Taylor P

General

Full name : Taylor Palmer

First name : Palmer

Mail : Skaggs School of Pharmacy and Pharmaceutical Sciences\; University of California\; San Diego\; 9500 Gilman Drive\; La Jolla\; CA 92093

Zip Code :

City : San Diego

Country : USA

Email : pwtaylor@health.ucsd.edu

Phone : +18585344028

Fax :

Website : \/\/pharmacy.ucsd.edu\/faculty\/bios\/taylor.shtml

Directory :

References (324)

Title : A single post-exposure oxime RS194B treatment rapidly reactivates acetylcholinesterase and reverses acute symptoms in macaques exposed to diethylphosphorothioate parathion and chlorpyrifos insecticides - Rosenberg_2023_J.Neurochem_17thISCM_
Author(s) : Rosenberg YJ , Garcia K , Diener J , Sullivan D , Donahue S , Mao L , Lees J , Jiang X , Urban LA , Momper JD , Ho KY , Taylor P
Ref : Journal of Neurochemistry , : , 2023
PubMedID: 36786545

Title : Ligand design for human acetylcholinesterase and nicotinic acetylcholine receptors, extending beyond the conventional and canonical - Taylor_2021_J.Neurochem__
Author(s) : Taylor P , Shong YJ , Samskey N , Ho KY , Radic Z , Fenical W , Sharpless KB , Kovarik Z , Andrea Camacho-Hernandez G
Ref : Journal of Neurochemistry , : , 2021
PubMedID: 33638151

Title : Cholinergic Capsules and Academic Admonitions - Taylor_2021_Annu.Rev.Pharmacol.Toxicol_61_25
Author(s) : Taylor P
Ref : Annual Review of Pharmacology & Toxicology , 61 :25 , 2021
PubMedID: 33411578

Title : Covalent inhibition of hAChE by organophosphates causes homodimer dissociation through long-range allosteric effects - Blumenthal_2021_J.Biol.Chem__
Author(s) : Blumenthal DK , Cheng X , Fajer M , Ho KY , Rohrer J , Gerlits O , Taylor P , Juneja P , Kovalevsky A , Radic Z
Ref : Journal of Biological Chemistry , :101007 , 2021
PubMedID: 34324828
Gene_locus related to this paper: human-ACHE

Title : Enhancing target tissue levels and diminishing plasma clearance of ionizing zwitterionic antidotes in organophosphate exposures - Shyong_2021_J.Pharmacol.Exp.Ther__
Author(s) : Shyong YJ , Sepulveda Y , Garcia A , Samskey NM , Radic Z , Sit R , Sharpless KB , Momper JD , Taylor P
Ref : Journal of Pharmacology & Experimental Therapeutics , : , 2021
PubMedID: 34145064

Title : Positron emission tomography evaluation of oxime countermeasures in live rats using the tracer O-(2-[(18) F]fluoroethyl)-O-(p-nitrophenyl)methylphosphonate [(18) F]-VXS - Hayes_2020_Ann.N.Y.Acad.Sci__
Author(s) : Hayes TR , Blecha JE , Chao CK , Huynh TL , VanBrocklin HD , Zinn KR , Taylor P , Gerdes JM , Thompson CM
Ref : Annals of the New York Academy of Sciences , : , 2020
PubMedID: 32436233

Title : Rational design, synthesis and evaluation of uncharged, smart bis-oxime antidotes of organophosphate-inhibited human acetylcholinesterase - Gorecki_2020_J.Biol.Chem_295_4079
Author(s) : Gorecki L , Gerlits O , Kong X , Cheng X , Blumenthal DK , Taylor P , Ballatore C , Kovalevsky A , Radic Z
Ref : Journal of Biological Chemistry , 295 :4079 , 2020
PubMedID: 32019865
Gene_locus related to this paper: human-ACHE

Title : Evaluation of high-affinity phenyltetrahydroisoquinoline aldoximes, linked through anti-triazoles, as reactivators of phosphylated cholinesterases - Macek Hrvat_2019_Toxicol.Lett_321_83
Author(s) : Macek Hrvat N , Kalisiak J , Sinko G , Radic Z , Sharpless KB , Taylor P , Kovarik Z
Ref : Toxicol Lett , 321 :83 , 2019
PubMedID: 31863869

Title : Reversal of Tabun Toxicity Enabled by a Triazole-Annulated Oxime Library-Reactivators of Acetylcholinesterase - Kovarik_2019_Chemistry_25_4100
Author(s) : Kovarik Z , Kalisiak J , Hrvat NM , Katalinic M , Zorbaz T , Zunec S , Green C , Radic Z , Fokin VV , Sharpless KB , Taylor P
Ref : Chemistry , 25 :4100 , 2019
PubMedID: 30458057

Title : A new crystal form of human acetylcholinesterase for exploratory room-temperature crystallography studies - Gerlits_2019_Chem.Biol.Interact_13ChEPon_
Author(s) : Gerlits O , Ho KY , Cheng X , Blumenthal D , Taylor P , Kovalevsky A , Radic Z
Ref : Chemico-Biological Interactions , : , 2019
PubMedID: 31176713
Gene_locus related to this paper: human-ACHE

Title : Productive reorientation of a bound oxime reactivator revealed in room temperature X-ray structures of native and VX-inhibited human acetylcholinesterase - Gerlits_2019_J.Biol.Chem_294_10607
Author(s) : Gerlits O , Kong X , Cheng X , Wymore T , Blumenthal DK , Taylor P , Radic Z , Kovalevsky A
Ref : Journal of Biological Chemistry , 294 :10607 , 2019
PubMedID: 31138650
Gene_locus related to this paper: human-ACHE

Title : Assessment of ionizable, zwitterionic oximes as reactivating antidotal agents for organophosphate exposure - Taylor_2019_Chem.Biol.Interact_13ChEPon_308_194
Author(s) : Taylor P , Yan-Jye S , Momper J , Hou W , Camacho-Hernandez GA , Radic Z , Rosenberg YJ , Kovarik Z , Sit R , Sharpless KB
Ref : Chemico-Biological Interactions , 308 :194 , 2019
PubMedID: 31100277

Title : Counteracting tabun inhibition by reactivation by pyridinium aldoximes that interact with active center gorge mutants of acetylcholinesterase - Kovarik_2019_Toxicol.Appl.Pharmacol_372_40
Author(s) : Kovarik Z , Macek Hrvat N , Kalisiak J , Katalinic M , Sit RK , Zorbaz T , Radic Z , Fokin VV , Sharpless KB , Taylor P
Ref : Toxicol Appl Pharmacol , 372 :40 , 2019
PubMedID: 30978400
Gene_locus related to this paper: human-ACHE

Title : Pharmacology, Pharmacokinetics, and Tissue Disposition of Zwitterionic Hydroxyiminoacetamido Alkylamines as Reactivating Antidotes for Organophosphate Exposure - Sit_2018_J.Pharmacol.Exp.Ther_367_363
Author(s) : Sit RK , Kovarik Z , Macek Hrvat N , Zunec S , Green C , Fokin VV , Sharpless KB , Radic Z , Taylor P
Ref : Journal of Pharmacology & Experimental Therapeutics , 367 :363 , 2018
PubMedID: 30190337

Title : Planarian cholinesterase: molecular and functional characterization of an evolutionarily ancient enzyme to study organophosphorus pesticide toxicity - Hagstrom_2018_Arch.Toxicol_92_1161
Author(s) : Hagstrom D , Zhang S , Ho A , Tsai ES , Radic Z , Jahromi A , Kaj KJ , He Y , Taylor P , Collins ES
Ref : Archives of Toxicology , 92 :1161 , 2018
PubMedID: 29167930
Gene_locus related to this paper: dugja-CHE1 , dugja-CHE2

Title : Cyclic imine toxins from dinoflagellates: a growing family of potent antagonists of the nicotinic acetylcholine receptors - Molgo_2017_J.Neurochem_142 Suppl 2_41
Author(s) : Molgo J , Marchot P , Araoz R , Benoit E , Iorga BI , Zakarian A , Taylor P , Bourne Y , Servent D
Ref : Journal of Neurochemistry , 142 Suppl 2 :41 , 2017
PubMedID: 28326551

Title : Butyrylcholinesterase identification in a phenylvalerate esterase-enriched fraction sensitive to low mipafox concentrations in chicken brain - Mangas_2017_Arch.Toxicol_91_909
Author(s) : Mangas I , Radic Z , Taylor P , Ghassemian M , Candela H , Vilanova E , Estevez J
Ref : Archives of Toxicology , 91 :909 , 2017
PubMedID: 26838044

Title : Post-exposure treatment with the oxime RS194B rapidly reactivates and reverses advanced symptoms of lethal inhaled paraoxon in macaques - Rosenberg_2018_Toxicol.Lett_293_229
Author(s) : Rosenberg YJ , Wang J , Ooms T , Rajendran N , Mao L , Jiang X , Lees J , Urban L , Romper J , Sepulveda Y , Shyong YJ , Taylor P
Ref : Toxicol Lett , 293 :229 , 2017
PubMedID: 29129799

Title : Post-exposure treatment with the oxime RS194B rapidly reverses early and advanced symptoms in macaques exposed to sarin vapor - Rosenberg_2017_Chem.Biol.Interact_274_50
Author(s) : Rosenberg YJ , Mao L , Jiang X , Lees J , Zhang L , Radic Z , Taylor P
Ref : Chemico-Biological Interactions , 274 :50 , 2017
PubMedID: 28693885

Title : HI-6 assisted catalytic scavenging of VX by acetylcholinesterase choline binding site mutants - Macek Hrvat_2016_Chem.Biol.Interact_259_148
Author(s) : Macek Hrvat N , Zunec S , Taylor P , Radic Z , Kovarik Z
Ref : Chemico-Biological Interactions , 259 :148 , 2016
PubMedID: 27083141
Gene_locus related to this paper: human-ACHE

Title : Limitations in current acetylcholinesterase structure-based design of oxime antidotes for organophosphate poisoning - Kovalevsky_2016_Ann.N.Y.Acad.Sci_1378_41
Author(s) : Kovalevsky A , Blumenthal DK , Cheng X , Taylor P , Radic Z
Ref : Annals of the New York Academy of Sciences , 1378 :41 , 2016
PubMedID: 27371941

Title : Planarian cholinesterase: in vitro characterization of an evolutionarily ancient enzyme to study organophosphorus pesticide toxicity and reactivation - Hagstrom_2017_Arch.Toxicol_91_2837
Author(s) : Hagstrom D , Hirokawa H , Zhang L , Radic Z , Taylor P , Collins ES
Ref : Archives of Toxicology , 91 :2837 , 2016
PubMedID: 27990564
Gene_locus related to this paper: dugja-CHE1 , dugja-CHE2

Title : Mechanistic studies of new oximes reactivators of human butyrylcholinesterase inhibited by cyclosarin and sarin - de Lima_2016_J.Biomol.Struct.Dyn__1
Author(s) : de Lima WE , Francisco A , da Cunha EFF , Radic Z , Taylor P , Franca TCC , Ramalho TC
Ref : J Biomol Struct Dyn , :1 , 2016
PubMedID: 27125569

Title : Resolving pathways of interaction of mipafox and a sarin analog with human acetylcholinesterase by kinetics, mass spectrometry and molecular modeling approaches - Mangas_2016_Arch.Toxicol_90_603
Author(s) : Mangas I , Taylor P , Vilanova E , Estevez J , Franca TCC , Komives E , Radic Z
Ref : Archives of Toxicology , 90 :603 , 2016
PubMedID: 25743373

Title : Steric and Dynamic Parameters Influencing In Situ Cycloadditions to Form Triazole Inhibitors with Crystalline Acetylcholinesterase - Bourne_2016_J.Am.Chem.Soc_138_1611
Author(s) : Bourne Y , Sharpless KB , Taylor P , Marchot P
Ref : Journal of the American Chemical Society , 138 :1611 , 2016
PubMedID: 26731630
Gene_locus related to this paper: mouse-ACHE

Title : Quaternary and tertiary aldoxime antidotes for organophosphate exposure in a zebrafish model system - Schmidt_2015_Toxicol.Appl.Pharmacol_284_197
Author(s) : Schmidt HR , Radic Z , Taylor P , Fradinger EA
Ref : Toxicol Appl Pharmacol , 284 :197 , 2015
PubMedID: 25701203

Title : Cognitive Improvements in a Mouse Model with Substituted 1,2,3-Triazole Agonists for Nicotinic Acetylcholine Receptors - Arunrungvichian_2015_ACS.Chem.Neurosci_6_1331
Author(s) : Arunrungvichian K , Boonyarat C , Fokin VV , Taylor P , Vajragupta O
Ref : ACS Chem Neurosci , 6 :1331 , 2015
PubMedID: 25978789

Title : Catalytic Soman Scavenging by the Y337A\/F338A Acetylcholinesterase Mutant Assisted with Novel Site-Directed Aldoximes - Kovarik_2015_Chem.Res.Toxicol_28_1036
Author(s) : Kovarik Z , Macek Hrvat N , Katalinic M , Sit RK , Paradyse A , Zunec S , Musilek K , Fokin VV , Taylor P , Radic Z
Ref : Chemical Research in Toxicology , 28 :1036 , 2015
PubMedID: 25835984

Title : Marine Macrocyclic Imines, Pinnatoxins A and G: Structural Determinants and Functional Properties to Distinguish Neuronal alpha7 from Muscle alpha1(2)betagammadelta nAChRs - Bourne_2015_Structure_23_1106
Author(s) : Bourne Y , Sulzenbacher G , Radic Z , Araoz R , Reynaud M , Benoit E , Zakarian A , Servent D , Molgo J , Taylor P , Marchot P
Ref : Structure , 23 :1106 , 2015
PubMedID: 26004441

Title : Imidazole aldoximes effective in assisting butyrylcholinesterase catalysis of organophosphate detoxification - Sit_2014_J.Med.Chem_57_1378
Author(s) : Sit RK , Fokin VV , Amitai G , Sharpless KB , Taylor P , Radic Z
Ref : Journal of Medicinal Chemistry , 57 :1378 , 2014
PubMedID: 24571195

Title : Centrally acting oximes in reactivation of tabun-phosphoramidated AChE - Kovarik_2013_Chem.Biol.Interact_203_77
Author(s) : Kovarik Z , Macek Hrvat N , Sit RK , Radic Z , Fokin VV , Sharpless KB , Taylor P
Ref : Chemico-Biological Interactions , 203 :77 , 2013
PubMedID: 22960624

Title : Catalytic detoxification of nerve agent and pesticide organophosphates by butyrylcholinesterase assisted with non-pyridinium oximes - Radic_2013_Biochem.J_450_231
Author(s) : Radic Z , Dale T , Kovarik Z , Zunec S , Garcia E , Zhang LM , Amitai G , Green C , Radic B , Duggan BM , Ajami D , Rebek J , Taylor P
Ref : Biochemical Journal , 450 :231 , 2013
PubMedID: 23216060

Title : Automated docking with protein flexibility in the design of femtomolar click chemistry inhibitors of acetylcholinesterase - Morris_2013_J.Chem.Inf.Model_53_898
Author(s) : Morris GM , Green LG , Radic Z , Taylor P , Sharpless KB , Olson AJ , Grynszpan F
Ref : J Chem Inf Model , 53 :898 , 2013
PubMedID: 23451944

Title : Cholinesterase confabs and cousins: Approaching forty years - Taylor_2013_Chem.Biol.Interact_203_10
Author(s) : Taylor P , De Jaco A , Comoletti D , Miller M , Camp S
Ref : Chemico-Biological Interactions , 203 :10 , 2013
PubMedID: 23085121

