Sadiq A

References (42)

Title : Pregnenolone derivatives for the treatment of Alzheimer's disease: synthesis, and in vitro inhibition of amyloid beta(1-42) peptide aggregation, acetylcholinesterase and carbonic anhydrase-II - Tahir_2024_RSC.Adv_14_14742
Author(s) : Tahir A , Mobeen B , Hussain F , Sadiq A , Rashid U
Ref : RSC Adv , 14 :14742 , 2024
Abstract :
PubMedSearch : Tahir_2024_RSC.Adv_14_14742
PubMedID: 38716099

Title : Exploring fluorine-substituted piperidines as potential therapeutics for diabetes mellitus and Alzheimer's diseases - Mughal_2024_Eur.J.Med.Chem_273_116523
Author(s) : Mughal EU , Hawsawi MB , Naeem N , Hassan A , Alluhaibi MS , Ali Shah SW , Nazir Y , Sadiq A , Alrafai HA , Ahmed SA
Ref : Eur Journal of Medicinal Chemistry , 273 :116523 , 2024
Abstract :
PubMedSearch : Mughal_2024_Eur.J.Med.Chem_273_116523
PubMedID: 38795518

Title : Evaluation of pyrimidine\/pyrrolidine-sertraline based hybrids as multitarget anti-Alzheimer agents: In-vitro, in-vivo, and computational studies - Javed_2023_Biomed.Pharmacother_159_114239
Author(s) : Javed MA , Jan MS , Shbeer AM , Al-Ghorbani M , Rauf A , Wilairatana P , Mannan A , Sadiq A , Farooq U , Rashid U
Ref : Biomed Pharmacother , 159 :114239 , 2023
Abstract :
PubMedSearch : Javed_2023_Biomed.Pharmacother_159_114239
PubMedID: 36638595

Title : Pharmacological evaluations of amide carboxylates as potential anti-Alzheimer agents: anti-radicals, enzyme inhibition, simulation and behavioral studies in animal models - Mahnashi_2023_J.Biomol.Struct.Dyn__1
Author(s) : Mahnashi MH , Ali S , O MA , Almazni IA , Asiri SA , Sadiq A , Zafar R , Jan MS
Ref : J Biomol Struct Dyn , :1 , 2023
Abstract :
PubMedSearch : Mahnashi_2023_J.Biomol.Struct.Dyn__1
PubMedID: 37642974

Title : Discovery of chalcone derivatives as potential a-glucosidase and cholinesterase inhibitors: Effect of hyperglycemia in paving a path to dementia - Al-ghulikah_2023_J.Mol.Struct_1276_134658
Author(s) : Al-ghulikah HA , Mughal EU , Elkaeed EB , Naeem N , Nazir Y , Alzahrani AYA , Sadiq A , Shah SWA
Ref : J Mol Struct , 1276 :134658 , 2023
Abstract :
PubMedSearch : Al-ghulikah_2023_J.Mol.Struct_1276_134658
PubMedID:

Title : Quantitative-HPLC-DAD polyphenols analysis, anxiolytic and cognition enhancing potentials of Sorbaria tomentosa Lindl. Rehder - Mahnashi_2023_J.Ethnopharmacol_317_116786
Author(s) : Mahnashi MH , Ayaz M , Alqahtani YS , Alyami BA , Shahid M , Alqahtani O , Kabrah SM , Zeb A , Ullah F , Sadiq A
Ref : J Ethnopharmacol , 317 :116786 , 2023
Abstract :
PubMedSearch : Mahnashi_2023_J.Ethnopharmacol_317_116786
PubMedID: 37328081

Title : Diclofenac derivatives as concomitant inhibitors of cholinesterase, monoamine oxidase, cyclooxygenase-2 and 5-lipoxygenase for the treatment of Alzheimer's disease: synthesis, pharmacology, toxicity and docking studies - Javed_2022_RSC.Adv_12_22503
Author(s) : Javed MA , Bibi S , Jan MS , Ikram M , Zaidi A , Farooq U , Sadiq A , Rashid U
Ref : RSC Adv , 12 :22503 , 2022
Abstract :
PubMedSearch : Javed_2022_RSC.Adv_12_22503
PubMedID: 36105972

