strpu-rdmC
Streptomyces purpurascens ATCC 25489 aclacinomycin methylesterase RdmC (rdmC)
Comment
rdmc protein possible C-C hydrolase
Relationship
Family : Aclacinomycin-methylesterase_RdmC
Block : X
Position in NCBI Life Tree : Streptomyces purpurascens
(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.)
> cellular organisms N E > Bacteria N E > Terrabacteria group N E > Actinobacteria [phylum] N E > Actinobacteria [class] N E > Streptomycetales N E > Streptomycetaceae N E > Streptomyces N E > Streptomyces purpurascens N E > cellular organisms N E > Bacteria N E > Terrabacteria group N E > Actinobacteria [phylum] N E > Actinobacteria [class] N E > Streptomycetales N E > Streptomycetaceae N E > Streptomyces N E > Streptomyces purpurascens N E > cellular organisms N E > Bacteria N E > Terrabacteria group N E > Actinobacteria [phylum] N E > Actinobacteria [class] N E > Streptomycetales N E > Streptomycetaceae N E > Streptomyces N E > Streptomyces purpurascens N EMolecular evidence
No mutation
1Q0R - Crystal structure of aclacinomycin methylesterase (RdmC) with bound product analogue, 10-decarboxymethylaclacinomycin T (DcmaT)
1Q0R - Crystal structure of aclacinomycin methylesterase (RdmC) with bound product analogue, 10-decarboxymethylaclacinomycin T (DcmaT)
1Q0R - Crystal structure of aclacinomycin methylesterase (RdmC) with bound product analogue, 10-decarboxymethylaclacinomycin T (DcmaT)
1Q0Z - Crystal structure of aclacinomycin methylesterase (RdmC) with bound product analogue, 10-decarboxymethylaclacinomycin A (DcmA)
1Q0Z - Crystal structure of aclacinomycin methylesterase (RdmC) with bound product analogue, 10-decarboxymethylaclacinomycin A (DcmA)
1Q0Z - Crystal structure of aclacinomycin methylesterase (RdmC) with bound product analogue, 10-decarboxymethylaclacinomycin A (DcmA)
No kinetic
No disease
Sequence
Peptide
MSERIVPSGD VELWSDDFGD PADPALLLVM GGNLSALGWP DEFARRLADG GLHVIRYDHR DTGRSTTRDF AAHPYGFGEL AADAVAVLDG WGVDRAHVVG LSMGATITQV IALDHHDRLS SLTMLLGGGL DIDFDANIER VMRGEPTLDG LPGPQQPFLD ALALMNQPAE GRAAEVAKRV SKWRILSGTG VPFDDAEYAR WEERAIDHAG GVLAEPYAHY SLTLPPPSRA AELREVTVPT LVIQAEHDPI APAPHGKHLA GLIPTARLAE IPGMGHALPS SVHGPLAEVI LAHTRSAA
References (9)
| Title : Crystal structure of aclacinomycin methylesterase with bound product analogues: implications for anthracycline recognition and mechanism - Jansson_2003_J.Biol.Chem_278_39006 |
| Author(s) : Jansson A , Niemi J , Mantsala P , Schneider G |
| Ref : Journal of Biological Chemistry , 278 :39006 , 2003 |
| Abstract : |
| PubMedSearch : Jansson_2003_J.Biol.Chem_278_39006 |
| PubMedID: 12878604 |
| Gene_locus related to this paper: ecoli-rdmC , strpu-rdmC |
| Title : Crystal structure of aclacinomycin methylesterase with bound product analogues: implications for anthracycline recognition and mechanism - Jansson_2003_J.Biol.Chem_278_39006 |
| Author(s) : Jansson A , Niemi J , Mantsala P , Schneider G |
| Ref : Journal of Biological Chemistry , 278 :39006 , 2003 |
| Abstract : |
| PubMedSearch : Jansson_2003_J.Biol.Chem_278_39006 |
| PubMedID: 12878604 |
| Gene_locus related to this paper: ecoli-rdmC , strpu-rdmC |
