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Aclacinomycin-methylesterase_RdmC

Relationship

Family: Aclacinomycin-methylesterase_RdmC

Block: X

Parent Family: Abhydrolase_6

Comment

PIRSF037216 Aclacinomycin methylesterase (RdmC) is one of the tailoring enzymes that modify the aklavinone skeleton in the biosynthesis of anthracyclines in Streptomyces species. alcbs-q0vlq1 EH83 is a polyacetic acid hydrolase. Also contains the macrolide esterase EstX

Database

Interpro : IPR000073 Alpha\/beta hydrolase fold-1

PIRSF : PIRSF037216

Pdoc : No Pdoc

Pfam : PF12697 Abhydrolase_6

Prints : No Print

EC Number : 3.1.1.95

Sequences

Peptide in Fasta
Nucleotide in Fasta
Alignment with Multalin Text only
Seed alignment with MAFFT No colour / coloured with Mview
Alignment with MAFFT No colour / coloured with Mview
Dendrogram The dnd file

Structure Name Proteins
1Q0R Crystal structure of aclacinomycin methylesterase (RdmC) with bound product analogue, 10-decarboxymethylaclacinomycin T (DcmaT) strpu-rdmC
1Q0Z Crystal structure of aclacinomycin methylesterase (RdmC) with bound product analogue, 10-decarboxymethylaclacinomycin A (DcmA) strpu-rdmC
8PZG Metagenomic lipase ORF17 9bact-ORF17.8PZG

