| Title : NOTUM promotes thermogenic capacity and protects against diet-induced obesity in male mice - Guo_2021_Sci.Rep_11_16409 |
| Author(s) : Guo F , Seldin M , Peterfy M , Charugundla S , Zhou Z , Lee SD , Mouton A , Rajbhandari P , Zhang W , Pellegrini M , Tontonoz P , Lusis AJ , Shih DM |
| Ref : Sci Rep , 11 :16409 , 2021 |
| Abstract : |
| PubMedSearch : Guo_2021_Sci.Rep_11_16409 |
| PubMedID: 34385484 |
| Title : Gene-by-Sex Interactions in Mitochondrial Functions and Cardio-Metabolic Traits - Norheim_2019_Cell.Metab_29_932 |
| Author(s) : Norheim F , Hasin-Brumshtein Y , Vergnes L , Chella Krishnan K , Pan C , Seldin MM , Hui ST , Mehrabian M , Zhou Z , Gupta S , Parks BW , Walch A , Reue K , Hofmann SM , Arnold AP , Lusis AJ |
| Ref : Cell Metab , 29 :932 , 2019 |
| Abstract : |
| PubMedSearch : Norheim_2019_Cell.Metab_29_932 |
| PubMedID: 30639359 |
| Gene_locus related to this paper: human-LYPLAL1 , mouse-lypl1 |
| Title : An integrative systems genetic analysis of mammalian lipid metabolism - Parker_2019_Nature_567_187 |
| Author(s) : Parker BL , Calkin AC , Seldin MM , Keating MF , Tarling EJ , Yang P , Moody SC , Liu Y , Zerenturk EJ , Needham EJ , Miller ML , Clifford BL , Morand P , Watt MJ , Meex RCR , Peng KY , Lee R , Jayawardana K , Pan C , Mellett NA , Weir JM , Lazarus R , Lusis AJ , Meikle PJ , James DE , de Aguiar Vallim TQ , Drew BG |
| Ref : Nature , 567 :187 , 2019 |
| Abstract : |
| PubMedSearch : Parker_2019_Nature_567_187 |
| PubMedID: 30814737 |
| Gene_locus related to this paper: human-ABHD1 , mouse-abhd1 |
| Title : Myeloperoxidase, paraoxonase-1, and HDL form a functional ternary complex - Huang_2013_J.Clin.Invest_123_3815 |
| Author(s) : Huang Y , Wu Z , Riwanto M , Gao S , Levison BS , Gu X , Fu X , Wagner MA , Besler C , Gerstenecker G , Zhang R , Li XM , Didonato AJ , Gogonea V , Tang WH , Smith JD , Plow EF , Fox PL , Shih DM , Lusis AJ , Fisher EA , Didonato JA , Landmesser U , Hazen SL |
| Ref : J Clinical Investigation , 123 :3815 , 2013 |
| Abstract : |
| PubMedSearch : Huang_2013_J.Clin.Invest_123_3815 |
| PubMedID: 23908111 |
| Title : Vasculitis, Atherosclerosis, and Altered HDL Composition in Heme-Oxygenase-1-Knockout Mice - Ishikawa_2012_Int.J.Hypertens_2012_948203 |
| Author(s) : Ishikawa K , Navab M , Lusis AJ |
| Ref : Int J Hypertens , 2012 :948203 , 2012 |
| Abstract : |
| PubMedSearch : Ishikawa_2012_Int.J.Hypertens_2012_948203 |
| PubMedID: 22518297 |
| Title : Paraoxonase-2 modulates stress response of endothelial cells to oxidized phospholipids and a bacterial quorum-sensing molecule - Kim_2011_Arterioscler.Thromb.Vasc.Biol_31_2624 |
| Author(s) : Kim JB , Xia YR , Romanoski CE , Lee S , Meng Y , Shi YS , Bourquard N , Gong KW , Port Z , Grijalva V , Reddy ST , Berliner JA , Lusis AJ , Shih DM |
