - Carr_1995_J.Toxicol.Env.Health_45_325
Author(s) : Carr RL , Straus DL , Chambers JE
Ref : Journal of Toxicology & Environmental Health , 45 :325 , 1995
PubMedID: 7541841

Title : Role of detoxication pathways in acute toxicity levels of phosphorothionate insecticides in the rat - Chambers_1994_Life.Sci_54_1357
Author(s) : Chambers JE , Ma T , Boone JS , Chambers HW
Ref : Life Sciences , 54 :1357 , 1994
PubMedID: 7514706

Title : Inhibition patterns of brain acetylcholinesterase and hepatic and plasma aliesterases following exposures to three phosphorothionate insecticides and their oxons in rats - Chambers_1993_Fundam.Appl.Toxicol_21_111
Author(s) : Chambers JE , Carr RL
Ref : Fundamental & Applied Toxicology , 21 :111 , 1993
PubMedID: 7689992

Title : Acute effects of the organophosphate paraoxon on schedule-controlled behavior and esterase activity in rats: dose-response relationships - Carr_1991_Pharmacol.Biochem.Behav_40_929
Author(s) : Carr RL , Chambers JE
Ref : Pharmacol Biochem Behav , 40 :929 , 1991
PubMedID: 1816579

Title : Noncatalytic detoxication of six organophosphorus compounds by rat liver homogenates - Chambers_1990_Pestic.Biochem.Physiol_36_308
Author(s) : Chambers HW , Brown B , Chambers JE
Ref : Pesticide Biochemistry and Physiology , 36 :308 , 1990
PubMedID:

Title : An investigation of acetylcholinesterase inhibition and aging and choline acetyltransferase activity following a high level acute exposure to paraoxon - Chambers_1989_Pestic.Biochem.Physiol_33_125
Author(s) : Chambers HW , Chambers JE
Ref : Pesticide Biochemistry and Physiology , 33 :125 , 1989
PubMedID:

Title : Short-term effects of paraoxon and atropine on schedule-controlled behavior in rats - Chambers_1989_Neurotoxicol.Teratol_11_427
Author(s) : Chambers JE , Chambers HW
Ref : Neurotoxicology & Teratology , 11 :427 , 1989
PubMedID: 2593981

Title : Effects of paraoxon, p-nitrophenol, phenyl saligenin cyclic phosphate, and phenol on the rat interleukin 2 system - Pruett_1988_Toxicol.Lett_40_11
Author(s) : Pruett SB , Chambers JE
Ref : Toxicol Lett , 40 :11 , 1988
PubMedID: 3257593

Title : The toxic and teratogenic effects of selected organophosphorus compounds on the embryos of three species of amphibians - Fulton_1985_Toxicol.Lett_26_175
Author(s) : Fulton MH , Chambers JE
Ref : Toxicol Lett , 26 :175 , 1985
PubMedID: 4035710

Title : Inhibition of neurotoxic esterase and acetylcholinesterase by organophosphorus compounds in selected ectothermic vertebrates - Fulton_1985_Pestic.Biochem.Physiol_23_282
Author(s) : Fulton MH , Chambers JE
Ref : Pesticide Biochemistry and Physiology , 23 :282 , 1985
PubMedID:

Title : Acute toxicities of selected herbicides to fingerling channel catfish, Ictalurus punctatus - McCorkle_1977_Bull.Environ.Contam.Toxicol_18_267
Author(s) : McCorkle FM , Chambers JE , Yarbrough JD
Ref : Bulletin of Environmental Contamination & Toxicology , 18 :267 , 1977
PubMedID: 907845