Title : Inhibitory potential of nitrogen, oxygen and sulfur containing heterocyclic scaffolds against acetylcholinesterase and butyrylcholinesterase - Obaid_2022_RSC.Adv_12_19764
Author(s) : Obaid RJ , Naeem N , Mughal EU , Al-Rooqi MM , Sadiq A , Jassas RS , Moussa Z , Ahmed SA
Ref : RSC Adv , 12 :19764 , 2022
Abstract :
PubMedSearch : Obaid_2022_RSC.Adv_12_19764
PubMedID: 35919585

Title : Prospective Evaluation of an Amide-Based Zinc Scaffold as an Anti-Alzheimer Agent: In Vitro, In Vivo, and Computational Studies - Waseem_2022_ACS.Omega_7_26723
Author(s) : Waseem W , Anwar F , Saleem U , Ahmad B , Zafar R , Anwar A , Saeed Jan M , Rashid U , Sadiq A , Ismail T
Ref : ACS Omega , 7 :26723 , 2022
Abstract :
PubMedSearch : Waseem_2022_ACS.Omega_7_26723
PubMedID: 35936440

Title : In-Vitro, In-Vivo, Molecular Docking and ADMET Studies of 2-Substituted 3,7-Dihydroxy-4H-chromen-4-one for Oxidative Stress, Inflammation and Alzheimer's Disease - Mahnashi_2022_Metabolites_12_
Author(s) : Mahnashi MH , Alshahrani MA , Nahari MH , Hassan SSU , Jan MS , Ayaz M , Ullah F , Alshehri OM , Alshehri MA , Rashid U , Sadiq A
Ref : Metabolites , 12 : , 2022
Abstract :
PubMedSearch : Mahnashi_2022_Metabolites_12_
PubMedID: 36355138

Title : Succinimide Derivatives as Antioxidant Anticholinesterases, Anti-alpha-Amylase, and Anti-alpha-Glucosidase: In Vitro and In Silico Approaches - Alshehri_2022_Evid.Based.Complement.Alternat.Med_2022_6726438
Author(s) : Alshehri OM , Mahnashi MH , Sadiq A , Zafar R , Jan MS , Ullah F , Alshehri MA , Alshamrani S , Hassan EE
Ref : Evid Based Complement Alternat Med , 2022 :6726438 , 2022
Abstract :
PubMedSearch : Alshehri_2022_Evid.Based.Complement.Alternat.Med_2022_6726438
PubMedID: 35942378

Title : Neuroprotective potentials of selected natural edible oils using enzyme inhibitory, kinetic and simulation approaches - Mahnashi_2021_BMC.Complement.Med.Ther_21_248
Author(s) : Mahnashi MH , Alyami BA , Alqahtani YS , Alqarni AO , Jan MS , Ayaz M , Ullah F , Shahid M , Rashid U , Sadiq A
Ref : BMC Complement Med Ther , 21 :248 , 2021
Abstract :
PubMedSearch : Mahnashi_2021_BMC.Complement.Med.Ther_21_248
PubMedID: 34600509

Title : Prospective Application of Two New Pyridine-Based Zinc (II) Amide Carboxylate in Management of Alzheimer's Disease: Synthesis, Characterization, Computational and in vitro Approaches - Zafar_2021_Drug.Des.Devel.Ther_15_2679
Author(s) : Zafar R , Naureen H , Zubair M , Shahid K , Saeed Jan M , Akhtar S , Ahmad H , Waseem W , Haider A , Ali S , Tariq M , Sadiq A
Ref : Drug Des Devel Ther , 15 :2679 , 2021
Abstract :
PubMedSearch : Zafar_2021_Drug.Des.Devel.Ther_15_2679
PubMedID: 34188447

