Mus musculus (Mouse) palmitoyl-protein thioesterase PPT1 CLN1
some differences between Q9WTY3 Q9D681 O88531 || Palmitoyl-protein thioesterase (PPT1) is a small glycoprotein that removes palmitate groups from cysteine residues in lipid-modified proteins. PPT is thought to be involved in the catabolism of lipid-modified proteins (Camp et al., 1994).The genes PPT1 and CLN2 (607998), which are mutant in Infantile neuronal ceroid lipofuscinosis. Insensitive to commonly used serine-modifying reagents phenylmethylsulfonyl fluoride (PMSF) and diisopropylfluorophosphate. See paper of structure of bovine enzyme 1EXW (Das et al. 2000) NCL Mutation and Patient Database NCL<\/A>. Mutations in at least 13 different genes (called CLNs) underlie various forms of neuronal ceroid lipofuscinoses (NCLs), a group of the most common neurodegenerative lysosomal storage diseases. The CLN1 gene encodes palmitoyl-protein thioesterases-1 (PPT1). Mutations cause infantile NCL (INCL)
Family : Palmitoyl-protein_thioesterase
Block : X
Position in NCBI Life Tree : Mus musculus
(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.)
> cellular organisms N E > Eukaryota N E > Opisthokonta N E > Metazoa N E > Eumetazoa N E > Bilateria N E > Deuterostomia N E > Chordata N E > Craniata N E > Vertebrata N E > Gnathostomata N E > Teleostomi N E > Euteleostomi N E > Sarcopterygii N E > Dipnotetrapodomorpha N E > Tetrapoda N E > Amniota N E > Mammalia N E > Theria N E > Eutheria N E > Boreoeutheria N E > Euarchontoglires N E > Glires N E > Rodentia N E > Myomorpha N E > Muroidea N E > Muridae N E > Murinae N E > Mus [genus] N E > Mus [subgenus] N E > Mus musculus N EMMASSCSRRL LAAALLPWCC AAWALGHLDP PSPPPLVIWH GMGDSCCNPM SMGVIKKMVE KEIPGIYVLS LEIGKNMMED VENSFFLNVN VQVNMVCQIL EKDPKLQQGY NAIGFSQGGQ FLRAVAQRCP TPPMMTLISV GGQHQGVFGL PRCPGESSHI CDFIRKSLNA GAYSKLVQER LVQAQYWHDP IKESVYRNYS IFLADINQER CVNESYKKNL MALKKFVMVK FFNDSIVDPV DSEWFGFYRS GQAKETIPLQ ESTLYTEDRL GLKKMDKAGK LVFLAKEGDH LQISKEWFTA HIIPFLK
| Title : Ppt1-deficiency dysregulates lysosomal Ca(++) homeostasis contributing to pathogenesis in a mouse model of CLN1 disease - Mondal_2022_J.Inherit.Metab.Dis_45_635 |
| Author(s) : Mondal A , Appu AP , Sadhukhan T , Bagh MB , Previde RM , Sadhukhan S , Stojilkovic S , Liu A , Mukherjee AB |
| Ref : J Inherit Metab Dis , 45 :635 , 2022 |
| Abstract : |
| PubMedSearch : Mondal_2022_J.Inherit.Metab.Dis_45_635 |
| PubMedID: 35150145 |
| Gene_locus related to this paper: human-PPT1 , mouse-ppt |
| Title : GFAP hyperpalmitoylation exacerbates astrogliosis and neurodegenerative pathology in PPT1-deficient mice - Yuan_2021_Proc.Natl.Acad.Sci.U.S.A_118_e2022261118 |
| Author(s) : Yuan W , Lu L , Rao M , Huang Y , Liu CE , Liu S , Zhao Y , Liu H , Zhu J , Chao T , Wu C , Ren J , Lv L , Li W , Qi S , Liang Y , Yue S , Gao J , Zhang Z , Kong E |
| Ref : Proc Natl Acad Sci U S A , 118 : , 2021 |
| Abstract : |
| PubMedSearch : Yuan_2021_Proc.Natl.Acad.Sci.U.S.A_118_e2022261118 |
| PubMedID: 33753498 |
| Gene_locus related to this paper: mouse-ppt |
| Title : Thioesterase PPT1 balances viral resistance and efficient T cell crosspriming in dendritic cells - Ou_2019_J.Exp.Med_216_2091 |