Title : Mechanism of interaction of novel uncharged, centrally active reactivators with OP-hAChE conjugates - Radic_2013_Chem.Biol.Interact_203_67
Author(s) : Radic Z , Sit RK , Garcia E , Zhang LM , Zunec S , Kovarik Z , Amitai G , Fokin VV , Sharpless KB , Taylor P
Ref : Chemico-Biological Interactions , 203 :67 , 2013
PubMedID: 22975155

Title : Refinement of structural leads for centrally acting oxime reactivators of phosphylated cholinesterases - Radic_2012_J.Biol.Chem_287_11798
Author(s) : Radic Z , Sit RK , Kovarik Z , Zunec S , Garcia E , Zhang L , Amitai G , Green C , Radic B , Fokin VV , Sharpless KB , Taylor P
Ref : Journal of Biological Chemistry , 287 :11798 , 2012
PubMedID: 22343626

Title : Synthesis of selective agonists for the alpha7 nicotinic acetylcholine receptor with in situ click-chemistry on acetylcholine-binding protein templates - Yamauchi_2012_Mol.Pharmacol_82_687
Author(s) : Yamauchi JG , Gomez K , Grimster N , Dufouil M , Nemecz A , Fotsing JR , Ho KY , Talley TT , Sharpless KB , Fokin VV , Taylor P
Ref : Molecular Pharmacology , 82 :687 , 2012
PubMedID: 22784805

Title : Transcellular neuroligin-2 interactions enhance insulin secretion and are integral to pancreatic beta cell function - Suckow_2012_J.Biol.Chem_287_19816
Author(s) : Suckow AT , Zhang C , Egodage S , Comoletti D , Taylor P , Miller MT , Sweet IR , Chessler SD
Ref : Journal of Biological Chemistry , 287 :19816 , 2012
PubMedID: 22528485

Title : Congenital hypothyroidism mutations affect common folding and trafficking in the alpha\/beta-hydrolase fold proteins - De Jaco_2012_Febs.J_279_4293
Author(s) : De Jaco A , Dubi N , Camp S , Taylor P
Ref : Febs J , 279 :4293 , 2012
PubMedID: 23035660
Gene_locus related to this paper: human-TG

Title : Processing of cholinesterase-like alpha\/beta-hydrolase fold proteins: alterations associated with congenital disorders - De Jaco_2012_Protein.Pept.Lett_19_173
Author(s) : De Jaco A , Comoletti D , Dubi N , Camp S , Taylor P
Ref : Protein Pept Lett , 19 :173 , 2012
PubMedID: 21933121

Title : Generation of candidate ligands for nicotinic acetylcholine receptors via in situ click chemistry with a soluble acetylcholine binding protein template - Grimster_2012_J.Am.Chem.Soc_134_6732
Author(s) : Grimster NP , Stump B , Fotsing JR , Weide T , Talley TT , Yamauchi JG , Nemecz A , Kim C , Ho KY , Sharpless KB , Taylor P , Fokin VV
Ref : Journal of the American Chemical Society , 134 :6732 , 2012
PubMedID: 22394239

Title : Characterizing ligand-gated ion channel receptors with genetically encoded Ca2++ sensors - Yamauchi_2011_PLoS.One_6_e16519
Author(s) : Yamauchi JG , Nemecz A , Nguyen QT , Muller A , Schroeder LF , Talley TT , Lindstrom JM , Kleinfeld D , Taylor P
Ref : PLoS ONE , 6 :e16519 , 2011
PubMedID: 21305050

Title : New structural scaffolds for centrally acting oxime reactivators of phosphylated cholinesterases - Sit_2011_J.Biol.Chem_286_19422
Author(s) : Sit RK , Radic Z , Gerardi V , Zhang L , Garcia E , Katalinic M , Amitai G , Kovarik Z , Fokin VV , Sharpless KB , Taylor P
Ref : Journal of Biological Chemistry , 286 :19422 , 2011
PubMedID: 21464125

Title : Distinct localization of collagen Q and PRiMA forms of acetylcholinesterase at the neuromuscular junction - Bernard_2011_Mol.Cell.Neurosci_46_272
Author(s) : Bernard V , Girard E , Hrabovska A , Camp S , Taylor P , Plaud B , Krejci E
Ref : Molecular & Cellular Neurosciences , 46 :272 , 2011
PubMedID: 20883790

Title : Docking studies of benzylidene anabaseine interactions with alpha7 nicotinic acetylcholine receptor (nAChR) and acetylcholine binding proteins (AChBPs): application to the design of related alpha7 selective ligands - Kombo_2011_Eur.J.Med.Chem_46_5625
Author(s) : Kombo DC , Mazurov A , Tallapragada K , Hammond PS , Chewning J , Hauser TA , Vasquez-Valdivieso M , Yohannes D , Talley TT , Taylor P , Caldwell WS
Ref : Eur Journal of Medicinal Chemistry , 46 :5625 , 2011
PubMedID: 21986237

Title : Oxime-assisted acetylcholinesterase catalytic scavengers of organophosphates that resist aging - Cochran_2011_J.Biol.Chem_286_29718
Author(s) : Cochran R , Kalisiak J , Kucukkilinc TT , Radic Z , Garcia E , Zhang L , Ho KY , Amitai G , Kovarik Z , Fokin VV , Sharpless KB , Taylor P
Ref : Journal of Biological Chemistry , 286 :29718 , 2011
PubMedID: 21730071

Title : Naturally occurring variations in the human cholinesterase genes: heritability and association with cardiovascular and metabolic traits - Valle_2011_J.Pharmacol.Exp.Ther_338_125
Author(s) : Valle AM , Radic Z , Rana BK , Mahboubi V , Wessel J , Shih PA , Rao F , O'Connor DT , Taylor P
Ref : Journal of Pharmacology & Experimental Therapeutics , 338 :125 , 2011
PubMedID: 21493754

Title : Poster: Acetylcholine binding protein-nicotinic receptor chimeras for delineating structure and determinants of ligand selectivity -
Author(s) : Talley TT , Nemecz A , Yamauchi JG , Wu J , Ho KY , Sankaran B , Taylor P
Ref : Biochemical Pharmacology , 82 :1028 , 2011
PubMedID:

Title : Cis and trans actions of the cholinesterase-like domain within the thyroglobulin dimer - Wang_2010_J.Biol.Chem_285_17564
Author(s) : Wang X , Lee J , Di Jeso B , Treglia AS , Comoletti D , Dubi N , Taylor P , Arvan P
Ref : Journal of Biological Chemistry , 285 :17564 , 2010
PubMedID: 20353937

Title : An in vivo biosensor for neurotransmitter release and in situ receptor activity - Nguyen_2010_Nat.Neurosci_13_127
Author(s) : Nguyen QT , Schroeder LF , Mank M , Muller A , Taylor P , Griesbeck O , Kleinfeld D
Ref : Nat Neurosci , 13 :127 , 2010
PubMedID: 20010818

Title : Interaction kinetics of oximes with native, phosphylated and aged human acetylcholinesterase - Radic_2010_Chem.Biol.Interact_187_163
Author(s) : Radic Z , Kalisiak J , Fokin VV , Sharpless KB , Taylor P
Ref : Chemico-Biological Interactions , 187 :163 , 2010
PubMedID: 20412789

Title : Folding anomalies of neuroligin3 caused by a mutation in the alpha\/beta-hydrolase fold domain - De Jaco_2010_Chem.Biol.Interact_187_56
Author(s) : De Jaco A , Dubi N , Comoletti D , Taylor P
Ref : Chemico-Biological Interactions , 187 :56 , 2010
PubMedID: 20227402

Title : Investigating the structural influence of surface mutations on acetylcholinesterase inhibition by organophosphorus compounds and oxime reactivation - Kucukkilinc_2010_Chem.Biol.Interact_187_238
Author(s) : Kucukkilinc TT , Cochran R , Kalisiak J , Garcia E , Valle A , Amitai G , Radic Z , Taylor P
Ref : Chemico-Biological Interactions , 187 :238 , 2010
PubMedID: 20382137

Title : Structure-function relationships of the alpha\/beta-hydrolase fold domain of neuroligin: a comparison with acetylcholinesterase - Leone_2010_Chem.Biol.Interact_187_49
Author(s) : Leone P , Comoletti D , Taylor P , Bourne Y , Marchot P
Ref : Chemico-Biological Interactions , 187 :49 , 2010
PubMedID: 20100470

Title : Structural determinants in phycotoxins and AChBP conferring high affinity binding and nicotinic AChR antagonism - Bourne_2010_Proc.Natl.Acad.Sci.U.S.A_107_6076
Author(s) : Bourne Y , Radic Z , Araoz R , Talley TT , Benoit E , Servent D , Taylor P , Molgo J , Marchot P
Ref : Proc Natl Acad Sci U S A , 107 :6076 , 2010
PubMedID: 20224036

Title : Contributions of selective knockout studies to understanding cholinesterase disposition and function - Camp_2010_Chem.Biol.Interact_187_72
Author(s) : Camp S , Zhang L , Krejci E , Dobbertin A , Bernard V , Girard E , Duysen EG , Lockridge O , De Jaco A , Taylor P
Ref : Chemico-Biological Interactions , 187 :72 , 2010
PubMedID: 20153304

Title : From Split to Sibenik: The Tortuous Pathway in the Cholinesterase Field - Taylor_2010_Chem.Biol.Interact_187_3
Author(s) : Taylor P
Ref : Chemico-Biological Interactions , 187 :3 , 2010
PubMedID: 20493179

Title : Structural insights into the exquisite selectivity of neurexin\/neuroligin synaptic interactions - Leone_2010_EMBO.J_29_2461
Author(s) : Leone P , Comoletti D , Ferracci G , Conrod S , Garcia SU , Taylor P , Bourne Y , Marchot P
Ref : EMBO Journal , 29 :2461 , 2010
PubMedID: 20543817
Gene_locus related to this paper: human-NLGN4X

Title : Conformational remodeling of femtomolar inhibitor-acetylcholinesterase complexes in the crystalline state - Bourne_2010_J.Am.Chem.Soc_132_18292
Author(s) : Bourne Y , Radic Z , Taylor P , Marchot P
Ref : Journal of the American Chemical Society , 132 :18292 , 2010
PubMedID: 21090615
Gene_locus related to this paper: mouse-ACHE

Title : On the origin of ion selectivity in the Cys-loop receptor family - Sine_2010_J.Mol.Neurosci_40_70
Author(s) : Sine SM , Wang HL , Hansen S , Taylor P
Ref : Journal of Molecular Neuroscience , 40 :70 , 2010
PubMedID: 19728176

Title : Neuroligin trafficking deficiencies arising from mutations in the alpha\/beta-hydrolase fold protein family - De Jaco_2010_J.Biol.Chem_285_28674
Author(s) : De Jaco A , Lin MZ , Dubi N , Comoletti D , Miller MT , Camp S , Ellisman M , Butko MT , Tsien RY , Taylor P
Ref : Journal of Biological Chemistry , 285 :28674 , 2010
PubMedID: 20615874
Gene_locus related to this paper: ratno-3neur , ratno-1neur

Title : A virtual screening study of the acetylcholine binding protein using a relaxed-complex approach - Babakhani_2009_Comput.Biol.Chem_33_160
Author(s) : Babakhani A , Talley TT , Taylor P , McCammon JA
Ref : Comput Biol Chem , 33 :160 , 2009
PubMedID: 19186108

Title : Nicotinic agonist binding site mapped by methionine- and tyrosine-scanning coupled with azidochloropyridinyl photoaffinity labeling - Tomizawa_2009_J.Med.Chem_52_3735
Author(s) : Tomizawa M , Talley TT , Park JF , Maltby D , Medzihradszky KF , Durkin KA , Cornejo-Bravo JM , Burlingame AL , Casida JE , Taylor P
Ref : Journal of Medicinal Chemistry , 52 :3735 , 2009
PubMedID: 19459645

Title : Structural determinants for interaction of partial agonists with acetylcholine binding protein and neuronal alpha7 nicotinic acetylcholine receptor - Hibbs_2009_EMBO.J_28_3040
Author(s) : Hibbs RE , Sulzenbacher G , Shi J , Talley TT , Conrod S , Kem WR , Taylor P , Marchot P , Bourne Y
Ref : EMBO Journal , 28 :3040 , 2009
PubMedID: 19696737

Title : Natural variation within the neuronal nicotinic acetylcholine receptor cluster on human chromosome 15q24: influence on heritable autonomic traits in twin pairs - Rana_2009_J.Pharmacol.Exp.Ther_331_419
Author(s) : Rana BK , Wessel J , Mahboubi V , Rao F , Haeller J , Gayen JR , Eskin E , Valle AM , Das M , Mahata SK , Taupenot L , Stridsberg M , Talley TT , Ziegler MG , Smith DW , Schork NJ , O'Connor DT , Taylor P
Ref : Journal of Pharmacology & Experimental Therapeutics , 331 :419 , 2009
PubMedID: 19671882

Title : Influence of differential expression of acetylcholinesterase in brain and muscle on respiration - Boudinot_2009_Respir.Physiol.Neurobiol_165_40
Author(s) : Boudinot E , Bernard V , Camp S , Taylor P , Champagnat J , Krejci E , Foutz AS
Ref : Respir Physiol Neurobiol , 165 :40 , 2009
PubMedID: 18977317

Title : Acetylcholinesterase expression in muscle is specifically controlled by a promoter-selective enhancesome in the first intron - Camp_2008_J.Neurosci_28_2459
Author(s) : Camp S , De Jaco A , Zhang L , Marquez M , de la Torre B , Taylor P
Ref : Journal of Neuroscience , 28 :2459 , 2008
PubMedID: 18322091

Title : Atomic interactions of neonicotinoid agonists with AChBP: molecular recognition of the distinctive electronegative pharmacophore - Talley_2008_Proc.Natl.Acad.Sci.U.S.A_105_7606
Author(s) : Talley TT , Harel M , Hibbs RE , Radic Z , Tomizawa M , Casida JE , Taylor P
Ref : Proc Natl Acad Sci U S A , 105 :7606 , 2008
PubMedID: 18477694

Title : The cholinesterases: analysis by pharmacogenomics in man - Valle_2008_Chem.Biol.Interact_175_343
Author(s) : Valle AM , Radic Z , Rana BK , Whitfield JB , O'Connor DT , Martin NG , Taylor P
Ref : Chemico-Biological Interactions , 175 :343 , 2008
PubMedID: 18541229

Title : Characterization of the solution structure of a neuroligin\/beta-neurexin complex - Comoletti_2008_Chem.Biol.Interact_175_150
Author(s) : Comoletti D , Grishaev A , Whitten AE , Taylor P , Trewhella J
Ref : Chemico-Biological Interactions , 175 :150 , 2008
PubMedID: 18550038

Title : Expression of neurexin, neuroligin, and their cytoplasmic binding partners in the pancreatic beta-cells and the involvement of neuroligin in insulin secretion - Suckow_2008_Endocrinology_149_6006
Author(s) : Suckow AT , Comoletti D , Waldrop MA , Mosedale M , Egodage S , Taylor P , Chessler SD
Ref : Endocrinology , 149 :6006 , 2008
PubMedID: 18755801
Gene_locus related to this paper: human-NLGN1

Title : Control of cation permeation through the nicotinic receptor channel - Wang_2008_PLoS.Comput.Biol_4_e41
Author(s) : Wang HL , Cheng X , Taylor P , McCammon JA , Sine SM
Ref : PLoS Comput Biol , 4 :e41 , 2008
PubMedID: 18282090

