human-PPT2
Homo sapiens (Human) 34.9 kda protein (palmitoyl-protein thioesterase-2)
Comment
A second form inactive is known Trembl 014799 genbank AF020544 differs by yhe C-terminal end
Relationship
Family : Palmitoyl-protein_thioesterase
Block : X
Position in NCBI Life Tree : Homo sapiens
(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.)
> cellular organisms N E > Eukaryota N E > Opisthokonta N E > Metazoa N E > Eumetazoa N E > Bilateria N E > Deuterostomia N E > Chordata N E > Craniata N E > Vertebrata N E > Gnathostomata N E > Teleostomi N E > Euteleostomi N E > Sarcopterygii N E > Dipnotetrapodomorpha N E > Tetrapoda N E > Amniota N E > Mammalia N E > Theria N E > Eutheria N E > Boreoeutheria N E > Euarchontoglires N E > Primates N E > Haplorrhini N E > Simiiformes N E > Catarrhini N E > Hominoidea N E > Hominidae N E > Homininae N E > Homo N E > Homo sapiens N EMolecular evidence
Database
Sequence
Peptide
MLGLWGQRLP AAWVLLLLPF LPLLLLAAPA PHRASYKPVI VVHGLFDSSY SFRHLLEYIN ETHPGTVVTV LDLFDGRESL RPLWEQVQGF REAVVPIMAK APQGVHLICY SQGGLVCRAL LSVMDDHNVD SFISLSSPQM GQYGDTDYLK WLFPTSMRSN LYRICYSPWG QEFSICNYWH DPHHDDLYLN ASSFLALING ERDHPNATVW RKNFLRVGHL VLIGGPDDGV ITPWQSSFFG FYDANETVLE MEEQLVYLRD SFGLKTLLAR GAIVRCPMAG ISHTAWHSNR TLYETCIEPW LS
References (4)
| Title : The crystal structure of palmitoyl protein thioesterase-2 (PPT2) reveals the basis for divergent substrate specificities of the two lysosomal thioesterases, PPT1 and PPT2 - Calero_2003_J.Biol.Chem_278_37957 |
| Author(s) : Calero G , Gupta P , Nonato MC , Tandel S , Biehl ER , Hofmann SL , Clardy J |
| Ref : Journal of Biological Chemistry , 278 :37957 , 2003 |
| Abstract : |
| PubMedSearch : Calero_2003_J.Biol.Chem_278_37957 |
| PubMedID: 12855696 |
| Gene_locus related to this paper: human-PPT2 |
| Title : Characterization of a human MHC class III region gene product with S-thioesterase activity - Aguado_1999_Biochem.J_341 ( Pt 3)_679 |
| Author(s) : Aguado B , Campbell RD |
| Ref : Biochemical Journal , 341 ( Pt 3) :679 , 1999 |
| Abstract : |
| PubMedSearch : Aguado_1999_Biochem.J_341 ( Pt 3)_679 |
| PubMedID: 10417332 |
| Gene_locus related to this paper: human-PPT2 |
| Title : Structure of the human palmitoyl-protein thioesterase-2 gene (PPT2) in the major histocompatibility complex on chromosome 6p21.3 - Soyombo_1999_Genomics_56_208 |
| Author(s) : Soyombo AA , Yi W , Hofmann SL |
| Ref : Genomics , 56 :208 , 1999 |
| Abstract : |
| PubMedSearch : Soyombo_1999_Genomics_56_208 |
| PubMedID: 10051407 |
| Gene_locus related to this paper: human-PPT2 |
| Title : Molecular cloning and expression of palmitoyl-protein thioesterase 2 (PPT2), a homolog of lysosomal palmitoyl-protein thioesterase with a distinct substrate specificity - Soyombo_1997_J.Biol.Chem_272_27456 |
| Author(s) : Soyombo AA , Hofmann SL |
| Ref : Journal of Biological Chemistry , 272 :27456 , 1997 |
| Abstract : |
| PubMedSearch : Soyombo_1997_J.Biol.Chem_272_27456 |
| PubMedID: 9341199 |
| Gene_locus related to this paper: human-PPT2 |