| Author(s) : Ou P , Wen L , Liu X , Huang J , Huang X , Su C , Wang L , Ni H , Reizis B , Yang CY |
| Ref : J Exp Med , 216 :2091 , 2019 |
| Abstract : |
| PubMedSearch : Ou_2019_J.Exp.Med_216_2091 |
| PubMedID: 31262842 |
| Gene_locus related to this paper: human-PPT1 , mouse-ppt |
| Title : Misrouting of v-ATPase subunit V0a1 dysregulates lysosomal acidification in a neurodegenerative lysosomal storage disease model - Bagh_2017_Nat.Commun_8_14612 |
| Author(s) : Bagh MB , Peng S , Chandra G , Zhang Z , Singh SP , Pattabiraman N , Liu A , Mukherjee AB |
| Ref : Nat Commun , 8 :14612 , 2017 |
| Abstract : |
| PubMedSearch : Bagh_2017_Nat.Commun_8_14612 |
| PubMedID: 28266544 |
| Gene_locus related to this paper: human-PPT1 , mouse-ppt |
| Title : Fingolimod and Teriflunomide Attenuate Neurodegeneration in Mouse Models of Neuronal Ceroid Lipofuscinosis - Groh_2017_Mol.Ther_25_1889 |
| Author(s) : Groh J , Berve K , Martini R |
| Ref : Mol Ther , 25 :1889 , 2017 |
| Abstract : |
| PubMedSearch : Groh_2017_Mol.Ther_25_1889 |
| PubMedID: 28506594 |
| Gene_locus related to this paper: mouse-ppt |
| Title : Synergistic effects of treating the spinal cord and brain in CLN1 disease - Shyng_2017_Proc.Natl.Acad.Sci.U.S.A_114_E5920 |
| Author(s) : Shyng C , Nelvagal HR , Dearborn JT , Tyynela J , Schmidt RE , Sands MS , Cooper JD |
| Ref : Proc Natl Acad Sci U S A , 114 :E5920 , 2017 |
| Abstract : |
| PubMedSearch : Shyng_2017_Proc.Natl.Acad.Sci.U.S.A_114_E5920 |
| PubMedID: 28673981 |
| Gene_locus related to this paper: mouse-ppt |
| Title : Sialoadhesin promotes neuroinflammation-related disease progression in two mouse models of CLN disease - Groh_2016_Glia_64_792 |
| Author(s) : Groh J , Ribechini E , Stadler D , Schilling T , Lutz MB , Martini R |
| Ref : Glia , 64 :792 , 2016 |
| Abstract : |
| PubMedSearch : Groh_2016_Glia_64_792 |
| PubMedID: 26775238 |
| Gene_locus related to this paper: mouse-ppt |
| Title : Tissue-specific variation in nonsense mutant transcript level and drug-induced read-through efficiency in the Cln1(R151X) mouse model of INCL - Thada_2016_J.Cell.Mol.Med_20_381 |
| Author(s) : Thada V , Miller JN , Kovacs AD , Pearce DA |
| Ref : J Cell Mol Med , 20 :381 , 2016 |
| Abstract : |
| PubMedSearch : Thada_2016_J.Cell.Mol.Med_20_381 |
| PubMedID: 26648046 |
| Gene_locus related to this paper: mouse-ppt |
| Title : Cln1 gene disruption in mice reveals a common pathogenic link between two of the most lethal childhood neurodegenerative lysosomal storage disorders - Chandra_2015_Hum.Mol.Genet_24_5416 |
| Author(s) : Chandra G , Bagh MB , Peng S , Saha A , Sarkar C , Moralle M , Zhang Z , Mukherjee AB |
| Ref : Hum Mol Genet , 24 :5416 , 2015 |
| Abstract : |
| PubMedSearch : Chandra_2015_Hum.Mol.Genet_24_5416 |
| PubMedID: 26160911 |
| Gene_locus related to this paper: mouse-ppt |
| Title : Comprehensive functional characterization of murine infantile Batten disease including Parkinson-like behavior and dopaminergic markers - Dearborn_2015_Sci.Rep_5_12752 |
| Author(s) : Dearborn JT , Harmon SK , Fowler SC , O'Malley KL , Taylor GT , Sands MS , Wozniak DF |
| Ref : Sci Rep , 5 :12752 , 2015 |
| Abstract : |
