floch-rads2

Floropilus chiversii (Chaetomium chiversii). Radicicol biosynthesis cluster protein s2. ccradS2 Thioesterase domain

Comment

Relationship

Family : Thioesterase

Block : X

Position in NCBI Life Tree : Floropilus chiversii

Molecular evidence

No mutation

No structure

No kinetic

No disease

No substrate

No inhibitor

Database

Sequence

Peptide

FEVIIQTIAI ETGMDTSELT DDSALADLGV DSIMAIEVAA RVSNATGREL TPSFVSEYPT IGDLRRAFAM APSSSSSTSA SESVSESLDD SSSTSRSATP SSSMKETEAG FVEDDSLRKK PVISAAAAVV TAAGVAETQA TKVQPQAPAA TAADNDSSPA PSVRIMLLQG RPAKSRGAAD GSHAPPPFYM IADGTGSIAT YIHLASSLQS KMPIYGIDSP FLRCPDRLTP EVGIPGAARL IVDALLKKQP DKDVPFWIGG FSGGAMVAYE VCRQLSAAGR PVDGLLLIDM CAPRQVAAVP EDDGEVGLAM FDAVSGQDES GVWSATDGTR RHLGAMFSCV ATYNPEPLPP RGGGNTPAKR AAMIWARKGM IDRCVSSVRF RQMLADRGIS PEPYPGFMED PKLGAVAWSL PHKTGADLGP NGWERYLGGD RLLCMSIEAD HLEMPTPGYA QLLGETMDKA FRYFRDGLMD

References

Title : Rational reprogramming of fungal polyketide first-ring cyclization - Xu_2013_Proc.Natl.Acad.Sci.U.S.A_110_5398
Author(s) : Xu Y , Zhou T , Zhou Z , Su S , Roberts SA , Montfort WR , Zeng J , Chen M , Zhang W , Lin M , Zhan J , Molnar I
Ref : Proc Natl Acad Sci U S A , 110 :5398 , 2013
Abstract : Xu_2013_Proc.Natl.Acad.Sci.U.S.A_110_5398
ESTHER : Xu_2013_Proc.Natl.Acad.Sci.U.S.A_110_5398
PubMedSearch : Xu_2013_Proc.Natl.Acad.Sci.U.S.A_110_5398
PubMedID: 23509261
Gene_locus related to this paper: aspte-curs2 , floch-rads2

Title : Thioesterase domains of fungal nonreducing polyketide synthases act as decision gates during combinatorial biosynthesis - Xu_2013_J.Am.Chem.Soc_135_10783
Author(s) : Xu Y , Zhou T , Zhang S , Xuan LJ , Zhan J , Molnar I
Ref : Journal of the American Chemical Society , 135 :10783 , 2013
Abstract : Xu_2013_J.Am.Chem.Soc_135_10783
ESTHER : Xu_2013_J.Am.Chem.Soc_135_10783
PubMedSearch : Xu_2013_J.Am.Chem.Soc_135_10783
PubMedID: 23822773
Gene_locus related to this paper: aspte-curs2 , floch-rads2

Title : Functional characterization of the biosynthesis of radicicol, an Hsp90 inhibitor resorcylic acid lactone from Chaetomium chiversii - Wang_2008_Chem.Biol_15_1328
Author(s) : Wang S , Xu Y , Maine EA , Wijeratne EM , Espinosa-Artiles P , Gunatilaka AA , Molnar I
Ref : Chemical Biology , 15 :1328 , 2008
Abstract : Wang_2008_Chem.Biol_15_1328
ESTHER : Wang_2008_Chem.Biol_15_1328
PubMedSearch : Wang_2008_Chem.Biol_15_1328
PubMedID: 19101477
Gene_locus related to this paper: floch-rads2