| Ref : Arterioscler Thromb Vasc Biol , 31 :2624 , 2011 |
| Abstract : |
| PubMedSearch : Kim_2011_Arterioscler.Thromb.Vasc.Biol_31_2624 |
| PubMedID: 21836061 |
| Title : Temporal and tissue-specific patterns of Pon3 expression in mouse: in situ hybridization analysis - Shih_2010_Adv.Exp.Med.Biol_660_73 |
| Author(s) : Shih DM , Xia YR , Yu JM , Lusis AJ |
| Ref : Advances in Experimental Medicine & Biology , 660 :73 , 2010 |
| Abstract : |
| PubMedSearch : Shih_2010_Adv.Exp.Med.Biol_660_73 |
| PubMedID: 20221872 |
| Title : Chylomicronemia elicits atherosclerosis in mice--brief report - Weinstein_2010_Arterioscler.Thromb.Vasc.Biol_30_20 |
| Author(s) : Weinstein MM , Yin L , Tu Y , Wang X , Wu X , Castellani LW , Walzem RL , Lusis AJ , Fong LG , Beigneux AP , Young SG |
| Ref : Arterioscler Thromb Vasc Biol , 30 :20 , 2010 |
| Abstract : |
| PubMedSearch : Weinstein_2010_Arterioscler.Thromb.Vasc.Biol_30_20 |
| PubMedID: 19815815 |
| Title : The roles of PON1 and PON2 in cardiovascular disease and innate immunity - Shih_2009_Curr.Opin.Lipidol_20_288 |
| Author(s) : Shih DM , Lusis AJ |
| Ref : Curr Opin Lipidol , 20 :288 , 2009 |
| Abstract : |
| PubMedSearch : Shih_2009_Curr.Opin.Lipidol_20_288 |
| PubMedID: 19474728 |
| Title : A common mutation in paraoxonase-2 results in impaired lactonase activity - Stoltz_2009_J.Biol.Chem_284_35564 |
| Author(s) : Stoltz DA , Ozer EA , Recker TJ , Estin M , Yang X , Shih DM , Lusis AJ , Zabner J |
| Ref : Journal of Biological Chemistry , 284 :35564 , 2009 |
| Abstract : |
| PubMedSearch : Stoltz_2009_J.Biol.Chem_284_35564 |
| PubMedID: 19840942 |
| Title : Variations in DNA elucidate molecular networks that cause disease - Chen_2008_Nature_452_429 |
| Author(s) : Chen Y , Zhu J , Lum PY , Yang X , Pinto S , MacNeil DJ , Zhang C , Lamb J , Edwards S , Sieberts SK , Leonardson A , Castellini LW , Wang S , Champy MF , Zhang B , Emilsson V , Doss S , Ghazalpour A , Horvath S , Drake TA , Lusis AJ , Schadt EE |
| Ref : Nature , 452 :429 , 2008 |
| Abstract : |
| PubMedSearch : Chen_2008_Nature_452_429 |
| PubMedID: 18344982 |
| Title : Decreased obesity and atherosclerosis in human paraoxonase 3 transgenic mice - Shih_2007_Circ.Res_100_1200 |
| Author(s) : Shih DM , Xia YR , Wang XP , Wang SS , Bourquard N , Fogelman AM , Lusis AJ , Reddy ST |
| Ref : Circulation Research , 100 :1200 , 2007 |
| Abstract : |
| PubMedSearch : Shih_2007_Circ.Res_100_1200 |
| PubMedID: 17379834 |
| Title : Paraoxonase-2 deficiency enhances Pseudomonas aeruginosa quorum sensing in murine tracheal epithelia - Stoltz_2007_Am.J.Physiol.Lung.Cell.Mol.Physiol_292_L852 |
| Author(s) : Stoltz DA , Ozer EA , Ng CJ , Yu JM , Reddy ST , Lusis AJ , Bourquard N , Parsek MR , Zabner J , Shih DM |
| Ref : American Journal of Physiology Lung Cell Mol Physiol , 292 :L852 , 2007 |
| Abstract : |