| PubMedSearch : Dearborn_2015_Sci.Rep_5_12752 |
| PubMedID: 26238334 |
| Gene_locus related to this paper: mouse-ppt |
| Title : Intrathecal enzyme replacement therapy improves motor function and survival in a preclinical mouse model of infantile neuronal ceroid lipofuscinosis - Lu_2015_Mol.Genet.Metab_116_98 |
| Author(s) : Lu JY , Nelvagal HR , Wang L , Birnbaum SG , Cooper JD , Hofmann SL |
| Ref : Mol Genet Metab , 116 :98 , 2015 |
| Abstract : |
| PubMedSearch : Lu_2015_Mol.Genet.Metab_116_98 |
| PubMedID: 25982063 |
| Gene_locus related to this paper: mouse-ppt |
| Title : Mice homozygous for c.451C>T mutation in Cln1 gene recapitulate INCL phenotype - Bouchelion_2014_Ann.Clin.Transl.Neurol_1_1006 |
| Author(s) : Bouchelion A , Zhang Z , Li Y , Qian H , Mukherjee AB |
| Ref : Ann Clin Transl Neurol , 1 :1006 , 2014 |
| Abstract : |
| PubMedSearch : Bouchelion_2014_Ann.Clin.Transl.Neurol_1_1006 |
| PubMedID: 25574475 |
| Gene_locus related to this paper: mouse-ppt |
| Title : Treatment of the Ppt1(-\/-) mouse model of infantile neuronal ceroid lipofuscinosis with the N-methyl-D-aspartate (NMDA) receptor antagonist memantine - Finn_2013_J.Child.Neurol_28_1159 |
| Author(s) : Finn R , Kovacs AD , Pearce DA |
| Ref : Journal of Child Neurology , 28 :1159 , 2013 |
| Abstract : |
| PubMedSearch : Finn_2013_J.Child.Neurol_28_1159 |
| PubMedID: 24014511 |
| Gene_locus related to this paper: mouse-ppt |
| Title : Neuroprotection and lifespan extension in Ppt1(-\/-) mice by NtBuHA: therapeutic implications for INCL - Sarkar_2013_Nat.Neurosci_16_1608 |
| Author(s) : Sarkar C , Chandra G , Peng S , Zhang Z , Liu A , Mukherjee AB |
| Ref : Nat Neurosci , 16 :1608 , 2013 |
| Abstract : |
| PubMedSearch : Sarkar_2013_Nat.Neurosci_16_1608 |
| PubMedID: 24056696 |
| Gene_locus related to this paper: mouse-ppt |
| Title : Altered glutamate receptor function in the cerebellum of the Ppt1-\/- mouse, a murine model of infantile neuronal ceroid lipofuscinosis - Finn_2012_J.Neurosci.Res_90_367 |
| Author(s) : Finn R , Kovacs AD , Pearce DA |
| Ref : Journal of Neuroscience Research , 90 :367 , 2012 |
| Abstract : |
| PubMedSearch : Finn_2012_J.Neurosci.Res_90_367 |
| PubMedID: 21971706 |
| Gene_locus related to this paper: mouse-ppt |
| Title : Intravenous high-dose enzyme replacement therapy with recombinant palmitoyl-protein thioesterase reduces visceral lysosomal storage and modestly prolongs survival in a preclinical mouse model of infantile neuronal ceroid lipofuscinosis - Hu_2012_Mol.Genet.Metab_107_213 |
| Author(s) : Hu J , Lu JY , Wong AM , Hynan LS , Birnbaum SG , Yilmaz DS , Streit BM , Lenartowicz EM , Thompson TC , Cooper JD , Hofmann SL |
| Ref : Mol Genet Metab , 107 :213 , 2012 |
| Abstract : |
| PubMedSearch : Hu_2012_Mol.Genet.Metab_107_213 |
| PubMedID: 22704978 |
| Gene_locus related to this paper: mouse-ppt |
| Title : In a model of Batten disease, palmitoyl protein thioesterase-1 deficiency is associated with brown adipose tissue and thermoregulation abnormalities - Khaibullina_2012_PLoS.One_7_e48733 |
| Author(s) : Khaibullina A , Kenyon N , Guptill V , Quezado MM , Wang L , Koziol D , Wesley R , Moya PR , Zhang Z , Saha A , Mukherjee AB , Quezado ZM |
