Holst JJ

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References (36)

Title : Pharmacokinetics of exogenous GIP(1-42) in C57Bl\/6 mice\; Extremely rapid degradation but marked variation between available assays - Boer_2020_Peptides_136_170457
Author(s) : Boer GA , Hartmann B , Holst JJ
Ref : Peptides , 136 :170457 , 2020
Abstract : Boer_2020_Peptides_136_170457
ESTHER : Boer_2020_Peptides_136_170457
PubMedSearch : Boer_2020_Peptides_136_170457
PubMedID: 33245951

Title : In vivo positron emission tomography imaging of decreased parasympathetic innervation in the gut of vagotomized patients - Fedorova_2019_Neurogastroenterol.Motil__e13759
Author(s) : Fedorova TD , Knudsen K , Hartmann B , Holst JJ , Viborg Mortensen F , Krogh K , Borghammer P
Ref : Neurogastroenterol Motil , :e13759 , 2019
Abstract : Fedorova_2019_Neurogastroenterol.Motil__e13759
ESTHER : Fedorova_2019_Neurogastroenterol.Motil__e13759
PubMedSearch : Fedorova_2019_Neurogastroenterol.Motil__e13759
PubMedID: 31715652

Title : Why is it so difficult to measure glucagon-like peptide-1 in a mouse? - Windelov_2017_Diabetologia_60_2066
Author(s) : Windelov JA , Wewer Albrechtsen NJ , Kuhre RE , Jepsen SL , Hornburg D , Pedersen J , Jensen EP , Galsgaard KD , Winther-Sorensen M , Orgaard A , Deacon CF , Mann M , Kissow H , Hartmann B , Holst JJ
Ref : Diabetologia , 60 :2066 , 2017
Abstract : Windelov_2017_Diabetologia_60_2066
ESTHER : Windelov_2017_Diabetologia_60_2066
PubMedSearch : Windelov_2017_Diabetologia_60_2066
PubMedID: 28669086

Title : Inhibition of DPP-4 with Vildagliptin Improved Insulin Secretion in Response to Oral as well as Isoglycemic Intravenous Glucose without Numerically Changing the Incretin Effect in Patients with Type 2 Diabetes - Vardarli_2011_J.Clin.Endocrinol.Metab_96_945
Author(s) : Vardarli I , Nauck MA , Kothe LD , Deacon CF , Holst JJ , Schweizer A , Foley JE
Ref : J Clinical Endocrinology Metab , 96 :945 , 2011
Abstract : Vardarli_2011_J.Clin.Endocrinol.Metab_96_945
ESTHER : Vardarli_2011_J.Clin.Endocrinol.Metab_96_945
PubMedSearch : Vardarli_2011_J.Clin.Endocrinol.Metab_96_945
PubMedID: 21239518

Title : Secretion of glucagon-like peptide-1 (GLP-1) in type 2 diabetes: what is up, what is down? - Nauck_2011_Diabetologia_54_10
Author(s) : Nauck MA , Vardarli I , Deacon CF , Holst JJ , Meier JJ
Ref : Diabetologia , 54 :10 , 2011
Abstract : Nauck_2011_Diabetologia_54_10
ESTHER : Nauck_2011_Diabetologia_54_10
PubMedSearch : Nauck_2011_Diabetologia_54_10
PubMedID: 20871975

Title : Administration of a dipeptidyl peptidase IV inhibitor enhances the intestinal adaptation in a mouse model of short bowel syndrome - Okawada_2011_Surgery_150_217
Author(s) : Okawada M , Holst JJ , Teitelbaum DH
Ref : Surgery , 150 :217 , 2011
Abstract : Okawada_2011_Surgery_150_217
ESTHER : Okawada_2011_Surgery_150_217
PubMedSearch : Okawada_2011_Surgery_150_217
PubMedID: 21719060

