hyaaz-ACHE1

Hyalella azteca (Amphipod) acetylcholinesterase ace-1, partial

Comment

p.Gly119Ser The nontarget amphipod populations have become resistant to Organophosphate and carbamate insecticides. The terrestrial application of pesticides has provided strong selective pressures to drive evolution in a nontarget, aquatic species

Relationship

Family : ACHE

Block : C

Position in NCBI Life Tree : Hyalella azteca

(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.)

> cellular organisms N E > Eukaryota N E > Opisthokonta N E > Metazoa N E > Eumetazoa N E > Bilateria N E > Protostomia N E > Ecdysozoa N E > Panarthropoda N E > Arthropoda N E > Mandibulata N E > Pancrustacea N E > Crustacea N E > Malacostraca N E > Eumalacostraca N E > Multicrustacea N E > Peracarida N E > Amphipoda N E > Senticaudata N E > Talitrida N E > Talitroidea N E > Hyalellidae N E > Hyalella N E > Hyalella azteca N E

Molecular evidence

No mutation

No structure

No kinetic

No disease

No substrate

No inhibitor

Database

Sequence

Peptide

MWCRYLVLAL VFTLGTSALH DPLVVNTRKG KVKGKTVKTA LGGEVDAWYS IPFAKPPVGD LRFRHPIPID RWHDVKDATE LPNSCWQTLD DFFGNFEGST MWNANTPMSE DCLYLSIIVP KPRPTNVPVL VWIYGGGFYS GTSSLEVYDY RTLADNQNVI IVAPHYRIAS LGFLYMGTPD VPGNTGLFDQ LMALEWIKDN IEFFGGNPNN ITLMGESAGA TSISMLLLSP LSRNLFSQAI MQSGSATVPW GIMSKKENML RGQRLAEAVG CPTDMSNPSV VIDCLRSKNA SELVNSETSN GVTDFPFVPI IDGAFFDKLP IEYLRNGDFK KCNILMGSNT EEGYWFIMYF LPSLFRREEN VLITRAEFER SVRALFPYFN ELILQAIMYQ YTDWIDPEDG AKNRNAIDKM IGDYHFTCNV NEFAEYYSKS GNNVYMYYFK HRSSGSKWPK WTGVLHADEI SFLFGQPLNP KYTTFTEVEQ DLSRQMMTYW GNFIKTGNPS EGDHRSFAKT KWPLYSPATK EYLILSGEES GLGRGPRLKE CAFWKSFLPQ LVKHSGEIWP VVK

References (2)

Title : Development of insecticide resistance in Hyalella azteca - Gamble_2023_Environ.Pollut_322_121165
Author(s) : Gamble NE , Huff Hartz KE , Figuero AE , Poynton HC , Lydy MJ
Ref : Environ Pollut , :121165 , 2023
PubMedID: 36720337
Gene_locus related to this paper: hyaaz-ACHE1

Title : The G119S ace-1 mutation confers adaptive organophosphate resistance in a nontarget amphipod - Major_2020_Evol.Appl_13_620
Author(s) : Major KM , Weston DP , Lydy MJ , Huff Hartz KE , Wellborn GA , Manny AR , Poynton HC
Ref : Evol Appl , 13 :620 , 2020
PubMedID: 32211056
Gene_locus related to this paper: hyaaz-ACHE1