Title : Combined Ensemble Docking and Machine Learning in Identification of Therapeutic Agents with Potential Inhibitory Effect on Human CES1 - Briand_2019_Molecules_24_ |
Author(s) : Briand E , Thomsen R , Linnet K , Rasmussen HB , Brunak S , Taboureau O |
Ref : Molecules , 24 : , 2019 |
Abstract : |
PubMedSearch : Briand_2019_Molecules_24_ |
PubMedID: 31362390 |
Title : The impact of human CES1 genetic variation on enzyme activity assessed by ritalinic acid\/methylphenidate ratios - Stage_2019_Basic.Clin.Pharmacol.Toxicol_125_54 |
Author(s) : Stage C , Dalhoff K , Rasmussen HB , Schow Guski L , Thomsen R , Bjerre D , Ferrero-Miliani L , Busk Madsen M , Jurgens G |
Ref : Basic Clin Pharmacol Toxicol , 125 :54 , 2019 |
Abstract : |
PubMedSearch : Stage_2019_Basic.Clin.Pharmacol.Toxicol_125_54 |
PubMedID: 30801959 |
Gene_locus related to this paper: human-CES1 |
Title : Pharmacometabolomics Informs About Pharmacokinetic Profile of Methylphenidate - Kaddurah-Daouk_2018_CPT.Pharmacometrics.Syst.Pharmacol_7_525 |
Author(s) : Kaddurah-Daouk R , Hankemeier T , Scholl EH , Baillie R , Harms A , Stage C , Dalhoff KP , Jurgens G , Taboureau O , Nzabonimpa GS , Motsinger-Reif AA , Thomsen R , Linnet K , Rasmussen HB |
Ref : CPT Pharmacometrics Syst Pharmacol , 7 :525 , 2018 |
Abstract : |
PubMedSearch : Kaddurah-Daouk_2018_CPT.Pharmacometrics.Syst.Pharmacol_7_525 |
PubMedID: 30169917 |
Title : The impact of CES1 genotypes on the pharmacokinetics of methylphenidate in healthy Danish subjects - Stage_2017_Br.J.Clin.Pharmacol_83_1506 |
Author(s) : Stage C , Jurgens G , Guski LS , Thomsen R , Bjerre D , Ferrero-Miliani L , Lyauk YK , Rasmussen HB , Dalhoff K |
Ref : British Journal of Clinical Pharmacology , 83 :1506 , 2017 |
Abstract : |
PubMedSearch : Stage_2017_Br.J.Clin.Pharmacol_83_1506 |
PubMedID: 28087982 |
Gene_locus related to this paper: human-CES1 |
Title : The Pharmacokinetics of Enalapril in Relation to CES1 Genotype in Healthy Danish Volunteers - Stage_2017_Basic.Clin.Pharmacol.Toxicol_121_487 |
Author(s) : Stage C , Jurgens G , Guski LS , Thomsen R , Bjerre D , Ferrero-Miliani L , Lyauk YK , Rasmussen HB , Dalhoff K |
Ref : Basic Clin Pharmacol Toxicol , 121 :487 , 2017 |
Abstract : |
PubMedSearch : Stage_2017_Basic.Clin.Pharmacol.Toxicol_121_487 |
PubMedID: 28639420 |
Gene_locus related to this paper: human-CES1 |
Title : Population Pharmacokinetics of Methylphenidate in Healthy Adults Emphasizing Novel and Known Effects of Several Carboxylesterase 1 (CES1) Variants - Lyauk_2016_Clin.Transl.Sci_9_337 |
Author(s) : Lyauk YK , Stage C , Bergmann TK , Ferrero-Milliani L , Bjerre D , Thomsen R , Dalhoff KP , Rasmussen HB , Jurgens G |
Ref : Clin Transl Sci , 9 :337 , 2016 |
Abstract : |
PubMedSearch : Lyauk_2016_Clin.Transl.Sci_9_337 |
PubMedID: 27754602 |
Gene_locus related to this paper: human-CES1 |
Title : Synthetic cannabimimetic agents metabolized by carboxylesterases - Thomsen_2015_Drug.Test.Anal_7_565 |
Author(s) : Thomsen R , Nielsen LM , Holm NB , Rasmussen HB , Linnet K |
Ref : Drug Test Anal , 7 :565 , 2015 |
Abstract : |
PubMedSearch : Thomsen_2015_Drug.Test.Anal_7_565 |
PubMedID: 25346527 |
Title : In vitro drug metabolism by human carboxylesterase 1: focus on Angiotensin-converting enzyme inhibitors - Thomsen_2014_Drug.Metab.Dispos_42_126 |
Author(s) : Thomsen R , Rasmussen HB , Linnet K |
Ref : Drug Metabolism & Disposition: The Biological Fate of Chemicals , 42 :126 , 2014 |
Abstract : |
PubMedSearch : Thomsen_2014_Drug.Metab.Dispos_42_126 |
PubMedID: 24141856 |
Gene_locus related to this paper: human-CES1 |