pseff-p9wes9

Pseudevernia furfuracea (Tree moss) Non-reducing polyketide synthase PFUR17_0229 Lecanoric acid synthase thioesterase domain

Comment

The biosynthesis occurs via the formation of 2 orsellinate intermediates fused together by the C-terminal thioesterase (TE) domain that finally releases lecanoric acid. The same reaction is performed by thioesterase domain of PKS but homologous to BD-FAE family

Relationship

Family : Thioesterase

Block : X

Position in NCBI Life Tree : Pseudevernia furfuracea

Molecular evidence

No mutation

No structure

No kinetic

No disease

No inhibitor

Database

No Genbank

Sequence

Peptide

DLGVDSLLTI SILDSFKSEM RMSLAATFFH ENPTFTDVQK ALGVPSMPQK SLKMPSEFPE MNMGPSNQSV RSKSSILQGR PASNRPALFL LPDGAGSMFS YISLPALPSG VPVYGLDSPF HNSPKDYTVS FEEVASIFIK EIRAIQPRGP YMLGGWSLGG ILAYEASRQL IAQGETITNL IMIDSPCPGT LPPLPSPTLN LLEKAGIFDG LSASSGPITE RTRLHFLGSV RALENYTVKP IPADRSPGKV TVIWAQDGVL EGREDVGGEE WMADSSGGDA NADMEKAKQW LTGKRTSFGP SGWDKLTGAE VQCHVVGGNH FSIMFPPKIE AVAVAMATGL PA

References

Title : Identification of a lichen depside polyketide synthase gene by heterologous expression in Saccharomyces cerevisiae - Kealey_2021_Metab.Eng.Commun_13_e00172
Author(s) : Kealey JT , Craig JP , Barr PJ
Ref : Metab Eng Commun , 13 :e00172 , 2021
Abstract : Kealey_2021_Metab.Eng.Commun_13_e00172
ESTHER : Kealey_2021_Metab.Eng.Commun_13_e00172
PubMedSearch : Kealey_2021_Metab.Eng.Commun_13_e00172
PubMedID: 34430202
Gene_locus related to this paper: pseff-p9wes9

Title : Biosynthetic Gene Content of the 'Perfume Lichens' Evernia prunastri and Pseudevernia furfuracea - Calchera_2019_Molecules_24_203
Author(s) : Calchera A , Dal Grande F , Bode HB , Schmitt I
Ref : Molecules , 24 :203 , 2019
Abstract : Calchera_2019_Molecules_24_203
ESTHER : Calchera_2019_Molecules_24_203
PubMedSearch : Calchera_2019_Molecules_24_203
PubMedID: 30626017
Gene_locus related to this paper: pseff-p9wes9