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aspni-hyl1

Aspergillus niger hyl1 gene, exons 1-9

Comment

Relationship

Family : Epoxide_hydrolase

Block : X

Position in NCBI Life Tree : Aspergillus niger

(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.)

> cellular organisms N E > Eukaryota N E > Opisthokonta N E > Fungi N E > Dikarya N E > Ascomycota N E > saccharomyceta N E > Pezizomycotina N E > leotiomyceta N E > Eurotiomycetes N E > Eurotiomycetidae N E > Eurotiales N E > Aspergillaceae N E > Aspergillus N E > Aspergillus niger N E

Molecular evidence

Database

Sequence

Peptide

MSAPFAKFPS SASISPNPFT VSIPDEQLDD LKTLVRLSKI APPTYESLQA DGRFGITSEW LTTMREKWLS EFDWRPFEAR LNSFPQFTTE IEGLTIHFAA LFSEREDAVP IALLHGWPGS FVEFYPILQL FREEYTPETL PFHLVVPSLP GYTFSSGPPL DKDFGLMDNA RVVDQLMKDL GFGSGYIIQG GDIGSFVGRL LGVGFDACKA VHLNLCAMRA PPEGPSIESL SAAEKEGIAR MEKFMTDGLA YAMEHSTRPS TIGHVLSSSP IALLAWIGEK YLQWVDKPLP SETILEMVSL YWLTESFPRA IHTYRETTPT ASAPNGATML QKELYIHKPF GFSFFPKDLC PVPRSWIATT GNLVFFRDHA EGGHFAALER PRELKTDLTA FVEQVWQK

References (7)

Title : Effect of Binding on Enantioselectivity of Epoxide Hydrolase - Zaugg_2018_J.Chem.Inf.Model_58_630
Author(s) : Zaugg J , Gumulya Y , Boden M , Mark AE , Malde AK
Ref : J Chem Inf Model , 58 :630 , 2018
Abstract :
PubMedSearch : Zaugg_2018_J.Chem.Inf.Model_58_630
PubMedID: 29424533
Gene_locus related to this paper: aspni-hyl1

Title : Learning epistatic interactions from sequence-activity data to predict enantioselectivity - Zaugg_2017_J.Comput.Aided.Mol.Des_31_1085
Author(s) : Zaugg J , Gumulya Y , Malde AK , Boden M
Ref : J Comput Aided Mol Des , 31 :1085 , 2017
Abstract :
PubMedSearch : Zaugg_2017_J.Comput.Aided.Mol.Des_31_1085
PubMedID: 29234997
Gene_locus related to this paper: aspni-hyl1

Title : Directed evolution of an enantioselective epoxide hydrolase: uncovering the source of enantioselectivity at each evolutionary stage - Reetz_2009_J.Am.Chem.Soc_131_7334
Author(s) : Reetz MT , Bocola M , Wang LW , Sanchis J , Cronin A , Arand M , Zou J , Archelas A , Bottalla AL , Naworyta A , Mowbray SL
Ref : Journal of the American Chemical Society , 131 :7334 , 2009
Abstract :
PubMedSearch : Reetz_2009_J.Am.Chem.Soc_131_7334
PubMedID: 19469578
Gene_locus related to this paper: aspni-hyl1

Title : Directed evolution of enantioselective enzymes: iterative cycles of CASTing for probing protein-sequence space - Reetz_2006_Angew.Chem.Int.Ed.Engl_45_1236
Author(s) : Reetz MT , Wang LW , Bocola M
Ref : Angew Chem Int Ed Engl , 45 :1236 , 2006
Abstract :
PubMedSearch : Reetz_2006_Angew.Chem.Int.Ed.Engl_45_1236
PubMedID: 16411254
Gene_locus related to this paper: aspni-hyl1

Title : Enhancing the enantioselectivity of an epoxide hydrolase by directed evolution - Reetz_2004_Org.Lett_6_177
Author(s) : Reetz MT , Torre C , Eipper A , Lohmer R , Hermes M , Brunner B , Maichele A , Bocola M , Arand M , Cronin A , Genzel Y , Archelas A , Furstoss R
Ref : Org Lett , 6 :177 , 2004
Abstract :
PubMedSearch : Reetz_2004_Org.Lett_6_177
PubMedID: 14723522
Gene_locus related to this paper: aspni-hyl1

Title : Structure of Aspergillus niger epoxide hydrolase at 1.8 A resolution: implications for the structure and function of the mammalian microsomal class of epoxide hydrolases - Zou_2000_Structure.Fold.Des_8_111
Author(s) : Zou J , Hallberg BM , Bergfors T , Oesch F , Arand M , Mowbray SL , Jones TA
Ref : Structure Fold Des , 8 :111 , 2000
Abstract :
PubMedSearch : Zou_2000_Structure.Fold.Des_8_111
PubMedID: 10673439
Gene_locus related to this paper: aspni-hyl1

Title : Cloning and molecular characterization of a soluble epoxide hydrolase from Aspergillus niger that is related to mammalian microsomal epoxide hydrolase - Arand_1999_Biochem.J_344_273
Author(s) : Arand M , Hemmer H , Durk H , Baratti J , Archelas A , Furstoss R , Oesch F
Ref : Biochemical Journal , 344 :273 , 1999
Abstract :
PubMedSearch : Arand_1999_Biochem.J_344_273
PubMedID: 10548561
Gene_locus related to this paper: aspni-hyl1