| Title : Use of a probabilistic PBPK\/PD model to calculate Data Derived Extrapolation Factors for chlorpyrifos - Poet_2017_Regul.Toxicol.Pharmacol_86_59 |
| Author(s) : Poet TS , Timchalk C , Bartels MJ , Smith JN , McDougal R , Juberg DR , Price PS |
| Ref : Regul Toxicol Pharmacol , 86 :59 , 2017 |
| Abstract : |
| PubMedSearch : Poet_2017_Regul.Toxicol.Pharmacol_86_59 |
| PubMedID: 28238854 |
| Title : A human life-stage physiologically based pharmacokinetic and pharmacodynamic model for chlorpyrifos: Development and validation - Smith_2014_Regul.Toxicol.Pharmacol_69_580 |
| Author(s) : Smith JN , Hinderliter PM , Timchalk C , Bartels MJ , Poet TS |
| Ref : Regul Toxicol Pharmacol , 69 :580 , 2014 |
| Abstract : |
| PubMedSearch : Smith_2014_Regul.Toxicol.Pharmacol_69_580 |
| PubMedID: 24200834 |
| Title : Pharmacokinetics and Pharmacodynamics of Chlorpyrifos and 3,5,6-Trichloro-2-pyridinol in Rat Saliva After Chlorpyrifos Administration - Smith_2012_Toxicol.Sci_130_245 |
| Author(s) : Smith JN , Wang J , Lin Y , Klohe EM , Timchalk C |
| Ref : Toxicol Sci , 130 :245 , 2012 |
| Abstract : |
| PubMedSearch : Smith_2012_Toxicol.Sci_130_245 |
| PubMedID: 22874420 |
| Title : Development of a source-to-outcome model for dietary exposures to insecticide residues: an example using chlorpyrifos - Hinderliter_2011_Regul.Toxicol.Pharmacol_61_82 |
| Author(s) : Hinderliter PM , Price PS , Bartels MJ , Timchalk C , Poet TS |
| Ref : Regul Toxicol Pharmacol , 61 :82 , 2011 |
| Abstract : |
| PubMedSearch : Hinderliter_2011_Regul.Toxicol.Pharmacol_61_82 |
| PubMedID: 21722690 |
| Title : Enzyme-linked immunosorbent assay for detection of organophosphorylated butyrylcholinesterase: A biomarker of exposure to organophosphate agents - Wang_2011_Anal.Chim.Acta_693_1 |
| Author(s) : Wang L , Du D , Lu D , Lin CT , Smith JN , Timchalk C , Liu F , Wang J , Lin Y |
| Ref : Anal Chim Acta , 693 :1 , 2011 |
| Abstract : |
| PubMedSearch : Wang_2011_Anal.Chim.Acta_693_1 |
| PubMedID: 21504805 |
| Title : Impact of repeated nicotine and alcohol coexposure on in vitro and in vivo chlorpyrifos dosimetry and cholinesterase inhibition - Lee_2011_J.Toxicol.Environ.Health.A_74_1334 |
| Author(s) : Lee S , Poet TS , Smith JN , Hjerpe AL , Gunawan R , Timchalk C |
| Ref : J Toxicol Environ Health A , 74 :1334 , 2011 |
| Abstract : |
| PubMedSearch : Lee_2011_J.Toxicol.Environ.Health.A_74_1334 |
| PubMedID: 21899407 |
| Title : Magnetic electrochemical sensing platform for biomonitoring of exposure to organophosphorus pesticides and nerve agents based on simultaneous measurement of total enzyme amount and enzyme activity - Du_2011_Anal.Chem_83_3770 |
| Author(s) : Du D , Wang J , Wang L , Lu D , Smith JN , Timchalk C , Lin Y |
| Ref : Analytical Chemistry , 83 :3770 , 2011 |
| Abstract : |
| PubMedSearch : Du_2011_Anal.Chem_83_3770 |
| PubMedID: 21462919 |
| Title : Effect of in vivo nicotine exposure on chlorpyrifos pharmacokinetics and pharmacodynamics in rats - Lee_2010_Chem.Biol.Interact_184_449 |
| Author(s) : Lee S , Poet TS , Smith JN , Busby-Hjerpe AL , Timchalk C |
| Ref : Chemico-Biological Interactions , 184 :449 , 2010 |
| Abstract : |
| PubMedSearch : Lee_2010_Chem.Biol.Interact_184_449 |
| PubMedID: 20097188 |