| Ref : PLoS ONE , 7 :e48733 , 2012 |
| Abstract : |
| PubMedSearch : Khaibullina_2012_PLoS.One_7_e48733 |
| PubMedID: 23139814 |
| Gene_locus related to this paper: mouse-ppt |
| Title : Synergistic effects of central nervous system-directed gene therapy and bone marrow transplantation in the murine model of infantile neuronal ceroid lipofuscinosis - Macauley_2012_Ann.Neurol_71_797 |
| Author(s) : Macauley SL , Roberts MS , Wong AM , McSloy F , Reddy AS , Cooper JD , Sands MS |
| Ref : Annals of Neurology , 71 :797 , 2012 |
| Abstract : |
| PubMedSearch : Macauley_2012_Ann.Neurol_71_797 |
| PubMedID: 22368049 |
| Gene_locus related to this paper: mouse-ppt |
| Title : Evaluation of neurodegeneration in a mouse model of infantile batten disease by magnetic resonance imaging and magnetic resonance spectroscopy - Munasinghe_2012_Neurodegener.Dis_9_159 |
| Author(s) : Munasinghe J , Zhang Z , Kong E , Heffer A , Mukherjee AB |
| Ref : Neurodegener Dis , 9 :159 , 2012 |
| Abstract : |
| PubMedSearch : Munasinghe_2012_Neurodegener.Dis_9_159 |
| PubMedID: 22327870 |
| Gene_locus related to this paper: mouse-ppt |
| Title : Combination small molecule PPT1 mimetic and CNS-directed gene therapy as a treatment for infantile neuronal ceroid lipofuscinosis - Roberts_2012_J.Inherit.Metab.Dis_35_847 |
| Author(s) : Roberts MS , Macauley SL , Wong AM , Yilmas D , Hohm S , Cooper JD , Sands MS |
| Ref : J Inherit Metab Dis , 35 :847 , 2012 |
| Abstract : |
| PubMedSearch : Roberts_2012_J.Inherit.Metab.Dis_35_847 |
| PubMedID: 22310926 |
| Gene_locus related to this paper: mouse-ppt |
| Title : The blood-brain barrier is disrupted in a mouse model of infantile neuronal ceroid lipofuscinosis: amelioration by resveratrol - Saha_2012_Hum.Mol.Genet_21_2233 |
| Author(s) : Saha A , Sarkar C , Singh SP , Zhang Z , Munasinghe J , Peng S , Chandra G , Kong E , Mukherjee AB |
| Ref : Hum Mol Genet , 21 :2233 , 2012 |
| Abstract : |
| PubMedSearch : Saha_2012_Hum.Mol.Genet_21_2233 |
| PubMedID: 22331300 |
| Gene_locus related to this paper: mouse-ppt |
| Title : Mouse models of neuronal ceroid lipofuscinoses: useful pre-clinical tools to delineate disease pathophysiology and validate therapeutics - Shacka_2012_Brain.Res.Bull_88_43 |
| Author(s) : Shacka JJ |
| Ref : Brain Research Bulletin , 88 :43 , 2012 |
| Abstract : |
| PubMedSearch : Shacka_2012_Brain.Res.Bull_88_43 |
| PubMedID: 22502604 |
| Gene_locus related to this paper: mouse-ppt |
| Title : The role of attenuated astrocyte activation in infantile neuronal ceroid lipofuscinosis - Macauley_2011_J.Neurosci_31_15575 |
| Author(s) : Macauley SL , Pekny M , Sands MS |
| Ref : Journal of Neuroscience , 31 :15575 , 2011 |
| Abstract : |
| PubMedSearch : Macauley_2011_J.Neurosci_31_15575 |
| PubMedID: 22031903 |
| Gene_locus related to this paper: mouse-ppt |
| Title : Omega-3 and omega-6 fatty acids suppress ER- and oxidative stress in cultured neurons and neuronal progenitor cells from mice lacking PPT1 - Kim_2010_Neurosci.Lett_479_292 |
| Author(s) : Kim SJ , Zhang Z , Saha A , Sarkar C , Zhao Z , Xu Y , Mukherjee AB |
| Ref : Neuroscience Letters , 479 :292 , 2010 |
