Full name : Wells James W
First name : James W
Mail : Department of Pharmaceutical Sciences, Leslie Dan Faculty of Pharmacy, University of Toronto , Toronto, Ontario
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Country : Canada
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Comment
| Title : Efficacy as an intrinsic property of the M(2) muscarinic receptor in its tetrameric state - Redka_2013_Biochemistry_52_7405 |
| Author(s) : Redka DS , Heerklotz H , Wells JW |
| Ref : Biochemistry , 52 :7405 , 2013 |
| Abstract : |
| PubMedSearch : Redka_2013_Biochemistry_52_7405 |
| PubMedID: 24047497 |
| Title : Heterotropic cooperativity within and between protomers of an oligomeric M(2) muscarinic receptor - Shivnaraine_2012_Biochemistry_51_4518 |
| Author(s) : Shivnaraine RV , Huang XP , Seidenberg M , Ellis J , Wells JW |
| Ref : Biochemistry , 51 :4518 , 2012 |
| Abstract : |
| PubMedSearch : Shivnaraine_2012_Biochemistry_51_4518 |
| PubMedID: 22551249 |
| Title : Cleavage-resistant fusion proteins of the M(2) muscarinic receptor and Galpha(i1). Homotropic and heterotropic effects in the binding of ligands - Ma_2011_Biochim.Biophys.Acta_1810_592 |
| Author(s) : Ma AW , Dong JY , Ma D , Wells JW |
| Ref : Biochimica & Biophysica Acta , 1810 :592 , 2011 |
| Abstract : |
| PubMedSearch : Ma_2011_Biochim.Biophys.Acta_1810_592 |
| PubMedID: 21397664 |
| Title : Oligomeric size of the m2 muscarinic receptor in live cells as determined by quantitative fluorescence resonance energy transfer - Pisterzi_2010_J.Biol.Chem_285_16723 |
| Author(s) : Pisterzi LF , Jansma DB , Georgiou J , Woodside MJ , Chou JT , Angers S , Raicu V , Wells JW |
| Ref : Journal of Biological Chemistry , 285 :16723 , 2010 |
| Abstract : |
| PubMedSearch : Pisterzi_2010_J.Biol.Chem_285_16723 |
| PubMedID: 20304928 |
| Title : Heterooligomers of the muscarinic receptor and G proteins purified from porcine atria - Ma_2008_Biochem.Biophys.Res.Commun_374_128 |
| Author(s) : Ma AW , Pawagi AB , Wells JW |
| Ref : Biochemical & Biophysical Research Communications , 374 :128 , 2008 |
| Abstract : |
| PubMedSearch : Ma_2008_Biochem.Biophys.Res.Commun_374_128 |
| PubMedID: 18601900 |
| Title : Binding of orthosteric ligands to the allosteric site of the M(2) muscarinic cholinergic receptor - Redka_2008_Mol.Pharmacol_74_834 |
| Author(s) : Redka DS , Pisterzi LF , Wells JW |
| Ref : Molecular Pharmacology , 74 :834 , 2008 |
| Abstract : |
| PubMedSearch : Redka_2008_Mol.Pharmacol_74_834 |
| PubMedID: 18552124 |
| Title : Recovery of oligomers and cooperativity when monomers of the M2 muscarinic cholinergic receptor are reconstituted into phospholipid vesicles - Ma_2007_Biochemistry_46_7907 |
| Author(s) : Ma AW , Redka DS , Pisterzi LF , Angers S , Wells JW |
| Ref : Biochemistry , 46 :7907 , 2007 |
| Abstract : |
| PubMedSearch : Ma_2007_Biochemistry_46_7907 |
| PubMedID: 17552496 |
| Title : Cholesterol as a determinant of cooperativity in the M2 muscarinic cholinergic receptor - Colozo_2007_Biochem.Pharmacol_74_236 |
| Author(s) : Colozo AT , Park PS , Sum CS , Pisterzi LF , Wells JW |
| Ref : Biochemical Pharmacology , 74 :236 , 2007 |
| Abstract : |