Title : Secretion and dipeptidyl peptidase-4-mediated metabolism of incretin hormones after a mixed meal or glucose ingestion in obese compared to lean, nondiabetic men - Carr_2010_J.Clin.Endocrinol.Metab_95_872
Author(s) : Carr RD , Larsen MO , Jelic K , Lindgren O , Vikman J , Holst JJ , Deacon CF , Ahren B
Ref : J Clinical Endocrinology Metab , 95 :872 , 2010
Abstract : Carr_2010_J.Clin.Endocrinol.Metab_95_872
ESTHER : Carr_2010_J.Clin.Endocrinol.Metab_95_872
PubMedSearch : Carr_2010_J.Clin.Endocrinol.Metab_95_872
PubMedID: 20008019

Title : The effect of DPP-4 inhibition with sitagliptin on incretin secretion and on fasting and postprandial glucose turnover in subjects with impaired fasting glucose - Bock_2010_Clin.Endocrinol.(Oxf)_73_189
Author(s) : Bock G , Dalla Man C , Micheletto F , Basu R , Giesler PD , Laugen J , Deacon CF , Holst JJ , Toffolo G , Cobelli C , Rizza RA , Vella A
Ref : Clinical Endocrinology (Oxf) , 73 :189 , 2010
Abstract : Bock_2010_Clin.Endocrinol.(Oxf)_73_189
ESTHER : Bock_2010_Clin.Endocrinol.(Oxf)_73_189
PubMedSearch : Bock_2010_Clin.Endocrinol.(Oxf)_73_189
PubMedID: 20039889

Title : Glucagon and glucagon-like peptides 1 and 2 - Holst_2010_Results.Probl.Cell.Differ_50_121
Author(s) : Holst JJ
Ref : Results Probl Cell Differ , 50 :121 , 2010
Abstract : Holst_2010_Results.Probl.Cell.Differ_50_121
ESTHER : Holst_2010_Results.Probl.Cell.Differ_50_121
PubMedSearch : Holst_2010_Results.Probl.Cell.Differ_50_121
PubMedID: 19960378

Title : Dipeptidyl peptidase-4 inhibitors administered in combination with metformin result in an additive increase in the plasma concentration of active GLP-1 - Migoya_2010_Clin.Pharmacol.Ther_88_801
Author(s) : Migoya EM , Bergeron R , Miller JL , Snyder RN , Tanen M , Hilliard D , Weiss B , Larson P , Gutierrez M , Jiang G , Liu F , Pryor KA , Yao J , Zhu L , Holst JJ , Deacon C , Herman G , Thornberry N , Amatruda J , Williams-Herman D , Wagner JA , SinhaRoy R
Ref : Clinical Pharmacology & Therapeutics , 88 :801 , 2010
Abstract : Migoya_2010_Clin.Pharmacol.Ther_88_801
ESTHER : Migoya_2010_Clin.Pharmacol.Ther_88_801
PubMedSearch : Migoya_2010_Clin.Pharmacol.Ther_88_801
PubMedID: 21048706

Title : Dipeptidyl peptidase expression during experimental colitis in mice - Yazbeck_2010_Inflamm.Bowel.Dis_16_1340
Author(s) : Yazbeck R , Sulda ML , Howarth GS , Bleich A , Raber K , von Horsten S , Holst JJ , Abbott CA
Ref : Inflamm Bowel Dis , 16 :1340 , 2010
Abstract : Yazbeck_2010_Inflamm.Bowel.Dis_16_1340
ESTHER : Yazbeck_2010_Inflamm.Bowel.Dis_16_1340
PubMedSearch : Yazbeck_2010_Inflamm.Bowel.Dis_16_1340
PubMedID: 20186930

Title : Saxagliptin: a new dipeptidyl peptidase-4 inhibitor for the treatment of type 2 diabetes - Deacon_2009_Adv.Ther_26_488
Author(s) : Deacon CF , Holst JJ
Ref : Adv Ther , 26 :488 , 2009
Abstract : Deacon_2009_Adv.Ther_26_488
ESTHER : Deacon_2009_Adv.Ther_26_488
PubMedSearch : Deacon_2009_Adv.Ther_26_488
PubMedID: 19444391