Title : Trafficking of cholinesterases and neuroligins mutant proteins. An association with autism - De Jaco_2008_Chem.Biol.Interact_175_349
Author(s) : De Jaco A , Comoletti D , King CC , Taylor P
Ref : Chemico-Biological Interactions , 175 :349 , 2008
PubMedID: 18555979

Title : Probing gorge dimensions of cholinesterases by freeze-frame click chemistry - Radic_2008_Chem.Biol.Interact_175_161
Author(s) : Radic Z , Manetsch R , Fournier D , Sharpless KB , Taylor P
Ref : Chemico-Biological Interactions , 175 :161 , 2008
PubMedID: 18555981

Title : An ion selectivity filter in the extracellular domain of Cys-loop receptors reveals determinants for ion conductance - Hansen_2008_J.Biol.Chem_283_36066
Author(s) : Hansen SB , Wang HL , Taylor P , Sine SM
Ref : Journal of Biological Chemistry , 283 :36066 , 2008
PubMedID: 18940802

Title : Synaptic arrangement of the neuroligin\/beta-neurexin complex revealed by X-ray and neutron scattering - Comoletti_2007_Structure_15_693
Author(s) : Comoletti D , Grishaev A , Whitten AE , Tsigelny I , Taylor P , Trewhella J
Ref : Structure , 15 :693 , 2007
PubMedID: 17562316
Gene_locus related to this paper: human-NLGN3 , human-NLGN4X

Title : Application of recombinant DNA methods for production of cholinesterases as organophosphate antidotes and detectors - Taylor_2007_Arh.Hig.Rada.Toksikol_58_339
Author(s) : Taylor P , Reiner E , Kovarik Z , Radic Z
Ref : Arh Hig Rada Toksikol , 58 :339 , 2007
PubMedID: 17913689

Title : Structure-guided drug design: conferring selectivity among neuronal nicotinic receptor and acetylcholine-binding protein subtypes - Taylor_2007_Biochem.Pharmacol_74(8)_1164
Author(s) : Taylor P , Talley TT , Radic Z , Hansen SB , Hibbs RE , Shi J
Ref : Biochemical Pharmacology , 74 :1164 , 2007
PubMedID: 17826748

Title : Acetylcholinesterase: converting a vulnerable target to a template for antidotes and detection of inhibitor exposure - Taylor_2007_Toxicology_233_70
Author(s) : Taylor P , Kovarik Z , Reiner E , Radic Z
Ref : Toxicology , 233 :70 , 2007
PubMedID: 17196318

Title : Defining nicotinic agonist binding surfaces through photoaffinity labeling - Tomizawa_2007_Biochemistry_46_8798
Author(s) : Tomizawa M , Maltby D , Medzihradszky KF , Zhang N , Durkin KA , Presley J , Talley TT , Taylor P , Burlingame AL , Casida JE
Ref : Biochemistry , 46 :8798 , 2007
PubMedID: 17614369

Title : Mapping the elusive neonicotinoid binding site - Tomizawa_2007_Proc.Natl.Acad.Sci.U.S.A_104_9075
Author(s) : Tomizawa M , Talley TT , Maltby D , Durkin KA , Medzihradszky KF , Burlingame AL , Taylor P , Casida JE
Ref : Proc Natl Acad Sci U S A , 104 :9075 , 2007
PubMedID: 17485662

Title : Structural analysis of the synaptic protein neuroligin and its beta-neurexin complex: determinants for folding and cell adhesion - Fabrichny_2007_Neuron_56_979
Author(s) : Fabrichny IP , Leone P , Sulzenbacher G , Comoletti D , Miller MT , Taylor P , Bourne Y , Marchot P
Ref : Neuron , 56 :979 , 2007
PubMedID: 18093521
Gene_locus related to this paper: human-NLGN4X

Title : Mutation of acetylcholinesterase to enhance oxime-assisted catalytic turnover of methylphosphonates - Kovarik_2007_Toxicology_233_79
Author(s) : Kovarik Z , Radic Z , Berman HA , Taylor P
Ref : Toxicology , 233 :79 , 2007
PubMedID: 17046138

Title : Butyrylcholinesterase: association with the metabolic syndrome and identification of 2 gene loci affecting activity - Valle_2006_Clin.Chem_52_1014
Author(s) : Valle A , O'Connor DT , Taylor P , Zhu G , Montgomery GW , Slagboom PE , Martin NG , Whitfield JB
Ref : Clinical Chemistry , 52 :1014 , 2006
PubMedID: 16574762

Title : Active site mutant acetylcholinesterase interactions with 2-PAM, HI-6, and DDVP - Kovarik_2006_Biochem.Biophys.Res.Commun_342_973
Author(s) : Kovarik Z , Ciban N , Radic Z , Simeon-Rudolf V , Taylor P
Ref : Biochemical & Biophysical Research Communications , 342 :973 , 2006
PubMedID: 16598855

Title : Remodeling of the neuromuscular junction in mice with deleted exons 5 and 6 of acetylcholinesterase - Girard_2006_J.Mol.Neurosci_30_99
Author(s) : Girard E , Bernard V , Camp S , Taylor P , Krejci E , Molgo J
Ref : Journal of Molecular Neuroscience , 30 :99 , 2006
PubMedID: 17192646

Title : Gene selection, alternative splicing, and post-translational processing regulate neuroligin selectivity for beta-neurexins - Comoletti_2006_Biochemistry_45_12816
Author(s) : Comoletti D , Flynn RE , Boucard AA , Demeler B , Schirf V , Shi J , Jennings LL , Newlin HR , Sudhof TC , Taylor P
Ref : Biochemistry , 45 :12816 , 2006
PubMedID: 17042500

Title : Structural characterization of agonist and antagonist-bound acetylcholine-binding protein from Aplysia californica - Hansen_2006_J.Mol.Neurosci_30_101
Author(s) : Hansen SB , Sulzenbacher G , Huxford T , Marchot P , Bourne Y , Taylor P
Ref : Journal of Molecular Neuroscience , 30 :101 , 2006
PubMedID: 17192647

Title : A mutation linked with autism reveals a common mechanism of endoplasmic reticulum retention for the alpha,beta-hydrolase fold protein family - De Jaco_2006_J.Biol.Chem_281_9667
Author(s) : De Jaco A , Comoletti D , Kovarik Z , Gaietta G , Radic Z , Lockridge O , Ellisman MH , Taylor P
Ref : Journal of Biological Chemistry , 281 :9667 , 2006
PubMedID: 16434405

Title : Structural comparison of three crystalline complexes of a peptidic toxin with a synaptic acetylcholine recognition protein - Bourne_2006_J.Mol.Neurosci_30_103
Author(s) : Bourne Y , Hansen SB , Sulzenbacher G , Talley TT , Huxford T , Taylor P , Marchot P
Ref : Journal of Molecular Neuroscience , 30 :103 , 2006
PubMedID: 17192648

Title : Solution NMR of acetylcholine binding protein reveals agonist-mediated conformational change of the C-loop - Gao_2006_Mol.Pharmacol_70_1230
Author(s) : Gao F , Mer G , Tonelli M , Hansen SB , Burghardt TP , Taylor P , Sine SM
Ref : Molecular Pharmacology , 70 :1230 , 2006
PubMedID: 16847142

Title : Structural dynamics of the acetylcholine binding protein: hydrodynamic and fluorescence anisotropy decay analyses - Hibbs_2006_J.Mol.Neurosci_30_73
Author(s) : Hibbs RE , Johnson DA , Shi J , Taylor P
Ref : Journal of Molecular Neuroscience , 30 :73 , 2006
PubMedID: 17192634

Title : Synaptic efficacy and remodeling at the neuromuscular junction of knockout mice deficient in acetylcholinesterase -
Author(s) : Girard E , Barbier J , Camp S , Taylor P , Chatonnet A , Krejci E , Molgo J
Ref : Journal de Physiologie (Paris) , 99 :254 , 2006
PubMedID:

Title : Substrate and product trafficking through the active center gorge of acetylcholinesterase analyzed by crystallography and equilibrium binding - Bourne_2006_J.Biol.Chem_281_29256
Author(s) : Bourne Y , Radic Z , Sulzenbacher G , Kim E , Taylor P , Marchot P
Ref : Journal of Biological Chemistry , 281 :29256 , 2006
PubMedID: 16837465
Gene_locus related to this paper: mouse-ACHE

Title : Conformational transitions in protein-protein association: binding of fasciculin-2 to acetylcholinesterase - Bui_2006_Biophys.J_90_3280
Author(s) : Bui JM , Radic Z , Taylor P , McCammon JA
Ref : Biophysical Journal , 90 :3280 , 2006
PubMedID: 16473897

Title : Influence of agonists and antagonists on the segmental motion of residues near the agonist binding pocket of the acetylcholine-binding protein - Hibbs_2006_J.Biol.Chem_281_39708
Author(s) : Hibbs RE , Radic Z , Taylor P , Johnson DA
Ref : Journal of Biological Chemistry , 281 :39708 , 2006
PubMedID: 17068341

Title : Ligand-induced conformational change in the alpha7 nicotinic receptor ligand binding domain - Henchman_2005_Biophys.J_88_2564
Author(s) : Henchman RH , Wang HL , Sine SM , Taylor P , McCammon JA
Ref : Biophysical Journal , 88 :2564 , 2005
PubMedID: 15665135

Title : In situ selection of lead compounds by click chemistry: target-guided optimization of acetylcholinesterase inhibitors - Krasinski_2005_J.Am.Chem.Soc_127_6686
Author(s) : Krasinski A , Radic Z , Manetsch R , Raushel J , Taylor P , Sharpless KB , Kolb HC
Ref : Journal of the American Chemical Society , 127 :6686 , 2005
PubMedID: 15869290

Title : Tetrameric mouse acetylcholinesterase: continuum diffusion rate calculations by solving the steady-state Smoluchowski equation using finite element methods - Zhang_2005_Biophys.J_88_1659
Author(s) : Zhang D , Suen J , Zhang Y , Song Y , Radic Z , Taylor P , Holst MJ , Bajaj C , Baker NA , McCammon JA
Ref : Biophysical Journal , 88 :1659 , 2005
PubMedID: 15626705

Title : Molecular basis of interactions of cholinesterases with tight binding inhibitors - Radic_2005_Chem.Biol.Interact_157-158_133
Author(s) : Radic Z , Manetsch R , Krasinski A , Raushel J , Yamauchi J , Garcia C , Kolb HC , Sharpless KB , Taylor P
Ref : Chemico-Biological Interactions , 157-158 :133 , 2005
PubMedID: 16289416

Title : Acetylcholinesterase (AChE) gene modification in transgenic animals: functional consequences of selected exon and regulatory region deletion - Camp_2005_Chem.Biol.Interact_157-158_79
Author(s) : Camp S , Zhang L , Marquez M , de la Torre B , Long JM , Bucht G , Taylor P
Ref : Chemico-Biological Interactions , 157-158 :79 , 2005
PubMedID: 16289062

Title : Influence of the 5' intron in the control of acetylcholinesterase gene expression during myogenesis - De Jaco_2005_Chem.Biol.Interact_157-158_372
Author(s) : De Jaco A , Camp S , Taylor P
Ref : Chemico-Biological Interactions , 157-158 :372 , 2005
PubMedID: 16429497

Title : A single mutation near the C-terminus in alpha\/beta hydrolase fold protein family causes a defect in protein processing - De Jaco_2005_Chem.Biol.Interact_157-158_371
Author(s) : De Jaco A , Kovarik Z , Comoletti D , Jennings LL , Gaietta G , Ellisman MH , Taylor P
Ref : Chemico-Biological Interactions , 157-158 :371 , 2005
PubMedID: 16429495

Title : A splice code for trans-synaptic cell adhesion mediated by binding of neuroligin 1 to alpha- and beta-neurexins - Boucard_2005_Neuron_48_229
Author(s) : Boucard AA , Chubykin AA , Comoletti D , Taylor P , Sudhof TC
Ref : Neuron , 48 :229 , 2005
PubMedID: 16242404

Title : Agonist-mediated conformational changes in acetylcholine-binding protein revealed by simulation and intrinsic tryptophan fluorescence - Gao_2005_J.Biol.Chem_280_8443
Author(s) : Gao F , Bren N , Burghardt TP , Hansen S , Henchman RH , Taylor P , McCammon JA , Sine SM
Ref : Journal of Biological Chemistry , 280 :8443 , 2005
PubMedID: 15591050

Title : Dissection of synapse induction by neuroligins: effect of a neuroligin mutation associated with autism - Chubykin_2005_J.Biol.Chem_280_22365
Author(s) : Chubykin AA , Liu X , Comoletti D , Tsigelny I , Taylor P , Sudhof TC
Ref : Journal of Biological Chemistry , 280 :22365 , 2005
PubMedID: 15797875

Title : Species-related differences in the oxime-induced reactivation of organophosphate-inhibited acetylcholinesterases -
Author(s) : Luo C , Dawson M , Chambers C , Chilukuri N , Radic Z , Taylor P , Doctor BP , Saxena A
Ref : Chemico-Biological Interactions , 157-158 :393 , 2005
PubMedID: 16429528

Title : Structural insights into conformational flexibility at the peripheral site and within the active center gorge of AChE - Bourne_2005_Chem.Biol.Interact_157-158_159
Author(s) : Bourne Y , Radic Z , Kolb HC , Sharpless KB , Taylor P , Marchot P
Ref : Chemico-Biological Interactions , 157-158 :159 , 2005
PubMedID: 16259971

Title : Structural dynamics of the alpha-neurotoxin-acetylcholine-binding protein complex: hydrodynamic and fluorescence anisotropy decay analyses - Hibbs_2005_Biochemistry_44_16602
Author(s) : Hibbs RE , Johnson DA , Shi J , Hansen SB , Taylor P
Ref : Biochemistry , 44 :16602 , 2005
PubMedID: 16342951

Title : Acetylcholinesterase mutants: oxime-assisted catalytic scavengers of organophosphonates -
Author(s) : Kovarik Z , Radic Z , Simeon-Rudolf V , Reiner E , Taylor P
Ref : Chemico-Biological Interactions , 157-158 :388 , 2005
PubMedID: 16429526

Title : Ligand-induced conformational changes in residues flanking the active site gorge of acetylcholinesterase -
Author(s) : Pezzementi L , Shi J , Johnson DA , Radic Z , Boyd A , Taylor P
Ref : Chemico-Biological Interactions , 157-158 :413 , 2005
PubMedID: 16429560

Title : Contemporary paradigms for cholinergic ligand design guided by biological structure - Taylor_2004_Bioorg.Med.Chem.Lett_14_1875
Author(s) : Taylor P , Hansen SB , Talley TT , Hibbs RE , Radic Z
Ref : Bioorganic & Medicinal Chemistry Lett , 14 :1875 , 2004
PubMedID: 15050619

Title : The Arg451Cys-neuroligin-3 mutation associated with autism reveals a defect in protein processing - Comoletti_2004_J.Neurosci_24_4889
Author(s) : Comoletti D , De Jaco A , Jennings LL , Flynn RE , Gaietta G , Tsigelny I , Ellisman MH , Taylor P
Ref : Journal of Neuroscience , 24 :4889 , 2004
PubMedID: 15152050

Title : Poster (50) Insights into the interactions at the acetylcholinesterase peripheral anionic site. -
Author(s) : Bourne Y , Taylor P , Radic Z , Berman HA , Marchot P
Ref : In: Cholinesterases in the Second Millennium: Biomolecular and Pathological Aspects , (Inestrosa NC, Campos EO) P. Universidad Catolica de Chile-FONDAP Biomedicina :347 , 2004
PubMedID:

