| Title : Ppt1-deficiency dysregulates lysosomal Ca(++) homeostasis contributing to pathogenesis in a mouse model of CLN1 disease - Mondal_2022_J.Inherit.Metab.Dis_45_635 |
| Author(s) : Mondal A , Appu AP , Sadhukhan T , Bagh MB , Previde RM , Sadhukhan S , Stojilkovic S , Liu A , Mukherjee AB |
| Ref : J Inherit Metab Dis , 45 :635 , 2022 |
| Abstract : |
| PubMedSearch : Mondal_2022_J.Inherit.Metab.Dis_45_635 |
| PubMedID: 35150145 |
| Gene_locus related to this paper: human-PPT1 , mouse-ppt |
| Title : In a mouse model of INCL reduced S-palmitoylation of cytosolic thioesterase APT1 contributes to microglia proliferation and neuroinflammation - Sadhukhan_2021_J.Inherit.Metab.Dis_44_1051 |
| Author(s) : Sadhukhan T , Bagh MB , Appu AP , Mondal A , Zhang W , Liu A , Mukherjee AB |
| Ref : J Inherit Metab Dis , 44 :1051 , 2021 |
| Abstract : |
| PubMedSearch : Sadhukhan_2021_J.Inherit.Metab.Dis_44_1051 |
| PubMedID: 33739454 |
| Gene_locus related to this paper: human-LYPLA1 , mouse-lypla1 |
| Title : Cln3-mutations underlying juvenile neuronal ceroid lipofuscinosis cause significantly reduced levels of Palmitoyl-protein thioesterases-1 (Ppt1)-protein and Ppt1-enzyme activity in the lysosome - Appu_2019_J.Inherit.Metab.Dis_42_944 |
| Author(s) : Appu AP , Bagh MB , Sadhukhan T , Mondal A , Casey S , Mukherjee AB |
| Ref : J Inherit Metab Dis , 42 :944 , 2019 |
| Abstract : |
| PubMedSearch : Appu_2019_J.Inherit.Metab.Dis_42_944 |
| PubMedID: 31025705 |
| Gene_locus related to this paper: human-PPT1 |
| Title : Misrouting of v-ATPase subunit V0a1 dysregulates lysosomal acidification in a neurodegenerative lysosomal storage disease model - Bagh_2017_Nat.Commun_8_14612 |
| Author(s) : Bagh MB , Peng S , Chandra G , Zhang Z , Singh SP , Pattabiraman N , Liu A , Mukherjee AB |
| Ref : Nat Commun , 8 :14612 , 2017 |
| Abstract : |
| PubMedSearch : Bagh_2017_Nat.Commun_8_14612 |
| PubMedID: 28266544 |
| Gene_locus related to this paper: human-PPT1 , mouse-ppt |
| Title : Cln1 gene disruption in mice reveals a common pathogenic link between two of the most lethal childhood neurodegenerative lysosomal storage disorders - Chandra_2015_Hum.Mol.Genet_24_5416 |
| Author(s) : Chandra G , Bagh MB , Peng S , Saha A , Sarkar C , Moralle M , Zhang Z , Mukherjee AB |
| Ref : Hum Mol Genet , 24 :5416 , 2015 |
| Abstract : |
| PubMedSearch : Chandra_2015_Hum.Mol.Genet_24_5416 |
| PubMedID: 26160911 |
| Gene_locus related to this paper: mouse-ppt |
| Title : Mice homozygous for c.451C>T mutation in Cln1 gene recapitulate INCL phenotype - Bouchelion_2014_Ann.Clin.Transl.Neurol_1_1006 |
| Author(s) : Bouchelion A , Zhang Z , Li Y , Qian H , Mukherjee AB |
| Ref : Ann Clin Transl Neurol , 1 :1006 , 2014 |
| Abstract : |
| PubMedSearch : Bouchelion_2014_Ann.Clin.Transl.Neurol_1_1006 |
| PubMedID: 25574475 |
| Gene_locus related to this paper: mouse-ppt |
| Title : Dynamic palmitoylation links cytosol-membrane shuttling of acyl-protein thioesterase-1 and acyl-protein thioesterase-2 with that of proto-oncogene H-ras product and growth-associated protein-43 - Kong_2013_J.Biol.Chem_288_9112 |
