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Family Report for: Hormone-sensitive_lipase_like

Hormone-sensitive_lipase_like



Relationship
Block H
Comment
Sequence similarities between hormone-sensitive lipase and prokaryotic enzymes was dicovered by Langin and Holm and Hemila et al.. The family Corresponds to the Pfam entry Abhydrolase_3. For bacterial enzymes this family correspond to family IV of the classification of Arpigny et al 1999
1 Disease(s)


Database
Sequences
Interpro
|
IPR013094 (Alpha/beta hydrolase fold-3), IPR002168 (Lipolytic enzyme), IPR033140 (Lipase_GDXG_put_SER_AS), IPR002168 (Lipase_GDXG_HIS_AS)
PIRSF
|
Pdoc
|
PFam
|
PF07859 (Abhydrolase_3)
Prints
|
Prosite
|
no EC number



Peptide in
|Fasta
Nucleotide in
|Fasta
Alignment with Multalin
|Text only/graphic display
Seed alignment with MAFFT
|No colour/coloured with Mview
Alignment with MAFFT
|No colour/coloured with Mview
Dendrogram
|Graphical display, obtained with the dnd file produced by Clustalw

References
6 more
    Title: An overview of mammalian and microbial hormone-sensitive lipases (lipolytic family IV): biochemical properties and industrial applications
    Nagaroor V, Gummadi SN
    Ref: Biotechnol Genet Eng Rev, :1, 2022 : PubMed

            

    Title: Hormone-sensitive lipase: sixty years later
    Recazens E, Mouisel E, Langin D
    Ref: Prog Lipid Res, :101084, 2020 : PubMed

            

    Title: Hormone-sensitive lipase is closely related to several bacterial proteins, and distantly related to acetylcholinesterase and lipoprotein lipase: identification of a superfamily of esterases and lipases
    Hemila H, Koivula TT, Palva I
    Ref: Biochimica & Biophysica Acta, 1210:249, 1994 : PubMed

            

Other Papers


Structure scheme for Hormone-sensitive_lipase_like

Structures in Hormone-sensitive_lipase_like family (114)

Genes Proteins in Hormone-sensitive_lipase_like family (1623)

Fragments of genes in Hormone-sensitive_lipase_like family (67)

Substrates of some enzymes in the Hormone-sensitive_lipase_like family (54)

Inhibitors of some enzymes in the Hormone-sensitive_lipase_like family (37)



Send your questions or comments to :
Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
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