Title : Poster (51) Novel compounds with distinctive interactions at the acetylcholinesterase peripheral anionic site -
Author(s) : Bourne Y , Taylor P , Radic Z , Lewis WG , Grynszpan F , Finn MG , Sharpless KB , Marchot P
Ref : In: Cholinesterases in the Second Millennium: Biomolecular and Pathological Aspects , (Inestrosa NC, Campos EO) P. Universidad Catolica de Chile-FONDAP Biomedicina :348 , 2004
PubMedID:

Title : Rene Couteaux Lecture. -
Author(s) : Taylor P
Ref : Cholinergic Mechanisms, CRC Press :81 , 2004
PubMedID:

Title : Mutant cholinesterases possessing enhanced capacity for reactivation of their phosphonylated conjugates - Kovarik_2004_Biochemistry_43_3222
Author(s) : Kovarik Z , Radic Z , Berman HA , Simeon-Rudolf V , Reiner E , Taylor P
Ref : Biochemistry , 43 :3222 , 2004
PubMedID: 15023072

Title : Two possible orientations of the HI-6 molecule in the reactivation of organophosphate-inhibited acetylcholinesterase. -
Author(s) : Luo C , Leader H , Radic Z , Maxwell DM , Taylor P , Doctor BP , Saxena A
Ref : Cholinergic Mechanisms, CRC Press :627 , 2004
PubMedID:

Title : Interaction of recombinant soluble neuroligin-1 with neurexin-1-_. -
Author(s) : Comoletti D , Flynn RE , Jennings LL , Hoffman RC , Marchot P , Bourne Y , Sudhof TC , Taylor P
Ref : Cholinergic Mechanisms, CRC Press :523 , 2004
PubMedID:

Title : Nanosecond dynamics of acetylcholinesterase near the active center gorge - Boyd_2004_J.Biol.Chem_279_26612
Author(s) : Boyd AE , Dunlop CS , Wong L , Radic Z , Taylor P , Johnson DA
Ref : Journal of Biological Chemistry , 279 :26612 , 2004
PubMedID: 15078872

Title : Knockout mice with deletions of alternatively spliced exons of acetylcholinesterase -
Author(s) : Camp S , Zhang LM , Marquez M , de la Torre B , Taylor P
Ref : In: Cholinesterases in the Second Millennium: Biomolecular and Pathological Aspects , (Inestrosa NC, Campos EO) P. Universidad Catolica de Chile-FONDAP Biomedicina :43 , 2004
PubMedID:

Title : Coupling of agonist binding to channel gating in an ACh-binding protein linked to an ion channel - Bouzat_2004_Nature_430_896
Author(s) : Bouzat C , Gumilar F , Spitzmaul G , Wang HL , Rayes D , Hansen SB , Taylor P , Sine SM
Ref : Nature , 430 :896 , 2004
PubMedID: 15318223

Title : Kinetics of interaction of ethopropazine enantiomers with butyrylcholinesterase and acetylcholinesterase. -
Author(s) : Reiner E , Sinko G , Radic Z , Taylor P , Simeon-Rudolf V
Ref : Cholinergic Mechanisms, CRC Press :705 , 2004
PubMedID:

Title : Poster (85) Organophosphate modifications of mouse acetylcholinesterase: detection of exposure by maldi-tof mass spectrometry -
Author(s) : Jennings LL , Komives EA , Taylor P
Ref : In: Cholinesterases in the Second Millennium: Biomolecular and Pathological Aspects , (Inestrosa NC, Campos EO) P. Universidad Catolica de Chile-FONDAP Biomedicina :365 , 2004
PubMedID:

Title : Poster (89) Phosphorylation of mouse cholinesterases and mutants by ddvp and reactivation of conjugates by Hi-6 and 2-PAM -
Author(s) : Kovarik Z , Wong L , Radic Z , Taylor P
Ref : In: Cholinesterases in the Second Millennium: Biomolecular and Pathological Aspects , (Inestrosa NC, Campos EO) P. Universidad Catolica de Chile-FONDAP Biomedicina :367 , 2004
PubMedID:

Title : Freeze-frame inhibitor captures acetylcholinesterase in a unique conformation - Bourne_2004_Proc.Natl.Acad.Sci.U.S.A_101_1449
Author(s) : Bourne Y , Kolb HC , Radic Z , Sharpless KB , Taylor P , Marchot P
Ref : Proc Natl Acad Sci U S A , 101 :1449 , 2004
PubMedID: 14757816
Gene_locus related to this paper: mouse-ACHE

Title : Intrinsic tryptophan fluorescence of cholinesterases. -
Author(s) : Radic Z , Kim E , Taylor P
Ref : Cholinergic Mechanisms, CRC Press :171 , 2004
PubMedID:

Title : Phosphonylation of acetylcholinesterase and the propensity for reactivation analysed by chirality and mutagenesis. -
Author(s) : Kovarik Z , Radic Z , Berman HA , Taylor P
Ref : Cholinergic Mechanisms, CRC Press :611 , 2004
PubMedID:

Title : Poster (10) Knockout mice with deletions of alternatively spliced exons of acetylcholinesterase. -
Author(s) : Camp S , Zhang LM , Marquez M , Taylor P
Ref : In: Cholinesterases in the Second Millennium: Biomolecular and Pathological Aspects , (Inestrosa NC, Campos EO) P. Universidad Catolica de Chile-FONDAP Biomedicina :326 , 2004
PubMedID:

Title : Poster (13) Conformational dynamics accompanying substrate and inhibitor binding to acetylcholinesterase. -
Author(s) : Taylor P , Shi J , Johnson DA , Boyd AE , Radic Z
Ref : In: Cholinesterases in the Second Millennium: Biomolecular and Pathological Aspects , (Inestrosa NC, Campos EO) P. Universidad Catolica de Chile-FONDAP Biomedicina :327 , 2004
PubMedID:

Title : Spectroscopic approaches to the study of acetylcholinesterase structure and function -
Author(s) : Taylor P , Shi J , Radic Z , Boyd AE , Johnson DA
Ref : In: Cholinesterases in the Second Millennium: Biomolecular and Pathological Aspects , (Inestrosa NC, Campos EO) P. Universidad Catolica de Chile-FONDAP Biomedicina :177 , 2004
PubMedID:

Title : Kinetics of ethopropazine binding to butyrylcholinesterase in the absence and presence of acetylthiocholine -
Author(s) : Reiner E , Sinko G , Bosak A , Simeon-Rudolf V , Radic Z , Taylor P , Stojan J , Golicnik M
Ref : In: Cholinesterases in the Second Millennium: Biomolecular and Pathological Aspects , (Inestrosa NC, Campos EO) P. Universidad Catolica de Chile-FONDAP Biomedicina :187 , 2004
PubMedID:

Title : Monitoring cholinesterase - ligand interactions -
Author(s) : Radic Z , Kim E , Taylor P
Ref : In: Cholinesterases in the Second Millennium: Biomolecular and Pathological Aspects , (Inestrosa NC, Campos EO) P. Universidad Catolica de Chile-FONDAP Biomedicina :201 , 2004
PubMedID:

Title : Poster (105) Analysis of acetylcholinesterase structure and dynamics by steady state and time-resolved fluorescence -
Author(s) : Shi J , Radic Z , Johnson DA , Taylor P
Ref : In: Cholinesterases in the Second Millennium: Biomolecular and Pathological Aspects , (Inestrosa NC, Campos EO) P. Universidad Catolica de Chile-FONDAP Biomedicina :375 , 2004
PubMedID:

Title : Ligand-induced conformational changes in the omega loop of acetylcholinesterase revealed by fluorescence spectroscopy. -
Author(s) : Shi J , Radic Z , Boyd AE , Johnson DA , Taylor P
Ref : Cholinergic Mechanisms, CRC Press :695 , 2004
PubMedID:

Title : Poster (19) Kinetics of ethopropazine binding to butyrylcholinesterase in the absence and presence of acetylthiocholine. -
Author(s) : Reiner E , Sinko G , Stuglin A , Simeon-Rudolf V , Radic Z , Taylor P , Stojan J , Golicnik M
Ref : In: Cholinesterases in the Second Millennium: Biomolecular and Pathological Aspects , (Inestrosa NC, Campos EO) P. Universidad Catolica de Chile-FONDAP Biomedicina :330 , 2004
PubMedID:

Title : Phosphorylation of mouse cholinesterases and mutants by DDVP and reactivation of conjugates by HI-6 and 2-PAM -
Author(s) : Kovarik Z , Wong L , Radic Z , Taylor P
Ref : In: Cholinesterases in the Second Millennium: Biomolecular and Pathological Aspects , (Inestrosa NC, Campos EO) P. Universidad Catolica de Chile-FONDAP Biomedicina :219 , 2004
PubMedID:

Title : In situ click chemistry: enzyme inhibitors made to their own specifications - Manetsch_2004_J.Am.Chem.Soc_126_12809
Author(s) : Manetsch R , Krasinski A , Radic Z , Raushel J , Taylor P , Sharpless KB , Kolb HC
Ref : Journal of the American Chemical Society , 126 :12809 , 2004
PubMedID: 15469276

Title : Structural characterization of recombinant soluble rat neuroligin 1: mapping of secondary structure and glycosylation by mass spectrometry - Hoffman_2004_Biochemistry_43_1496
Author(s) : Hoffman RC , Jennings LL , Tsigelny I , Comoletti D , Flynn RE , Sudhof TC , Taylor P
Ref : Biochemistry , 43 :1496 , 2004
PubMedID: 14769026
Gene_locus related to this paper: ratno-1neur

Title : Acrylodan-conjugated cysteine side chains reveal conformational state and ligand site locations of the acetylcholine-binding protein - Hibbs_2004_J.Biol.Chem_279_28483
Author(s) : Hibbs RE , Talley TT , Taylor P
Ref : Journal of Biological Chemistry , 279 :28483 , 2004
PubMedID: 15117947

Title : Poster (22) Monitoring cholinesterase-ligand interactions -
Author(s) : Radic Z , Taylor P
Ref : In: Cholinesterases in the Second Millennium: Biomolecular and Pathological Aspects , (Inestrosa NC, Campos EO) P. Universidad Catolica de Chile-FONDAP Biomedicina :332 , 2004
PubMedID:

Title : Analysis of acetylcholinesterase structure and dynamics by steady state and time-resolved fluorescence -
Author(s) : Shi J , Radic Z , Johnson DA , Taylor P
Ref : In: Cholinesterases in the Second Millennium: Biomolecular and Pathological Aspects , (Inestrosa NC, Campos EO) P. Universidad Catolica de Chile-FONDAP Biomedicina :225 , 2004
PubMedID:

Title : Organophosphate modifications of mouse acetylcholinesterase: Detection of exposure by Maldi-Tof mass spectrometry -
Author(s) : Jennings LL , Komives EA , Taylor P
Ref : In: Cholinesterases in the Second Millennium: Biomolecular and Pathological Aspects , (Inestrosa NC, Campos EO) P. Universidad Catolica de Chile-FONDAP Biomedicina :265 , 2004
PubMedID:

Title : Two possible orientations of the HI-6 molecule in the reactivation of organophosphate-inhibited acetylcholinesterase - Luo_2003_Biochem.Pharmacol_66_387
Author(s) : Luo C , Leader H , Radic Z , Maxwell DM , Taylor P , Doctor BP , Saxena A
Ref : Biochemical Pharmacology , 66 :387 , 2003
PubMedID: 12907237

Title : Asymmetric structural motions of the homomeric alpha7 nicotinic receptor ligand binding domain revealed by molecular dynamics simulation - Henchman_2003_Biophys.J_85_3007
Author(s) : Henchman RH , Wang HL , Sine SM , Taylor P , McCammon JA
Ref : Biophysical Journal , 85 :3007 , 2003
PubMedID: 14581202

Title : Characterization of the interaction of a recombinant soluble neuroligin-1 with neurexin-1beta - Comoletti_2003_J.Biol.Chem_278_50497
Author(s) : Comoletti D , Flynn RE , Jennings LL , Chubykin AA , Matsumura T , Hasegawa H , Sudhof TC , Taylor P
Ref : Journal of Biological Chemistry , 278 :50497 , 2003
PubMedID: 14522992

Title : Acetylcholinesterase active centre and gorge conformations analyzed by combinatorial mutations and enantiomeric phosphonates - Kovarik_2003_Biochem.J_373_33
Author(s) : Kovarik Z , Radic Z , Berman HA , Simeon-Rudolf V , Reiner E , Taylor P
Ref : Biochemical Journal , 31 :33 , 2003
PubMedID: 12665427

Title : Direct analysis of the kinetic profiles of organophosphate-acetylcholinesterase adducts by MALDI-TOF mass spectrometry - Jennings_2003_Biochemistry_42_11083
Author(s) : Jennings LL , Malecki M , Komives EA , Taylor P
Ref : Biochemistry , 42 :11083 , 2003
PubMedID: 12974645

Title : Aromatic amino-acid residues at the active and peripheral anionic sites control the binding of E2020 (Aricept) to cholinesterases - Saxena_2003_Eur.J.Biochem_270_4447
Author(s) : Saxena A , Fedorko JM , Vinayaka CR , Medhekar R , Radic Z , Taylor P , Lockridge O , Doctor BP
Ref : European Journal of Biochemistry , 270 :4447 , 2003
PubMedID: 14622273

Title : Nanosecond dynamics of the mouse acetylcholinesterase cys69-cys96 omega loop - Shi_2003_J.Biol.Chem_278_30905
Author(s) : Shi J , Tai K , McCammon JA , Taylor P , Johnson DA
Ref : Journal of Biological Chemistry , 278 :30905 , 2003
PubMedID: 12759360

Title : Curariform antagonists bind in different orientations to acetylcholine-binding protein - Gao_2003_J.Biol.Chem_278_23020
Author(s) : Gao F , Bern N , Little A , Wang HL , Hansen SB , Talley TT , Taylor P , Sine SM
Ref : Journal of Biological Chemistry , 278 :23020 , 2003
PubMedID: 12682067

Title : Differentiation between acetylcholinesterase and the organophosphate-inhibited form using antibodies and the correlation of antibody recognition with reactivation mechanism and rate - George_2003_J.Biol.Chem_278_45512
Author(s) : George KM , Schule T , Sandoval LE , Jennings LL , Taylor P , Thompson CM
Ref : Journal of Biological Chemistry , 278 :45512 , 2003
PubMedID: 12933813

Title : Structural insights into ligand interactions at the acetylcholinesterase peripheral anionic site - Bourne_2003_Embo.J_22_1
Author(s) : Bourne Y , Taylor P , Radic Z , Marchot P
Ref : EMBO Journal , 22 :1 , 2003
PubMedID: 12505979
Gene_locus related to this paper: mouse-ACHE

Title : Expression, purification, crystallization and preliminary crystallographic analysis of a thermostable lipase from Bacillus stearothermophilus P1 - Sinchaikul_2002_Acta.Crystallogr.D.Biol.Crystallogr_58_182
Author(s) : Sinchaikul S , Tyndall JD , Fothergill-Gilmore LA , Taylor P , Phutrakul S , Chen ST , Walkinshaw MD
Ref : Acta Crystallographica D Biol Crystallogr , 58 :182 , 2002
PubMedID: 11752807
Gene_locus related to this paper: geost-lipas

Title : Inhibitors of different structure induce distinguishing conformations in the omega loop, Cys 69- Cys 96, of mouse acetylcholinesterase - Shi_2002_J.Biol.Chem_277_43301
Author(s) : Shi J , Radic Z , Taylor P
Ref : Journal of Biological Chemistry , 277 :43301 , 2002
PubMedID: 12196517

