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| Title : Structure-function studies of muscarinic acetylcholine receptors - Leach_2012_Handb.Exp.Pharmacol_208_29 |
| Author(s) : Leach K , Simms J , Sexton PM , Christopoulos A |
| Ref : Handbook of Experimental Pharmacology , :29 , 2012 |
| Abstract : Leach_2012_Handb.Exp.Pharmacol_208_29 |
| ESTHER : Leach_2012_Handb.Exp.Pharmacol_208_29 |
| PubMedSearch : Leach_2012_Handb.Exp.Pharmacol_208_29 |
| PubMedID: 22222693 |
| Title : Impact of species variability and 'probe-dependence' on the detection and in vivo validation of allosteric modulation at the M4 muscarinic acetylcholine receptor - Suratman_2011_Br.J.Pharmacol_162_1659 |
| Author(s) : Suratman S , Leach K , Sexton P , Felder CC , Loiacono R , Christopoulos A |
| Ref : British Journal of Pharmacology , 162 :1659 , 2011 |
| Abstract : Suratman_2011_Br.J.Pharmacol_162_1659 |
| ESTHER : Suratman_2011_Br.J.Pharmacol_162_1659 |
| PubMedSearch : Suratman_2011_Br.J.Pharmacol_162_1659 |
| PubMedID: 21198541 |
| Title : The role of transmembrane domain 3 in the actions of orthosteric, allosteric, and atypical agonists of the M4 muscarinic acetylcholine receptor - Leach_2011_Mol.Pharmacol_79_855 |
| Author(s) : Leach K , Davey AE , Felder CC , Sexton PM , Christopoulos A |
| Ref : Molecular Pharmacology , 79 :855 , 2011 |
| Abstract : Leach_2011_Mol.Pharmacol_79_855 |
| ESTHER : Leach_2011_Mol.Pharmacol_79_855 |
| PubMedSearch : Leach_2011_Mol.Pharmacol_79_855 |
| PubMedID: 21300722 |
| Title : Structural determinants of allosteric agonism and modulation at the M4 muscarinic acetylcholine receptor: identification of ligand-specific and global activation mechanisms - Nawaratne_2010_J.Biol.Chem_285_19012 |
| Author(s) : Nawaratne V , Leach K , Felder CC , Sexton PM , Christopoulos A |
| Ref : Journal of Biological Chemistry , 285 :19012 , 2010 |
| Abstract : Nawaratne_2010_J.Biol.Chem_285_19012 |
| ESTHER : Nawaratne_2010_J.Biol.Chem_285_19012 |
| PubMedSearch : Nawaratne_2010_J.Biol.Chem_285_19012 |
| PubMedID: 20406819 |
| Title : Molecular mechanisms of action and in vivo validation of an M4 muscarinic acetylcholine receptor allosteric modulator with potential antipsychotic properties - Leach_2010_Neuropsychopharmacology_35_855 |
| Author(s) : Leach K , Loiacono RE , Felder CC , McKinzie DL , Mogg A , Shaw DB , Sexton PM , Christopoulos A |
| Ref : Neuropsychopharmacology , 35 :855 , 2010 |
| Abstract : Leach_2010_Neuropsychopharmacology_35_855 |
| ESTHER : Leach_2010_Neuropsychopharmacology_35_855 |
| PubMedSearch : Leach_2010_Neuropsychopharmacology_35_855 |
| PubMedID: 19940843 |
| Title : New insights into the function of M4 muscarinic acetylcholine receptors gained using a novel allosteric modulator and a DREADD (designer receptor exclusively activated by a designer drug) - Nawaratne_2008_Mol.Pharmacol_74_1119 |
| Author(s) : Nawaratne V , Leach K , Suratman N , Loiacono RE , Felder CC , Armbruster BN , Roth BL , Sexton PM , Christopoulos A |
| Ref : Molecular Pharmacology , 74 :1119 , 2008 |
| Abstract : Nawaratne_2008_Mol.Pharmacol_74_1119 |
| ESTHER : Nawaratne_2008_Mol.Pharmacol_74_1119 |
| PubMedSearch : Nawaratne_2008_Mol.Pharmacol_74_1119 |
| PubMedID: 18628403 |