| PubMedSearch : Stoltz_2007_Am.J.Physiol.Lung.Cell.Mol.Physiol_292_L852 |
| PubMedID: 17122353 |
| Title : Paraoxonase-2 deficiency aggravates atherosclerosis in mice despite lower apolipoprotein-B-containing lipoproteins: anti-atherogenic role for paraoxonase-2 - Ng_2006_J.Biol.Chem_281_29491 |
| Author(s) : Ng CJ , Bourquard N , Grijalva V , Hama S , Shih DM , Navab M , Fogelman AM , Lusis AJ , Young S , Reddy ST |
| Ref : Journal of Biological Chemistry , 281 :29491 , 2006 |
| Abstract : |
| PubMedSearch : Ng_2006_J.Biol.Chem_281_29491 |
| PubMedID: 16891303 |
| Title : Role of paraoxonase (PON1) status in pesticide sensitivity: genetic and temporal determinants - Furlong_2005_Neurotoxicol_26_651 |
| Author(s) : Furlong CE , Cole TB , Jarvik GP , Pettan-Brewer C , Geiss GK , Richter RJ , Shih DM , Tward AD , Lusis AJ , Costa LG |
| Ref : Neurotoxicology , 26 :651 , 2005 |
| Abstract : |
| PubMedSearch : Furlong_2005_Neurotoxicol_26_651 |
| PubMedID: 16112327 |
| Title : Paraoxonase 1 (PON1) status and risk of insecticide exposure - |
| Author(s) : Furlong CE , Cole TB , Walter BJ , Shih DM , Tward A , Lusis AJ , Timchalk C , Richter RJ , Costa LG |
| Ref : J Biochem Mol Toxicol , 19 :182 , 2005 |
| PubMedID: 15977192 |
| Title : Toxicity of chlorpyrifos and chlorpyrifos oxon in a transgenic mouse model of the human paraoxonase (PON1) Q192R polymorphism - Cole_2005_Pharmacogenet.Genomics_15_589 |
| Author(s) : Cole TB , Walter BJ , Shih DM , Tward AD , Lusis AJ , Timchalk C , Richter RJ , Costa LG , Furlong CE |
| Ref : Pharmacogenet Genomics , 15 :589 , 2005 |
| Abstract : |
| PubMedSearch : Cole_2005_Pharmacogenet.Genomics_15_589 |
| PubMedID: 16007003 |
| Title : Exon-intron organization and chromosomal localization of the mouse monoglyceride lipase gene - Karlsson_2001_Gene_272_11 |
| Author(s) : Karlsson M , Reue K , Xia YR , Lusis AJ , Langin D , Tornqvist H , Holm C |
| Ref : Gene , 272 :11 , 2001 |
| Abstract : |
| PubMedSearch : Karlsson_2001_Gene_272_11 |
| PubMedID: 11470505 |
| Gene_locus related to this paper: human-MGLL , mouse-MGLL |
| Title : Human paraoxonase-3 is an HDL-associated enzyme with biological activity similar to paraoxonase-1 protein but is not regulated by oxidized lipids - Reddy_2001_Arterioscler.Thromb.Vasc.Biol_21_542 |
| Author(s) : Reddy ST , Wadleigh DJ , Grijalva V , Ng C , Hama S , Gangopadhyay A , Shih DM , Lusis AJ , Navab M , Fogelman AM |
| Ref : Arterioscler Thromb Vasc Biol , 21 :542 , 2001 |
| Abstract : |
| PubMedSearch : Reddy_2001_Arterioscler.Thromb.Vasc.Biol_21_542 |
| PubMedID: 11304470 |
| Title : Genetic and temporal determinants of pesticide sensitivity: role of paraoxonase (PON1) - Furlong_2000_Neurotoxicol_21_91 |
| Author(s) : Furlong CE , Li WF , Richter RJ , Shih DM , Lusis AJ , Alleva E , Costa LG |
| Ref : Neurotoxicology , 21 :91 , 2000 |