| Title : Biomonitoring of organophosphorus agent exposure by reactivation of cholinesterase enzyme based on carbon nanotube-enhanced flow-injection amperometric detection - Du_2009_Anal.Chem_81_9314 |
| Author(s) : Du D , Wang J , Smith JN , Timchalk C , Lin Y |
| Ref : Analytical Chemistry , 81 :9314 , 2009 |
| Abstract : |
| PubMedSearch : Du_2009_Anal.Chem_81_9314 |
| PubMedID: 19839597 |
| Title : Cholinesterase inhibition in chlorpyrifos workers: Characterization of biomarkers of exposure and response in relation to urinary TCPy - Garabrant_2009_J.Expo.Sci.Environ.Epidemiol_19_634 |
| Author(s) : Garabrant DH , Aylward LL , Berent S , Chen Q , Timchalk C , Burns CJ , Hays SM , Albers JW |
| Ref : J Expo Sci Environ Epidemiol , 19 :634 , 2009 |
| Abstract : |
| PubMedSearch : Garabrant_2009_J.Expo.Sci.Environ.Epidemiol_19_634 |
| PubMedID: 18716607 |
| Title : Development of a physiologically based pharmacokinetic and pharmacodynamic model to determine dosimetry and cholinesterase inhibition for a binary mixture of chlorpyrifos and diazinon in the rat - Timchalk_2008_Neurotoxicol_29_428 |
| Author(s) : Timchalk C , Poet TS |
| Ref : Neurotoxicology , 29 :428 , 2008 |
| Abstract : |
| PubMedSearch : Timchalk_2008_Neurotoxicol_29_428 |
| PubMedID: 18394709 |
| Title : Nanoparticle-based electrochemical immunosensor for the detection of phosphorylated acetylcholinesterase: an exposure biomarker of organophosphate pesticides and nerve agents - Liu_2008_Chemistry_14_9951 |
| Author(s) : Liu G , Wang J , Barry R , Petersen C , Timchalk C , Gassman PL , Lin Y |
| Ref : Chemistry , 14 :9951 , 2008 |
| Abstract : |
| PubMedSearch : Liu_2008_Chemistry_14_9951 |
| PubMedID: 18942695 |
| Title : Magnetic electrochemical immunoassays with quantum dot labels for detection of phosphorylated acetylcholinesterase in plasma - Wang_2008_Anal.Chem_80_8477 |
| Author(s) : Wang H , Wang J , Timchalk C , Lin Y |
| Ref : Analytical Chemistry , 80 :8477 , 2008 |
| Abstract : |
| PubMedSearch : Wang_2008_Anal.Chem_80_8477 |
| PubMedID: 18855408 |
| Title : Carbon nanotube-based electrochemical sensor for assay of salivary cholinesterase enzyme activity: an exposure biomarker of organophosphate pesticides and nerve agents - Wang_2008_Environ.Sci.Technol_42_2688 |
| Author(s) : Wang J , Timchalk C , Lin Y |
| Ref : Environ Sci Technol , 42 :2688 , 2008 |
| Abstract : |
| PubMedSearch : Wang_2008_Environ.Sci.Technol_42_2688 |
| PubMedID: 18505017 |
| Title : Age-related brain cholinesterase inhibition kinetics following in vitro incubation with chlorpyrifos-oxon and diazinon-oxon - Kousba_2007_Toxicol.Sci_95_147 |
| Author(s) : Kousba AA , Poet TS , Timchalk C |
| Ref : Toxicol Sci , 95 :147 , 2007 |
| Abstract : |
| PubMedSearch : Kousba_2007_Toxicol.Sci_95_147 |
| PubMedID: 17018647 |
| Title : An age-dependent physiologically based pharmacokinetic\/pharmacodynamic model for the organophosphorus insecticide chlorpyrifos in the preweanling rat - Timchalk_2007_Toxicol.Sci_98_348 |
| Author(s) : Timchalk C , Kousba AA , Poet TS |
| Ref : Toxicol Sci , 98 :348 , 2007 |
| Abstract : |
| PubMedSearch : Timchalk_2007_Toxicol.Sci_98_348 |
| PubMedID: 17504771 |
| Title : Age-dependent pharmacokinetic and pharmacodynamic response in preweanling rats following oral exposure to the organophosphorus insecticide chlorpyrifos - Timchalk_2006_Toxicology_220_13 |
