| Title : Discovery of the selective and nanomolar inhibitor of DPP-4 more potent than sitagliptin by structure-guided rational design - Mobeen_2024_Eur.J.Med.Chem_279_116834 |
| Author(s) : Mobeen B , Shah M , Rehman HM , Jan MS , Rashid U |
| Ref : Eur Journal of Medicinal Chemistry , 279 :116834 , 2024 |
| Abstract : |
| PubMedSearch : Mobeen_2024_Eur.J.Med.Chem_279_116834 |
| PubMedID: 39265251 |
| Title : Pregnenolone derivatives for the treatment of Alzheimer's disease: synthesis, and in vitro inhibition of amyloid beta(1-42) peptide aggregation, acetylcholinesterase and carbonic anhydrase-II - Tahir_2024_RSC.Adv_14_14742 |
| Author(s) : Tahir A , Mobeen B , Hussain F , Sadiq A , Rashid U |
| Ref : RSC Adv , 14 :14742 , 2024 |
| Abstract : |
| PubMedSearch : Tahir_2024_RSC.Adv_14_14742 |
| PubMedID: 38716099 |
| Title : SAR and lead optimization of (Z)-5-(4-hydroxy-3-methoxybenzylidene)-3-(2-morpholinoacetyl)thiazolidine-2,4-dione as a potential multi-target antidiabetic agent - Shah_2023_Eur.J.Med.Chem_258_115591 |
| Author(s) : Shah M , Jan MS , Sadiq A , Khan S , Rashid U |
| Ref : Eur Journal of Medicinal Chemistry , 258 :115591 , 2023 |
| Abstract : |
| PubMedSearch : Shah_2023_Eur.J.Med.Chem_258_115591 |
| PubMedID: 37393789 |
| Title : Evaluation of pyrimidine\/pyrrolidine-sertraline based hybrids as multitarget anti-Alzheimer agents: In-vitro, in-vivo, and computational studies - Javed_2023_Biomed.Pharmacother_159_114239 |
| Author(s) : Javed MA , Jan MS , Shbeer AM , Al-Ghorbani M , Rauf A , Wilairatana P , Mannan A , Sadiq A , Farooq U , Rashid U |
| Ref : Biomed Pharmacother , 159 :114239 , 2023 |
| Abstract : |
| PubMedSearch : Javed_2023_Biomed.Pharmacother_159_114239 |
| PubMedID: 36638595 |
| Title : Prospective Evaluation of an Amide-Based Zinc Scaffold as an Anti-Alzheimer Agent: In Vitro, In Vivo, and Computational Studies - Waseem_2022_ACS.Omega_7_26723 |
| Author(s) : Waseem W , Anwar F , Saleem U , Ahmad B , Zafar R , Anwar A , Saeed Jan M , Rashid U , Sadiq A , Ismail T |
| Ref : ACS Omega , 7 :26723 , 2022 |
| Abstract : |
| PubMedSearch : Waseem_2022_ACS.Omega_7_26723 |
| PubMedID: 35936440 |
| Title : In-Vitro, In-Vivo, Molecular Docking and ADMET Studies of 2-Substituted 3,7-Dihydroxy-4H-chromen-4-one for Oxidative Stress, Inflammation and Alzheimer's Disease - Mahnashi_2022_Metabolites_12_ |
| Author(s) : Mahnashi MH , Alshahrani MA , Nahari MH , Hassan SSU , Jan MS , Ayaz M , Ullah F , Alshehri OM , Alshehri MA , Rashid U , Sadiq A |
| Ref : Metabolites , 12 : , 2022 |
| Abstract : |
| PubMedSearch : Mahnashi_2022_Metabolites_12_ |
| PubMedID: 36355138 |
| Title : Diclofenac derivatives as concomitant inhibitors of cholinesterase, monoamine oxidase, cyclooxygenase-2 and 5-lipoxygenase for the treatment of Alzheimer's disease: synthesis, pharmacology, toxicity and docking studies - Javed_2022_RSC.Adv_12_22503 |
| Author(s) : Javed MA , Bibi S , Jan MS , Ikram M , Zaidi A , Farooq U , Sadiq A , Rashid U |
| Ref : RSC Adv , 12 :22503 , 2022 |
| Abstract : |
| PubMedSearch : Javed_2022_RSC.Adv_12_22503 |
| PubMedID: 36105972 |
| Title : Design, Synthesis, and Bioevaluation of Indole Core Containing 2-Arylidine Derivatives of Thiazolopyrimidine as Multitarget Inhibitors of Cholinesterases and Monoamine Oxidase A\/B for the Treatment of Alzheimer Disease - Shahid_2022_ACS.Omega_7_9369 |
| Author(s) : Shahid Nadeem M , Azam Khan J , Kazmi I , Rashid U |
| Ref : ACS Omega , 7 :9369 , 2022 |