Gene_locus Name Species
9acto-b5g999 Streptomyces sp. SPB74 Carboxyl esterase Streptomyces sp. SPB74
9acto-b5hp47 Streptomyces sviceus ATCC 29083 Putative uncharacterized protein Streptomyces sviceus ATCC 29083
9acto-d1xnm4 Streptomyces sp. ACTE Alpha\/beta hydrolase fold protein Streptomyces sp. ACTE
9acto-d3ctl7 Frankia sp. EUN1f Alpha\/beta hydrolase fold protein Frankia sp. EUN1f
9acto-d3cww2 Frankia sp. EUN1f Alpha\/beta hydrolase fold protein Frankia sp. EUN1f
9acto-d3m5d4 Frankia symbiont of Datisca glomerata Alpha\/beta hydrolase fold protein Frankia symbiont of Datisca glomerata
9alte-a6f626 Marinobacter algicola DG893 Predicted Hydrolase or acyltransferase (Alpha\/beta hydrolase superfamily) protein Marinobacter algicola DG893
9bact-ORF17.8PZG uncultured bacterium Metagenomic lipase ORF17 uncultured bacteria
9bact-a9ukk2 uncultured bacterium Lipase\/esterase uncultured bacterium
9bact-b0l3i3 uncultured bacterium Lipase\/esterase uncultured bacterium
9bact-b8y566 uncultured bacterium Lipolytic enzyme uncultured bacterium
9bact-c3rww3 uncultured bacterium Putative lipase\/esterase uncultured bacterium
9bact-estC55.197 uncultured bacterium. Lipolytic protein uncultured bacterium
9bact-g3c5s9 uncultured bacterium. Lipase\/esterase uncultured bacterium
9bact-g3c5t0 uncultured bacterium. Lipase\/esterase uncultured bacterium
9burk-a6gu41 Limnobacter sp. MED105 Alpha\/beta hydrolase superfamily protein interrupted gene pseudogene Limnobacter sp. MED105
9burk-c9y9d4 Curvibacter putative symbiont of Hydra magnipapillata Putative uncharacterized protein Curvibacter putative symbiont of Hydra magnipapillata
9delt-q5md37 Cystobacter fuscus hypothetical protein Cystobacter fuscus
9entr-b6xhq2 Providencia alcalifaciens DSM 30120 Putative uncharacterized protein Providencia alcalifaciens DSM 30120
9entr-d1nyt4 Providencia rustigianii DSM 4541 Carboxyl esterase Providencia rustigianii DSM 4541
9gamm-a0xyk4 Alteromonadales bacterium TW-7 probable hydrolase Alteromonadales bacterium TW-7
9gamm-a0ycy2 marine gamma proteobacterium HTCC2143 probable hydrolase (fragment) marine gamma proteobacterium HTCC2143
9gamm-a0z5e8 marine gamma proteobacterium HTCC2080 probable hydrolase marine gamma proteobacterium HTCC2080
9gamm-a4ada0 Congregibacter litoralis KT71 gamma proteobacterium NOR5-3 Carboxyl esterase, a\/b hydrolase Congregibacter litoralis KT71
9gamm-b5jtx2 gamma proteobacterium HTCC5015 Putative uncharacterized protein gamma proteobacterium HTCC5015
9gamm-b5jwt0 gamma proteobacterium HTCC5015 Hydrolase, alpha\/beta fold family gamma proteobacterium HTCC5015
9gamm-b5jx25 gamma proteobacterium HTCC5015 Hydrolase, alpha\/beta fold family protein gamma proteobacterium HTCC5015
9gamm-b8khd4 gamma proteobacterium NOR5-3 Putative uncharacterized protein gamma proteobacterium NOR5-3
9gamm-b8ksy0 gamma proteobacterium NOR51-B Putative uncharacterized protein gamma proteobacterium NOR51-B
9gamm-c8pvt7 Enhydrobacter aerosaccus SK60 Hydrolase, alpha\/beta fold family Enhydrobacter aerosaccus SK60
9gamm-c8pza4 Enhydrobacter aerosaccus SK60 Hydrolase, alpha\/beta fold family Enhydrobacter aerosaccus SK60
9gamm-q1ype7 marine gamma proteobacterium HTCC2207 probable hydrolase marine gamma proteobacterium HTCC2207
