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Family Report for: Pheophytinase


Block X
Parent Family : Abhydrolase_6

Pheophytin pheophorbide hydrolase (pheophytinase) is involved in chlorophyll breakdown during leaf senescence. Chlorophyllase (the other first step chrorophylle degrading enzyme) is not localized to plastids, and double knockout mutant plants still are able to degrade chlorophyll during leaf senescence. So pheophytinase is a new pathway. This entry represents a group of pheophytinases from plants, including PPH, a chloroplast-located and senescence-induced hydrolase widely distributed in algae and land plants. In Arabidopsis, PPH (also known as CRN1) specifically dephytylates the Mg-free chlorophyll pigment, pheophytin (phein), yielding pheophorbide. It plays a crucial role in Chlorophyll degradation during leaf senescence

IPR044211 (Pheophytinase, chloroplastic PPH_chloroplastic)
PF12697 (Abhydrolase_6)
no EC number

Peptide in
Nucleotide in
Alignment with Multalin
|Text only/graphic display
Seed alignment with MAFFT
|No colour/coloured with Mview
Alignment with MAFFT
|No colour/coloured with Mview
|Graphical display, obtained with the dnd file produced by Clustalw

1 more
    Title: Reverse genetic identification of CRN1 and its distinctive role in chlorophyll degradation in Arabidopsis
    Ren G, Zhou Q, Wu S, Zhang Y, Zhang L, Huang J, Sun Z, Kuai B
    Ref: J Integr Plant Biol, 52:496, 2010 : PubMed


    Title: A new chlorophyll degradation pathway
    Eckardt NA
    Ref: Plant Cell, 21:700, 2009 : PubMed


    Title: Pheophytin pheophorbide hydrolase (pheophytinase) is involved in chlorophyll breakdown during leaf senescence in Arabidopsis
    Schelbert S, Aubry S, Burla B, Agne B, Kessler F, Krupinska K, Hortensteiner S
    Ref: Plant Cell, 21:767, 2009 : PubMed


Other Papers

No structure scheme yet for this family

No Structure yet in this family

Genes Proteins in Pheophytinase family (27)

Fragments of genes in Pheophytinase family (3)

Substrates of some enzymes in the Pheophytinase family (2)

No Inhibitor

Send your questions or comments to :
Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
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