Title : Incretin-based therapy of type 2 diabetes mellitus - Knop_2009_Curr.Protein.Pept.Sci_10_46
Author(s) : Knop FK , Vilsboll T , Holst JJ
Ref : Curr Protein Pept Sci , 10 :46 , 2009
Abstract : Knop_2009_Curr.Protein.Pept.Sci_10_46
ESTHER : Knop_2009_Curr.Protein.Pept.Sci_10_46
PubMedSearch : Knop_2009_Curr.Protein.Pept.Sci_10_46
PubMedID: 19275672

Title : Immunoassays for the incretin hormones GIP and GLP-1 - Deacon_2009_Best.Pract.Res.Clin.Endocrinol.Metab_23_425
Author(s) : Deacon CF , Holst JJ
Ref : Best Pract Res Clinical Endocrinology Metab , 23 :425 , 2009
Abstract : Deacon_2009_Best.Pract.Res.Clin.Endocrinol.Metab_23_425
ESTHER : Deacon_2009_Best.Pract.Res.Clin.Endocrinol.Metab_23_425
PubMedSearch : Deacon_2009_Best.Pract.Res.Clin.Endocrinol.Metab_23_425
PubMedID: 19748060

Title : Glucagon-like peptide receptor agonists and dipeptidyl peptidase-4 inhibitors in the treatment of diabetes: a review of clinical trials - Madsbad_2008_Curr.Opin.Clin.Nutr.Metab.Care_11_491
Author(s) : Madsbad S , Krarup T , Deacon CF , Holst JJ
Ref : Curr Opin Clin Nutr Metab Care , 11 :491 , 2008
Abstract : Madsbad_2008_Curr.Opin.Clin.Nutr.Metab.Care_11_491
ESTHER : Madsbad_2008_Curr.Opin.Clin.Nutr.Metab.Care_11_491
PubMedSearch : Madsbad_2008_Curr.Opin.Clin.Nutr.Metab.Care_11_491
PubMedID: 18542012

Title : Glucagon-like peptide-1, glucose homeostasis and diabetes - Holst_2008_Trends.Mol.Med_14_161
Author(s) : Holst JJ , Deacon CF , Vilsboll T , Krarup T , Madsbad S
Ref : Trends Mol Med , 14 :161 , 2008
Abstract : Holst_2008_Trends.Mol.Med_14_161
ESTHER : Holst_2008_Trends.Mol.Med_14_161
PubMedSearch : Holst_2008_Trends.Mol.Med_14_161
PubMedID: 18353723

Title : Measurements of islet function and glucose metabolism with the dipeptidyl peptidase 4 inhibitor vildagliptin in patients with type 2 diabetes - Azuma_2008_J.Clin.Endocrinol.Metab_93_459
Author(s) : Azuma K , Radikova Z , Mancino J , Toledo FG , Thomas E , Kangani C , Dalla Man C , Cobelli C , Holst JJ , Deacon CF , He Y , Ligueros-Saylan M , Serra D , Foley JE , Kelley DE
Ref : J Clinical Endocrinology Metab , 93 :459 , 2008
Abstract : Azuma_2008_J.Clin.Endocrinol.Metab_93_459
ESTHER : Azuma_2008_J.Clin.Endocrinol.Metab_93_459
PubMedSearch : Azuma_2008_J.Clin.Endocrinol.Metab_93_459
PubMedID: 18042650

Title : Enteral nutrients potentiate the intestinotrophic action of glucagon-like peptide-2 in association with increased insulin-like growth factor-I responses in rats - Liu_2008_Am.J.Physiol.Regul.Integr.Comp.Physiol_295_R1794
Author(s) : Liu X , Murali SG , Holst JJ , Ney DM
Ref : American Journal of Physiology Regul Integr Comp Physiol , 295 :R1794 , 2008
Abstract : Liu_2008_Am.J.Physiol.Regul.Integr.Comp.Physiol_295_R1794
ESTHER : Liu_2008_Am.J.Physiol.Regul.Integr.Comp.Physiol_295_R1794
PubMedSearch : Liu_2008_Am.J.Physiol.Regul.Integr.Comp.Physiol_295_R1794
PubMedID: 18832087