| PubMedSearch : Colozo_2007_Biochem.Pharmacol_74_236 |
| PubMedID: 17521619 |
| Title : Characterization of radioligand binding to a transmembrane receptor reconstituted into Lipobeads - Park_2004_FEBS.Lett_567_344 |
| Author(s) : Park PS , Ng CC , Buck S , Wells JW , Cheng YL , Pennefather PS |
| Ref : FEBS Letters , 567 :344 , 2004 |
| Abstract : |
| PubMedSearch : Park_2004_FEBS.Lett_567_344 |
| PubMedID: 15178349 |
| Title : Oligomeric potential of the M2 muscarinic cholinergic receptor - Park_2004_J.Neurochem_90_537 |
| Author(s) : Park PS , Wells JW |
| Ref : Journal of Neurochemistry , 90 :537 , 2004 |
| Abstract : |
| PubMedSearch : Park_2004_J.Neurochem_90_537 |
| PubMedID: 15255931 |
| Title : Mathematical basis for the optimization of single cell-line screening on multi-well plates - Ma_2004_Biotechnol.Lett_26_1441 |
| Author(s) : Ma D , Wells JW |
| Ref : Biotechnol Lett , 26 :1441 , 2004 |
| Abstract : |
| PubMedSearch : Ma_2004_Biotechnol.Lett_26_1441 |
| PubMedID: 15604778 |
| Title : Monomers and oligomers of the M2 muscarinic cholinergic receptor purified from Sf9 cells - Park_2003_Biochemistry_42_12960 |
| Author(s) : Park PS , Wells JW |
| Ref : Biochemistry , 42 :12960 , 2003 |
| Abstract : |
| PubMedSearch : Park_2003_Biochemistry_42_12960 |
| PubMedID: 14596611 |
| Title : Cooperativity and oligomeric status of cardiac muscarinic cholinergic receptors - Park_2002_Biochemistry_41_5588 |
| Author(s) : Park PS , Sum CS , Pawagi AB , Wells JW |
| Ref : Biochemistry , 41 :5588 , 2002 |
| Abstract : |
| PubMedSearch : Park_2002_Biochemistry_41_5588 |
| PubMedID: 11969420 |
| Title : Effects of N-ethylmaleimide on conformational equilibria in purified cardiac muscarinic receptors - Sum_2002_J.Biol.Chem_277_36188 |
| Author(s) : Sum CS , Park PS , Wells JW |
| Ref : Journal of Biological Chemistry , 277 :36188 , 2002 |
| Abstract : |
| PubMedSearch : Sum_2002_J.Biol.Chem_277_36188 |
| PubMedID: 12119286 |
| Title : Nature of the oligomers formed by muscarinic m2 acetylcholine receptors in Sf9 cells - Park_2001_Eur.J.Pharmacol_421_11 |
| Author(s) : Park P , Sum CS , Hampson DR , Van Tol HH , Wells JW |
| Ref : European Journal of Pharmacology , 421 :11 , 2001 |
| Abstract : |
| PubMedSearch : Park_2001_Eur.J.Pharmacol_421_11 |
| PubMedID: 11408044 |
| Title : Apparent capacity of cardiac muscarinic receptors for different radiolabeled antagonists - Sum_2001_Biochem.Pharmacol_62_829 |
| Author(s) : Sum CS , Pyo N , Wells JW |
| Ref : Biochemical Pharmacology , 62 :829 , 2001 |
| Abstract : |
| PubMedSearch : Sum_2001_Biochem.Pharmacol_62_829 |
| PubMedID: 11543719 |
| Title : Poster: Oligomeric stability of the M2 muscarinic receptor - |
| Author(s) : Park P , Van Tol HH , Wells JW |
| Ref : Life Sciences , 68 :2622 , 2001 |
| PubMedID: |
| Title : Cardiac muscarinic receptors. Relationship between the G protein and multiple states of affinity - Green_1997_Biochemistry_36_7380 |
| Author(s) : Green MA , Chidiac P , Wells JW |
| Ref : Biochemistry , 36 :7380 , 1997 |
| Abstract : |
| PubMedSearch : Green_1997_Biochemistry_36_7380 |
| PubMedID: 9200685 |
| Title : Cardiac muscarinic receptors. Cooperativity as the basis for multiple states of affinity - Chidiac_1997_Biochemistry_36_7361 |