Title : Structural Modification, In Vitro, In Vivo, Ex Vivo, and In Silico Exploration of Pyrimidine and Pyrrolidine Cores for Targeting Enzymes Associated with Neuroinflammation and Cholinergic Deficit in Alzheimer's Disease - Javed_2021_ACS.Chem.Neurosci__
Author(s) : Javed MA , Ashraf N , Saeed Jan M , Mahnashi MH , Alqahtani YS , Alyami BA , Alqarni AO , Asiri YI , Ikram M , Sadiq A , Rashid U
Ref : ACS Chem Neurosci , : , 2021
Abstract :
PubMedSearch : Javed_2021_ACS.Chem.Neurosci__
PubMedID: 34643082

Title : Exploring 3-Benzyloxyflavones as new lead cholinesterase inhibitors: synthesis, structure-activity relationship and molecular modelling simulations - Mughal_2020_J.Biomol.Struct.Dyn__1
Author(s) : Mughal EU , Sadiq A , Ayub M , Naeem N , Javid A , Sumrra SH , Zafar MN , Khan BA , Malik FP , Ahmed I
Ref : J Biomol Struct Dyn , :1 , 2020
Abstract :
PubMedSearch : Mughal_2020_J.Biomol.Struct.Dyn__1
PubMedID: 32752941

Title : SAR based in-vitro anticholinesterase and molecular docking studies of nitrogenous progesterone derivatives - Amin_2020_Steroids__108599
Author(s) : Amin MJ , Miana GA , Rashid U , Miraz Rahman K , Khan HU , Sadiq A
Ref : Steroids , :108599 , 2020
Abstract :
PubMedSearch : Amin_2020_Steroids__108599
PubMedID: 32126219

Title : Zinc metal carboxylates as Potential anti-Alzheimer's candidate: In-vitro anticholinesterase, antioxidant and molecular docking studies - Zafar_2020_J.Biomol.Struct.Dyn__1
Author(s) : Zafar R , Zubair M , Ali S , Shahid K , Waseem W , Naureen H , Haider A , Saeed Jan M , Ullah F , Sirajuddin M , Sadiq A
Ref : J Biomol Struct Dyn , :1 , 2020
Abstract :
PubMedSearch : Zafar_2020_J.Biomol.Struct.Dyn__1
PubMedID: 32013770

Title : Comparative Cholinesterase, alpha-Glucosidase Inhibitory, Antioxidant, Molecular Docking, and Kinetic Studies on Potent Succinimide Derivatives - Ahmad_2020_Drug.Des.Devel.Ther_14_2165
Author(s) : Ahmad A , Ullah F , Sadiq A , Ayaz M , Saeed Jan M , Shahid M , Wadood A , Mahmood F , Rashid U , Ullah R , Sahibzada MUK , Alqahtani AS , Mahmood HM
Ref : Drug Des Devel Ther , 14 :2165 , 2020
Abstract :
PubMedSearch : Ahmad_2020_Drug.Des.Devel.Ther_14_2165
PubMedID: 32606589

Title : Neuroprotective Studies on Polygonum hydropiper L. Essential Oils Using Transgenic Animal Models - Tong_2020_Front.Pharmacol_11_580069
Author(s) : Tong X , Li X , Ayaz M , Ullah F , Sadiq A , Ovais M , Shahid M , Khayrullin M , Hazrat A
Ref : Front Pharmacol , 11 :580069 , 2020
Abstract :
PubMedSearch : Tong_2020_Front.Pharmacol_11_580069
PubMedID: 33584260

Title : Pharmacological Evaluation of Aldehydic-Pyrrolidinedione Against HCT-116, MDA-MB231, NIH\/3T3, MCF-7 Cancer Cell Lines, Antioxidant and Enzyme Inhibition Studies - Ahmad_2019_Drug.Des.Devel.Ther_13_4185
Author(s) : Ahmad A , Ullah F , Sadiq A , Ayaz M , Rahim H , Rashid U , Ahmad S , Jan MS , Ullah R , Shahat AA , Mahmood HM
Ref : Drug Des Devel Ther , 13 :4185 , 2019
Abstract :
PubMedSearch : Ahmad_2019_Drug.Des.Devel.Ther_13_4185
PubMedID: 31849450

