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geose-q93a71

Geobacillus stearothermophilus (Bacillus stearothermophilus) T6 lipase

Comment

Relationship

Family : Bacterial_lip_FamI.5

Block : L

Position in NCBI Life Tree : Geobacillus stearothermophilus

(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.)

> cellular organisms N E > Bacteria N E > Terrabacteria group N E > Firmicutes N E > Bacilli N E > Bacillales N E > Bacillaceae N E > Geobacillus N E > Geobacillus stearothermophilus N E

Molecular evidence

No mutation

4FMP - Crystal structure of thermostable, organic-solvent tolerant lipase from Geobacillus sp. strain ARM A0MTM1 4X6U - Crystal Structure of lipase from Geobacillus stearothermophilus T6 4X71 - Crystal Structure of lipase from Geobacillus stearothermophilus T6 methanol stable variant A269T 4X7B - Crystal Structure of lipase from Geobacillus stearothermophilus T6 methanol stable variant H86Y\/A269T 4X85 - Crystal Structure of lipase from Geobacillus stearothermophilus T6 methanol stable variant H86Y\/A269T\/R374W 6FZ1 - Crystal Structure of lipase from Geobacillus stearothermophilus T6 methanol stable variant L360F 6FZ7 - Crystal Structure of lipase from Geobacillus stearothermophilus T6 methanol stable variant L184F 6FZ8 - Crystal Structure of lipase from Geobacillus stearothermophilus T6 methanol stable variant L184F\/A187F 6FZ9 - Crystal Structure of lipase from Geobacillus stearothermophilus T6 methanol stable variant A187F\/L360F 6FZA - Crystal Structure of lipase from Geobacillus stearothermophilus T6 methanol stable variant A187FL360F 6FZC - Crystal Structure of lipase from Geobacillus stearothermophilus T6 methanol stable variant L184F\/L360F 6FZD - Crystal Structure of lipase from Geobacillus stearothermophilus T6 methanol stable variant L184F\/A187F\/L360F 6S3G - Crystal Structure of lipase from Geobacillus stearothermophilus T6 variant A187C\/F291C 6S3J - Crystal Structure of lipase from Geobacillus stearothermophilus T6 variant E134C\/F149C 6S3V - Crystal Structure of lipase from Geobacillus stearothermophilus T6 variant E251C\/G332C

No kinetic

No disease

No substrate

No inhibitor

Database

Sequence

Peptide

MMKCCRRVAL VLLGLWFVFC ISVLGGRAEA AASRANDAPI VLLHGFTGWG REEMFGFKYW GGVRGDIEQW LNDNGYRTYT LAVGPLSSNW DRACEAYAQL VGGTVDYGAA HAAKHGHARF GRTYPGLLPE LKRGGRIHII AHSQGGQTAR MLVSLLENGS QEEREYAKAH NVSLSPLFEG GHHFVLSVTT IATPHDGTTL VNMVDFTDRF FDLQKAVLKA AAVASNVPYT SQVYDFKLDQ WGLRRQPGES FDQYFERLKR SPVWTSTDTA RYDLSVPGAE KLNQWVKASP NTYYLSFATE RTYRGALTGN YYPELGMNAF SAVVCAPFLG SYRNATLGID DRWLENDGIV NTFSMNGPKR GSTDRIVPYD GTIKKGVWND MGTYNVDHLE VIGVDPNPLF DIRAFYLRLA EQLASLQP

References (7)

Title : Bridges to Stability: Engineering Disulfide Bonds Towards Enhanced Lipase Biodiesel Synthesis - Gihaz_2020_ChemCatChem_12_181
Author(s) : Gihaz S , Bash Y , Rush I , Shahar A , Pazy Y , Fishman A
Ref : ChemCatChem , 12 :181 , 2020
Abstract :
PubMedSearch : Gihaz_2020_ChemCatChem_12_181
PubMedID:
Gene_locus related to this paper: geose-q93a71

Title : Filling the Void: Introducing Aromatic Interactions into Solvent Tunnels To Enhance Lipase Stability in Methanol - Gihaz_2018_Appl.Environ.Microbiol_84_
Author(s) : Gihaz S , Kanteev M , Pazy Y , Fishman A
Ref : Applied Environmental Microbiology , 84 : , 2018
Abstract :
PubMedSearch : Gihaz_2018_Appl.Environ.Microbiol_84_
PubMedID: 30217852
Gene_locus related to this paper: geose-q93a71

Title : Creating an Efficient Methanol-Stable Biocatalyst by Protein and Immobilization Engineering Steps towards Efficient Biosynthesis of Biodiesel - Gihaz_2016_ChemSusChem_9_3161
Author(s) : Gihaz S , Weiser D , Dror A , Satorhelyi P , Jerabek-Willemsen M , Poppe L , Fishman A
Ref : ChemSusChem , 9 :3161 , 2016
Abstract :
PubMedSearch : Gihaz_2016_ChemSusChem_9_3161
PubMedID: 27778473
Gene_locus related to this paper: geose-q93a71

Title : Structural insights into methanol-stable variants of lipase T6 from Geobacillus stearothermophilus - Dror_2015_Appl.Microbiol.Biotechnol_99_9449
Author(s) : Dror A , Kanteev M , Kagan I , Gihaz S , Shahar A , Fishman A
Ref : Applied Microbiology & Biotechnology , 99 :9449 , 2015
Abstract :
PubMedSearch : Dror_2015_Appl.Microbiol.Biotechnol_99_9449
PubMedID: 26026940
Gene_locus related to this paper: geose-q93a71

Title : Protein Engineering by Random Mutagenesis and Structure-Guided Consensus of Geobacillus stearothermophilus Lipase T6 for Enhanced Stability in Methanol - Dror_2014_Appl.Environ.Microbiol_80_1515
Author(s) : Dror A , Shemesh E , Dayan N , Fishman A
Ref : Applied Environmental Microbiology , 80 :1515 , 2014
Abstract :
PubMedSearch : Dror_2014_Appl.Environ.Microbiol_80_1515
PubMedID: 24362426
Gene_locus related to this paper: geose-q93a71

Title : Isolation and identification of lipase producing thermophilic Geobacillus sp. SBS-4S: cloning and characterization of the lipase - Tayyab_2011_J.Biosci.Bioeng_111_272
Author(s) : Tayyab M , Rashid N , Akhtar M
Ref : J Biosci Bioeng , 111 :272 , 2011
Abstract :
PubMedSearch : Tayyab_2011_J.Biosci.Bioeng_111_272
PubMedID: 21185780
Gene_locus related to this paper: geose-q93a71

Title : High level expression and characterization of a novel thermostable, organic solvent tolerant, 1,3-regioselective lipase from Geobacillus sp. strain ARM - Ebrahimpour_2011_Bioresour.Technol_102_6972
Author(s) : Ebrahimpour A , Rahman RNZRA , Basri M , Salleh AB
Ref : Bioresour Technol , 102 :6972 , 2011
Abstract :
PubMedSearch : Ebrahimpour_2011_Bioresour.Technol_102_6972
PubMedID: 21531550
Gene_locus related to this paper: bacsp-lip , geose-q93a71