| Abstract : |
| PubMedSearch : Furlong_2000_Neurotoxicol_21_91 |
| PubMedID: 10794389 |
| Title : Catalytic efficiency determines the in-vivo efficacy of PON1 for detoxifying organophosphorus compounds - Li_2000_Pharmacogenet_10_767 |
| Author(s) : Li WF , Costa LG , Richter RJ , Hagen T , Shih DM , Tward A , Lusis AJ , Furlong CE |
| Ref : Pharmacogenetics , 10 :767 , 2000 |
| Abstract : |
| PubMedSearch : Li_2000_Pharmacogenet_10_767 |
| PubMedID: 11191881 |
| Title : Paradoxical effect on atherosclerosis of hormone-sensitive lipase overexpression in macrophages - Escary_1999_J.Lipid.Res_40_397 |
| Author(s) : Escary JL , Choy HA , Reue K , Wang XP , Castellani LW , Glass CK , Lusis AJ , Schotz MC |
| Ref : J Lipid Res , 40 :397 , 1999 |
| Abstract : |
| PubMedSearch : Escary_1999_J.Lipid.Res_40_397 |
| PubMedID: 10064727 |
| Title : Paraoxonase and coronary heart disease - Mackness_1998_Curr.Opin.Lipidol_9_319 |
| Author(s) : Mackness MI , Mackness B , Durrington PN , Fogelman AM , Berliner J , Lusis AJ , Navab M , Shih DM , Fonarow GC |
| Ref : Curr Opin Lipidol , 9 :319 , 1998 |
| Abstract : |
| PubMedSearch : Mackness_1998_Curr.Opin.Lipidol_9_319 |
| PubMedID: 9739487 |
| Title : Mice lacking serum paraoxonase are susceptible to organophosphate toxicity and atherosclerosis - Shih_1998_Nature_394_284 |
| Author(s) : Shih DM , Gu L , Xia YR , Navab M , Li WF , Hama S , Castellani LW , Furlong CE , Costa LG , Fogelman AM , Lusis AJ |
| Ref : Nature , 394 :284 , 1998 |
| Abstract : |
| PubMedSearch : Shih_1998_Nature_394_284 |
| PubMedID: 9685159 |
| Title : Genetically determined susceptibility to organophosphorus insecticides and nerve agents: developing a mouse model for the human PON1 polymorphism - Furlong_1998_Neurotoxicol_19_645 |
| Author(s) : Furlong CE , Li WF , Costa LG , Richter RJ , Shih DM , Lusis AJ |
| Ref : Neurotoxicology , 19 :645 , 1998 |
| Abstract : |
| PubMedSearch : Furlong_1998_Neurotoxicol_19_645 |
| PubMedID: 9745924 |
| Title : Genetic contributions to quantitative lipoprotein traits associated with coronary artery disease: analysis of a large pedigree from the Bogalusa Heart Study - Heiba_1993_Am.J.Med.Genet_47_875 |
| Author(s) : Heiba IM , DeMeester CA , Xia YR , Diep A , George VT , Amos CI , Srinivasan SR , Berenson GS , Elston RC , Lusis AJ |
| Ref : American Journal of Medicine Genet , 47 :875 , 1993 |
| Abstract : |
| PubMedSearch : Heiba_1993_Am.J.Med.Genet_47_875 |
| PubMedID: 8279486 |
| Title : Chromosomal localization of lipolytic enzymes in the mouse: pancreatic lipase, colipase, hormone-sensitive lipase, hepatic lipase, and carboxyl ester lipase - Warden_1993_J.Lipid.Res_34_1451 |
| Author(s) : Warden CH , Davis RC , Yoon MY , Hui DY , Svenson K , Xia YR , Diep A , He KY , Lusis AJ |
| Ref : J Lipid Res , 34 :1451 , 1993 |