Title : Flavonoids as Prospective Neuroprotectants and Their Therapeutic Propensity in Aging Associated Neurological Disorders - Ayaz_2019_Front.Aging.Neurosci_11_155
Author(s) : Ayaz M , Sadiq A , Junaid M , Ullah F , Ovais M , Ullah I , Ahmed J , Shahid M
Ref : Front Aging Neurosci , 11 :155 , 2019
Abstract :
PubMedSearch : Ayaz_2019_Front.Aging.Neurosci_11_155
PubMedID: 31293414

Title : Isolation of bioactive compounds from Bergenia ciliata (haw.) Sternb rhizome and their antioxidant and anticholinesterase activities - Zafar_2019_BMC.Complement.Altern.Med_19_296
Author(s) : Zafar R , Ullah H , Zahoor M , Sadiq A
Ref : BMC Complement Altern Med , 19 :296 , 2019
Abstract :
PubMedSearch : Zafar_2019_BMC.Complement.Altern.Med_19_296
PubMedID: 31694704

Title : Synthesis, in-vitro cholinesterase inhibition, in-vivo anticonvulsant activity and in-silico exploration of N-(4-methylpyridin-2-yl)thiophene-2-carboxamide analogs - Ahmad_2019_Bioorg.Chem_92_103216
Author(s) : Ahmad G , Rasool N , Rizwan K , Imran I , Zahoor AF , Zubair M , Sadiq A , Rashid U
Ref : Bioorg Chem , 92 :103216 , 2019
Abstract :
PubMedSearch : Ahmad_2019_Bioorg.Chem_92_103216
PubMedID: 31491567

Title : Flavonols and 4-thioflavonols as potential acetylcholinesterase and butyrylcholinesterase inhibitors: Synthesis, structure-activity relationship and molecular docking studies - Mughal_2019_Bioorg.Chem_91_103124
Author(s) : Mughal EU , Sadiq A , Ashraf J , Zafar MN , Sumrra SH , Tariq R , Mumtaz A , Javid A , Khan BA , Ali A , Javed CO
Ref : Bioorg Chem , 91 :103124 , 2019
Abstract :
PubMedSearch : Mughal_2019_Bioorg.Chem_91_103124
PubMedID: 31319297

Title : Synthesis, structure-activity relationship and molecular docking studies of 3-O-flavonol glycosides as cholinesterase inhibitors - Mughal_2018_Bioorg.Med.Chem_26_3696
Author(s) : Mughal EU , Javid A , Sadiq A , Murtaza S , Zafar MN , Khan BA , Sumrra SH , Tahir MN , Kanwal , Khan KM
Ref : Bioorganic & Medicinal Chemistry , 26 :3696 , 2018
Abstract :
PubMedSearch : Mughal_2018_Bioorg.Med.Chem_26_3696
PubMedID: 29886083

Title : Chemical Characterization, Analgesic, Antioxidant, and Anticholinesterase Potentials of Essential Oils From Isodon rugosus Wall. ex. Benth - Sadiq_2018_Front.Pharmacol_9_623
Author(s) : Sadiq A , Zeb A , Ullah F , Ahmad S , Ayaz M , Rashid U , Muhammad N
Ref : Front Pharmacol , 9 :623 , 2018
Abstract :
PubMedSearch : Sadiq_2018_Front.Pharmacol_9_623
PubMedID: 29950997

Title : Design, synthesis and bioevaluation of tricyclic fused ring system as dual binding site acetylcholinesterase inhibitors - Tanoli_2018_Bioorg.Chem_83_336
Author(s) : Tanoli ST , Ramzan M , Hassan A , Sadiq A , Jan MS , Khan FA , Ullah F , Ahmad H , Bibi M , Mahmood T , Rashid U
Ref : Bioorg Chem , 83 :336 , 2018
Abstract :
PubMedSearch : Tanoli_2018_Bioorg.Chem_83_336
PubMedID: 30399465