9gamm-q1yty4 marine gamma proteobacterium HTCC2207 probable hydrolase marine gamma proteobacterium HTCC2207
9mico-a3tjp7 Janibacter sp. HTCC2649 Probable hydrolase Janibacter sp. HTCC2649
9mico-a3trw6 Janibacter sp. HTCC2649 Carboxylesterase Janibacter sp. HTCC2649
9noca-c0stw9 Rhodococcus sp. HI-31 Putative hydrolase Rhodococcus sp. HI-31
9rhiz-c8sk39 Mesorhizobium opportunistum WSM2075 Alpha\/beta hydrolase fold protein Mesorhizobium opportunistum WSM2075
9rhob-a3tt13 Oceanicola batsensis HTCC2597 Probable hydrolase Oceanicola batsensis HTCC2597
9rhob-a3vhi4 Maritimibacter alkaliphilus HTCC2654 Putative hydrolase Maritimibacter alkaliphilus HTCC2654
9rhob-b5kex1 Octadecabacter antarcticus 238 Putative uncharacterized protein Octadecabacter antarcticus 238
9sphi-b5apj0 Sphingobacterium sp.\; Sphingobacterium faecium Putative streptothricin resistance protein\; macrolide esterase EstT Sphingobacterium sp. PM2-P1-29
9sphn-a3wh04 Erythrobacter sp. NAP1 Probable hydrolase Erythrobacter sp. NAP1
9sphn-a5p8z5 Erythrobacter sp. SD-21 Probable hydrolase Erythrobacter sp. SD-21
9sphn-q2n7c0 Erythrobacter litoralis HTCC2594 probable hydrolase Erythrobacter litoralis HTCC2594
9tryp-c6k3q7 Crithidia sp. ATCC 30255 Putative hydrolase-like protein Crithidia sp. ATCC 30255
9tryp-c6k3q8 Crithidia sp. ATCC 30255 Putative hydrolase-like protein Crithidia sp. ATCC 30255
9tryp-c6k3q9 Crithidia sp. ATCC 30255 Putative hydrolase-like protein Crithidia sp. ATCC 30255
accpu-c7rr72 Accumulibacter phosphatis (strain UW-1) Alpha\/beta hydrolase fold protein Accumulibacter phosphatis
accpu-c7rtu4 Accumulibacter phosphatis (strain UW-1) Alpha\/beta hydrolase fold protein Accumulibacter phosphatis
acic5-c1f7a9 Acidobacterium capsulatum (strain ATCC 51196 \/ DSM 11244 \/ JCM 7670) Hydrolase, alpha\/beta fold family Acidobacterium capsulatum
acica-d0s0a7 Acinetobacter calcoaceticus, Acinetobacter sp. , Acinetobacter baumannii, Acinetobacter junii Alpha\/beta hydrolase fold protein EstB Acinetobacter calcoaceticus
acica-estB Acinetobacter calcoaceticus DNA for EstB Acinetobacter calcoaceticus
acijo-d0sar0 Acinetobacter johnsonii SH046 Alpha\/beta hydrolase fold protein EstB Acinetobacter johnsonii SH046
acilw-d0sul3 Acinetobacter lwoffii SH145 Alpha\/beta hydrolase superfamily protein Acinetobacter lwoffii SH145
acira-c6rme7 Acinetobacter radioresistens (strains SK82\; SH164) Hydrolase, alpha\/beta fold family Acinetobacter radioresistens SK82
agrrk-b9j7k2 Agrobacterium radiobacter (strain K84 \/ ATCC BAA-868) Hydrolase protein Agrobacterium radiobacter
alcbs-q0vlq1 Alcanivorax borkumensis (strain SK2 \/ ATCC 700651 \/ DSM 11573) Alcanivorax sp. DG881, ABO2449 EH83 polyacetic acid hydrolase Alcanivorax borkumensis
alkmq-a6tql7 Alkaliphilus metalliredigens (strain QYMF) Alpha\/beta hydrolase fold Alkaliphilus metalliredigens
azovd-c1dqu3 Azotobacter vinelandii (strain DJ \/ ATCC BAA-1303\; AvOP) Alpha\/beta hydrolase fold protein Azotobacter vinelandii
bacah-a0rev7 Bacillus thuringiensis (strain Al Hakam) Bacillus cereus (strains NVH0597-99\; Rock3-42\; 03BB108\; BGSC 6E1\; 03BB102) carboxylesterase (EC 3.1.1.1) Bacillus thuringiensis
bacan-BA2738 Bacillus anthracis, Bacillus thuringiensis, Bacillus cereus, hydrolase, alpha\/beta fold family Bacillus anthracis
bacce-BC2743 Bacillus cereus, Bacillus thuringiensis carboxylesterase (EC 3.1.1.1) Bacillus cereus