Title : Current progress on esterases: from molecular structure to function - Satoh_2002_Drug.Metab.Dispos_30_488
Author(s) : Satoh T , Taylor P , Bosron WF , Sanghani SP , Hosokawa M , La Du BN
Ref : Drug Metabolism & Disposition: The Biological Fate of Chemicals , 30 :488 , 2002
PubMedID: 11950776

Title : Crystal Structure of a Thermostable Lipase from Bacillus stearothermophilus P1 - Tyndall_2002_J.Mol.Biol_323_859
Author(s) : Tyndall JD , Sinchaikul S , Fothergill-Gilmore LA , Taylor P , Walkinshaw MD
Ref : Journal of Molecular Biology , 323 :859 , 2002
PubMedID: 12417199
Gene_locus related to this paper: geost-lipas

Title : Identification of residues at the alpha and epsilon subunit interfaces mediating species selectivity of Waglerin-1 for nicotinic acetylcholine receptors - Molles_2002_J.Biol.Chem_277_5433
Author(s) : Molles BE , Rezai P , Kline EF , McArdle JJ , Sine SM , Taylor P
Ref : Journal of Biological Chemistry , 277 :5433 , 2002
PubMedID: 11724791

Title : Residues in the epsilon subunit of the nicotinic acetylcholine receptor interact to confer selectivity of waglerin-1 for the alpha-epsilon subunit interface site - Molles_2002_Biochemistry_41_7895
Author(s) : Molles BE , Tsigelny I , Nguyen PD , Gao SX , Sine SM , Taylor P
Ref : Biochemistry , 41 :7895 , 2002
PubMedID: 12069578

Title : Cover picture: angew. Chem. Int. Ed. 6\/2002 - Lewis_2002_Angew.Chem.Int.Ed.Engl_41_875
Author(s) : Lewis WG , Green LG , Grynszpan F , Radic Z , Carlier PR , Taylor P , Finn MG , Sharpless KB
Ref : Angew Chem Int Ed Engl , 41 :875 , 2002
PubMedID:

Title : Click chemistry in situ: acetylcholinesterase as a reaction vessel for the selective assembly of a femtomolar inhibitor from an array of building blocks -
Author(s) : Lewis WG , Green LG , Grynszpan F , Radic Z , Carlier PR , Taylor P , Finn MG , Sharpless KB
Ref : Angew Chem Int Ed Engl , 41 :1053 , 2002
PubMedID: 12491310

Title : Tryptophan fluorescence reveals conformational changes in the acetylcholine binding protein - Hansen_2002_J.Biol.Chem_277_41299
Author(s) : Hansen SB , Radic Z , Talley TT , Molles BE , Deerinck TJ , Tsigelny I , Taylor P
Ref : Journal of Biological Chemistry , 277 :41299 , 2002
PubMedID: 12235129

Title : Reversibly bound and covalently attached ligands induce conformational changes in the Omega loop, Cys 69-Cys 96, of mouse acetylcholinesterase - Shi_2001_J.Biol.Chem_276_42196
Author(s) : Shi J , Boyd AE , Radic Z , Taylor P
Ref : Journal of Biological Chemistry , 276 :42196 , 2001
PubMedID: 11517229

Title : Peripheral site ligands accelerate inhibition of acetylcholinesterase by neutral organophosphates - Radic_2001_J.Appl.Toxicol_21 Suppl 1_S13
Author(s) : Radic Z , Taylor P
Ref : J Appl Toxicol , 21 Suppl 1 :S13 , 2001
PubMedID: 11920914

Title : Pairwise electrostatic interactions between alpha-neurotoxins and gamma, delta, and epsilon subunits of the nicotinic acetylcholine receptor - Osaka_2000_J.Biol.Chem_275_5478
Author(s) : Osaka H , Malany S , Molles BE , Sine SM , Taylor P
Ref : Journal of Biological Chemistry , 275 :5478 , 2000
PubMedID: 10681526

Title : Synthesis of fluorescent probes directed to the active site gorge of acetylcholinesterase - Saltmarsh_2000_Bioorg.Med.Chem.Lett_10_1523
Author(s) : Saltmarsh JR , Boyd AE , Rodriguez OP , Radic Z , Taylor P , Thompson CM
Ref : Bioorganic & Medicinal Chemistry Lett , 10 :1523 , 2000
PubMedID: 10915041

Title : Orientation of alpha-neurotoxin at the subunit interfaces of the nicotinic acetylcholine receptor - Malany_2000_Biochemistry_39_15388
Author(s) : Malany S , Osaka H , Sine SM , Taylor P
Ref : Biochemistry , 39 :15388 , 2000
PubMedID: 11112524

Title : Contributions of Studies of the Nicotinic Receptor from Muscle to Defining Structural and Functional Properties of Ligand-Gated Ion Channels -
Author(s) : Taylor P , Osaka H , Molles BE , Keller SH , Malany S
Ref : Handbook of Experimental Pharmacology , 144 :79 , 2000
PubMedID:

Title : Probing the active center Gorge of acetylcholinesterase by fluorophores Linked to substituted cysteines - Boyd_2000_J.Biol.Chem_275_22401
Author(s) : Boyd AE , Marnett AB , Wong L , Taylor P
Ref : Journal of Biological Chemistry , 275 :22401 , 2000
PubMedID: 10779503

Title : Mechanism of oxime reactivation of acetylcholinesterase analyzed by chirality and mutagenesis - Wong_2000_Biochemistry_39_5750
Author(s) : Wong L , Radic Z , Bruggemann RJ , Hosea NA , Berman HA , Taylor P
Ref : Biochemistry , 39 :5750 , 2000
PubMedID: 10801325

Title : Postnatal developmental delay and supersensitivity to organophosphate in gene-targeted mice lacking acetylcholinesterase - Xie_2000_J.Pharmacol.Exp.Ther_293_896
Author(s) : Xie W , Stribley JA , Chatonnet A , Wilder PJ , Rizzino A , McComb RD , Taylor P , Hinrichs SH , Lockridge O
Ref : Journal of Pharmacology & Experimental Therapeutics , 293 :896 , 2000
PubMedID: 10869390
Gene_locus related to this paper: mouse-ACHE

Title : Common EF-hand motifs in cholinesterases and neuroligins suggest a role for Ca2+ binding in cell surface associations - Tsigelny_2000_Protein.Sci_9_180
Author(s) : Tsigelny I , Shindyalov IN , Bourne PE , Sudhof TC , Taylor P
Ref : Protein Science , 9 :180 , 2000
PubMedID: 10739260

Title : Inactivation studies of acetylcholinesterase with phenylmethylsulfonyl fluoride - Kraut_2000_Mol.Pharmacol_57_1243
Author(s) : Kraut D , Goff H , Pai RK , Hosea NA , Silman I , Sussman JL , Taylor P , Voet JG
Ref : Molecular Pharmacology , 57 :1243 , 2000
PubMedID: 10825396

Title : Subunit interface selective toxins as probes of nicotinic acetylcholine receptor structure - Taylor_2000_Pflugers.Arch_440_R115
Author(s) : Taylor P , Malanz S , Molles BE , Osaka H , Tsigelny I
Ref : Pflugers Arch , 440 :R115 , 2000
PubMedID: 11005635

Title : Subunit interface selectivity of the alpha-neurotoxins for the nicotinic acetylcholine receptor - Osaka_1999_J.Biol.Chem_274_9581
Author(s) : Osaka H , Malany S , Kanter J , Sine SM , Taylor P
Ref : Journal of Biological Chemistry , 274 :9581 , 1999
PubMedID: 10092644

Title : The influence of peripheral site ligands on the reaction of symmetric and chiral organophosphates with wildtype and mutant acetylcholinesterases - Radic_1999_Chem.Biol.Interact_119-120_111
Author(s) : Radic Z , Taylor P
Ref : Chemico-Biological Interactions , 119-120 :111 , 1999
PubMedID: 10421444

Title : Knockout of one acetylcholinesterase allele in the mouse - Xie_1999_Chem.Biol.Interact_119-120_289
Author(s) : Xie W , Wilder PJ , Stribley J , Chatonnet A , Rizzino A , Taylor P , Hinrichs SH , Lockridge O
Ref : Chemico-Biological Interactions , 119-120 :289 , 1999
PubMedID: 10421464

Title : Role of edrophonium in prevention of the re-inhibition of acetylcholinesterase by phosphorylated oxime - Luo_1999_Chem.Biol.Interact_119-120_129
Author(s) : Luo C , Saxena A , Ashani Y , Leader H , Radic Z , Taylor P , Doctor BP
Ref : Chemico-Biological Interactions , 119-120 :129 , 1999
PubMedID: 10421446

Title : Analysis of cholinesterase inactivation and reactivation by systematic structural modification and enantiomeric selectivity - Taylor_1999_Chem.Biol.Interact_119-120_3
Author(s) : Taylor P , Wong L , Radic Z , Tsigelny I , Bruggemann R , Hosea NA , Berman HA
Ref : Chemico-Biological Interactions , 119-120 :3 , 1999
PubMedID: 10421434

Title : International Union of Pharmacology. XX. Current status of the nomenclature for nicotinic acetylcholine receptors and their subunits -
Author(s) : Lukas RJ , Changeux JP , Le Novere N , Albuquerque EX , Balfour DJ , Berg DK , Bertrand D , Chiappinelli VA , Clarke PB , Collins AC , Dani JA , Grady SR , Kellar KJ , Lindstrom JM , Marks MJ , Quik M , Taylor P , Wonnacott S
Ref : Pharmacol Rev , 51 :397 , 1999
PubMedID: 10353988

Title : Crystal structure of mouse acetylcholinesterase. A peripheral site- occluding loop in a tetrameric assembly - Bourne_1999_J.Biol.Chem_274_2963
Author(s) : Bourne Y , Taylor P , Bougis PE , Marchot P
Ref : Journal of Biological Chemistry , 274 :2963 , 1999
PubMedID: 9915834
Gene_locus related to this paper: mouse-ACHE

Title : Calcineurin enhances acetylcholinesterase mRNA stability during C2-C12 muscle cell differentiation - Luo_1999_Mol.Pharmacol_56_886
Author(s) : Luo ZD , Wang Y , Werlen G , Camp S , Chien KR , Taylor P
Ref : Molecular Pharmacology , 56 :886 , 1999
PubMedID: 10531391

Title : Phosphoryl oxime inhibition of acetylcholinesterase during oxime reactivation is prevented by edrophonium - Luo_1999_Biochemistry_38_9937
Author(s) : Luo C , Saxena A , Smith M , Garcia GE , Radic Z , Taylor P , Doctor BP
Ref : Biochemistry , 38 :9937 , 1999
PubMedID: 10433700

Title : Complementary binding studies between alpha-neurotoxin and the nicotinic acetylcholine receptor -
Author(s) : Malany S , Ackermann EJ , Osaka H , Taylor P
Ref : Journal de Physiologie (Paris) , 92 :462 , 1998
PubMedID:

Title : Rapid binding of a cationic active site inhibitor to wild type and mutant mouse acetylcholinesterase: Brownian dynamics simulation including diffusion in the active site gorge - Tara_1998_Biopolymers_46_465
Author(s) : Tara S , Elcock AH , Kirchhoff PD , Briggs JM , Radic Z , Taylor P , McCammon JA
Ref : Biopolymers , 46 :465 , 1998
PubMedID: 9838872

Title : Tetrameric assembly and peripheral site-occluding loop of mouse acetylcholinesterase -
Author(s) : Marchot P , Taylor P , Kanter J , Bougis PE , Bourne Y
Ref : Journal de Physiologie (Paris) , 92 :465 , 1998
PubMedID:

Title : Probing the structure of the ligand binding site on the muscle nicotinic receptor with Waglerin peptides -
Author(s) : Molles BE , Kline EF , Sine SM , McArdle JJ , Taylor P
Ref : Journal de Physiologie (Paris) , 92 :470 , 1998
PubMedID:

Title : Crystal Structure of Mouse Acetylcholinesterase -
Author(s) : Bourne Y , Taylor P , Kanter J , Bougis PE , Marchot P
Ref : In: Structure and Function of Cholinesterases and Related Proteins - Proceedings of Sixth International Meeting on Cholinesterases , (Doctor, B.P., Taylor, P., Quinn, D.M., Rotundo, R.L., Gentry, M.K. Eds) Plenum Publishing Corp. :315 , 1998
PubMedID:

Title : Fasciculin Inhibition of Mouse Acetylcholinesterase -
Author(s) : Marchot P , Bourne Y , Prowse CN , Kanter J , Eads J , Bougis PE , Taylor P
Ref : In: Structure and Function of Cholinesterases and Related Proteins - Proceedings of Sixth International Meeting on Cholinesterases , (Doctor, B.P., Taylor, P., Quinn, D.M., Rotundo, R.L., Gentry, M.K. Eds) Plenum Publishing Corp. :331 , 1998
PubMedID:

Title : Binding orientation of thealpha-neurotoxins with the nicotinic acetylcholine receptor -
Author(s) : Osaka H , Ackermann EJ , Kanter J , Tsigelny I , Sine SM , Taylor P
Ref : Journal de Physiologie (Paris) , 92 :476 , 1998
PubMedID:

Title : ACHE Knockout Mouse\; Cat AChE and Cat BChE Sequences\; Tetramers of BChE -
Author(s) : Lockridge O , Xie W , Chatonnet A , Taylor P , Bartels CF
Ref : In: Structure and Function of Cholinesterases and Related Proteins - Proceedings of Sixth International Meeting on Cholinesterases , (Doctor, B.P., Taylor, P., Quinn, D.M., Rotundo, R.L., Gentry, M.K. Eds) Plenum Publishing Corp. :41 , 1998
PubMedID:

Title : Splicing of 5' introns dictates alternative splice selection of acetylcholinesterase pre-mRNA and specific expression during myogenesis - Luo_1998_J.Biol.Chem_273_28486
Author(s) : Luo ZD , Camp S , Mutero A , Taylor P
Ref : Journal of Biological Chemistry , 273 :28486 , 1998
PubMedID: 9774478

Title : Oxime Reactivation of Acetylcholinesterase Inhibited by Enantiomeric Organophosphates -
Author(s) : Bruggemann RJ , Radic Z , Tsigelny I , Taylor P
Ref : In: Structure and Function of Cholinesterases and Related Proteins - Proceedings of Sixth International Meeting on Cholinesterases , (Doctor, B.P., Taylor, P., Quinn, D.M., Rotundo, R.L., Gentry, M.K. Eds) Plenum Publishing Corp. :377 , 1998
PubMedID:

Title : Metal Binding Motifs in Cholinesterases and Neuroligins -
Author(s) : Tsigelny I , Matsumura T , Sudhof TC , Taylor P
Ref : In: Structure and Function of Cholinesterases and Related Proteins - Proceedings of Sixth International Meeting on Cholinesterases , (Doctor, B.P., Taylor, P., Quinn, D.M., Rotundo, R.L., Gentry, M.K. Eds) Plenum Publishing Corp. :407 , 1998
PubMedID:

Title : Intronic Sequences Influence Pre-mRNA Splicing of Acetylcholinesterase During Muscle Differentiation -
Author(s) : Luo ZD , Camp S , Mutero A , Taylor P
Ref : In: Structure and Function of Cholinesterases and Related Proteins - Proceedings of Sixth International Meeting on Cholinesterases , (Doctor, B.P., Taylor, P., Quinn, D.M., Rotundo, R.L., Gentry, M.K. Eds) Plenum Publishing Corp. :121 , 1998
PubMedID:

Title : Calcineurin Enhances mRNA Stability of Acetylcholinesterase During Muscle Differentiation in C2-C12 Cells -
Author(s) : Luo ZD , Wang Y , Taylor P
Ref : In: Structure and Function of Cholinesterases and Related Proteins - Proceedings of Sixth International Meeting on Cholinesterases , (Doctor, B.P., Taylor, P., Quinn, D.M., Rotundo, R.L., Gentry, M.K. Eds) Plenum Publishing Corp. :123 , 1998
PubMedID:

