Gene_Locus Report

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Gene_locus Report for: apime-b9vmq7

Apis mellifera (Honeybee) Non-catalytic

Comment
only n-term Pfam A COesterase 95 729


Relationship
Family|Neuroligin
Block| C
Position in NCBI Life Tree|Apis mellifera
(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.)
> cellular organisms: N E > Eukaryota: N E > Opisthokonta: N E > Metazoa: N E > Eumetazoa: N E > Bilateria: N E > Protostomia: N E > Ecdysozoa: N E > Panarthropoda: N E > Arthropoda: N E > Mandibulata: N E > Pancrustacea: N E > Hexapoda: N E > Insecta: N E > Dicondylia: N E > Pterygota: N E > Neoptera: N E > Holometabola: N E > Hymenoptera: N E > Apocrita: N E > Aculeata: N E > Apoidea: N E > Apidae: N E > Apinae: N E > Apini: N E > Apis: N E > Apis mellifera: N E


Molecular evidence
Database
No mutation
No structure
No kinetic





No Substrate
No inhibitor
1 Genbank : FJ580051
1 UniProt : B9VMQ7
1 UniProt : B9VMQ7
1 Interpro : B9VMQ7
1 Pfam : B9VMQ7
1 PIRSF : B9VMQ7
1 SUPERFAM : B9VMQ7
Sequence
Graphical view for this peptide sequence: apime-b9vmq7
Colored MSA for Neuroligin (raw)
MPLPCQPAARKRPLATRSSSGSRTCLALIIAIVLLGRRGSRAATQIRYAS
RIVETKSGQIRGILQDLNSKHLDPVEVFRGIPYAAPPVGDLRFRPPISPI
PWDGIKLADSFGAVCPQHFPDISNDTAALLQMPLGRYQQLKRLYMFLTNQ
SEDCLFLNLYIPGSGSRGLEAPYAVMAYVHGESFEWGTGNIYDGSVLASA
GHVIVITLNYRLGILGFLRTRPYPDRTPGSGGNLALKDIAMGLRWVRENI
AAFGGDPTKITLIGHDTGAALVNLLLLAPYGKGLFHRVVLSSGSALSPWA
SVHDPNDLRLKVGEQIGCSTENDEDIADCLRGVPLRELMAVELPEIRFVP
RIGPGLPVDQNNPDPGLDMERASDTFIKVPLILGVSTTESNLGFNENDIQ
YGFEEDHRNRILRTFIRNAYVYHLNEIFSAVRNEYTDWDKPILHPIIIRD
STMEALSDGHTVAPLMRIAFYHARRGAKTYFYHFSHQTKESGMLQRLGSI
RGEDISYIFGLPLVGGGAFFSRNYSRQDQTVAEAVLTFFTNFAKTGNPNE
PHKIESVDYGTPKEKTRYRGLTWEQYETGIQQYLTIAMKPKMKSHYRGHK
MAVWLNLIPQLHRPGDDDVSMRHHHFRERGDHFYAGPVRDEWYTPLPLVG
TTKASASSTTACSTTTGDDSITEDITPILDDSEDDAELLQRLASRHYYST
TTALAITVGVGCILLVLNMLIFAGIYYQRDRDKKRAAMDCTPNGQESLPM
TTRSSIKAPDSPRPAQEPPPSYTTLARSPSIQEHQQIVQSQSTEVDEQFK
SEQKAGHGTSNAIHKDPIPPKPPTRTTSSLSTASGTNTIKKRVQIQEISV
Legend This sequence has been compared to family alignement (MSA)
red => minority aminoacid
blue => majority aminoacid
color intensity => conservation rate
title => sequence position(MSA position)aminoacid rate
Catalytic site
Catalytic site in the MSA

MPLPCQPAARKRPLATRSSSGSRTCLALIIAIVLLGRRGSRAATQIRYAS
RIVETKSGQIRGILQDLNSKHLDPVEVFRGIPYAAPPVGDLRFRPPISPI
PWDGIKLADSFGAVCPQHFPDISNDTAALLQMPLGRYQQLKRLYMFLTNQ
SEDCLFLNLYIPGSGSRGLEAPYAVMAYVHGESFEWGTGNIYDGSVLASA
GHVIVITLNYRLGILGFLRTRPYPDRTPGSGGNLALKDIAMGLRWVRENI
AAFGGDPTKITLIGHDTGAALVNLLLLAPYGKGLFHRVVLSSGSALSPWA
SVHDPNDLRLKVGEQIGCSTENDEDIADCLRGVPLRELMAVELPEIRFVP
RIGPGLPVDQNNPDPGLDMERASDTFIKVPLILGVSTTESNLGFNENDIQ
YGFEEDHRNRILRTFIRNAYVYHLNEIFSAVRNEYTDWDKPILHPIIIRD
STMEALSDGHTVAPLMRIAFYHARRGAKTYFYHFSHQTKESGMLQRLGSI
RGEDISYIFGLPLVGGGAFFSRNYSRQDQTVAEAVLTFFTNFAKTGNPNE
PHKIESVDYGTPKEKTRYRGLTWEQYETGIQQYLTIAMKPKMKSHYRGHK
MAVWLNLIPQLHRPGDDDVSMRHHHFRERGDHFYAGPVRDEWYTPLPLVG
TTKASASSTTACSTTTGDDSITEDITPILDDSEDDAELLQRLASRHYYST
TTALAITVGVGCILLVLNMLIFAGIYYQRDRDKKRAAMDCTPNGQESLPM
TTRSSIKAPDSPRPAQEPPPSYTTLARSPSIQEHQQIVQSQSTEVDEQFK
SEQKAGHGTSNAIHKDPIPPKPPTRTTSSLSTASGTNTIKKRVQIQEISV


References
    Title: Bridging the synaptic gap: neuroligins and neurexin I in Apis mellifera
    Biswas S, Russell RJ, Jackson CJ, Vidovic M, Ganeshina O, Oakeshott JG, Claudianos C
    Ref: PLoS ONE, 3:e3542, 2008 : PubMed

            

    Title: A deficit of detoxification enzymes: pesticide sensitivity and environmental response in the honeybee
    Claudianos C, Ranson H, Johnson RM, Biswas S, Schuler MA, Berenbaum MR, Feyereisen R, Oakeshott JG
    Ref: Insect Molecular Biology, 15:615, 2006 : PubMed

            


Other Papers


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Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
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