Family: Cutinase_like

Block: X

Parent Family: No family


This family corresponds to the Carbohydrate Esterase family CE5 in CAZy - Carbohydrate-Active enZYmes database (CE_5) (from interpro) Aerial plant organs are protected by a cuticle composed of an insoluble polymeric structural compound, cutin, which is a polyester composed of hydroxy and hydroxyepoxy fatty acids. Plant pathogenic fungi produce extracellular degradative enzymes that play an important role in pathogenesis. They include cutinase, which hydrolyses cutin, facilitating fungus penetration through the cuticle. Inhibition of the enzyme can prevent fungal infection through intact cuticles.


Interpro : IPR000675 Cutinase\/acetylxylan esterase Cutinase\/axe


Pdoc : No Pdoc

Pfam : No Pfam

Prints : No Print

EC Number : No EC Number


Peptide in Fasta
Nucleotide in Fasta
Alignment with Multalin Text only
Seed alignment with MAFFT No colour
Alignment with MAFFT No colour
Dendrogram The dnd file

No structure scheme yet for this family

No Genes Proteins

No fragment of genes

No fragment of genes

No substrate

No Inhibitor

References (6)

Title : Cutinase-like enzyme from the yeast Cryptococcus sp. strain S-2 hydrolyzes polylactic acid and other biodegradable plastics - Masaki_2005_Appl.Environ.Microbiol_71_7548
Author(s) : Masaki K , Kamini NR , Ikeda H , Iefuji H
Ref : Applied Environmental Microbiology , 71 :7548 , 2005
PubMedID: 16269800
Gene_locus related to this paper: crysp-Q874E9

Title : Multiple conformations of catalytic serine and histidine in acetylxylan esterase at 0.90 A - Ghosh_2001_J.Biol.Chem_276_11159
Author(s) : Ghosh D , Sawicki M , Lala P , Erman M , Pangborn W , Eyzaguirre J , Gutierrez R , Jornvall H , Thiel DJ
Ref : Journal of Biological Chemistry , 276 :11159 , 2001
PubMedID: 11134051
Gene_locus related to this paper: penpu-axylest

Title : Three-dimensional structure of the catalytic core of acetylxylan esterase from Trichoderma reesei: insights into the deacetylation mechanism - Hakulinen_2000_J.Struct.Biol_132_180
Author(s) : Hakulinen N , Tenkanen M , Rouvinen J
Ref : J Struct Biol , 132 :180 , 2000
PubMedID: 11243887
Gene_locus related to this paper: hypje-axylest

Title : Cloning and analysis of CUT1, a cutinase gene from Magnaporthe grisea - Sweigard_1992_Mol.Gen.Genet_232_174
Author(s) : Sweigard JA , Chumley FG , Valent B
Ref : Molecular & General Genetics , 232 :174 , 1992
PubMedID: 1557023
Gene_locus related to this paper: maggr-cutas

Title : Fusarium solani cutinase is a lipolytic enzyme with a catalytic serine accessible to solvent - Martinez_1992_Nature_356_615
Author(s) : Martinez C , de Geus P , Lauwereys M , Matthyssens G , Cambillau C
Ref : Nature , 356 :615 , 1992
PubMedID: 1560844
Gene_locus related to this paper: fusso-cutas , orysa-LPL1

Title : Structure of cutinase gene, cDNA, and the derived amino acid sequence from phytopathogenic fungi - Ettinger_1987_Biochemistry_26_7883
Author(s) : Ettinger WF , Thukral SK , Kolattukudy PE
Ref : Biochemistry , 26 :7883 , 1987
Gene_locus related to this paper: colca-cutas , colgl-cutas