| Title : Design and development of selective muscarinic agonists for the treatment of Alzheimer's disease: characterization of tetrahydropyrimidine derivatives and development of new approaches for improved affinity and selectivity for M1 receptors - Messer_2000_Pharm.Acta.Helv_74_135 |
| Author(s) : Messer WS, Jr. , Rajeswaran WG , Cao Y , Zhang HJ , el-Assadi AA , Dockery C , Liske J , O'Brien J , Williams FE , Huang XP , Wroblewski ME , Nagy PI , Peseckis SM |
| Ref : Pharm Acta Helv , 74 :135 , 2000 |
| Abstract : |
| PubMedSearch : Messer_2000_Pharm.Acta.Helv_74_135 |
| PubMedID: 10812950 |
| Title : Poster: Mutant M1 muscarinic receptors with enhanced agonist activity - |
| Author(s) : Huang XP , Williams FE , Peseckis SM , Messer WS, Jr. |
| Ref : Life Sciences , 64 :563 , 1999 |
| PubMedID: |
| Title : Roles of threonine 192 and asparagine 382 in agonist and antagonist interactions with M1 muscarinic receptors - Huang_1999_Br.J.Pharmacol_126_735 |
| Author(s) : Huang XP , Nagy PI , Williams FE , Peseckis SM , Messer WS, Jr. |
| Ref : British Journal of Pharmacology , 126 :735 , 1999 |
| Abstract : |
| PubMedSearch : Huang_1999_Br.J.Pharmacol_126_735 |
| PubMedID: 10188986 |
| Title : Poster: Mutant M1 muscarinic receptors with increased agonist affinity and G protein coupling - |
| Author(s) : Messer WS, Jr. , Huang XP , Nagy PI , Williams FE , Peseckis SM |
| Ref : Life Sciences , 64 :563 , 1999 |
| PubMedID: |
| Title : Differential modulation of agonist potency and receptor coupling by mutations of Ser388Tyr and Thr389Pro at the junction of transmembrane domain VI and the third extracellular loop of human M(1) muscarinic acetylcholine receptors - Huang_1999_Mol.Pharmacol_56_775 |
| Author(s) : Huang XP , Williams FE , Peseckis SM , Messer WS, Jr. |
| Ref : Molecular Pharmacology , 56 :775 , 1999 |
| Abstract : |
| PubMedSearch : Huang_1999_Mol.Pharmacol_56_775 |
| PubMedID: 10496961 |
| Title : First fatty acylated dipeptides to affect muscarinic receptor ligand binding - Krishnan_1999_Bioorg.Med.Chem.Lett_9_3363 |
| Author(s) : Krishnan V , Pham WN , Messer WS, Jr. , Peseckis SM |
| Ref : Bioorganic & Medicinal Chemistry Lett , 9 :3363 , 1999 |
| Abstract : |
| PubMedSearch : Krishnan_1999_Bioorg.Med.Chem.Lett_9_3363 |
| PubMedID: 10612600 |
| Title : Pharmacological characterization of human m1 muscarinic acetylcholine receptors with double mutations at the junction of TM VI and the third extracellular domain - Huang_1998_J.Pharmacol.Exp.Ther_286_1129 |
| Author(s) : Huang XP , Williams FE , Peseckis SM , Messer WS, Jr. |
| Ref : Journal of Pharmacology & Experimental Therapeutics , 286 :1129 , 1998 |
| Abstract : |
| PubMedSearch : Huang_1998_J.Pharmacol.Exp.Ther_286_1129 |
| PubMedID: 9732369 |
| Title : Poster: Molecular studies of agonist interactions with wild-type, T234A, and N507A m3 receptors - |
| Author(s) : Huang XP , Edgar MA , Freed J , Peseckis SM , Nagy PI , Ojo B , Zhang H , Messer WS, Jr. |
| Ref : Life Sciences , 60 :1178 , 1997 |
| PubMedID: |