| Author(s) : Timchalk C , Poet TS , Kousba AA |
| Ref : Toxicology , 220 :13 , 2006 |
| Abstract : |
| PubMedSearch : Timchalk_2006_Toxicology_220_13 |
| PubMedID: 16343727 |
| Title : Toxicity of chlorpyrifos and chlorpyrifos oxon in a transgenic mouse model of the human paraoxonase (PON1) Q192R polymorphism - Cole_2005_Pharmacogenet.Genomics_15_589 |
| Author(s) : Cole TB , Walter BJ , Shih DM , Tward AD , Lusis AJ , Timchalk C , Richter RJ , Costa LG , Furlong CE |
| Ref : Pharmacogenet Genomics , 15 :589 , 2005 |
| Abstract : |
| PubMedSearch : Cole_2005_Pharmacogenet.Genomics_15_589 |
| PubMedID: 16007003 |
| Title : Paraoxonase 1 (PON1) status and risk of insecticide exposure - |
| Author(s) : Furlong CE , Cole TB , Walter BJ , Shih DM , Tward A , Lusis AJ , Timchalk C , Richter RJ , Costa LG |
| Ref : J Biochem Mol Toxicol , 19 :182 , 2005 |
| PubMedID: 15977192 |
| Title : Pharmacokinetic and pharmacodynamic interaction for a binary mixture of chlorpyrifos and diazinon in the rat - Timchalk_2005_Toxicol.Appl.Pharmacol_205_31 |
| Author(s) : Timchalk C , Poet TS , Hinman MN , Busby AL , Kousba AA |
| Ref : Toxicol Appl Pharmacol , 205 :31 , 2005 |
| Abstract : |
| PubMedSearch : Timchalk_2005_Toxicol.Appl.Pharmacol_205_31 |
| PubMedID: 15885262 |
| Title : Comparison of chlorpyrifos-oxon and paraoxon acetylcholinesterase inhibition dynamics: potential role of a peripheral binding site - Kousba_2004_Toxicol.Sci_80_239 |
| Author(s) : Kousba AA , Sultatos LG , Poet TS , Timchalk C |
| Ref : Toxicol Sci , 80 :239 , 2004 |
| Abstract : |
| PubMedSearch : Kousba_2004_Toxicol.Sci_80_239 |
| PubMedID: 15141101 |
| Title : Physiologically based pharmacokinetic\/pharmacodynamic model for the organophosphorus pesticide diazinon - Poet_2004_Neurotoxicol_25_1013 |
| Author(s) : Poet TS , Kousba AA , Dennison SL , Timchalk C |
| Ref : Neurotoxicology , 25 :1013 , 2004 |
| Abstract : |
| PubMedSearch : Poet_2004_Neurotoxicol_25_1013 |
| PubMedID: 15474619 |
| Title : Noninvasive biomonitoring approaches to determine dosimetry and risk following acute chemical exposure: analysis of lead or organophosphate insecticide in saliva - Timchalk_2004_J.Toxicol.Environ.Health.A_67_635 |
| Author(s) : Timchalk C , Poet TS , Kousba AA , Campbell JA , Lin Y |
| Ref : J Toxicol Environ Health A , 67 :635 , 2004 |
| Abstract : |
| PubMedSearch : Timchalk_2004_J.Toxicol.Environ.Health.A_67_635 |
| PubMedID: 15192859 |
| Title : Characterization of the in vitro kinetic interaction of chlorpyrifos-oxon with rat salivary cholinesterase: a potential biomonitoring matrix - Kousba_2003_Toxicology_188_219 |
| Author(s) : Kousba AA , Poet TS , Timchalk C |
| Ref : Toxicology , 188 :219 , 2003 |
| Abstract : |
| PubMedSearch : Kousba_2003_Toxicology_188_219 |
| PubMedID: 12767693 |
| Title : A Physiologically Based Pharmacokinetic and Pharmacodynamic (PBPK\/PD) Model for the Organophosphate Insecticide Chlorpyrifos in Rats and Humans - Timchalk_2002_Toxicol.Sci_66_34 |
| Author(s) : Timchalk C , Nolan RJ , Mendrala AL , Dittenber DA , Brzak KA , Mattsson JL |
| Ref : Toxicol Sci , 66 :34 , 2002 |
| Abstract : |
| PubMedSearch : Timchalk_2002_Toxicol.Sci_66_34 |
| PubMedID: 11861971 |