| Author(s) : Chidiac P , Green MA , Pawagi AB , Wells JW |
| Ref : Biochemistry , 36 :7361 , 1997 |
| Abstract : |
| PubMedSearch : Chidiac_1997_Biochemistry_36_7361 |
| PubMedID: 9200684 |
| Title : Constitutive activation of the m5 muscarinic receptor by a series of mutations at the extracellular end of transmembrane 6 - Spalding_1997_Biochemistry_36_10109 |
| Author(s) : Spalding TA , Burstein ES , Wells JW , Brann MR |
| Ref : Biochemistry , 36 :10109 , 1997 |
| Abstract : |
| PubMedSearch : Spalding_1997_Biochemistry_36_10109 |
| PubMedID: 9254607 |
| Title : Cooperativity manifest in the binding properties of purified cardiac muscarinic receptors - Wreggett_1995_J.Biol.Chem_270_22488 |
| Author(s) : Wreggett KA , Wells JW |
| Ref : Journal of Biological Chemistry , 270 :22488 , 1995 |
| Abstract : |
| PubMedSearch : Wreggett_1995_J.Biol.Chem_270_22488 |
| PubMedID: 7673239 |
| Title : Effects of adenyl nucleotides and carbachol on cooperative interactions among G proteins - Chidiac_1992_Biochemistry_31_10908 |
| Author(s) : Chidiac P , Wells JW |
| Ref : Biochemistry , 31 :10908 , 1992 |
| Abstract : |
| PubMedSearch : Chidiac_1992_Biochemistry_31_10908 |
| PubMedID: 1420202 |
| Title : Inefficient muscarinic transduction in cardiomyopathic Syrian hamsters - Chidiac_1991_J.Mol.Cell.Cardiol_23_1255 |
| Author(s) : Chidiac P , Nagy A , Sole MJ , Wells JW |
| Ref : Journal of Molecular & Cellular Cardiology , 23 :1255 , 1991 |
| Abstract : |
| PubMedSearch : Chidiac_1991_J.Mol.Cell.Cardiol_23_1255 |
| PubMedID: 1666414 |
| Title : Assessment of mechanistic proposals for the binding of agonists to cardiac muscarinic receptors - Wong_1986_Biochemistry_25_6995 |
| Author(s) : Wong HM , Sole MJ , Wells JW |
| Ref : Biochemistry , 25 :6995 , 1986 |
| Abstract : |
| PubMedSearch : Wong_1986_Biochemistry_25_6995 |
| PubMedID: 3801407 |
| Title : Assessment of a ternary model for the binding of agonists to neurohumoral receptors - Lee_1986_Biochemistry_25_7009 |
| Author(s) : Lee TW , Sole MJ , Wells JW |
| Ref : Biochemistry , 25 :7009 , 1986 |
| Abstract : |
| PubMedSearch : Lee_1986_Biochemistry_25_7009 |
| PubMedID: 2879554 |
| Title : Competitive binding studies with multiple sites. Effects arising from depletion of the free radioligand - Wells_1980_Biochim.Biophys.Acta_632_464 |
| Author(s) : Wells JW , Birdsall NJ , Burgen AS , Hulme EC |
| Ref : Biochimica & Biophysica Acta , 632 :464 , 1980 |
| Abstract : |
| PubMedSearch : Wells_1980_Biochim.Biophys.Acta_632_464 |
| PubMedID: 7417533 |
| Title : The effects of ions on the binding of agonists and antagonists to muscarinic receptors - Birdsall_1979_Br.J.Pharmacol_67_371 |
| Author(s) : Birdsall NJ , Burgen AS , Hulme EC , Wells JW |
| Ref : British Journal of Pharmacology , 67 :371 , 1979 |
| Abstract : |
| PubMedSearch : Birdsall_1979_Br.J.Pharmacol_67_371 |
| PubMedID: 497538 |
| Title : Muscarinic receptors: ionic perturbation of the binding properties [proceedings] - |
| Author(s) : Birdsall NJ , Burgen AS , Hulme EC , Wells JW |
| Ref : British Journal of Pharmacology , 59 :503P , 1977 |
| PubMedID: 843741 |