Title : An esterase-responsive ibuprofen nano-micelle pre-modified embryo derived nucleus pulposus progenitor cells promote the regeneration of intervertebral disc degeneration - Xia_2023_Bioact.Mater_21_69 |
Author(s) : Xia KS , Li DD , Wang CG , Ying LW , Wang JK , Yang B , Shu JW , Huang XP , Zhang YA , Yu C , Zhou XP , Li FC , Slater NKH , Tang JB , Chen QX , Liang CZ |
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Abstract : |
PubMedSearch : Xia_2023_Bioact.Mater_21_69 |
PubMedID: 36017070 |
Title : NMDAR inhibition-independent antidepressant actions of ketamine metabolites - Zanos_2016_Nature_533_481 |
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Ref : Nature , 533 :481 , 2016 |
Abstract : |
PubMedSearch : Zanos_2016_Nature_533_481 |
PubMedID: 27144355 |
Title : Automated design of ligands to polypharmacological profiles - Besnard_2012_Nature_492_215 |
Author(s) : Besnard J , Ruda GF , Setola V , Abecassis K , Rodriguiz RM , Huang XP , Norval S , Sassano MF , Shin AI , Webster LA , Simeons FR , Stojanovski L , Prat A , Seidah NG , Constam DB , Bickerton GR , Read KD , Wetsel WC , Gilbert IH , Roth BL , Hopkins AL |
Ref : Nature , 492 :215 , 2012 |
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PubMedSearch : Besnard_2012_Nature_492_215 |
PubMedID: 23235874 |
Title : Heterotropic cooperativity within and between protomers of an oligomeric M(2) muscarinic receptor - Shivnaraine_2012_Biochemistry_51_4518 |
Author(s) : Shivnaraine RV , Huang XP , Seidenberg M , Ellis J , Wells JW |
Ref : Biochemistry , 51 :4518 , 2012 |
Abstract : |
PubMedSearch : Shivnaraine_2012_Biochemistry_51_4518 |
PubMedID: 22551249 |
Title : Poster: Synthesis and biological evaluation of bivalent xanomeline analogs as M1 muscarinic agonists - |
Author(s) : Messer WS, Jr. , Rajeswaran WG , Cao Y , Huang XP , Wroblewski ME , Nagy PI |
Ref : Life Sciences , 68 :2625 , 2001 |
PubMedID: |
Title : Design, synthesis, and biological characterization of bivalent 1-methyl-1,2,5,6-tetrahydropyridyl-1,2,5-thiadiazole derivatives as selective muscarinic agonists - Rajeswaran_2001_J.Med.Chem_44_4563 |
Author(s) : Rajeswaran WG , Cao Y , Huang XP , Wroblewski ME , Colclough T , Lee S , Liu F , Nagy PI , Ellis J , Levine BA , Nocka KH , Messer WS, Jr. |
Ref : Journal of Medicinal Chemistry , 44 :4563 , 2001 |
Abstract : |
PubMedSearch : Rajeswaran_2001_J.Med.Chem_44_4563 |
PubMedID: 11741475 |
Title : Design and development of selective muscarinic agonists for the treatment of Alzheimer's disease: characterization of tetrahydropyrimidine derivatives and development of new approaches for improved affinity and selectivity for M1 receptors - Messer_2000_Pharm.Acta.Helv_74_135 |
Author(s) : Messer WS, Jr. , Rajeswaran WG , Cao Y , Zhang HJ , el-Assadi AA , Dockery C , Liske J , O'Brien J , Williams FE , Huang XP , Wroblewski ME , Nagy PI , Peseckis SM |
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PubMedSearch : Messer_2000_Pharm.Acta.Helv_74_135 |
PubMedID: 10812950 |
Title : Roles of threonine 192 and asparagine 382 in agonist and antagonist interactions with M1 muscarinic receptors - Huang_1999_Br.J.Pharmacol_126_735 |
Author(s) : Huang XP , Nagy PI , Williams FE , Peseckis SM , Messer WS, Jr. |
Ref : British Journal of Pharmacology , 126 :735 , 1999 |
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PubMedSearch : Huang_1999_Br.J.Pharmacol_126_735 |
PubMedID: 10188986 |
Title : Poster: Mutant M1 muscarinic receptors with increased agonist affinity and G protein coupling - |
Author(s) : Messer WS, Jr. , Huang XP , Nagy PI , Williams FE , Peseckis SM |
Ref : Life Sciences , 64 :563 , 1999 |
PubMedID: |
Title : Differential modulation of agonist potency and receptor coupling by mutations of Ser388Tyr and Thr389Pro at the junction of transmembrane domain VI and the third extracellular loop of human M(1) muscarinic acetylcholine receptors - Huang_1999_Mol.Pharmacol_56_775 |
Author(s) : Huang XP , Williams FE , Peseckis SM , Messer WS, Jr. |
Ref : Molecular Pharmacology , 56 :775 , 1999 |
Abstract : |
PubMedSearch : Huang_1999_Mol.Pharmacol_56_775 |
PubMedID: 10496961 |
Title : Poster: Mutant M1 muscarinic receptors with enhanced agonist activity - |
Author(s) : Huang XP , Williams FE , Peseckis SM , Messer WS, Jr. |
Ref : Life Sciences , 64 :563 , 1999 |
PubMedID: |
Title : Poster: Activity of selective muscarinic agonists at human M1 receptors expressed at varying levels in A9 L cells - |
Author(s) : Cao Y , Wise DD , Zhang H , Huang XP , Messer WS, Jr. |
Ref : Life Sciences , 64 :571 , 1999 |
PubMedID: |
Title : Pharmacological characterization of human m1 muscarinic acetylcholine receptors with double mutations at the junction of TM VI and the third extracellular domain - Huang_1998_J.Pharmacol.Exp.Ther_286_1129 |
Author(s) : Huang XP , Williams FE , Peseckis SM , Messer WS, Jr. |
Ref : Journal of Pharmacology & Experimental Therapeutics , 286 :1129 , 1998 |
Abstract : |
PubMedSearch : Huang_1998_J.Pharmacol.Exp.Ther_286_1129 |
PubMedID: 9732369 |
Title : Poster: Development of 5-(3-alkenyl-1,2,4-oxadiazol-5-yl)-1,4,5,6-tetrahydropyrimidine derivatives as selective muscarinic agonists for the treatment of Alzheimer's disease - |
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Ref : Life Sciences , 60 :1163 , 1997 |
PubMedID: |
Title : Poster: Molecular studies of agonist interactions with wild-type, T234A, and N507A m3 receptors - |
Author(s) : Huang XP , Edgar MA , Freed J , Peseckis SM , Nagy PI , Ojo B , Zhang H , Messer WS, Jr. |
Ref : Life Sciences , 60 :1178 , 1997 |
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