| Author(s) : Kong E , Peng S , Chandra G , Sarkar C , Zhang Z , Bagh MB , Mukherjee AB |
| Ref : Journal of Biological Chemistry , 288 :9112 , 2013 |
| Abstract : |
| PubMedSearch : Kong_2013_J.Biol.Chem_288_9112 |
| PubMedID: 23396970 |
| Title : Neuroprotection and lifespan extension in Ppt1(-\/-) mice by NtBuHA: therapeutic implications for INCL - Sarkar_2013_Nat.Neurosci_16_1608 |
| Author(s) : Sarkar C , Chandra G , Peng S , Zhang Z , Liu A , Mukherjee AB |
| Ref : Nat Neurosci , 16 :1608 , 2013 |
| Abstract : |
| PubMedSearch : Sarkar_2013_Nat.Neurosci_16_1608 |
| PubMedID: 24056696 |
| Gene_locus related to this paper: mouse-ppt |
| Title : In a model of Batten disease, palmitoyl protein thioesterase-1 deficiency is associated with brown adipose tissue and thermoregulation abnormalities - Khaibullina_2012_PLoS.One_7_e48733 |
| Author(s) : Khaibullina A , Kenyon N , Guptill V , Quezado MM , Wang L , Koziol D , Wesley R , Moya PR , Zhang Z , Saha A , Mukherjee AB , Quezado ZM |
| Ref : PLoS ONE , 7 :e48733 , 2012 |
| Abstract : |
| PubMedSearch : Khaibullina_2012_PLoS.One_7_e48733 |
| PubMedID: 23139814 |
| Gene_locus related to this paper: mouse-ppt |
| Title : Evaluation of neurodegeneration in a mouse model of infantile batten disease by magnetic resonance imaging and magnetic resonance spectroscopy - Munasinghe_2012_Neurodegener.Dis_9_159 |
| Author(s) : Munasinghe J , Zhang Z , Kong E , Heffer A , Mukherjee AB |
| Ref : Neurodegener Dis , 9 :159 , 2012 |
| Abstract : |
| PubMedSearch : Munasinghe_2012_Neurodegener.Dis_9_159 |
| PubMedID: 22327870 |
| Gene_locus related to this paper: mouse-ppt |
| Title : The blood-brain barrier is disrupted in a mouse model of infantile neuronal ceroid lipofuscinosis: amelioration by resveratrol - Saha_2012_Hum.Mol.Genet_21_2233 |
| Author(s) : Saha A , Sarkar C , Singh SP , Zhang Z , Munasinghe J , Peng S , Chandra G , Kong E , Mukherjee AB |
| Ref : Hum Mol Genet , 21 :2233 , 2012 |
| Abstract : |
| PubMedSearch : Saha_2012_Hum.Mol.Genet_21_2233 |
| PubMedID: 22331300 |
| Gene_locus related to this paper: mouse-ppt |
| Title : Omega-3 and omega-6 fatty acids suppress ER- and oxidative stress in cultured neurons and neuronal progenitor cells from mice lacking PPT1 - Kim_2010_Neurosci.Lett_479_292 |
| Author(s) : Kim SJ , Zhang Z , Saha A , Sarkar C , Zhao Z , Xu Y , Mukherjee AB |
| Ref : Neuroscience Letters , 479 :292 , 2010 |
| Abstract : |
| PubMedSearch : Kim_2010_Neurosci.Lett_479_292 |
| PubMedID: 20561933 |
| Gene_locus related to this paper: mouse-ppt |
| Title : ER and oxidative stresses are common mediators of apoptosis in both neurodegenerative and non-neurodegenerative lysosomal storage disorders and are alleviated by chemical chaperones - Wei_2008_Hum.Mol.Genet_17_469 |
| Author(s) : Wei H , Kim SJ , Zhang Z , Tsai PC , Wisniewski KE , Mukherjee AB |
| Ref : Hum Mol Genet , 17 :469 , 2008 |
| Abstract : |
| PubMedSearch : Wei_2008_Hum.Mol.Genet_17_469 |