Title : GLP-1: physiological effects and potential therapeutic applications - Aaboe_2008_Diabetes.Obes.Metab_10_994
Author(s) : Aaboe K , Krarup T , Madsbad S , Holst JJ
Ref : Diabetes Obes Metab , 10 :994 , 2008
Abstract : Aaboe_2008_Diabetes.Obes.Metab_10_994
ESTHER : Aaboe_2008_Diabetes.Obes.Metab_10_994
PubMedSearch : Aaboe_2008_Diabetes.Obes.Metab_10_994
PubMedID: 18435775

Title : DPP-4 inhibitor therapy: new directions in the treatment of type 2 diabetes - Deacon_2008_Front.Biosci_13_1780
Author(s) : Deacon CF , Carr RD , Holst JJ
Ref : Front Biosci , 13 :1780 , 2008
Abstract : Deacon_2008_Front.Biosci_13_1780
ESTHER : Deacon_2008_Front.Biosci_13_1780
PubMedSearch : Deacon_2008_Front.Biosci_13_1780
PubMedID: 17981667

Title : Orlistat inhibition of intestinal lipase acutely increases appetite and attenuates postprandial glucagon-like peptide-1-(7-36)-amide-1, cholecystokinin, and peptide YY concentrations - Ellrichmann_2008_J.Clin.Endocrinol.Metab_93_3995
Author(s) : Ellrichmann M , Kapelle M , Ritter PR , Holst JJ , Herzig KH , Schmidt WE , Schmitz F , Meier JJ
Ref : J Clinical Endocrinology Metab , 93 :3995 , 2008
Abstract : Ellrichmann_2008_J.Clin.Endocrinol.Metab_93_3995
ESTHER : Ellrichmann_2008_J.Clin.Endocrinol.Metab_93_3995
PubMedSearch : Ellrichmann_2008_J.Clin.Endocrinol.Metab_93_3995
PubMedID: 18647814

Title : Porcine glucagon-like peptide-2: structure, signaling, metabolism and effects - Pedersen_2008_Regul.Pept_146_310
Author(s) : Pedersen NB , Hjollund KR , Johnsen AH , Orskov C , Rosenkilde MM , Hartmann B , Holst JJ
Ref : Regul Pept , 146 :310 , 2008
Abstract : Pedersen_2008_Regul.Pept_146_310
ESTHER : Pedersen_2008_Regul.Pept_146_310
PubMedSearch : Pedersen_2008_Regul.Pept_146_310
PubMedID: 18164496

Title : The dipeptidyl peptidase IV inhibitor vildagliptin suppresses endogenous glucose production and enhances islet function after single-dose administration in type 2 diabetic patients - Balas_2007_J.Clin.Endocrinol.Metab_92_1249
Author(s) : Balas B , Baig MR , Watson C , Dunning BE , Ligueros-Saylan M , Wang Y , He YL , Darland C , Holst JJ , Deacon CF , Cusi K , Mari A , Foley JE , DeFronzo RA
Ref : J Clinical Endocrinology Metab , 92 :1249 , 2007
Abstract : Balas_2007_J.Clin.Endocrinol.Metab_92_1249
ESTHER : Balas_2007_J.Clin.Endocrinol.Metab_92_1249
PubMedSearch : Balas_2007_J.Clin.Endocrinol.Metab_92_1249
PubMedID: 17244786

Title : The physiology of glucagon-like peptide 1 - Holst_2007_Physiol.Rev_87_1409
Author(s) : Holst JJ
Ref : Physiol Rev , 87 :1409 , 2007
Abstract : Holst_2007_Physiol.Rev_87_1409
ESTHER : Holst_2007_Physiol.Rev_87_1409
PubMedSearch : Holst_2007_Physiol.Rev_87_1409
PubMedID: 17928588