| Abstract : |
| PubMedSearch : Kim_2010_Neurosci.Lett_479_292 |
| PubMedID: 20561933 |
| Gene_locus related to this paper: mouse-ppt |
| Title : Human recombinant palmitoyl-protein thioesterase-1 (PPT1) for preclinical evaluation of enzyme replacement therapy for infantile neuronal ceroid lipofuscinosis - Lu_2010_Mol.Genet.Metab_99_374 |
| Author(s) : Lu JY , Hu J , Hofmann SL |
| Ref : Mol Genet Metab , 99 :374 , 2010 |
| Abstract : |
| PubMedSearch : Lu_2010_Mol.Genet.Metab_99_374 |
| PubMedID: 20036592 |
| Gene_locus related to this paper: mouse-ppt |
| Title : Molecular correlates of axonal and synaptic pathology in mouse models of Batten disease - Kielar_2009_Hum.Mol.Genet_18_4066 |
| Author(s) : Kielar C , Wishart TM , Palmer A , Dihanich S , Wong AM , Macauley SL , Chan CH , Sands MS , Pearce DA , Cooper JD , Gillingwater TH |
| Ref : Hum Mol Genet , 18 :4066 , 2009 |
| Abstract : |
| PubMedSearch : Kielar_2009_Hum.Mol.Genet_18_4066 |
| PubMedID: 19640925 |
| Gene_locus related to this paper: mouse-ppt |
| Title : Cerebellar pathology and motor deficits in the palmitoyl protein thioesterase 1-deficient mouse - Macauley_2009_Exp.Neurol_217_124 |
| Author(s) : Macauley SL , Wozniak DF , Kielar C , Tan Y , Cooper JD , Sands MS |
| Ref : Experimental Neurology , 217 :124 , 2009 |
| Abstract : |
| PubMedSearch : Macauley_2009_Exp.Neurol_217_124 |
| PubMedID: 19416667 |
| Gene_locus related to this paper: mouse-ppt |
| Title : A murine model of infantile neuronal ceroid lipofuscinosis-ultrastructural evaluation of storage in the central nervous system and viscera - Galvin_2008_Pediatr.Dev.Pathol_11_185 |
| Author(s) : Galvin N , Vogler C , Levy B , Kovacs A , Griffey M , Sands MS |
| Ref : Pediatr Dev Pathol , 11 :185 , 2008 |
| Abstract : |
| PubMedSearch : Galvin_2008_Pediatr.Dev.Pathol_11_185 |
| PubMedID: 17990914 |
| Gene_locus related to this paper: mouse-ppt |
| Title : Palmitoyl protein thioesterase-1 deficiency impairs synaptic vesicle recycling at nerve terminals, contributing to neuropathology in humans and mice - Kim_2008_J.Clin.Invest_118_3075 |
| Author(s) : Kim SJ , Zhang Z , Sarkar C , Tsai PC , Lee YC , Dye L , Mukherjee AB |
| Ref : J Clinical Investigation , 118 :3075 , 2008 |
| Abstract : |
| PubMedSearch : Kim_2008_J.Clin.Invest_118_3075 |
| PubMedID: 18704195 |
| Gene_locus related to this paper: mouse-ppt , human-PPT1 |
| Title : Deficiency of the INCL protein Ppt1 results in changes in ectopic F1-ATP synthase and altered cholesterol metabolism - Lyly_2008_Hum.Mol.Genet_17_1406 |
| Author(s) : Lyly A , Marjavaara SK , Kyttala A , Uusi-Rauva K , Luiro K , Kopra O , Martinez LO , Tanhuanpaa K , Kalkkinen N , Suomalainen A , Jauhiainen M , Jalanko A |
| Ref : Hum Mol Genet , 17 :1406 , 2008 |
| Abstract : |
| PubMedSearch : Lyly_2008_Hum.Mol.Genet_17_1406 |
| PubMedID: 18245779 |
| Gene_locus related to this paper: mouse-ppt |
| Title : RAGE signaling contributes to neuroinflammation in infantile neuronal ceroid lipofuscinosis - Saha_2008_FEBS.Lett_582_3823 |
| Author(s) : Saha A , Kim SJ , Zhang Z , Lee YC , Sarkar C , Tsai PC , Mukherjee AB |
| Ref : FEBS Letters , 582 :3823 , 2008 |
| Abstract : |