| Abstract : |
| PubMedSearch : Shahid_2022_ACS.Omega_7_9369 |
| PubMedID: 35350344 |
| Title : Neuroprotective potentials of selected natural edible oils using enzyme inhibitory, kinetic and simulation approaches - Mahnashi_2021_BMC.Complement.Med.Ther_21_248 |
| Author(s) : Mahnashi MH , Alyami BA , Alqahtani YS , Alqarni AO , Jan MS , Ayaz M , Ullah F , Shahid M , Rashid U , Sadiq A |
| Ref : BMC Complement Med Ther , 21 :248 , 2021 |
| Abstract : |
| PubMedSearch : Mahnashi_2021_BMC.Complement.Med.Ther_21_248 |
| PubMedID: 34600509 |
| Title : Structural Modification, In Vitro, In Vivo, Ex Vivo, and In Silico Exploration of Pyrimidine and Pyrrolidine Cores for Targeting Enzymes Associated with Neuroinflammation and Cholinergic Deficit in Alzheimer's Disease - Javed_2021_ACS.Chem.Neurosci__ |
| Author(s) : Javed MA , Ashraf N , Saeed Jan M , Mahnashi MH , Alqahtani YS , Alyami BA , Alqarni AO , Asiri YI , Ikram M , Sadiq A , Rashid U |
| Ref : ACS Chem Neurosci , : , 2021 |
| Abstract : |
| PubMedSearch : Javed_2021_ACS.Chem.Neurosci__ |
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| Title : Fluoxetine and sertraline based multitarget inhibitors of cholinesterases and monoamine oxidase-A\/B for the treatment of Alzheimer's disease: Synthesis, pharmacology and molecular modeling studies - Nadeem_2021_Int.J.Biol.Macromol_193_19 |
| Author(s) : Nadeem MS , Khan JA , Rashid U |
| Ref : Int J Biol Macromol , 193 :19 , 2021 |
| Abstract : |
| PubMedSearch : Nadeem_2021_Int.J.Biol.Macromol_193_19 |
| PubMedID: 34687762 |
| Title : Comparative Cholinesterase, alpha-Glucosidase Inhibitory, Antioxidant, Molecular Docking, and Kinetic Studies on Potent Succinimide Derivatives - Ahmad_2020_Drug.Des.Devel.Ther_14_2165 |
| Author(s) : Ahmad A , Ullah F , Sadiq A , Ayaz M , Saeed Jan M , Shahid M , Wadood A , Mahmood F , Rashid U , Ullah R , Sahibzada MUK , Alqahtani AS , Mahmood HM |
| Ref : Drug Des Devel Ther , 14 :2165 , 2020 |
| Abstract : |
| PubMedSearch : Ahmad_2020_Drug.Des.Devel.Ther_14_2165 |
| PubMedID: 32606589 |
| Title : SAR based in-vitro anticholinesterase and molecular docking studies of nitrogenous progesterone derivatives - Amin_2020_Steroids__108599 |
| Author(s) : Amin MJ , Miana GA , Rashid U , Miraz Rahman K , Khan HU , Sadiq A |
| Ref : Steroids , :108599 , 2020 |
| Abstract : |
| PubMedSearch : Amin_2020_Steroids__108599 |
| PubMedID: 32126219 |
| Title : Evaluation of Cholinesterase Inhibitory Potential of Different Genotypes of Ziziphus nummularia, Their HPLC-UV, and Molecular Docking Analysis - Uddin_2020_Molecules_25_5011 |
| Author(s) : Uddin N , Ali N , Uddin Z , Nazir N , Zahoor M , Rashid U , Ullah R , Alqahtani AS , Alqahtani AM , Nasr FA , Liu M , Nisar M |
| Ref : Molecules , 25 :5011 , 2020 |
| Abstract : |
| PubMedSearch : Uddin_2020_Molecules_25_5011 |
| PubMedID: 33137939 |
| Title : Synthesis, in-vitro cholinesterase inhibition, in-vivo anticonvulsant activity and in-silico exploration of N-(4-methylpyridin-2-yl)thiophene-2-carboxamide analogs - Ahmad_2019_Bioorg.Chem_92_103216 |
| Author(s) : Ahmad G , Rasool N , Rizwan K , Imran I , Zahoor AF , Zubair M , Sadiq A , Rashid U |
| Ref : Bioorg Chem , 92 :103216 , 2019 |
| Abstract : |
| PubMedSearch : Ahmad_2019_Bioorg.Chem_92_103216 |
| PubMedID: 31491567 |
| Title : Pharmacological Evaluation of Aldehydic-Pyrrolidinedione Against HCT-116, MDA-MB231, NIH\/3T3, MCF-7 Cancer Cell Lines, Antioxidant and Enzyme Inhibition Studies - Ahmad_2019_Drug.Des.Devel.Ther_13_4185 |