Title : The dipeptidyl peptidase 4 inhibitor vildagliptin does not accentuate glibenclamide-induced hypoglycemia but reduces glucose-induced glucagon-like peptide 1 and gastric inhibitory polypeptide secretion - El-Ouaghlidi_2007_J.Clin.Endocrinol.Metab_92_4165
Author(s) : El-Ouaghlidi A , Rehring E , Holst JJ , Schweizer A , Foley J , Holmes D , Nauck MA
Ref : J Clinical Endocrinology Metab , 92 :4165 , 2007
Abstract : El-Ouaghlidi_2007_J.Clin.Endocrinol.Metab_92_4165
ESTHER : El-Ouaghlidi_2007_J.Clin.Endocrinol.Metab_92_4165
PubMedSearch : El-Ouaghlidi_2007_J.Clin.Endocrinol.Metab_92_4165
PubMedID: 17698900

Title : Effect of single oral doses of sitagliptin, a dipeptidyl peptidase-4 inhibitor, on incretin and plasma glucose levels after an oral glucose tolerance test in patients with type 2 diabetes - Herman_2006_J.Clin.Endocrinol.Metab_91_4612
Author(s) : Herman GA , Bergman A , Stevens C , Kotey P , Yi B , Zhao P , Dietrich B , Golor G , Schrodter A , Keymeulen B , Lasseter KC , Kipnes MS , Snyder K , Hilliard D , Tanen M , Cilissen C , De Smet M , De Lepeleire I , Van Dyck K , Wang AQ , Zeng W , Davies MJ , Tanaka W , Holst JJ , Deacon CF , Gottesdiener KM , Wagner JA
Ref : J Clinical Endocrinology Metab , 91 :4612 , 2006
Abstract : Herman_2006_J.Clin.Endocrinol.Metab_91_4612
ESTHER : Herman_2006_J.Clin.Endocrinol.Metab_91_4612
PubMedSearch : Herman_2006_J.Clin.Endocrinol.Metab_91_4612
PubMedID: 16912128

Title : Glucagon-like peptide-1: from extract to agent. The Claude Bernard Lecture, 2005 - Holst_2006_Diabetologia_49_253
Author(s) : Holst JJ
Ref : Diabetologia , 49 :253 , 2006
Abstract : Holst_2006_Diabetologia_49_253
ESTHER : Holst_2006_Diabetologia_49_253
PubMedSearch : Holst_2006_Diabetologia_49_253
PubMedID: 16416146

Title : The glucagon-like peptide-1 metabolite GLP-1-(9-36) amide reduces postprandial glycemia independently of gastric emptying and insulin secretion in humans - Meier_2006_Am.J.Physiol.Endocrinol.Metab_290_E1118
Author(s) : Meier JJ , Gethmann A , Nauck MA , Gotze O , Schmitz F , Deacon CF , Gallwitz B , Schmidt WE , Holst JJ
Ref : American Journal of Physiology Endocrinol Metab , 290 :E1118 , 2006
Abstract : Meier_2006_Am.J.Physiol.Endocrinol.Metab_290_E1118
ESTHER : Meier_2006_Am.J.Physiol.Endocrinol.Metab_290_E1118
PubMedSearch : Meier_2006_Am.J.Physiol.Endocrinol.Metab_290_E1118
PubMedID: 16403774

Title : The metabolite generated by dipeptidyl-peptidase 4 metabolism of glucagon-like peptide-1 has no influence on plasma glucose levels in patients with type 2 diabetes - Zander_2006_Diabetologia_49_369
Author(s) : Zander M , Madsbad S , Deacon CF , Holst JJ
Ref : Diabetologia , 49 :369 , 2006
Abstract : Zander_2006_Diabetologia_49_369
ESTHER : Zander_2006_Diabetologia_49_369
PubMedSearch : Zander_2006_Diabetologia_49_369
PubMedID: 16385384

