ecolx-h4unx0
Escherichia coli type VI secretion protein tle1; T6SS effector phospholipase Tle1-EAEC
Comment
Tle1EAEC has both phospholipase A1 and phospholipase A2 (PLA2) activities
Relationship
Family : T6SS-TLE1
Block : X
Position in NCBI Life Tree : Escherichia coli
(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.)
> cellular organisms N E > Bacteria N E > Proteobacteria N E > Gammaproteobacteria N E > Enterobacterales N E > Enterobacteriaceae N E > Escherichia N E > Escherichia coli N EMolecular evidence
Sequence
Peptide
VTLTIGIFFD GTGNNRENTA SRLMKFNECS AARQGVNQKD AQSCEDFLKE INKNSISNGS YRGYYSNIHW LNILYHPDQV LKKDQTSAQI KTYISGIGTA AGEADSVIGM GLGTSILDIF EGVVTKTDEA MERITQALSE FMGFNLSPDF CIAKIQFDVF GFSRGAAAAR HFANRVMEQD PAIARAIAKG LRGDFYDGKP SGEVRFLGLF DTVAAIGGIS NFFDINGRSN PGVKLELRPS VAKKVFQITA MNEYRYNFSL NSIKGMWPEL ALPGAHSDIG GGYNPVGSPL QENESLFLSC PEFEIVSDDT REM
References (2)
| Title : Structural basis for loading and inhibition of a bacterial T6SS phospholipase effector by the VgrG spike - Flaugnatti_2020_EMBO.J_39_e104129 |
| Author(s) : Flaugnatti N , Rapisarda C , Rey M , Beauvois SG , Nguyen VA , Canaan S , Durand E , Chamot-Rooke J , Cascales E , Fronzes R , Journet L |
| Ref : EMBO Journal , 39 :e104129 , 2020 |
| Abstract : |
| PubMedSearch : Flaugnatti_2020_EMBO.J_39_e104129 |
| PubMedID: 32350888 |
| Gene_locus related to this paper: ecolx-h4unx0 |
| Title : A phospholipase A1 antibacterial Type VI secretion effector interacts directly with the C-terminal domain of the VgrG spike protein for delivery - Flaugnatti_2016_Mol.Microbiol_99_1099 |
| Author(s) : Flaugnatti N , Le TT , Canaan S , Aschtgen MS , Nguyen VS , Blangy S , Kellenberger C , Roussel A , Cambillau C , Cascales E , Journet L |
| Ref : Molecular Microbiology , 99 :1099 , 2016 |
| Abstract : |
| PubMedSearch : Flaugnatti_2016_Mol.Microbiol_99_1099 |
| PubMedID: 26714038 |
| Gene_locus related to this paper: ecolx-h4unx0 |