Title : Discovery of C-(1-aryl-cyclohexyl)-methylamines as selective, orally available inhibitors of dipeptidyl peptidase IV - Namoto_2014_Bioorg.Med.Chem.Lett_24_731 |
Author(s) : Namoto K , Sirockin F , Ostermann N , Gessier F , Flohr S , Sedrani R , Gerhartz B , Trappe J , Hassiepen U , Duttaroy A , Ferreira S , Sutton JM , Clark DE , Fenton G , Beswick M , Baeschlin DK |
Ref : Bioorganic & Medicinal Chemistry Lett , 24 :731 , 2014 |
Abstract : |
PubMedSearch : Namoto_2014_Bioorg.Med.Chem.Lett_24_731 |
PubMedID: 24439847 |
Gene_locus related to this paper: human-DPP4 |
Title : Novel heterocyclic DPP-4 inhibitors for the treatment of type 2 diabetes. - Sutton_2012_Bioorg.Med.Chem.Lett_22_1464 |
Author(s) : Sutton JM , Clark DE , Dunsdon SJ , Fenton G , Fillmore A , Harris NV , Higgs C , Hurley CA , Krintel SL , Mackenzie RE , Duttaroy A , Gangl E , Maniara W , Sedrani R , Namoto K , Ostermann N , Gerhartz B , Sirockin F , Trappe J , Hassiepen U , Baeschlin DK |
Ref : Bioorganic & Medicinal Chemistry Lett , 22 :1464 , 2012 |
Abstract : |
PubMedSearch : Sutton_2012_Bioorg.Med.Chem.Lett_22_1464 |
PubMedID: 22177783 |
Gene_locus related to this paper: human-DPP4 |
Title : Adverse effects of dipeptidyl peptidases 8 and 9 inhibition in rodents revisited - Burkey_2008_Diabetes.Obes.Metab_10_1057 |
Author(s) : Burkey BF , Hoffmann PK , Hassiepen U , Trappe J , Juedes M , Foley JE |
Ref : Diabetes Obes Metab , 10 :1057 , 2008 |
Abstract : |
PubMedSearch : Burkey_2008_Diabetes.Obes.Metab_10_1057 |
PubMedID: 18422675 |