| Author(s) : Ahmad A , Ullah F , Sadiq A , Ayaz M , Rahim H , Rashid U , Ahmad S , Jan MS , Ullah R , Shahat AA , Mahmood HM |
| Ref : Drug Des Devel Ther , 13 :4185 , 2019 |
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| PubMedSearch : Ahmad_2019_Drug.Des.Devel.Ther_13_4185 |
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| Title : Chemical Characterization, Analgesic, Antioxidant, and Anticholinesterase Potentials of Essential Oils From Isodon rugosus Wall. ex. Benth - Sadiq_2018_Front.Pharmacol_9_623 |
| Author(s) : Sadiq A , Zeb A , Ullah F , Ahmad S , Ayaz M , Rashid U , Muhammad N |
| Ref : Front Pharmacol , 9 :623 , 2018 |
| Abstract : |
| PubMedSearch : Sadiq_2018_Front.Pharmacol_9_623 |
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| Title : Conventional versus microwave assisted synthesis, molecular docking and enzyme inhibitory activities of new 3,4,5-trisubstituted-1,2,4-triazole analogues - Virk_2018_Pak.J.Pharm.Sci_31_1501 |
| Author(s) : Virk NA , Rehman A , Abbasi MA , Siddiqui SZ , Rashid U , Iqbal J , Saleem M , Ashraf M , Shahid W , Shah SAA |
| Ref : Pak J Pharm Sci , 31 :1501 , 2018 |
| Abstract : |
| PubMedSearch : Virk_2018_Pak.J.Pharm.Sci_31_1501 |
| PubMedID: 30058542 |
| Title : Design, synthesis and bioevaluation of tricyclic fused ring system as dual binding site acetylcholinesterase inhibitors - Tanoli_2018_Bioorg.Chem_83_336 |
| Author(s) : Tanoli ST , Ramzan M , Hassan A , Sadiq A , Jan MS , Khan FA , Ullah F , Ahmad H , Bibi M , Mahmood T , Rashid U |
| Ref : Bioorg Chem , 83 :336 , 2018 |
| Abstract : |
| PubMedSearch : Tanoli_2018_Bioorg.Chem_83_336 |
| PubMedID: 30399465 |
| Title : Synthesis, biological evaluation and docking studies of 2,3-dihydroquinazolin-4(1H)-one derivatives as inhibitors of cholinesterases - Sarfraz_2017_Bioorg.Chem_70_237 |
| Author(s) : Sarfraz M , Sultana N , Rashid U , Akram MS , Sadiq A , Tariq MI |
| Ref : Bioorg Chem , 70 :237 , 2017 |
| Abstract : |
| PubMedSearch : Sarfraz_2017_Bioorg.Chem_70_237 |
| PubMedID: 28126287 |
| Title : Neurologically Potent Molecules from Crataegus oxyacantha\; Isolation, Anticholinesterase Inhibition, and Molecular Docking - Ali_2017_Front.Pharmacol_8_327 |
| Author(s) : Ali M , Muhammad S , Shah MR , Khan A , Rashid U , Farooq U , Ullah F , Sadiq A , Ayaz M , Ahmad M , Latif A |
| Ref : Front Pharmacol , 8 :327 , 2017 |
| Abstract : |
| PubMedSearch : Ali_2017_Front.Pharmacol_8_327 |
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| Title : Synthesis, crystal structure determination, biological screening and docking studies of N1-substituted derivatives of 2,3-dihydroquinazolin-4(1H)-one as inhibitors of cholinesterases - Sultana_2017_Bioorg.Chem_72_256 |
| Author(s) : Sultana N , Sarfraz M , Tanoli ST , Akram MS , Sadiq A , Rashid U , Tariq MI |
| Ref : Bioorg Chem , 72 :256 , 2017 |
| Abstract : |
| PubMedSearch : Sultana_2017_Bioorg.Chem_72_256 |
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| Title : Solid-phase synthesis and biological evaluation of a parallel library of 2,3-dihydro-1,5-benzothiazepines - Ansari_2008_Bioorg.Med.Chem_16_7691 |
| Author(s) : Ansari FL , Iftikhar F , Ihsan Ul H , Mirza B , Baseer M , Rashid U |
| Ref : Bioorganic & Medicinal Chemistry , 16 :7691 , 2008 |
| Abstract : |
| PubMedSearch : Ansari_2008_Bioorg.Med.Chem_16_7691 |
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