| PubMedID: 17989065 |
| Title : Palmitoyl protein thioesterase-1 deficiency impairs synaptic vesicle recycling at nerve terminals, contributing to neuropathology in humans and mice - Kim_2008_J.Clin.Invest_118_3075 |
| Author(s) : Kim SJ , Zhang Z , Sarkar C , Tsai PC , Lee YC , Dye L , Mukherjee AB |
| Ref : J Clinical Investigation , 118 :3075 , 2008 |
| Abstract : |
| PubMedSearch : Kim_2008_J.Clin.Invest_118_3075 |
| PubMedID: 18704195 |
| Gene_locus related to this paper: mouse-ppt , human-PPT1 |
| Title : RAGE signaling contributes to neuroinflammation in infantile neuronal ceroid lipofuscinosis - Saha_2008_FEBS.Lett_582_3823 |
| Author(s) : Saha A , Kim SJ , Zhang Z , Lee YC , Sarkar C , Tsai PC , Mukherjee AB |
| Ref : FEBS Letters , 582 :3823 , 2008 |
| Abstract : |
| PubMedSearch : Saha_2008_FEBS.Lett_582_3823 |
| PubMedID: 18948101 |
| Gene_locus related to this paper: mouse-ppt , human-PPT1 |
| Title : Production of lysophosphatidylcholine by cPLA2 in the brain of mice lacking PPT1 is a signal for phagocyte infiltration - Zhang_2007_Hum.Mol.Genet_16_837 |
| Author(s) : Zhang Z , Lee YC , Kim SJ , Choi MS , Tsai PC , Saha A , Wei H , Xu Y , Xiao YJ , Zhang P , Heffer A , Mukherjee AB |
| Ref : Hum Mol Genet , 16 :837 , 2007 |
| Abstract : |
| PubMedSearch : Zhang_2007_Hum.Mol.Genet_16_837 |
| PubMedID: 17341491 |
| Gene_locus related to this paper: mouse-ppt |
| Title : Palmitoyl-protein thioesterase-1 deficiency mediates the activation of the unfolded protein response and neuronal apoptosis in INCL - Zhang_2006_Hum.Mol.Genet_15_337 |
| Author(s) : Zhang Z , Lee YC , Kim SJ , Choi MS , Tsai PC , Xu Y , Xiao YJ , Zhang P , Heffer A , Mukherjee AB |
| Ref : Hum Mol Genet , 15 :337 , 2006 |
| Abstract : |
| PubMedSearch : Zhang_2006_Hum.Mol.Genet_15_337 |
| PubMedID: 16368712 |
| Gene_locus related to this paper: mouse-ppt |
| Title : Endoplasmic reticulum stress-induced caspase-4 activation mediates apoptosis and neurodegeneration in INCL - Kim_2006_Hum.Mol.Genet_15_1826 |
| Author(s) : Kim SJ , Zhang Z , Hitomi E , Lee YC , Mukherjee AB |
| Ref : Hum Mol Genet , 15 :1826 , 2006 |
| Abstract : |
| PubMedSearch : Kim_2006_Hum.Mol.Genet_15_1826 |
| PubMedID: 16644870 |
| Gene_locus related to this paper: human-PPT1 |
| Title : Palmitoyl-protein thioesterase-1 deficiency leads to the activation of caspase-9 and contributes to rapid neurodegeneration in INCL - Kim_2006_Hum.Mol.Genet_15_1580 |
| Author(s) : Kim SJ , Zhang Z , Lee YC , Mukherjee AB |
| Ref : Hum Mol Genet , 15 :1580 , 2006 |
| Abstract : |
| PubMedSearch : Kim_2006_Hum.Mol.Genet_15_1580 |
| PubMedID: 16571600 |
| Gene_locus related to this paper: mouse-ppt |
| Title : Lysosomal ceroid depletion by drugs: therapeutic implications for a hereditary neurodegenerative disease of childhood - Zhang_2001_Nat.Med_7_478 |
| Author(s) : Zhang Z , Butler JD , Levin SW , Wisniewski KE , Brooks SS , Mukherjee AB |
| Ref : Nat Med , 7 :478 , 2001 |
| Abstract : |
| PubMedSearch : Zhang_2001_Nat.Med_7_478 |
| PubMedID: 11283676 |