| PubMedSearch : Saha_2008_FEBS.Lett_582_3823 |
| PubMedID: 18948101 |
| Gene_locus related to this paper: mouse-ppt , human-PPT1 |
| Title : Palmitoyl protein thioesterase 1 (Ppt1)-deficient mouse neurons show alterations in cholesterol metabolism and calcium homeostasis prior to synaptic dysfunction - Ahtiainen_2007_Neurobiol.Dis_28_52 |
| Author(s) : Ahtiainen L , Kolikova J , Mutka AL , Luiro K , Gentile M , Ikonen E , Khiroug L , Jalanko A , Kopra O |
| Ref : Neurobiol Dis , 28 :52 , 2007 |
| Abstract : |
| PubMedSearch : Ahtiainen_2007_Neurobiol.Dis_28_52 |
| PubMedID: 17656100 |
| Gene_locus related to this paper: mouse-ppt |
| Title : Glycosylation, transport, and complex formation of palmitoyl protein thioesterase 1 (PPT1)--distinct characteristics in neurons - Lyly_2007_BMC.Cell.Biol_8_22 |
| Author(s) : Lyly A , von Schantz C , Salonen T , Kopra O , Saarela J , Jauhiainen M , Kyttala A , Jalanko A |
| Ref : BMC Cell Biol , 8 :22 , 2007 |
| Abstract : |
| PubMedSearch : Lyly_2007_BMC.Cell.Biol_8_22 |
| PubMedID: 17565660 |
| Gene_locus related to this paper: mouse-ppt |
| Title : Gene expression profiling in a mouse model of infantile neuronal ceroid lipofuscinosis reveals upregulation of immediate early genes and mediators of the inflammatory response - Qiao_2007_BMC.Neurosci_8_95 |
| Author(s) : Qiao X , Lu JY , Hofmann SL |
| Ref : BMC Neurosci , 8 :95 , 2007 |
| Abstract : |
| PubMedSearch : Qiao_2007_BMC.Neurosci_8_95 |
| PubMedID: 18021406 |
| Gene_locus related to this paper: mouse-ppt |
| Title : Production of lysophosphatidylcholine by cPLA2 in the brain of mice lacking PPT1 is a signal for phagocyte infiltration - Zhang_2007_Hum.Mol.Genet_16_837 |
| Author(s) : Zhang Z , Lee YC , Kim SJ , Choi MS , Tsai PC , Saha A , Wei H , Xu Y , Xiao YJ , Zhang P , Heffer A , Mukherjee AB |
| Ref : Hum Mol Genet , 16 :837 , 2007 |
| Abstract : |
| PubMedSearch : Zhang_2007_Hum.Mol.Genet_16_837 |
| PubMedID: 17341491 |
| Gene_locus related to this paper: mouse-ppt |
| Title : Palmitoyl protein thioesterase 1 (PPT1) deficiency causes endocytic defects connected to abnormal saposin processing - Ahtiainen_2006_Exp.Cell.Res_312_1540 |
| Author(s) : Ahtiainen L , Luiro K , Kauppi M , Tyynela J , Kopra O , Jalanko A |
| Ref : Experimental Cell Research , 312 :1540 , 2006 |
| Abstract : |
| PubMedSearch : Ahtiainen_2006_Exp.Cell.Res_312_1540 |
| PubMedID: 16542649 |
| Gene_locus related to this paper: mouse-ppt |
| Title : Palmitoyl-protein thioesterase-1 deficiency leads to the activation of caspase-9 and contributes to rapid neurodegeneration in INCL - Kim_2006_Hum.Mol.Genet_15_1580 |
| Author(s) : Kim SJ , Zhang Z , Lee YC , Mukherjee AB |
| Ref : Hum Mol Genet , 15 :1580 , 2006 |
| Abstract : |
| PubMedSearch : Kim_2006_Hum.Mol.Genet_15_1580 |
| PubMedID: 16571600 |
| Gene_locus related to this paper: mouse-ppt |
| Title : Palmitoyl-protein thioesterase-1 deficiency mediates the activation of the unfolded protein response and neuronal apoptosis in INCL - Zhang_2006_Hum.Mol.Genet_15_337 |
| Author(s) : Zhang Z , Lee YC , Kim SJ , Choi MS , Tsai PC , Xu Y , Xiao YJ , Zhang P , Heffer A , Mukherjee AB |