Title : Anticholinesterase and antioxidant potentials of Nonea micrantha Bioss. & Reut along with GC-MS analysis - Imran_2017_BMC.Complement.Altern.Med_17_499
Author(s) : Imran M , Ullah F , Ayaz M , Sadiq A , Shah MR , Jan MS
Ref : BMC Complement Altern Med , 17 :499 , 2017
Abstract :
PubMedSearch : Imran_2017_BMC.Complement.Altern.Med_17_499
PubMedID: 29169349

Title : Anti-Alzheimer's Studies on beta-Sitosterol Isolated from Polygonum hydropiper L - Ayaz_2017_Front.Pharmacol_8_697
Author(s) : Ayaz M , Junaid M , Ullah F , Subhan F , Sadiq A , Ali G , Ovais M , Shahid M , Ahmad A , Wadood A , El-Shazly M , Ahmad N , Ahmad S
Ref : Front Pharmacol , 8 :697 , 2017
Abstract :
PubMedSearch : Ayaz_2017_Front.Pharmacol_8_697
PubMedID: 29056913

Title : Synthesis, structure-activity relationship and molecular docking of 3-oxoaurones and 3-thioaurones as acetylcholinesterase and butyrylcholinesterase inhibitors - Mughal_2017_Bioorg.Med.Chem_25_100
Author(s) : Mughal EU , Sadiq A , Murtaza S , Rafique H , Zafar MN , Riaz T , Khan BA , Hameed A , Khan KM
Ref : Bioorganic & Medicinal Chemistry , 25 :100 , 2017
Abstract :
PubMedSearch : Mughal_2017_Bioorg.Med.Chem_25_100
PubMedID: 27780618

Title : Neuroprotective and Anti-Aging Potentials of Essential Oils from Aromatic and Medicinal Plants - Ayaz_2017_Front.Aging.Neurosci_9_168
Author(s) : Ayaz M , Sadiq A , Junaid M , Ullah F , Subhan F , Ahmed J
Ref : Front Aging Neurosci , 9 :168 , 2017
Abstract :
PubMedSearch : Ayaz_2017_Front.Aging.Neurosci_9_168
PubMedID: 28611658

Title : Neurologically Potent Molecules from Crataegus oxyacantha\; Isolation, Anticholinesterase Inhibition, and Molecular Docking - Ali_2017_Front.Pharmacol_8_327
Author(s) : Ali M , Muhammad S , Shah MR , Khan A , Rashid U , Farooq U , Ullah F , Sadiq A , Ayaz M , Ahmad M , Latif A
Ref : Front Pharmacol , 8 :327 , 2017
Abstract :
PubMedSearch : Ali_2017_Front.Pharmacol_8_327
PubMedID: 28638340

Title : Synthesis, crystal structure determination, biological screening and docking studies of N1-substituted derivatives of 2,3-dihydroquinazolin-4(1H)-one as inhibitors of cholinesterases - Sultana_2017_Bioorg.Chem_72_256
Author(s) : Sultana N , Sarfraz M , Tanoli ST , Akram MS , Sadiq A , Rashid U , Tariq MI
Ref : Bioorg Chem , 72 :256 , 2017
Abstract :
PubMedSearch : Sultana_2017_Bioorg.Chem_72_256
PubMedID: 28495556

Title : Synthesis, biological evaluation and docking studies of 2,3-dihydroquinazolin-4(1H)-one derivatives as inhibitors of cholinesterases - Sarfraz_2017_Bioorg.Chem_70_237
Author(s) : Sarfraz M , Sultana N , Rashid U , Akram MS , Sadiq A , Tariq MI
Ref : Bioorg Chem , 70 :237 , 2017
Abstract :
PubMedSearch : Sarfraz_2017_Bioorg.Chem_70_237
PubMedID: 28126287

