| Title : ABHD11 inhibition drives sterol metabolism to modulate T cell effector function and alleviate autoimmunity - Jenkins_2025_bioRxiv__ |
| Author(s) : Jenkins BJ , Jenkins YR , Ponce-Garcia FM , Moscrop C , Perry IA , Hitchings MD , Uribe AH , Bernuzzi F , Eastham S , Cronin JG , Berisha A , Howell A , Davies J , Blagih J , Veale DJ , Davies LC , Niphakis M , Finlay DK , Sinclair LV , Cravatt BF , Hogan AE , Nathan JA , Fearon U , Sumpton D , Vande Voorde J , Dias do Vale G , McDonald JG , Jones GW , Pearson JA , Vincent EE , Jones N |
| Ref : bioRxiv , : , 2025 |
| Abstract : |
| PubMedSearch : Jenkins_2025_bioRxiv__ |
| PubMedID: 40166327 |
| Gene_locus related to this paper: human-ABHD11 , mouse-Abhd11 |
| Title : Mitochondrial ABHD11 inhibition drives sterol metabolism to modulate T-cell effector function - Jenkins_2025_Nat.Commun_16_9484 |
| Author(s) : Jenkins BJ , Jenkins YR , Ponce-Garcia FM , Moscrop C , Perry IA , Hitchings MD , Uribe AH , Bernuzzi F , Eastham S , Cronin JG , Berisha A , Howell A , Davies J , Blagih J , Williams M , Marsden M , Veale DJ , Davies LC , Niphakis M , Finlay DK , Sinclair LV , Cravatt BF , Hogan AE , Nathan JA , Humphreys IR , Fearon U , Sumpton D , Vande Voorde J , Vale GDD , McDonald JG , Jones GW , Pearson JA , Vincent EE , Jones N |
| Ref : Nat Commun , 16 :9484 , 2025 |
| Abstract : |
| PubMedSearch : Jenkins_2025_Nat.Commun_16_9484 |
| PubMedID: 41184294 |
| Gene_locus related to this paper: human-ABHD11 , mouse-Abhd11 |
| Title : Lipoyl deglutarylation by ABHD11 regulates mitochondrial and T cell metabolism - Grice_2025_Nat.Chem.Biol__ |
| Author(s) : Grice GL , Minogue E , Coates HW , Debela M , Stopforth RJ , Wit N , Li Z , Crowley JP , Kaser A , Kaneider-Kaser N , Antrobus PR , Haigis MC , Johnson RS , Nathan JA |
| Ref : Nat Chemical Biology , : , 2025 |
| Abstract : |
| PubMedSearch : Grice_2025_Nat.Chem.Biol__ |
| PubMedID: 40664791 |
| Title : ABHD11 maintains 2-oxoglutarate metabolism by preserving functional lipoylation of the 2-oxoglutarate dehydrogenase complex - Bailey_2020_Nat.Commun_11_4046 |
| Author(s) : Bailey PSJ , Ortmann BM , Martinelli AW , Houghton JW , Costa ASH , Burr SP , Antrobus R , Frezza C , Nathan JA |
| Ref : Nat Commun , 11 :4046 , 2020 |
| Abstract : |
| PubMedSearch : Bailey_2020_Nat.Commun_11_4046 |
| PubMedID: 32792488 |
| Gene_locus related to this paper: human-ABHD11 , mouse-Abhd11 |