| Abstract : |
| PubMedSearch : Warden_1993_J.Lipid.Res_34_1451 |
| PubMedID: 8105016 |
| Title : Carboxyl ester lipase: a highly polymorphic locus on human chromosome 9qter - Taylor_1991_Genomics_10_425 |
| Author(s) : Taylor AK , Zambaux JL , Klisak I , Mohandas T , Sparkes RS , Schotz MC , Lusis AJ |
| Ref : Genomics , 10 :425 , 1991 |
| Abstract : |
| PubMedSearch : Taylor_1991_Genomics_10_425 |
| PubMedID: 1676983 |
| Gene_locus related to this paper: human-CEL |
| Title : DNA polymorphism haplotypes of the human lipoprotein lipase gene: possible association with high density lipoprotein levels - Heizmann_1991_Hum.Genet_86_578 |
| Author(s) : Heizmann C , Kirchgessner T , Kwiterovich PO , Ladias JA , Derby C , Antonarakis SE , Lusis AJ |
| Ref : Hum Genet , 86 :578 , 1991 |
| Abstract : |
| PubMedSearch : Heizmann_1991_Hum.Genet_86_578 |
| PubMedID: 1673959 |
| Title : Assignment of human pancreatic lipase gene (PNLIP) to chromosome 10q24-q26 - Davis_1991_Genomics_11_1164 |
| Author(s) : Davis RC , Diep A , Hunziker W , Klisak I , Mohandas T , Schotz MC , Sparkes RS , Lusis AJ |
| Ref : Genomics , 11 :1164 , 1991 |
| Abstract : |
| PubMedSearch : Davis_1991_Genomics_11_1164 |
| PubMedID: 1783385 |
| Gene_locus related to this paper: human-PNLIP |
| Title : Tissue-specific expression, developmental regulation, and chromosomal mapping of the lecithin: cholesterol acyltransferase gene. Evidence for expression in brain and testes as well as liver - Warden_1989_J.Biol.Chem_264_21573 |
| Author(s) : Warden CH , Langner CA , Gordon JI , Taylor BA , McLean JW , Lusis AJ |
| Ref : Journal of Biological Chemistry , 264 :21573 , 1989 |
| Abstract : |
| PubMedSearch : Warden_1989_J.Biol.Chem_264_21573 |
| PubMedID: 2600083 |
| Gene_locus related to this paper: mouse-lcat |
| Title : Genetic and developmental regulation of the lipoprotein lipase gene: loci both distal and proximal to the lipoprotein lipase structural gene control enzyme expression - Kirchgessner_1989_J.Biol.Chem_264_1473 |
| Author(s) : Kirchgessner TG , LeBoeuf RC , Langner CA , Zollman S , Chang CH , Taylor BA , Schotz MC , Gordon JI , Lusis AJ |
| Ref : Journal of Biological Chemistry , 264 :1473 , 1989 |
| Abstract : |
| PubMedSearch : Kirchgessner_1989_J.Biol.Chem_264_1473 |
| PubMedID: 2563260 |
| Gene_locus related to this paper: mouse-1hlip |
| Title : Two polymorphisms for the human hepatic lipase (HL) gene - |
| Author(s) : Heinzmann C , Ladias J , Antonarakis S , Diep A , Schotz M , Lusis AJ |
| Ref : Nucleic Acids Research , 16 :4739 , 1988 |
| PubMedID: 2454457 |
| Title : Nucleotide sequence of rat adipose hormone sensitive lipase cDNA - |
| Author(s) : Holm C , Kirchgessner TG , Svenson KL , Lusis AJ , Belfrage P , Schotz MC |
| Ref : Nucleic Acids Research , 16 :9879 , 1988 |
| PubMedID: 3186461 |