Title : Dipeptidyl peptidase IV inhibitors: a promising new therapeutic approach for the management of type 2 diabetes - Deacon_2006_Int.J.Biochem.Cell.Biol_38_831
Author(s) : Deacon CF , Holst JJ
Ref : International Journal of Biochemistryistry & Cell Biology , 38 :831 , 2006
Abstract : Deacon_2006_Int.J.Biochem.Cell.Biol_38_831
ESTHER : Deacon_2006_Int.J.Biochem.Cell.Biol_38_831
PubMedSearch : Deacon_2006_Int.J.Biochem.Cell.Biol_38_831
PubMedID: 16242377

Title : Vildagliptin, a dipeptidyl peptidase-IV inhibitor, improves model-assessed beta-cell function in patients with type 2 diabetes - Mari_2005_J.Clin.Endocrinol.Metab_90_4888
Author(s) : Mari A , Sallas WM , He YL , Watson C , Ligueros-Saylan M , Dunning BE , Deacon CF , Holst JJ , Foley JE
Ref : J Clinical Endocrinology Metab , 90 :4888 , 2005
Abstract : Mari_2005_J.Clin.Endocrinol.Metab_90_4888
ESTHER : Mari_2005_J.Clin.Endocrinol.Metab_90_4888
PubMedSearch : Mari_2005_J.Clin.Endocrinol.Metab_90_4888
PubMedID: 15886245

Title : Neutral endopeptidase 24.11 and dipeptidyl peptidase IV are both mediators of the degradation of glucagon-like peptide 1 in the anaesthetised pig - Plamboeck_2005_Diabetologia_48_1882
Author(s) : Plamboeck A , Holst JJ , Carr RD , Deacon CF
Ref : Diabetologia , 48 :1882 , 2005
Abstract : Plamboeck_2005_Diabetologia_48_1882
ESTHER : Plamboeck_2005_Diabetologia_48_1882
PubMedSearch : Plamboeck_2005_Diabetologia_48_1882
PubMedID: 16025254

Title : Double incretin receptor knockout (DIRKO) mice reveal an essential role for the enteroinsular axis in transducing the glucoregulatory actions of DPP-IV inhibitors - Hansotia_2004_Diabetes_53_1326
Author(s) : Hansotia T , Baggio LL , Delmeire D , Hinke SA , Yamada Y , Tsukiyama K , Seino Y , Holst JJ , Schuit F , Drucker DJ
Ref : Diabetes , 53 :1326 , 2004
Abstract : Hansotia_2004_Diabetes_53_1326
ESTHER : Hansotia_2004_Diabetes_53_1326
PubMedSearch : Hansotia_2004_Diabetes_53_1326
PubMedID: 15111503

Title : On the physiology of GIP and GLP-1 - Holst_2004_Horm.Metab.Res_36_747
Author(s) : Holst JJ
Ref : Hormone & Metabolic Research , 36 :747 , 2004
Abstract : Holst_2004_Horm.Metab.Res_36_747
ESTHER : Holst_2004_Horm.Metab.Res_36_747
PubMedSearch : Holst_2004_Horm.Metab.Res_36_747
PubMedID: 15655703

Title : Improved glucose tolerance and insulin secretion by inhibition of dipeptidyl peptidase IV in mice - Ahren_2000_Eur.J.Pharmacol_404_239
Author(s) : Ahren B , Holst JJ , Martensson H , Balkan B
Ref : European Journal of Pharmacology , 404 :239 , 2000
Abstract : Ahren_2000_Eur.J.Pharmacol_404_239
ESTHER : Ahren_2000_Eur.J.Pharmacol_404_239
PubMedSearch : Ahren_2000_Eur.J.Pharmacol_404_239
PubMedID: 10980284

Title : VIP and PHI in the pig pancreas: coexistence, corelease, and cooperative effects - Holst_1987_Am.J.Physiol_252_G182
Author(s) : Holst JJ , Fahrenkrug J , Knuhtsen S , Jensen SL , Nielsen OV , Lundberg JM , Hokfelt T
Ref : American Journal of Physiology , 252 :G182 , 1987
Abstract : Holst_1987_Am.J.Physiol_252_G182
ESTHER : Holst_1987_Am.J.Physiol_252_G182
PubMedSearch : Holst_1987_Am.J.Physiol_252_G182
PubMedID: 3548423