Title : Inhibition of mouse acetylcholinesterase by fasciculin: crystal structure of the complex and mutagenesis of fasciculin - Marchot_1998_Toxicon_36_1613
Author(s) : Marchot P , Bourne Y , Prowse CN , Bougis PE , Taylor P
Ref : Toxicon , 36 :1613 , 1998
PubMedID: 9792178

Title : Biotinylation of the tyrosine residues of fasciculin -
Author(s) : Bougis PE , Taylor P , Marchot P
Ref : Journal de Physiologie (Paris) , 92 :416 , 1998
PubMedID:

Title : Acetylcholinesterase Structural Perturbations Examined Through Cysteine Substitution Mutagenesis -
Author(s) : Boyd AE , Wong L , Taylor P
Ref : In: Structure and Function of Cholinesterases and Related Proteins - Proceedings of Sixth International Meeting on Cholinesterases , (Doctor, B.P., Taylor, P., Quinn, D.M., Rotundo, R.L., Gentry, M.K. Eds) Plenum Publishing Corp. :452 , 1998
PubMedID:

Title : The Effect of Peripheral Site Ligands on the Reaction Kinetics of Phosphyl and Carboxyl Esters with Acetylcholinesterase -
Author(s) : Radic Z , Taylor P
Ref : In: Structure and Function of Cholinesterases and Related Proteins - Proceedings of Sixth International Meeting on Cholinesterases , (Doctor, B.P., Taylor, P., Quinn, D.M., Rotundo, R.L., Gentry, M.K. Eds) Plenum Publishing Corp. :211 , 1998
PubMedID:

Title : Acceleration of Oxime-Induced Reactivation of Organophosphate-Inhibited Acetylcholinesterase by Quaternary Ligands -
Author(s) : Luo C , Ashani Y , Saxena A , Leader H , Maxwell DM , Taylor P , Doctor BP
Ref : In: Structure and Function of Cholinesterases and Related Proteins - Proceedings of Sixth International Meeting on Cholinesterases , (Doctor, B.P., Taylor, P., Quinn, D.M., Rotundo, R.L., Gentry, M.K. Eds) Plenum Publishing Corp. :215 , 1998
PubMedID:

Title : Correlation of Isotope and Viscosity Effects -
Author(s) : Malany S , Taylor P , Quinn DM , Sawai M , Shafferman A , Velan B , Kronman C
Ref : In: Structure and Function of Cholinesterases and Related Proteins - Proceedings of Sixth International Meeting on Cholinesterases , (Doctor, B.P., Taylor, P., Quinn, D.M., Rotundo, R.L., Gentry, M.K. Eds) Plenum Publishing Corp. :232 , 1998
PubMedID:

Title : Residues at the subunit interfaces of the nicotinic acetylcholine receptor that contribute to alpha-conotoxin M1 binding - Sugiyama_1998_Mol.Pharmacol_53_787
Author(s) : Sugiyama N , Marchot P , Kawanishi C , Osaka H , Molles BE , Sine SM , Taylor P
Ref : Molecular Pharmacology , 53 :787 , 1998
PubMedID: 9547372

Title : Expression and Purification of Recombinant Mutants of Fasciculin from Mammalian Cells -
Author(s) : Kanter J , Eads J , Camp S , Marchot P , Taylor P
Ref : In: Structure and Function of Cholinesterases and Related Proteins - Proceedings of Sixth International Meeting on Cholinesterases , (Doctor, B.P., Taylor, P., Quinn, D.M., Rotundo, R.L., Gentry, M.K. Eds) Plenum Publishing Corp. :240 , 1998
PubMedID:

Title : Intronic Elements Appear Essential for the Differentiation-Specific Expression of Acetylcholinesterase in C2C12 Myotubes -
Author(s) : Camp S , Taylor P
Ref : In: Structure and Function of Cholinesterases and Related Proteins - Proceedings of Sixth International Meeting on Cholinesterases , (Doctor, B.P., Taylor, P., Quinn, D.M., Rotundo, R.L., Gentry, M.K. Eds) Plenum Publishing Corp. :51 , 1998
PubMedID:

Title : Mechanisms regulating expression of nicotinic acetylcholine receptor subunits -
Author(s) : Keller SH , Taylor P
Ref : Journal de Physiologie (Paris) , 92 :446 , 1998
PubMedID:

Title : Development of acetylcholinesterase inhibitors in the therapy of Alzheimer's disease - Taylor_1998_Neurology_51_S65
Author(s) : Taylor P
Ref : Neurology , 51 :S65 , 1998
PubMedID: 9674760

Title : Reactivation of Enantiomeric Organophosphonyl Conjugates of Acetylcholinesterase Mutants, F295L and F297I by Mono- and Bis-Quarternary Oximes -
Author(s) : Wong L , Radic Z , Hosea NA , Berman HA , Taylor P
Ref : In: Structure and Function of Cholinesterases and Related Proteins - Proceedings of Sixth International Meeting on Cholinesterases , (Doctor, B.P., Taylor, P., Quinn, D.M., Rotundo, R.L., Gentry, M.K. Eds) Plenum Publishing Corp. :250 , 1998
PubMedID:

Title : Toxins selective for subunit interfaces as probes of nicotinic acetylcholine receptor structure - Taylor_1998_J.Physiol.Paris_92_79
Author(s) : Taylor P , Osaka H , Molles BE , Sugiyama N , Marchot P , Ackermann EJ , Malany S , McArdle JJ , Sine SM , Tsigelny I
Ref : Journal de Physiologie (Paris) , 92 :79 , 1998
PubMedID: 9782448

Title : A model of the nicotinic receptor extracellular domain based on sequence identity and residue location - Tsigelny_1997_Biophys.J_73_52
Author(s) : Tsigelny I , Sugiyama N , Sine SM , Taylor P
Ref : Biophysical Journal , 73 :52 , 1997
PubMedID: 9199771

Title : Expression and activity of mutants of fasciculin, a peptidic acetylcholinesterase inhibitor from mamba venom - Marchot_1997_J.Biol.Chem_272_3502
Author(s) : Marchot P , Prowse CN , Kanter J , Camp S , Ackermann EJ , Radic Z , Bougis PE , Taylor P
Ref : Journal of Biological Chemistry , 272 :3502 , 1997
PubMedID: 9013597

Title : Electrostatic influence on the kinetics of ligand binding to acetylcholinesterase. Distinctions between active center ligands and fasciculin - Radic_1997_J.Biol.Chem_272_23265
Author(s) : Radic Z , Kirchhoff PD , Quinn DM , McCammon JA , Taylor P
Ref : Journal of Biological Chemistry , 272 :23265 , 1997
PubMedID: 9287336

Title : Metrifonate. A viewpoint -
Author(s) : Taylor P
Ref : Drugs & Aging , 11 :497 , 1997
PubMedID: 9413708

Title : Mutant acetylcholinesterases as potential detoxification agents for organophosphate poisoning - Saxena_1997_Biochem.Pharmacol_54_269
Author(s) : Saxena A , Maxwell DM , Quinn DM , Radic Z , Taylor P , Doctor BP
Ref : Biochemical Pharmacology , 54 :269 , 1997
PubMedID: 9271331

Title : Determining ligand orientation and transphosphonylation mechanisms on acetylcholinesterase by Rp, Sp enantiomer selectivity and site-specific mutagenesis - Taylor_1997_Enantiomer_2_249
Author(s) : Taylor P , Hosea NA , Tsigelny I , Radic Z , Berman HA
Ref : Enantiomer , 2 :249 , 1997
PubMedID: 9676269

Title : Acetylcholinesterase and nicotinic acetylcholine receptor expression diverge in muscular dysgenic mice lacking the L-type calcium channel - Luo_1996_J.Neurochem_67_111
Author(s) : Luo ZD , Pincon-Raymond M , Taylor P
Ref : Journal of Neurochemistry , 67 :111 , 1996
PubMedID: 8666981

Title : Soluble monomeric acetylcholinesterase from mouse: expression, purification, and crystallization in complex with fasciculin - Marchot_1996_Prot.Sci_5_672
Author(s) : Marchot P , Ravelli RB , Raves ML , Bourne Y , Vellom DC , Kanter J , Camp S , Sussman JL , Taylor P
Ref : Protein Science , 5 :672 , 1996
PubMedID: 8845756
Gene_locus related to this paper: mouse-ACHE

Title : Regulation of acetylcholinesterase expression during neuronal differentiation - Coleman_1996_J.Biol.Chem_271_4410
Author(s) : Coleman BA , Taylor P
Ref : Journal of Biological Chemistry , 271 :4410 , 1996
PubMedID: 8626792

Title : Aspartate 74 as a primary determinant in acetylcholinesterase governing specificity to cationic organophosphonates - Hosea_1996_Biochemistry_35_10995
Author(s) : Hosea NA , Radic Z , Tsigelny I , Berman HA , Quinn DM , Taylor P
Ref : Biochemistry , 35 :10995 , 1996
PubMedID: 8718893

Title : Ligand Specificity and Gene Expression in the Cholinergic Synapse -
Author(s) : Taylor P , Radic Z , Kreienkamp HJ , Luo ZD , Pickering NA , Camp S
Ref : In Enzyme of the Cholinesterase Family - Proceedings of Fifth International Meeting on Cholinesterases , (Quinn, D.M., Balasubramanian, A.S., Doctor, B.P., Taylor, P., Eds) Plenum Publishing Corp. :15 , 1995
PubMedID:

Title : Patients with congenital myasthenia associated with end-plate acetylcholinesterase deficiency show normal sequence, mRNA splicing, and assembly of catalytic subunits - Camp_1995_J.Clin.Invest_95_333
Author(s) : Camp S , Bon S , Li Y , Getman DK , Engel AG , Massoulie J , Taylor P
Ref : Journal of Clinical Investigation , 95 :333 , 1995
PubMedID: 7814634

Title : Mutations in the Catalytic Subunit of Acetylcholinesterase do not Appear Responsible for Congenital Myasthenic Syndrome Associated with End-Plate Acetylcholinesterase Deficiency -
Author(s) : Camp S , Engel AG , Getman DK , Bon S , Massoulie J , Taylor P
Ref : In Enzyme of the Cholinesterase Family - Proceedings of Fifth International Meeting on Cholinesterases , (Quinn, D.M., Balasubramanian, A.S., Doctor, B.P., Taylor, P., Eds) Plenum Publishing Corp. :51 , 1995
PubMedID:

Title : Comparison of Acetylcholinesterase, Pyridostigmine, and HI-6 as Antidotes against Organophosphorus Compounds -
Author(s) : Maxwell DM , Brecht KM , Saxena A , Taylor P , Doctor BP
Ref : In Enzyme of the Cholinesterase Family - Proceedings of Fifth International Meeting on Cholinesterases , (Quinn, D.M., Balasubramanian, A.S., Doctor, B.P., Taylor, P., Eds) Plenum Publishing Corp. :353 , 1995
PubMedID:

Title : Regulation of Acetylcholinesterase (AChE) mRNA by Ryanodine-Sensitive and L-Type Calcium Channels during Myogenesis in Vitro and Muscle Development in Vivo -
Author(s) : Luo ZD , Pincon-Raymond M , Taylor P
Ref : In Enzyme of the Cholinesterase Family - Proceedings of Fifth International Meeting on Cholinesterases , (Quinn, D.M., Balasubramanian, A.S., Doctor, B.P., Taylor, P., Eds) Plenum Publishing Corp. :53 , 1995
PubMedID:

Title : Regulation of AChE Gene Expression in Neuronally Induced Mouse P19 Cells -
Author(s) : Coleman BA , Taylor P
Ref : In Enzyme of the Cholinesterase Family - Proceedings of Fifth International Meeting on Cholinesterases , (Quinn, D.M., Balasubramanian, A.S., Doctor, B.P., Taylor, P., Eds) Plenum Publishing Corp. :55 , 1995
PubMedID:

Title : Regulation of Human Acetylcholinesterase Gene Expression -
Author(s) : Getman DK , Inoue K , Taylor P
Ref : In Enzyme of the Cholinesterase Family - Proceedings of Fifth International Meeting on Cholinesterases , (Quinn, D.M., Balasubramanian, A.S., Doctor, B.P., Taylor, P., Eds) Plenum Publishing Corp. :56 , 1995
PubMedID:

Title : Promoter Elements of the Mouse Acetylcholinesterase Gene -
Author(s) : Mutero A , Taylor P
Ref : In Enzyme of the Cholinesterase Family - Proceedings of Fifth International Meeting on Cholinesterases , (Quinn, D.M., Balasubramanian, A.S., Doctor, B.P., Taylor, P., Eds) Plenum Publishing Corp. :57 , 1995
PubMedID:

Title : Molecular dissection of subunit interfaces in the acetylcholine receptor: identification of determinants of alpha-conotoxin M1 selectivity - Sine_1995_Neuron_15_205
Author(s) : Sine SM , Kreienkamp HJ , Bren N , Maeda RK , Taylor P
Ref : Neuron , 15 :205 , 1995
PubMedID: 7619523

Title : Specificity and orientation of trigonal carboxyl esters and tetrahedral alkylphosphonyl esters in cholinesterases - Hosea_1995_Biochemistry_34_11528
Author(s) : Hosea NA , Berman HA , Taylor P
Ref : Biochemistry , 34 :11528 , 1995
PubMedID: 7547883

Title : Amino acid residues controlling reactivation of organophosphonyl conjugates of acetylcholinesterase by mono- and bisquaternary oximes - Ashani_1995_J.Biol.Chem_270_6370
Author(s) : Ashani Y , Radic Z , Tsigelny I , Vellom DC , Pickering NA , Quinn DM , Doctor BP , Taylor P
Ref : Journal of Biological Chemistry , 270 :6370 , 1995
PubMedID: 7890775

Title : Amino Acid Residues in Acetylcholinesterase which Influence Fasciculin Inhibition -
Author(s) : Radic Z , Quinn DM , Vellom DC , Camp S , Taylor P
Ref : In Enzyme of the Cholinesterase Family - Proceedings of Fifth International Meeting on Cholinesterases , (Quinn, D.M., Balasubramanian, A.S., Doctor, B.P., Taylor, P., Eds) Plenum Publishing Corp. :183 , 1995
PubMedID:

Title : Structural Determinants of Fasciculin Specificity for Acetylcholinesterase -
Author(s) : Marchot P , Camp S , Radic Z , Bougis PE , Taylor P
Ref : In Enzyme of the Cholinesterase Family - Proceedings of Fifth International Meeting on Cholinesterases , (Quinn, D.M., Balasubramanian, A.S., Doctor, B.P., Taylor, P., Eds) Plenum Publishing Corp. :197 , 1995
PubMedID:

Title : Amino Acid Residues that Control Mono- and Bisquaternary Oxime-Induced Reactivation of O-Ethyl Methylphosphonylated Cholinesterases -
Author(s) : Ashani Y , Radic Z , Tsigelny I , Vellom DC , Pickering NA , Quinn DM , Doctor BP , Taylor P
Ref : In Enzyme of the Cholinesterase Family - Proceedings of Fifth International Meeting on Cholinesterases , (Quinn, D.M., Balasubramanian, A.S., Doctor, B.P., Taylor, P., Eds) Plenum Publishing Corp. :133 , 1995
PubMedID:

Title : Allosteric control of acetylcholinesterase catalysis by fasciculin - Radic_1995_J.Biol.Chem_270_20391
Author(s) : Radic Z , Quinn DM , Vellom DC , Camp S , Taylor P
Ref : Journal of Biological Chemistry , 270 :20391 , 1995
PubMedID: 7657613