| Gene_locus related to this paper: ratno-hslip |
| Title : RFLP for the human lipoprotein lipase (LPL) gene: HindIII - |
| Author(s) : Heinzmann C , Ladias J , Antonarakis S , Kirchgessner T , Schotz M , Lusis AJ |
| Ref : Nucleic Acids Research , 15 :6763 , 1987 |
| PubMedID: 2888089 |
| Title : Human lipoprotein lipase complementary DNA sequence - Wion_1987_Science_235_1638 |
| Author(s) : Wion KL , Kirchgessner TG , Lusis AJ , Schotz MC , Lawn RM |
| Ref : Science , 235 :1638 , 1987 |
| Abstract : |
| PubMedSearch : Wion_1987_Science_235_1638 |
| PubMedID: 3823907 |
| Gene_locus related to this paper: human-LPL |
| Title : The sequence of cDNA encoding lipoprotein lipase. A member of a lipase gene family - Kirchgessner_1987_J.Biol.Chem_262_8463 |
| Author(s) : Kirchgessner TG , Svenson KL , Lusis AJ , Schotz MC |
| Ref : Journal of Biological Chemistry , 262 :8463 , 1987 |
| Abstract : |
| PubMedSearch : Kirchgessner_1987_J.Biol.Chem_262_8463 |
| PubMedID: 3597382 |
| Gene_locus related to this paper: mouse-lipli |
| Title : Human genes involved in lipolysis of plasma lipoproteins: mapping of loci for lipoprotein lipase to 8p22 and hepatic lipase to 15q21 - Sparkes_1987_Genomics_1_138 |
| Author(s) : Sparkes RS , Zollman S , Klisak I , Kirchgessner TG , Komaromy MC , Mohandas T , Schotz MC , Lusis AJ |
| Ref : Genomics , 1 :138 , 1987 |
| Abstract : |
| PubMedSearch : Sparkes_1987_Genomics_1_138 |
| PubMedID: 3692485 |
| Title : Preparation of microsomal beta-glucuronidase and its membrane anchor protein, egasyn - |
| Author(s) : Lusis AJ |
| Ref : Methods Enzymol , 96 :557 , 1983 |
| PubMedID: 6656645 |
| Gene_locus related to this paper: human-CES1 |
| Title : Relationships between levels of membrane-bound glucuronidase and the associated protein egasyn in mouse tissues - Lusis_1977_J.Cell.Biol_73_728 |
| Author(s) : Lusis AJ , Paigen K |
| Ref : Journal of Cell Biology , 73 :728 , 1977 |
| Abstract : |
| PubMedSearch : Lusis_1977_J.Cell.Biol_73_728 |
| PubMedID: 873997 |
| Gene_locus related to this paper: human-CES1 |
| Title : Inheritance in mice of the membrane anchor protein egasyn: the Eg locus determines egasyn levels - Lusis_1977_Biochem.Genet_15_115 |
| Author(s) : Lusis AJ , Tomino S , Paigen K |
| Ref : Biochemical Genetics , 15 :115 , 1977 |
| Abstract : |
| PubMedSearch : Lusis_1977_Biochem.Genet_15_115 |
| PubMedID: 849245 |
| Gene_locus related to this paper: human-CES1 |
| Title : Isolation, characterization, and radioimmunoassay of murine egasyn, a protein stabilizing glucuronidase membrane binding - Lusis_1976_J.Biol.Chem_251_7753 |
| Author(s) : Lusis AJ , Tomino S , Paigen K |
| Ref : Journal of Biological Chemistry , 251 :7753 , 1976 |
| Abstract : |
| PubMedSearch : Lusis_1976_J.Biol.Chem_251_7753 |
| PubMedID: 826534 |
| Gene_locus related to this paper: human-CES1 |