Title : Discovery of C-(1-aryl-cyclohexyl)-methylamines as selective, orally available inhibitors of dipeptidyl peptidase IV - Namoto_2014_Bioorg.Med.Chem.Lett_24_731 |
Author(s) : Namoto K , Sirockin F , Ostermann N , Gessier F , Flohr S , Sedrani R , Gerhartz B , Trappe J , Hassiepen U , Duttaroy A , Ferreira S , Sutton JM , Clark DE , Fenton G , Beswick M , Baeschlin DK |
Ref : Bioorganic & Medicinal Chemistry Lett , 24 :731 , 2014 |
Abstract : |
PubMedSearch : Namoto_2014_Bioorg.Med.Chem.Lett_24_731 |
PubMedID: 24439847 |
Gene_locus related to this paper: human-DPP4 |
Title : Novel heterocyclic DPP-4 inhibitors for the treatment of type 2 diabetes. - Sutton_2012_Bioorg.Med.Chem.Lett_22_1464 |
Author(s) : Sutton JM , Clark DE , Dunsdon SJ , Fenton G , Fillmore A , Harris NV , Higgs C , Hurley CA , Krintel SL , Mackenzie RE , Duttaroy A , Gangl E , Maniara W , Sedrani R , Namoto K , Ostermann N , Gerhartz B , Sirockin F , Trappe J , Hassiepen U , Baeschlin DK |
Ref : Bioorganic & Medicinal Chemistry Lett , 22 :1464 , 2012 |
Abstract : |
PubMedSearch : Sutton_2012_Bioorg.Med.Chem.Lett_22_1464 |
PubMedID: 22177783 |
Gene_locus related to this paper: human-DPP4 |
Title : The DPP-4 inhibitor vildagliptin increases pancreatic beta cell mass in neonatal rats - Duttaroy_2011_Eur.J.Pharmacol_650_703 |
Author(s) : Duttaroy A , Voelker F , Merriam K , Zhang X , Ren X , Subramanian K , Hughes TE , Burkey BF |
Ref : European Journal of Pharmacology , 650 :703 , 2011 |
Abstract : |
PubMedSearch : Duttaroy_2011_Eur.J.Pharmacol_650_703 |
PubMedID: 21070766 |
Title : Inhibition of dipeptidyl peptidase-4 by vildagliptin during glucagon-like Peptide 1 infusion increases liver glucose uptake in the conscious dog - Edgerton_2009_Diabetes_58_243 |
Author(s) : Edgerton DS , Johnson KM , Neal DW , Scott M , Hobbs CH , Zhang X , Duttaroy A , Cherrington AD |
Ref : Diabetes , 58 :243 , 2009 |
Abstract : |
PubMedSearch : Edgerton_2009_Diabetes_58_243 |
PubMedID: 18840785 |
Title : M1-M3 muscarinic acetylcholine receptor-deficient mice: novel phenotypes - Gautam_2006_J.Mol.Neurosci_30_157 |
Author(s) : Gautam D , Duttaroy A , Cui Y , Han SJ , Deng C , Seeger T , Alzheimer C , Wess J |
Ref : Journal of Molecular Neuroscience , 30 :157 , 2006 |
Abstract : |
PubMedSearch : Gautam_2006_J.Mol.Neurosci_30_157 |
PubMedID: 17192665 |
Title : Generation and analysis of muscarinic acetylcholine receptor knockout mice. - |
Author(s) : Duttaroy A , Yamada M , Gomeza J , Zhang W , Miyakawa T , Makita R , Bymaster FP , Felder CC , Deng CX , Wess J |
Ref : Cholinergic Mechanisms, CRC Press :63 , 2004 |
PubMedID: |
Title : Muscarinic receptor subtypes mediating central and peripheral antinociception studied with muscarinic receptor knockout mice: a review - Wess_2003_Life.Sci_72_2047 |
Author(s) : Wess J , Duttaroy A , Gomeza J , Zhang W , Yamada M , Felder CC , Bernardini N , Reeh PW |
Ref : Life Sciences , 72 :2047 , 2003 |
Abstract : |
PubMedSearch : Wess_2003_Life.Sci_72_2047 |
PubMedID: 12628455 |
Title : Novel insights into M5 muscarinic acetylcholine receptor function by the use of gene targeting technology - Yamada_2003_Life.Sci_74_345 |
Author(s) : Yamada M , Basile AS , Fedorova I , Zhang W , Duttaroy A , Cui Y , Lamping KG , Faraci FM , Deng CX , Wess J |
Ref : Life Sciences , 74 :345 , 2003 |
Abstract : |
PubMedSearch : Yamada_2003_Life.Sci_74_345 |
PubMedID: 14607263 |
Title : Deletion of the M5 muscarinic acetylcholine receptor attenuates morphine reinforcement and withdrawal but not morphine analgesia - Basile_2002_Proc.Natl.Acad.Sci.U.S.A_99_11452 |
Author(s) : Basile AS , Fedorova I , Zapata A , Liu X , Shippenberg T , Duttaroy A , Yamada M , Wess J |
Ref : Proc Natl Acad Sci U S A , 99 :11452 , 2002 |
Abstract : |
PubMedSearch : Basile_2002_Proc.Natl.Acad.Sci.U.S.A_99_11452 |
PubMedID: 12154229 |
Title : Evaluation of muscarinic agonist-induced analgesia in muscarinic acetylcholine receptor knockout mice - Duttaroy_2002_Mol.Pharmacol_62_1084 |
Author(s) : Duttaroy A , Gomeza J , Gan JW , Siddiqui N , Basile AS , Harman WD , Smith PL , Felder CC , Levey AI , Wess J |
Ref : Molecular Pharmacology , 62 :1084 , 2002 |
Abstract : |
PubMedSearch : Duttaroy_2002_Mol.Pharmacol_62_1084 |
PubMedID: 12391271 |
Title : Generation and pharmacological analysis of M2 and M4 muscarinic receptor knockout mice - Gomeza_2001_Life.Sci_68(22-23)_2457 |
Author(s) : Gomeza J , Zhang L , Kostenis E , Felder CC , Bymaster FP , Brodkin J , Shannon HE , Xia B , Duttaroy A , Deng CX , Wess J |
Ref : Life Sciences , 68 :2457 , 2001 |
Abstract : |
PubMedSearch : Gomeza_2001_Life.Sci_68(22-23)_2457 |
PubMedID: 11392613 |