Title : London Dispersion Interactions in Molecular Recognition by Acetylcholinesterase -
Author(s) : Quinn DM , Nair HK , Seravalli J , Lee K , Arbuckle T , Radic Z , Vellom DC , Pickering NA , Taylor P
Ref : In Enzyme of the Cholinesterase Family - Proceedings of Fifth International Meeting on Cholinesterases , (Quinn, D.M., Balasubramanian, A.S., Doctor, B.P., Taylor, P., Eds) Plenum Publishing Corp. :228 , 1995
PubMedID:

Title : The Function of Electrostatics in Acetylcholinesterase Catalysis -
Author(s) : Quinn DM , Seravalli J , Nair HK , Medhekar R , Husseini B , Radic Z , Vellom DC , Pickering NA , Taylor P
Ref : In Enzyme of the Cholinesterase Family - Proceedings of Fifth International Meeting on Cholinesterases , (Quinn, D.M., Balasubramanian, A.S., Doctor, B.P., Taylor, P., Eds) Plenum Publishing Corp. :203 , 1995
PubMedID:

Title : Theoretical analysis of the structure of the peptide fasciculin and its docking to acetylcholinesterase - van den Born_1995_Prot.Sci_4_703
Author(s) : van den Born HK , Radic Z , Marchot P , Taylor P , Tsigelny I
Ref : Protein Science , 4 :703 , 1995
PubMedID: 7613468

Title : Intersubunit contacts governing assembly of the mammalian nicotinic acetylcholine receptor - Kreienkamp_1995_Neuron_14_635
Author(s) : Kreienkamp HJ , Maeda RK , Sine SM , Taylor P
Ref : Neuron , 14 :635 , 1995
PubMedID: 7695910

Title : Structural bases for the specificity of cholinesterase catalysis and inhibition. - Taylor_1995_Toxicol.Lett_83_453
Author(s) : Taylor P , Radic Z , Hosea NA , Camp S , Marchot P , Berman HA
Ref : Toxicology Letters , 83 :453 , 1995
PubMedID: 8597093

Title : Acetylcholinesterase inhibition by fasciculin: crystal structure of the complex - Bourne_1995_Cell_83_503
Author(s) : Bourne Y , Taylor P , Marchot P
Ref : Cell , 83 :503 , 1995
PubMedID: 8521480
Gene_locus related to this paper: mouse-ACHE

Title : Organophosphate Specificity of Acyl Pocket Cholinesterase Mutants -
Author(s) : Pickering NA , Taylor P , Berman HA
Ref : In Enzyme of the Cholinesterase Family - Proceedings of Fifth International Meeting on Cholinesterases , (Quinn, D.M., Balasubramanian, A.S., Doctor, B.P., Taylor, P., Eds) Plenum Publishing Corp. :227 , 1995
PubMedID:

Title : Promoter elements of the mouse acetylcholinesterase gene. Transcriptional regulation during muscle differentiation - Mutero_1995_J.Biol.Chem_270_1866
Author(s) : Mutero A , Camp S , Taylor P
Ref : Journal of Biological Chemistry , 270 :1866 , 1995
PubMedID: 7829523

Title : Transcription factor repression and activation of the human acetylcholinesterase gene - Getman_1995_J.Biol.Chem_270_23511
Author(s) : Getman DK , Mutero A , Inoue K , Taylor P
Ref : Journal of Biological Chemistry , 270 :23511 , 1995
PubMedID: 7559515

Title : Site of fasciculin interaction with acetylcholinesterase - Radic_1994_J.Biol.Chem_269_11233
Author(s) : Radic Z , Duran R , Vellom DC , Li Y , Cervenansky C , Taylor P
Ref : Journal of Biological Chemistry , 269 :11233 , 1994
PubMedID: 8157652

Title : Conserved tyrosines in the alpha subunit of the nicotinic acetylcholine receptor stabilize quaternary ammonium groups of agonists and curariform antagonists - Sine_1994_J.Biol.Chem_269_8808
Author(s) : Sine SM , Quiram P , Papanikolaou F , Kreienkamp HJ , Taylor P
Ref : Journal of Biological Chemistry , 269 :8808 , 1994
PubMedID: 8132615

Title : Expression and ligand specificity of acetylcholinesterase and the nicotinic receptor: a tale of two cholinergic sites - Taylor_1994_Biochem.Soc.Trans_22_740
Author(s) : Taylor P , Radic Z , Kreienkamp HJ , Maeda RK , Luo ZD , Fuentes ME , Vellom DC , Pickering NA
Ref : Biochemical Society Transactions , 22 :740 , 1994
PubMedID: 7821676

Title : Identification of amino acid residues involved in the binding of Huperzine A to cholinesterases - Saxena_1994_Protein.Sci_3_1770
Author(s) : Saxena A , Qian N , Kovach IM , Kozikowski AP , Pang YP , Vellom DC , Radic Z , Quinn DM , Taylor P , Doctor BP
Ref : Protein Science , 3 :1770 , 1994
PubMedID: 7849595

Title : Glycosylation sites selectively interfere with alpha-toxin binding to the nicotinic acetylcholine receptor - Kreienkamp_1994_J.Biol.Chem_269_8108
Author(s) : Kreienkamp HJ , Sine SM , Maeda RK , Taylor P
Ref : Journal of Biological Chemistry , 269 :8108 , 1994
PubMedID: 7907588

Title : The cholinesterases: from genes to proteins - Taylor_1994_Annu.Rev.Pharmacol.Toxicol_34_281
Author(s) : Taylor P , Radic Z
Ref : Annual Review of Pharmacology & Toxicology , 34 :281 , 1994
PubMedID: 8042853

Title : The spectrum of congenital end-plate acetylcholinesterase deficiency -
Author(s) : Hutchinson DO , Engel AG , Walls TJ , Nakano S , Camp S , Taylor P , Harper CM , Brengman JM
Ref : Annals of the New York Academy of Sciences , 681 :469 , 1993
PubMedID: 8395162

Title : Tissue-specific expression and alternative mRNA processing of the mammalian acetylcholinesterase gene - Li_1993_J.Biol.Chem_268_5790
Author(s) : Li Y , Camp S , Taylor P
Ref : Journal of Biological Chemistry , 268 :5790 , 1993
PubMedID: 8449945

Title : Epitope mapping of form-specific and nonspecific antibodies to acetylcholinesterase - Wasserman_1993_J.Neurochem_61_2124
Author(s) : Wasserman L , Doctor BP , Gentry MK , Taylor P
Ref : Journal of Neurochemistry , 61 :2124 , 1993
PubMedID: 7504082

Title : Amino acid residues controlling acetylcholinesterase and butyrylcholinesterase specificity - Vellom_1993_Biochemistry_32_12
Author(s) : Vellom DC , Radic Z , Li Y , Pickering NA , Camp S , Taylor P
Ref : Biochemistry , 32 :12 , 1993
PubMedID: 8418833

Title : Congenital endplate acetylcholinesterase deficiency - Hutchinson_1993_Brain_116_633
Author(s) : Hutchinson DO , Walls TJ , Nakano S , Camp S , Taylor P , Harper CM , Groover RV , Peterson HA , Jamieson DG , Engel AG
Ref : Brain , 116 :633 , 1993
PubMedID: 8390325

Title : Three distinct domains in the cholinesterase molecule confer selectivity for acetyl- and butyrylcholinesterase inhibitors - Radic_1993_Biochemistry_32_12074
Author(s) : Radic Z , Pickering NA , Vellom DC , Camp S , Taylor P
Ref : Biochemistry , 32 :12074 , 1993
PubMedID: 8218285

Title : Structure and regulation of expression of the acetylcholinesterase gene - Taylor_1993_Chem.Biol.Interact_87_199
Author(s) : Taylor P , Li Y , Camp S , Rachinsky TL , Ekstrom TJ , Getman DK , Fuentes ME , Vellom DC , Radic Z
Ref : Chemico-Biological Interactions , 87 :199 , 1993
PubMedID: 8343976

Title : The role of glutamate-199 in the aging of cholinesterase - Saxena_1993_Biochem.Biophys.Res.Commun_197_343
Author(s) : Saxena A , Doctor BP , Maxwell DM , Lenz DE , Radic Z , Taylor P
Ref : Biochemical & Biophysical Research Communications , 197 :343 , 1993
PubMedID: 7902714

Title : Promoter elements and transcriptional regulation of the acetylcholinesterase gene - Ekstrom_1993_DNA.Cell.Biol_12_63
Author(s) : Ekstrom TJ , Klump WM , Getman DK , Karin M , Taylor P
Ref : DNA & Cell Biology , 12 :63 , 1993
PubMedID: 8422273

Title : Promoter elements and transcriptional control of the mouse acetylcholinesterase gene - Li_1993_J.Biol.Chem_268_3563
Author(s) : Li Y , Camp S , Rachinsky TL , Bongiorno C , Taylor P
Ref : Journal of Biological Chemistry , 268 :3563 , 1993
PubMedID: 8429032

Title : Control of acetylcholinesterase gene expression during myogenesis - Fuentes_1993_Neuron_10_679
Author(s) : Fuentes ME , Taylor P
Ref : Neuron , 10 :679 , 1993
PubMedID: 8386528

Title : The human gene encoding acetylcholinesterase is located on the long arm of chromosome 7 - Getman_1992_Am.J.Hum.Genet_51_170
Author(s) : Getman DK , Eubanks JH , Camp S , Evans GA , Taylor P
Ref : American Journal of Human Genetics , 51 :170 , 1992
PubMedID: 1609795

Title : Expression of recombinant acetylcholinesterase in a baculovirus system: kinetic properties of glutamate 199 mutants - Radic_1992_Biochemistry_31_9760
Author(s) : Radic Z , Gibney G , Kawamoto S , MacPhee-Quigley K , Bongiorno C , Taylor P
Ref : Biochemistry , 31 :9760 , 1992
PubMedID: 1356436

Title : Impact of Recombinant DNA Technology and Protein Structure Determination on Past and Future Studies on Acetylcholinesterase -
Author(s) : Taylor P
Ref : In Multidisciplinary approaches to cholinesterase functions - Proceedings of Fourth International Meeting on Cholinesterases , (Shafferman, A. and Velan, B., Eds) Plenum Press, New York :1 , 1992
PubMedID:

Title : Assignment of the gene for acetylcholinesterase to distal mouse chromosome 5 - Rachinsky_1992_Genomics_14_511
Author(s) : Rachinsky TL , Crenshaw EBd , Taylor P
Ref : Genomics , 14 :511 , 1992
PubMedID: 1358806

Title : Poster: Characterization of peripheral anionic site peptides of AChE by photoaffinity labeling with monoazidopropidium (MAP) -
Author(s) : Amitai G , Taylor P
Ref : In: Cholinesterases: Structure, Function, Mechanism, Genetics, and Cell Biology , (Massoulie J, Barnard EA, Chatonnet A, Bacou F, Doctor BP, Quinn DM) American Chemical Society, Washington, DC :285 , 1991
PubMedID:

Title : Role of the peripheral anionic site on acetylcholinesterase: inhibition by substrates and coumarin derivatives - Radic_1991_Mol.Pharmacol_39_98
Author(s) : Radic Z , Reiner E , Taylor P
Ref : Molecular Pharmacology , 39 :98 , 1991
PubMedID: 1987454

Title : A comparative Raman spectroscopic study of cholinesterases - Aslanian_1991_Biochimie_73_1375
Author(s) : Aslanian D , Grof P , Bon S , Masson P , Negrerie M , Chatel JM , Balkanski M , Taylor P , Massoulie J
Ref : Biochimie , 73 :1375 , 1991
PubMedID: 1799630

Title : Features of Acetylcholinesterase Structure and Gene Expression Emerging from Recent Recombinant DNA Studies -
Author(s) : Taylor P , Gibney G , Camp S , Maulet Y , Ekstrom TJ , Rachinsky TL , Li Y
Ref : In: Cholinesterases: Structure, Function, Mechanism, Genetics, and Cell Biology , (Massoulie J, Barnard EA, Chatonnet A, Bacou F, Doctor BP, Quinn DM) American Chemical Society, Washington, DC :179 , 1991
PubMedID:

Title : Mechanism of Substrate Inhibition of Acetylcholinesterase -
Author(s) : Reiner E , Aldridge WN , Simeon-Rudolf V , Radic Z , Taylor P
Ref : In: Cholinesterases: Structure, Function, Mechanism, Genetics, and Cell Biology , (Massoulie J, Barnard EA, Chatonnet A, Bacou F, Doctor BP, Quinn DM) American Chemical Society, Washington, DC :227 , 1991
PubMedID:

Title : Poster: Use of the polymerase chain reaction for homology probing of butyrylchoIinesterase (BCHE) in several animal species -
Author(s) : Arpagaus M , Vaughan TA , La Du BN , Lockridge O , Masson P , Chatonnet A , Newton M , Taylor P
Ref : In: Cholinesterases: Structure, Function, Mechanism, Genetics, and Cell Biology , (Massoulie J, Barnard EA, Chatonnet A, Bacou F, Doctor BP, Quinn DM) American Chemical Society, Washington, DC :194 , 1991
PubMedID:

Title : The cholinesterases. -
Author(s) : Taylor P
Ref : Journal of Biological Chemistry , 266 :4025 , 1991
PubMedID: 1999397

Title : Gene structure of mammalian acetylcholinesterase. Alternative exons dictate tissue-specific expression - Li_1991_J.Biol.Chem_266_23083
Author(s) : Li Y , Camp S , Rachinsky TL , Getman DK , Taylor P
Ref : Journal of Biological Chemistry , 266 :23083 , 1991
PubMedID: 1744105

Title : Poster: A comparative raman spectroscopic study of cholinesterases -
Author(s) : Aslanian D , Grof P , Masson P , Taylor P , Bon S , Chatel JM , Massoulie J
Ref : In: Cholinesterases: Structure, Function, Mechanism, Genetics, and Cell Biology , (Massoulie J, Barnard EA, Chatonnet A, Bacou F, Doctor BP, Quinn DM) American Chemical Society, Washington, DC :56 , 1991
PubMedID:

Title : Poster: Onchidal: a naturally occurring irreversible inhibitor of acetylcholinesterase with a novel mechanism of action -
Author(s) : Abramson SN , Radic Z , Manker D , Faulkner DJ , Taylor P
Ref : In: Cholinesterases: Structure, Function, Mechanism, Genetics, and Cell Biology , (Massoulie J, Barnard EA, Chatonnet A, Bacou F, Doctor BP, Quinn DM) American Chemical Society, Washington, DC :296 , 1991
PubMedID:

Title : Poster: Interaction of reversible and irreversible inhibitors with a peripheral site on acetylcholinesterase -
Author(s) : Friboulet A , Taylor P , Rieger F
Ref : In: Cholinesterases: Structure, Function, Mechanism, Genetics, and Cell Biology , (Massoulie J, Barnard EA, Chatonnet A, Bacou F, Doctor BP, Quinn DM) American Chemical Society, Washington, DC :286 , 1991
PubMedID:

Title : Biosynthesis of Torpedo acetylcholinesterase in mammalian cells. Functional expression and mutagenesis of the glycophospholipid-anchored form [published erratum appears in J Biol Chem 1990 Nov 15\;265(32):20051] - Gibney_1990_J.Biol.Chem_265_12576
Author(s) : Gibney G , Taylor P
Ref : Journal of Biological Chemistry , 265 :12576 , 1990
PubMedID: 2165068

