| Title : Design and development of selective muscarinic agonists for the treatment of Alzheimer's disease: characterization of tetrahydropyrimidine derivatives and development of new approaches for improved affinity and selectivity for M1 receptors - Messer_2000_Pharm.Acta.Helv_74_135 |
| Author(s) : Messer WS, Jr. , Rajeswaran WG , Cao Y , Zhang HJ , el-Assadi AA , Dockery C , Liske J , O'Brien J , Williams FE , Huang XP , Wroblewski ME , Nagy PI , Peseckis SM |
| Ref : Pharm Acta Helv , 74 :135 , 2000 |
| Abstract : Messer_2000_Pharm.Acta.Helv_74_135 |
| ESTHER : Messer_2000_Pharm.Acta.Helv_74_135 |
| PubMedSearch : Messer_2000_Pharm.Acta.Helv_74_135 |
| PubMedID: 10812950 |
| Title : Poster: Development of 5-(3-alkenyl-1,2,4-oxadiazol-5-yl)-1,4,5,6-tetrahydropyrimidine derivatives as selective muscarinic agonists for the treatment of Alzheimer's disease - |
| Author(s) : Zhang H , Ojo B , Huang XP , Edgar MA , el-Assadi AA , Baril D , Lynch K , Wahidy S , Nagy PI , Messer WS, Jr. |
| Ref : Life Sciences , 60 :1163 , 1997 |
| PubMedID: |
| Title : Synthesis and biological characterization of 1,4,5,6-tetrahydropyrimidine and 2-amino-3,4,5,6-tetrahydropyridine derivatives as selective m1 agonists - Messer_1997_J.Med.Chem_40_1230 |
| Author(s) : Messer WS, Jr. , Abuh YF , Liu Y , Periyasamy S , Ngur DO , Edgar MA , el-Assadi AA , Sbeih S , Dunbar PG , Roknich S , Rho T , Fang Z , Ojo B , Zhang H , Huzl JJ, 3rd , Nagy PI |
| Ref : Journal of Medicinal Chemistry , 40 :1230 , 1997 |
| Abstract : Messer_1997_J.Med.Chem_40_1230 |
| ESTHER : Messer_1997_J.Med.Chem_40_1230 |
| PubMedSearch : Messer_1997_J.Med.Chem_40_1230 |
| PubMedID: 9111297 |
| Title : Synthesis and biochemical activity of novel amidine derivatives as m1 muscarinic receptor agonists - Ojo_1996_Bioorg.Med.Chem_4_1605 |
| Author(s) : Ojo B , Dunbar PG , Durant GJ , Nagy PI , Huzl JJ, 3rd , Periyasamy S , Ngur DO , el-Assadi AA , Hoss WP , Messer WS, Jr. |
| Ref : Bioorganic & Medicinal Chemistry , 4 :1605 , 1996 |
| Abstract : Ojo_1996_Bioorg.Med.Chem_4_1605 |
| ESTHER : Ojo_1996_Bioorg.Med.Chem_4_1605 |
| PubMedSearch : Ojo_1996_Bioorg.Med.Chem_4_1605 |
| PubMedID: 8931930 |
| Title : Poster: Neurochemical evaluation of the selective m1 muscarinic receptor agonist CDD-0097-A - |
| Author(s) : Messer WS, Jr. , Abuh YF , el-Assadi AA , Liu Y , Ojo B , Ryan K |
| Ref : Life Sciences , 56(11-12) :1005 , 1995 |
| PubMedID: |
| Title : Poster: Synthesis and structure-activity relationships of novel amidine derivatives as muscarinic receptor subtype-selective agonists - |
| Author(s) : Ojo B , Dunbar PG , Durant GJ , Huzl JJ, 3rd , el-Assadi AA , Periyasamy S , Ngur DO , Hoss WP , Messer WS, Jr. |
| Ref : Life Sciences , 56(11-12) :1005 , 1995 |
| PubMedID: |
| Title : Design, synthesis, and neurochemical evaluation of 5-(3-alkyl-1,2,4- oxadiazol-5-yl)-1,4,5,6-tetrahydropyrimidines as M1 muscarinic receptor agonists - Dunbar_1993_J.Med.Chem_36_842 |
| Author(s) : Dunbar PG , Durant GJ , Fang Z , Abuh YF , el-Assadi AA , Ngur DO , Periyasamy S , Hoss WP , Messer WS, Jr. |
| Ref : Journal of Medicinal Chemistry , 36 :842 , 1993 |
| Abstract : Dunbar_1993_J.Med.Chem_36_842 |
| ESTHER : Dunbar_1993_J.Med.Chem_36_842 |
| PubMedSearch : Dunbar_1993_J.Med.Chem_36_842 |
| PubMedID: 8464038 |