| Ref : Hum Mol Genet , 15 :337 , 2006 |
| Abstract : |
| PubMedSearch : Zhang_2006_Hum.Mol.Genet_15_337 |
| PubMedID: 16368712 |
| Gene_locus related to this paper: mouse-ppt |
| Title : AAV2-mediated ocular gene therapy for infantile neuronal ceroid lipofuscinosis - Griffey_2005_Mol.Ther_12_413 |
| Author(s) : Griffey M , Macauley SL , Ogilvie JM , Sands MS |
| Ref : Mol Ther , 12 :413 , 2005 |
| Abstract : |
| PubMedSearch : Griffey_2005_Mol.Ther_12_413 |
| PubMedID: 15979943 |
| Gene_locus related to this paper: mouse-ppt |
| Title : Mice with Ppt1Deltaex4 mutation replicate the INCL phenotype and show an inflammation-associated loss of interneurons - Jalanko_2005_Neurobiol.Dis_18_226 |
| Author(s) : Jalanko A , Vesa J , Manninen T , von Schantz C , Minye H , Fabritius AL , Salonen T , Rapola J , Gentile M , Kopra O , Peltonen L |
| Ref : Neurobiol Dis , 18 :226 , 2005 |
| Abstract : |
| PubMedSearch : Jalanko_2005_Neurobiol.Dis_18_226 |
| PubMedID: 15649713 |
| Gene_locus related to this paper: mouse-ppt |
| Title : Progressively reduced synaptic vesicle pool size in cultured neurons derived from neuronal ceroid lipofuscinosis-1 knockout mice - Virmani_2005_Neurobiol.Dis_20_314 |
| Author(s) : Virmani T , Gupta P , Liu X , Kavalali ET , Hofmann SL |
| Ref : Neurobiol Dis , 20 :314 , 2005 |
| Abstract : |
| PubMedSearch : Virmani_2005_Neurobiol.Dis_20_314 |
| PubMedID: 16242638 |
| Gene_locus related to this paper: mouse-ppt |
| Title : Pre-sertoli specific gene expression profiling reveals differential expression of Ppt1 and Brd3 genes within the mouse genital ridge at the time of sex determination - Boyer_2004_Biol.Reprod_71_820 |
| Author(s) : Boyer A , Lussier JG , Sinclair AH , McClive PJ , Silversides DW |
| Ref : Biol Reprod , 71 :820 , 2004 |
| Abstract : |
| PubMedSearch : Boyer_2004_Biol.Reprod_71_820 |
| PubMedID: 15128596 |
| Gene_locus related to this paper: mouse-ppt |
| Title : Early changes in gene expression in two models of Batten disease - Elshatory_2003_FEBS.Lett_538_207 |
| Author(s) : Elshatory Y , Brooks AI , Chattopadhyay S , Curran TM , Gupta P , Ramalingam V , Hofmann SL , Pearce DA |
| Ref : FEBS Letters , 538 :207 , 2003 |
| Abstract : |
| PubMedSearch : Elshatory_2003_FEBS.Lett_538_207 |
| PubMedID: 12633880 |
| Gene_locus related to this paper: mouse-ppt |
| Title : Disruption of PPT1 or PPT2 causes neuronal ceroid lipofuscinosis in knockout mice - Gupta_2001_Proc.Natl.Acad.Sci.U.S.A_98_13566 |
| Author(s) : Gupta P , Soyombo AA , Atashband A , Wisniewski KE , Shelton JM , Richardson JA , Hammer RE , Hofmann SL |
| Ref : Proc Natl Acad Sci U S A , 98 :13566 , 2001 |
| Abstract : |
| PubMedSearch : Gupta_2001_Proc.Natl.Acad.Sci.U.S.A_98_13566 |
| PubMedID: 11717424 |
| Gene_locus related to this paper: mouse-ppt , mouse-PPT2 , human-PPT1 |
| Title : Mouse palmitoyl protein thioesterase: gene structure and expression of cDNA - Salonen_1998_Genome.Res_8_724 |
| Author(s) : Salonen T , Hellsten E , Horelli-Kuitunen N , Peltonen L , Jalanko A |
| Ref : Genome Res , 8 :724 , 1998 |
| Abstract : |
| PubMedSearch : Salonen_1998_Genome.Res_8_724 |
| PubMedID: 9685319 |
| Gene_locus related to this paper: mouse-ppt |