Title : Single gene encodes glycophospholipid-anchored and asymmetric acetylcholinesterase forms: alternative coding exons contain inverted repeat sequences - Maulet_1990_Neuron_4_289
Author(s) : Maulet Y , Camp S , Gibney G , Rachinsky TL , Ekstrom TJ , Taylor P
Ref : Neuron , 4 :289 , 1990
PubMedID: 2306366

Title : Studies on the topography of the catalytic site of acetylcholinesterase using polyclonal and monoclonal antibodies - Ogert_1990_J.Neurochem_55_756
Author(s) : Ogert RA , Gentry MK , Richardson EC , Deal CD , Abramson SN , Alving CR , Taylor P , Doctor BP
Ref : Journal of Neurochemistry , 55 :756 , 1990
PubMedID: 1696619

Title : Mutagenesis of essential functional residues in acetylcholinesterase - Gibney_1990_Proc.Natl.Acad.Sci.U.S.A_87_7546
Author(s) : Gibney G , Camp S , Dionne M , MacPhee-Quigley K , Taylor P
Ref : Proceedings of the National Academy of Sciences of the United States of America , 87 :7546 , 1990
PubMedID: 2217185

Title : Molecular cloning of mouse acetylcholinesterase: tissue distribution of alternatively spliced mRNA species - Rachinsky_1990_Neuron_5_317
Author(s) : Rachinsky TL , Camp S , Li Y , Ekstrom TJ , Newton M , Taylor P
Ref : Neuron , 5 :317 , 1990
PubMedID: 2400605
Gene_locus related to this paper: mouse-ACHE , mouse-BCHE

Title : Interaction of an organophosphate with a peripheral site on acetylcholinesterase - Friboulet_1990_Biochemistry_29_914
Author(s) : Friboulet A , Rieger F , Goudou D , Amitai G , Taylor P
Ref : Biochemistry , 29 :914 , 1990
PubMedID: 2340283

Title : Differences in structure and distribution of the molecular forms of acetylcholinesterase - Abramson_1989_J.Cell.Biol_108_2301
Author(s) : Abramson SN , Ellisman MH , Deerinck TJ , Maulet Y , Gentry MK , Doctor BP , Taylor P
Ref : Journal of Cell Biology , 108 :2301 , 1989
PubMedID: 2472404

Title : Definition, at the molecular level, of a thyroglobulin- acetylcholinesterase shared epitope: study of its pathophysiological significance in patients with Graves' ophthalmopathy - Ludgate_1989_Autoimmunity_3_167
Author(s) : Ludgate M , Dong Q , Dreyfus PA , Zakut H , Taylor P , Vassart G , Soreq H
Ref : Autoimmunity , 3 :167 , 1989
PubMedID: 2485081

Title : Onchidal: a naturally occurring irreversible inhibitor of acetylcholinesterase with a novel mechanism of action - Abramson_1989_Mol.Pharmacol_36_349
Author(s) : Abramson SN , Radic Z , Manker D , Faulkner DJ , Taylor P
Ref : Molecular Pharmacology , 36 :349 , 1989
PubMedID: 2779521

Title : Multiple messenger RNA species give rise to the structural diversity in acetylcholinesterase - Schumacher_1988_J.Biol.Chem_263_18979
Author(s) : Schumacher M , Maulet Y , Camp S , Taylor P
Ref : Journal of Biological Chemistry , 263 :18979 , 1988
PubMedID: 3198606

Title : Divergence in primary structure between the molecular forms of acetylcholinesterase - Gibney_1988_J.Biol.Chem_263_1140
Author(s) : Gibney G , MacPhee-Quigley K , Thompson B , Vedvick TS , Low MG , Taylor SS , Taylor P
Ref : Journal of Biological Chemistry , 263 :1140 , 1988
PubMedID: 3335534

Title : Raman spectroscopic study on the conformation of 11 S form acetylcholinesterase from Torpedo californica - Aslanian_1987_FEBS.Lett_219_202
Author(s) : Aslanian D , Grof P , Negrerie M , Balkanski M , Taylor P
Ref : FEBS Letters , 219 :202 , 1987
PubMedID: 3595873

Title : Decidium. A novel fluorescent probe of the agonist\/antagonist and noncompetitive inhibitor sites on the nicotinic acetylcholine receptor - Johnson_1987_J.Biol.Chem_262_14022
Author(s) : Johnson DA , Brown RD , Herz JM , Berman HA , Andreasen GL , Taylor P
Ref : Journal of Biological Chemistry , 262 :14022 , 1987
PubMedID: 3654651

Title : Evidence for the interaction of acetylcholinesterase inhibitors with catalytic and extra-catalytic sites on the insolubilized enzyme -
Author(s) : Friboulet A , Goudou D , Taylor P , Rieger F
Ref : Progress in Clinical & Biological Research , 253 :277 , 1987
PubMedID: 3432291

Title : Site selectivity of fluorescent bisquaternary phenanthridinium ligands for acetylcholinesterase - Berman_1987_Mol.Pharmacol_31_610
Author(s) : Berman HA , Decker MM , Nowak MW , Leonard KJ , McCauley M , Baker WM , Taylor P
Ref : Molecular Pharmacology , 31 :610 , 1987
PubMedID: 3600605

Title : Primary structure of acetylcholinesterase: implications for regulation and function. - Schumacher_1986_Fed.Proc_45_2976
Author(s) : Schumacher M , Camp S , Maulet Y , Newton M , MacPhee-Quigley K , Taylor SS , Friedmann T , Taylor P
Ref : Federation Proceedings , 45 :2976 , 1986
PubMedID: 3536598

Title : Target sites for anticholinesterases on the ventral surface of the medulla oblongata: hypotension elicited by organophosphorus agents - Edery_1986_J.Autonomic.Pharmacol_6_195
Author(s) : Edery H , Geyer MA , Taylor P , Berman HA
Ref : Journal of Autonomic Pharmacology , 6 :195 , 1986
PubMedID: 3771592

Title : Primary structure of Torpedo californica acetylcholinesterase deduced from its cDNA sequence - Schumacher_1986_Nature_319_407
Author(s) : Schumacher M , Camp S , Maulet Y , Newton M , MacPhee-Quigley K , Taylor SS , Friedmann T , Taylor P
Ref : Nature , 319 :407 , 1986
PubMedID: 3753747
Gene_locus related to this paper: torca-ACHE

Title : Profile of the disulfide bonds in acetylcholinesterase - MacPhee-Quigley_1986_J.Biol.Chem_261_13565
Author(s) : MacPhee-Quigley K , Vedvick TS , Taylor P , Taylor SS
Ref : Journal of Biological Chemistry , 261 :13565 , 1986
PubMedID: 3759980

Title : Circular dichroism studies of acetylcholinesterase conformation. Comparison of the 11 S and 5.6 S species and the differences induced by inhibitory ligands - Manavalan_1985_Biochim.Biophys.Acta_829_365
Author(s) : Manavalan P , Taylor P , Johnson WC, Jr.
Ref : Biochimica & Biophysica Acta , 829 :365 , 1985
PubMedID: 4005268

Title : Primary structures of the catalytic subunits from two molecular forms of acetylcholinesterase. A comparison of NH2-terminal and active center sequences - MacPhee-Quigley_1985_J.Biol.Chem_260_12185
Author(s) : MacPhee-Quigley K , Taylor P , Taylor SS
Ref : Journal of Biological Chemistry , 260 :12185 , 1985
PubMedID: 3900071

Title : Flexibility of the molecular forms of acetylcholinesterase measured with steady-state and time-correlated fluorescence polarization spectroscopy - Berman_1985_Biochemistry_24_7140
Author(s) : Berman HA , Yguerabide J , Taylor P
Ref : Biochemistry , 24 :7140 , 1985
PubMedID: 4084569

Title : The relationship between alpha 1-adrenergic receptor occupation and the mobilization of intracellular calcium - Amitai_1984_J.Biol.Chem_259_12519
Author(s) : Amitai G , Brown RD , Taylor P
Ref : Journal of Biological Chemistry , 259 :12519 , 1984
PubMedID: 6092338

Title : Molecular aspects of the biosynthesis and disposition of multiple forms of acetylcholinesterase -
Author(s) : Taylor P , Camp S , Lee SL , Amitai G , Taylor SS , Doctor BP
Ref : In: Cholinesterases, fundamental and applied aspects : proceedings of the Second International Meeting on Cholinesterases , (Brzin M, Barnard EA, Sket D, Eds) De Gruyter :145 , 1984
PubMedID:

Title : Poster 8. Antigenic and structural differences in the catalytic subunits of the molecular forms of acetylcholinesterase -
Author(s) : Doctor BP , Taylor P
Ref : In: Cholinesterases, fundamental and applied aspects : proceedings of the Second International Meeting on Cholinesterases , (Brzin M, Barnard EA, Sket D, Eds) De Gruyter , 1984
PubMedID:

Title : Interaction of a fluorescent acyldicholine with the nicotinic acetylcholine receptor and acetylcholinesterase - Bolger_1984_Mol.Pharmacol_26_57
Author(s) : Bolger MB , Dionne V , Chrivia J , Johnson DA , Taylor P
Ref : Molecular Pharmacology , 26 :57 , 1984
PubMedID: 6547767

Title : Antigenic and structural differences in the catalytic subunits of the molecular forms of acetylcholinesterase - Doctor_1983_Proc.Natl.Acad.Sci.U.S.A_80_5767
Author(s) : Doctor BP , Camp S , Gentry MK , Taylor SS , Taylor P
Ref : Proceedings of the National Academy of Sciences of the United States of America , 80 :5767 , 1983
PubMedID: 6193524

Title : Structural characterization of the asymmetric (17 + 13) S forms of acetylcholinesterase from Torpedo. I. Analysis of subunit composition -
Author(s) : Lee SL , Heinemann SF , Taylor P
Ref : Journal of Biological Chemistry , 257 :12282 , 1982
PubMedID: 7118944

Title : Structural characterization of the asymmetric (17 + 13) S species of acetylcholinesterase from Torpedo. II. Component peptides obtained by selective proteolysis and disulfide bond reduction -
Author(s) : Lee SL , Taylor P
Ref : Journal of Biological Chemistry , 257 :12292 , 1982
PubMedID: 6288713

Title : Characterization of a hydrophobic, dimeric form of acetylcholinesterase from Torpedo -
Author(s) : Lee SL , Camp S , Taylor P
Ref : Journal of Biological Chemistry , 257 :12302 , 1982
PubMedID: 6288714

Title : Local anesthetics and histrionicotoxin are allosteric inhibitors of the acetylcholine receptor. Studies of clonal muscle cells -
Author(s) : Sine SM , Taylor P
Ref : Journal of Biological Chemistry , 257 :8106 , 1982
PubMedID: 7085658

Title : Relationship between reversible antagonist occupancy and the functional capacity of the acetylcholine receptor -
Author(s) : Sine SM , Taylor P
Ref : Journal of Biological Chemistry , 256 :6692 , 1981
PubMedID: 7240238

Title : Spectroscopic studies on acetylcholinesterase: influence of peripheral- site occupation on active-center conformation -
Author(s) : Berman HA , Becktel W , Taylor P
Ref : Biochemistry , 20 :4803 , 1981
PubMedID: 7295650

Title : Development of the multiple molecular forms of acetylcholinesterase in chick paravertebral sympathetic ganglia: an in vivo and in vitro study - Taylor_1980_Brain.Res_182_383
Author(s) : Taylor P , Rieger F , Greene LA
Ref : Brain Research , 182 :383 , 1980
PubMedID: 7357392

Title : The relationship between agonist occupation and the permeability response of the cholinergic receptor revealed by bound cobra alpha-toxin - Sine_1980_J.Biol.Chem_255_10144
Author(s) : Sine SM , Taylor P
Ref : Journal of Biological Chemistry , 255 :10144 , 1980
PubMedID: 7430118

Title : Fluorescence energy transfer on acetylcholinesterase: spatial relationship between peripheral site and active center -
Author(s) : Berman HA , Yguerabide J , Taylor P
Ref : Biochemistry , 19 :2226 , 1980
PubMedID: 7378357

Title : Kinetics of association between bisquaternary ammonium ligands and acetylcholinesterase. Evidence for two conformational states of the enzyme from stopped-flow measurements of fluorescence -
Author(s) : Bolger MB , Taylor P
Ref : Biochemistry , 18 :3622 , 1979
PubMedID: 476071

Title : Ligand-induced conformational changes in acetylcholinesterase investigated with fluorescent phosphonates -
Author(s) : Epstein DJ , Berman HA , Taylor P
Ref : Biochemistry , 18 :4749 , 1979
PubMedID: 497167

Title : Fluorescent phosphonate label for serine hydrolases, pyrenebutyl methylphosphonofluoridate: reaction with acetylcholinesterase -
Author(s) : Berman HA , Taylor P
Ref : Biochemistry , 17 :1704 , 1978
PubMedID: 566114

Title : Structure of Acetylcholinesterase: Its Relationship to the Postsynaptic Membrane -
Author(s) : Taylor P , Lwebuga-Mukasa JS , Lappi S , Berman HA
Ref : Advances in Behavioral Biology , 24 :239 , 1978
PubMedID:

Title : Molecular forms of acetylcholinesterase from Torpedo californica: their relationship to synaptic membranes - Lwebuga-Mukasa_1976_Biochemistry_15_1425
Author(s) : Lwebuga-Mukasa JS , Lappi S , Taylor P
Ref : Biochemistry , 15 :1425 , 1976
PubMedID: 177042

Title : Affinity partitioning of membranes. Cholinergic receptor-containing membranes from Torpedo californica - Flanagan_1976_J.Biol.Chem_251_858
Author(s) : Flanagan SD , Barondes SH , Taylor P
Ref : Journal of Biological Chemistry , 251 :858 , 1976
PubMedID: 1249060

Title : Spectroscopic studies of ligand interactions with acetylcholinesterase -
Author(s) : Taylor P , Lwebuga-Mukasa JS , Berman HA , Lappi S
Ref : Croatica Chemica Acta , 47 :251 , 1975
PubMedID:

Title : Affinity partitioning of acetylcholine receptor enriched membranes and their purification -
Author(s) : Flanagan SD , Taylor P , Barondes SH
Ref : Nature , 254 :441 , 1975
PubMedID: 1118030

Title : Interaction of fluorescence probes with acetylcholinesterase. The site and specificity of propidium binding - Taylor_1975_Biochemistry_14_1989
Author(s) : Taylor P , Lappi S
Ref : Biochemistry , 14 :1989 , 1975
PubMedID: 1125207

Title : Purification of acetylcholine receptor enriched membranes by use of affinity partitioning -
Author(s) : Flanagan SD , Taylor P , Barondes SH
Ref : Croatica Chemica Acta , 47 :449 , 1975
PubMedID:

Title : General discussion on models for the ligand binding sites of cholinesterase -
Author(s) : Reiner E , Aldridge WN , Hopff WH , Taylor P , Krupka RM , Rosenberry TL , Augustinsson KB , Mooser G , O'Brien RD , Brodbeck U , Massoulie J , Maricic S , Eldefrawi ME , Silman I
Ref : Croatica Chemica Acta , 47 :499 , 1975
PubMedID:

Title : Acetylcholinesterase from Torpedo: characterization of an enzyme species isolated by lytic procedures -
Author(s) : Taylor P , Jones JW , Jacobs NM
Ref : Molecular Pharmacology , 10 :78 , 1974
PubMedID: 4846184

Title : Interaction between bisquaternary ammonium ligands and acetylcholinesterase: complex formation studied by fluorescence quenching -
Author(s) : Taylor P , Jacobs NM
Ref : Molecular Pharmacology , 10 :93 , 1974
PubMedID: 4846185