| Title : Crystal structure of aclacinomycin methylesterase with bound product analogues: implications for anthracycline recognition and mechanism - Jansson_2003_J.Biol.Chem_278_39006 |
| Author(s) : Jansson A , Niemi J , Mantsala P , Schneider G |
| Ref : Journal of Biological Chemistry , 278 :39006 , 2003 |
| Abstract : |
| PubMedSearch : Jansson_2003_J.Biol.Chem_278_39006 |
| PubMedID: 12878604 |
| Gene_locus related to this paper: ecoli-rdmC , strpu-rdmC |
| Title : Nucleotide sequences and expression of genes from Streptomyces purpurascens that cause the production of new anthracyclines in Streptomyces galilaeus - Niemi_1995_J.Bacteriol_177_2942 |
| Author(s) : Niemi J , Mantsala P |
| Ref : Journal of Bacteriology , 177 :2942 , 1995 |
| Abstract : |
| PubMedSearch : Niemi_1995_J.Bacteriol_177_2942 |
| PubMedID: 7751313 |
| Gene_locus related to this paper: strpu-rdmC |
| Title : Nucleotide sequences and expression of genes from Streptomyces purpurascens that cause the production of new anthracyclines in Streptomyces galilaeus - Niemi_1995_J.Bacteriol_177_2942 |
| Author(s) : Niemi J , Mantsala P |
| Ref : Journal of Bacteriology , 177 :2942 , 1995 |
| Abstract : |
| PubMedSearch : Niemi_1995_J.Bacteriol_177_2942 |
| PubMedID: 7751313 |
| Gene_locus related to this paper: strpu-rdmC |
| Title : Nucleotide sequences and expression of genes from Streptomyces purpurascens that cause the production of new anthracyclines in Streptomyces galilaeus - Niemi_1995_J.Bacteriol_177_2942 |
| Author(s) : Niemi J , Mantsala P |
| Ref : Journal of Bacteriology , 177 :2942 , 1995 |
| Abstract : |
| PubMedSearch : Niemi_1995_J.Bacteriol_177_2942 |
| PubMedID: 7751313 |
| Gene_locus related to this paper: strpu-rdmC |
| Title : Hybrid anthracycline antibiotics: production of new anthracyclines by cloned genes from Streptomyces purpurascens in Streptomyces galilaeus - Niemi_1994_Microbiology_140_1351 |
| Author(s) : Niemi J , Ylihonko K , Hakala J , Parssinen R , Kopio A , Mantsala P |
| Ref : Microbiology , 140 :1351 , 1994 |
| Abstract : |
| PubMedSearch : Niemi_1994_Microbiology_140_1351 |
| PubMedID: 8081500 |
| Gene_locus related to this paper: strpu-rdmC |
| Title : Hybrid anthracycline antibiotics: production of new anthracyclines by cloned genes from Streptomyces purpurascens in Streptomyces galilaeus - Niemi_1994_Microbiology_140_1351 |
| Author(s) : Niemi J , Ylihonko K , Hakala J , Parssinen R , Kopio A , Mantsala P |
| Ref : Microbiology , 140 :1351 , 1994 |
| Abstract : |
| PubMedSearch : Niemi_1994_Microbiology_140_1351 |
| PubMedID: 8081500 |
| Gene_locus related to this paper: strpu-rdmC |
| Title : Hybrid anthracycline antibiotics: production of new anthracyclines by cloned genes from Streptomyces purpurascens in Streptomyces galilaeus - Niemi_1994_Microbiology_140_1351 |
| Author(s) : Niemi J , Ylihonko K , Hakala J , Parssinen R , Kopio A , Mantsala P |
| Ref : Microbiology , 140 :1351 , 1994 |
| Abstract : |
| PubMedSearch : Niemi_1994_Microbiology_140_1351 |
| PubMedID: 8081500 |
| Gene_locus related to this paper: strpu-rdmC |