bacce-c2xlh1 Bacillus cereus, Bacillus thuringiensis, Putative uncharacterized protein Bacillus cereus F65185
bacce-c2zq05 Bacillus cereus (AH1273\; AH1272\; AH603\; AH621\; BDRD-ST196) Bacillus mycoides DSM 2048 Bacillus weihenstephanensis (strain KBAB4) Putative uncharacterized protein Bacillus cereus
bacce-q736x9 Bacillus cereus (strains ATCC 10987\; G9241\; Q1\; m1293) hydrolase, alpha\/beta fold family Bacillus cereus
baccz-q63ak5 Bacillus cereus (strain ZK) carboxylesterase (EC 3.1.1.1) Bacillus cereus
bachk-q6hhz3 Bacillus thuringiensis, Bacillus cereus, Bacillus thuringiensis, carboxylesterase (EC 3.1.1.1) Bacillus thuringiensis
bacmy-c3aly3 Bacillus mycoides (strains Rock1-4 Rock3-17) Bacillus pseudomycoides DSM 12442 Putative uncharacterized protein Bacillus mycoides
bacti-q3f0c3 Bacillus thuringiensis serovar israelensis ATCC 35646, carboxylesterase (EC 3.1.1.1) Bacillus thuringiensis serovar israelensis ATCC 35646
beii9-b2iaz3 Beijerinckia indica subsp. indica (strain ATCC 9039 \/ DSM 1715 \/ NCI 8712) Alpha\/beta hydrolase fold Beijerinckia indica subsp. indica
beuc1-c5bvm8 Beutenbergia cavernae (strain ATCC BAA-8 \/ DSM 12333 \/ NBRC 16432) Alpha\/beta hydrolase fold protein Beutenbergia cavernae
braja-BLL2884 Bradyrhizobium japonicum bll2884 protein Bradyrhizobium japonicum
brasb-a5efp4 Bradyrhizobium sp. (strain BTAi1 \/ ATCC BAA-1182\; ORS278) Putative uncharacterized protein Bradyrhizobium sp.
braso-a4yr10 Bradyrhizobium sp. (strain ORS278) Putative uncharacterized protein Bradyrhizobium sp.
brebn-c0z8w7 Brevibacillus brevis (strain 47 \/ JCM 6285 \/ NBRC 100599) Putative uncharacterized protein Brevibacillus brevis
burs3-q39ns4 Burkholderia sp. (strain 383) Burkholderia cepacia strain ATCC 1776 alpha\/beta hydrolase (EC 1.11.1.10) Burkholderia sp.
catad-c7qat2 Catenulispora acidiphila (strain DSM 44928 \/ NRRL B-24433 \/ NBR 102108 \/ JCM 14897) Alpha\/beta hydrolase fold protein Catenulispora acidiphila
catad-c7qav4 Catenulispora acidiphila (strain DSM 44928 \/ NRRL B-24433 \/ NBR 102108 \/ JCM 14897) Alpha\/beta hydrolase fold protein Catenulispora acidiphila
causk-b0t2p6 Caulobacter sp. (strain K31) Alpha\/beta hydrolase fold Caulobacter sp.
causk-b0t721 Caulobacter sp. (strain K31) Alpha\/beta hydrolase fold Caulobacter sp.
cloac-CAP0097 Clostridium acetobutylicum carboxyl esterase, a\/b hydrolase Clostridium acetobutylicum
clob8-a6lyd7 Clostridium beijerinckii (strain ATCC 51743 \/ NCIMB 8052) (Clostridium acetobutylicum) Alpha\/beta hydrolase fold Clostridium beijerinckii
conwi-d3f461 Conexibacter woesei (strain DSM 14684 \/ JCM 11494 \/ NBRC 100937 \/ ID131577) Alpha\/beta hydrolase fold protein Conexibacter woesei
conwi-d3f719 Conexibacter woesei (strain DSM 14684 \/ JCM 11494 \/ NBRC 100937 \/ ID131577) Alpha\/beta hydrolase fold protein Conexibacter woesei
conwi-d3f8h2 Conexibacter woesei (strain DSM 14684 \/ JCM 11494 \/ NBRC 100937 \/ ID131577) Alpha\/beta hydrolase fold protein Conexibacter woesei
conwi-d3f9s1 Conexibacter woesei (strain DSM 14684 \/ JCM 11494 \/ NBRC 100937 \/ ID131577) Alpha\/beta hydrolase fold protein Conexibacter woesei
conwi-d3fd66 Conexibacter woesei (strain DSM 14684 \/ JCM 11494 \/ NBRC 100937 \/ ID131577) Alpha\/beta hydrolase fold protein Conexibacter woesei
