Schiavini P

Title : 3-Oxo-hexahydro-1H-isoindole-4-carboxylic Acid as a Drug Chiral Bicyclic Scaffold: Structure-Based Design and Preparation of Conformationally Constrained Covalent and Noncovalent Prolyl Oligopeptidase Inhibitors - Mariaule_2016_J.Med.Chem_59_4221

Author(s) : Mariaule G , De Cesco S , Airaghi F , Kurian J , Schiavini P , Rocheleau S , Huskic I , Auclair K , Mittermaier A , Moitessier N

Ref : Journal of Medicinal Chemistry , 59 :4221 , 2016

Abstract :

PubMedSearch : Mariaule_2016_J.Med.Chem_59_4221

PubMedID: 26619267

Gene_locus related to this paper: human-PREP

Title : Metabolic Instability of Cyanothiazolidine-Based Prolyl Oligopeptidase Inhibitors: a Structural Assignment Challenge and Potential Medicinal Chemistry Implications - Schiavini_2015_ChemMedChem_10_1174

Author(s) : Schiavini P , Pottel J , Moitessier N , Auclair K

Ref : ChemMedChem , 10 :1174 , 2015

Abstract :

PubMedSearch : Schiavini_2015_ChemMedChem_10_1174

PubMedID: 26018317

Schiavini P

References (2)

1. 3-Oxo-hexahydro-1H-isoindole-4-carboxylic Acid as a Drug Chiral Bicyclic Scaffold: Structure-Based Design and Preparation of Conformationally Constrained Covalent and Noncovalent Prolyl Oligopeptidase Inhibitors - Mariaule_2016_J.Med.Chem_59_4221

2. Metabolic Instability of Cyanothiazolidine-Based Prolyl Oligopeptidase Inhibitors: a Structural Assignment Challenge and Potential Medicinal Chemistry Implications - Schiavini_2015_ChemMedChem_10_1174