Orsellinate
Lecanoric-acid is the product of association of two orsellinate molecules. The biosynthesis probably occurs via the formation of 2 orsellinate intermediates fused together by the C-terminal thioesterase (TE) domain that finally releases lecanoric acid. The same reaction is performed by thioesterase domain of PKS either belonging to BD-FAE or to the thoesterase family. Inhibitor of histidine decarboxylase
General
Type : Natural
Chemical_Nomenclature : 2,4-dihydroxy-6-methylbenzoic acid
Canonical SMILES : CC1=CC(=CC(=C1C(=O)O)O)O
InChI : InChI=1S\/C8H8O4\/c1-4-2-5(9)3-6(10)7(4)8(11)12\/h2-3,9-10H,1H3,(H,11,12)
InChIKey : AMKYESDOVDKZKV-UHFFFAOYSA-N
Other name(s) : Orsellinic acid || o-Orsellinic acid || Orsellic acid
MW : 168.15
Formula : C8H8O4
CAS_number : 480-64-8
PubChem : 68072
UniChem : AMKYESDOVDKZKV-UHFFFAOYSA-N
Target
Structures : No structure
Families : Thioesterase, BD-FAE
References (2)
| Title : Genomic virulence features of Beauveria bassiana as a biocontrol agent for the mountain pine beetle population - Li_2023_BMC.Genomics_24_390 |
| Author(s) : Li JX , Fernandez KX , Ritland C , Jancsik S , Engelhardt DB , Coombe L , Warren RL , van Belkum MJ , Carroll AL , Vederas JC , Bohlmann J , Birol I |
| Ref : BMC Genomics , 24 :390 , 2023 |
| Abstract : |
| PubMedSearch : Li_2023_BMC.Genomics_24_390 |
| PubMedID: 37430186 |
| Title : Fungal biosynthesis of the bibenzoquinone oosporein to evade insect immunity - Feng_2015_Proc.Natl.Acad.Sci.U.S.A_112_11365 |
| Author(s) : Feng P , Shang Y , Cen K , Wang C |
| Ref : Proc Natl Acad Sci U S A , 112 :11365 , 2015 |
| Abstract : |
| PubMedSearch : Feng_2015_Proc.Natl.Acad.Sci.U.S.A_112_11365 |
| PubMedID: 26305932 |
| Gene_locus related to this paper: beab2-ops1 |