Title : Chemical composition, antioxidant and anticholinesterase potentials of essential oil of Rumex hastatus D. Don collected from the North West of Pakistan - Ahmad_2016_BMC.Complement.Altern.Med_16_29
Author(s) : Ahmad S , Ullah F , Sadiq A , Ayaz M , Imran M , Ali I , Zeb A , Shah MR
Ref : BMC Complement Altern Med , 16 :29 , 2016
Abstract :
PubMedSearch : Ahmad_2016_BMC.Complement.Altern.Med_16_29
PubMedID: 26810212

Title : Antioxidant and anticholinesterase investigations of Rumex hastatus D. Don: potential effectiveness in oxidative stress and neurological disorders - Ahmad_2015_Biol.Res_48_20
Author(s) : Ahmad S , Ullah F , Ayaz M , Sadiq A , Imran M
Ref : Biol Res , 48 :20 , 2015
Abstract :
PubMedSearch : Ahmad_2015_Biol.Res_48_20
PubMedID: 25857346

Title : Anticholinesterse and antioxidant investigations of crude extracts, subsequent fractions, saponins and flavonoids of atriplex laciniata L.: potential effectiveness in Alzheimer's and other neurological disorders - Kamal_2015_Biol.Res_48_21
Author(s) : Kamal Z , Ullah F , Ayaz M , Sadiq A , Ahmad S , Zeb A , Hussain A , Imran M
Ref : Biol Res , 48 :21 , 2015
Abstract :
PubMedSearch : Kamal_2015_Biol.Res_48_21
PubMedID: 25889712

Title : Comparative chemical profiling, cholinesterase inhibitions and anti-radicals properties of essential oils from Polygonum hydropiper L: A Preliminary anti- Alzheimer's study - Ayaz_2015_Lipids.Health.Dis_14_141
Author(s) : Ayaz M , Junaid M , Ullah F , Sadiq A , Khan MA , Ahmad W , Shah MR , Imran M , Ahmad S
Ref : Lipids Health Dis , 14 :141 , 2015
Abstract :
PubMedSearch : Ayaz_2015_Lipids.Health.Dis_14_141
PubMedID: 26530857

Title : Synthesis, anticholinesterase and antioxidant potentials of ketoesters derivatives of succinimides: a possible role in the management of Alzheimer's - Sadiq_2015_Chem.Cent.J_9_31
Author(s) : Sadiq A , Mahmood F , Ullah F , Ayaz M , Ahmad S , Haq FU , Khan G , Jan MS
Ref : Chem Cent J , 9 :31 , 2015
Abstract :
PubMedSearch : Sadiq_2015_Chem.Cent.J_9_31
PubMedID: 26064188

Title : Phenolic, flavonoid contents, anticholinesterase and antioxidant evaluation of Iris germanica var\; florentina - Ullah_2015_Nat.Prod.Res__1
Author(s) : Ullah F , Ayaz M , Sadiq A , Hussain A , Ahmad S , Imran M , Zeb A
Ref : Nat Prod Res , :1 , 2015
Abstract :
PubMedSearch : Ullah_2015_Nat.Prod.Res__1
PubMedID: 26166432

Title : Phenolic contents, antioxidant and anticholinesterase potentials of crude extract, subsequent fractions and crude saponins from Polygonum hydropiper L - Ayaz_2014_BMC.Complement.Altern.Med_14_145
Author(s) : Ayaz M , Junaid M , Ahmed J , Ullah F , Sadiq A , Ahmad S , Imran M
Ref : BMC Complement Altern Med , 14 :145 , 2014
Abstract :
PubMedSearch : Ayaz_2014_BMC.Complement.Altern.Med_14_145
PubMedID: 24884823

Title : Investigations of anticholinestrase and antioxidant potentials of methanolic extract, subsequent fractions, crude saponins and flavonoids isolated from Isodon rugosus - Zeb_2014_Biol.Res_47_76
Author(s) : Zeb A , Sadiq A , Ullah F , Ahmad S , Ayaz M
Ref : Biol Res , 47 :76 , 2014
Abstract :
PubMedSearch : Zeb_2014_Biol.Res_47_76
PubMedID: 25723481