decar-q47c05 Dechloromonas aromatica (strain RCB) alpha\/beta hydrolase fold Dechloromonas aromatica
desaa-b8fl18 Desulfatibacillum alkenivorans (strain AK-01) Alpha\/beta hydrolase fold protein Desulfatibacillum alkenivorans
desaa-b8flr5 Desulfatibacillum alkenivorans (strain AK-01) Alpha\/beta hydrolase fold protein Desulfatibacillum alkenivorans
ecoli-estX Escherichia coli sat streptothricin acetyl-transferase (on plasmid) (and strains SMS-3-5\/SECEC\; H489 ) Escherichia coli
ecoli-rdmC Escherichia coli macrolide 2'-phosphotransferase II, homlogue of strpu-rdmC possible C-C hydrolase Escherichia coli
erwct-q6d508 Erwinia carotovora (subsp. atroseptica) (Pectobacterium atrosepticum) Pectobacterium wasabiae (strain WPP163) probable hydrolase Erwinia carotovora
fraaa-q0rci1 Frankia alni (strain ACN14a) putative prolyl aminopeptidase Frankia alni
frasc-q2j632 Frankia sp. (strain CcI3) alpha\/beta hydrolase fold Frankia sp. CcI3
frasc-q2jb56 Frankia sp. (strain CcI3) alpha\/beta hydrolase fold Frankia sp. CcI3
frasn-a8l161 Frankia sp. (strain EAN1pec) Alpha\/beta hydrolase fold Frankia sp.
geoog-d2sh40 Geodermatophilus obscurus (strain ATCC 25078 \/ DSM 43160 \/ JCM 3152 \/ G-20) Alpha\/beta hydrolase fold protein Geodermatophilus obscurus
gluda-b5zhs5 Gluconacetobacter diazotrophicus (strain ATCC 49037 \/ DSM 5601 \/ PAl5) Alpha\/beta hydrolase fold Gluconacetobacter diazotrophicus
grabc-q0bsz9 Granulobacter bethesdensis (strain ATCC BAA-1260 \/ CGDNIH1) carboxylesterase (EC 3.1.1.1) Granulobacter bethesdensis
hahch-q2s803 Hahella chejuensis (strain KCTC 2396) AlphaBeta_hydrolase superfamily Hahella chejuensis
hahch-q2skv5 Hahella chejuensis (strain KCTC 2396)AlphaBeta_hydrolase superfamily) Hahella chejuensis
halo1-d0lx47 Haliangium ochraceum (strain DSM 14365 \/ JCM 11303 \/ SMP-2) Alpha\/beta hydrolase fold protein Haliangium ochraceum
herar-a4g4w8 Herminiimonas arsenicoxydans Putative alpha\/beta hydrolase Herminiimonas arsenicoxydans
hypna-q0bwt8 Hyphomonas neptunium (strain ATCC 15444) hydrolase, alpha\/beta fold family Hyphomonas neptunium
janma-a6sz66 Janthinobacterium sp. (strain Marseille) (Minibacterium massiliensis) Carboxyl esterase, a\/b hydrolase Janthinobacterium sp. Marseille
janma-a6szj6 Janthinobacterium sp. (strain Marseille) (Minibacterium massiliensis) Uncharacterized conserved protein Janthinobacterium sp. Marseille
klepn-c4pg07 Klebsiella pneumoniae Streptothricin acetyl-transferase Klebsiella pneumoniae
kocrd-b2ghy5 Kocuria rhizophila (strain ATCC 9341 \/ DSM 348 \/ NBRC 103217 \/ DC2201) Putative hydrolase Kocuria rhizophila
krifd-d2q3t3 Kribbella flavida (strain DSM 17836 \/ JCM 10339 \/ NBRC 14399) Alpha\/beta hydrolase fold protein Kribbella flavida
krifd-d2q445 Kribbella flavida (strain DSM 17836 \/ JCM 10339 \/ NBRC 14399) Alpha\/beta hydrolase fold protein Kribbella flavida
leibr-a4h956 Leishmania braziliensis\; Leishmania guyanensis Hydrolase, alpha\/beta fold family-like protein Leishmania braziliensis
leibr-a4h959 Leishmania braziliensis Hydrolase-like protein Leishmania braziliensis
leibr-a4h960 Leishmania braziliensis Hydrolase-like protein Leishmania braziliensis
leibr-a4hgl0 Leishmania braziliensis Putative hydrolase, alpha\/beta fold family Leishmania braziliensis
leiin-a4hxh8 Leishmania infantum Hydrolase, alpha\/beta fold family-like protein Leishmania infantum
leiin-a4hxi1 Leishmania infantum Hydrolase-like protein Leishmania infantum
leima-q4q8a8 Leishmania major Leishmania infantum hydrolase, alpha\/beta fold family, putative Leishmania major
leima-q4qe85 Leishmania major Leishmania infantum Leishmania braziliensis hydrolase-like protein (esterase-like protein) Leishmania major
leima-q4qe86 Leishmania major Leishmania infantum hydrolase-like protein (esterase-like protein) Leishmania major
leima-q4qe90 Leishmania major hydrolase, alpha\/beta fold family-like protein Leishmania major
meslo-mll3776 Mesorhizobium loti (Rhizobium loti) mll3776 streptothricin-acteyl-transferase Mesorhizobium loti
messb-q11g88 Mesorhizobium sp. (strain BNC1) alpha\/beta hydrolase fold Mesorhizobium sp.
metep-a9w0q4 Methylobacterium extorquens (strain PA1) Alpha\/beta hydrolase fold Methylobacterium extorquens
metrj-b1m0b7 Methylobacterium radiotolerans (strain ATCC 27329 \/ DSM 1819 \/ JC 2831) Alpha\/beta hydrolase fold Methylobacterium radiotolerans
myca9-b1mh71 Mycobacterium abscessus (strain ATCC 19977 \/ DSM 44196) Probable lipase\/esterase LipG Mycobacterium abscessus
myca9-b1mh73 Mycobacterium abscessus (strain ATCC 19977 \/ DSM 44196) Probable lipase\/esterase LipG Mycobacterium abscessus
mycgi-a4t1n2 Mycobacterium gilvum (strain PYR-GCK) (Mycobacterium flavescens (strain ATCC 700033 \/ PYR-GCK)) Alpha\/beta hydrolase fold protein Mycobacterium gilvum
mycle-lipG Mycobacterium leprae (strains TN\; Br4923) ML1899 lipG Mycobacterium leprae
mycpa-q73sf6 Mycobacterium paratuberculosis and Mycobacterium avium (strain 104) lipg Mycobacterium avium
mycs2-a0qs51 Mycobacterium smegmatis (strain ATCC 700084 \/ mc(2)155) hydrolase, alpha\/beta fold family protein BioH2 Mycobacterium smegmatis
mycsk-a1ubh7 Mycobacterium sp. (strain KMS and JLS and MCS) alpha\/beta hydrolase fold Mycobacterium sp.
myctu-lipG Mycobacterium tuberculosis, Mycobacterium bovis, Mycobacterium paratuberculosis, lipG RV0646C MT0674 BioH2 Mycobacterium tuberculosis
mycua-a0pm12 Mycobacterium ulcerans (strain Agy99) Mycobacterium marinum (strain ATCC BAA-535 \/ M) lipase\/esterase lipg1 Mycobacterium ulcerans
mycua-a0pm14 Mycobacterium ulcerans (strain Agy99) Mycobacterium marinum (strain ATCC BAA-535 \/ M) lipase\/esterase lipg2 Mycobacterium ulcerans
mycvp-a1t1b4 Mycobacterium vanbaalenii (strain DSM 7251 \/ PYR-1) alpha\/beta hydrolase fold Mycobacterium vanbaalenii
mycvp-a1t4h5 Mycobacterium vanbaalenii (strain DSM 7251 \/ PYR-1) alpha\/beta hydrolase fold Mycobacterium vanbaalenii
myxxd-q1d1c9 Myxococcus xanthus (strain DK 1622) esterase Myxococcus xanthus
myxxd-q1d2h8 Myxococcus xanthus (strain DK 1622) hydrolase, alpha\/beta fold family Myxococcus xanthus
nakmy-c8xfv3 Nakamurella multipartita (strain ATCC 700099 \/ DSM 44233 \/ JCM 9543 \/ Y-104) (Microsphaera multipartita) Alpha\/beta hydrolase fold protein Nakamurella multipartita
nech7-c7zdx8 Nectria haematococca (strain 77-13-4 \/ FGSC 9596 \/ MPVI) (Fusarium solani subsp. pisi) Putative uncharacterized protein Nectria haematococca
nocsj-a1sfj7 Nocardioides sp. (strain BAA-499 \/ JS614) alpha\/beta hydrolase fold Nocardioides sp.
novad-q2g848 Novosphingobium aromaticivorans (strain DSM 12444) alpha\/beta hydrolase Novosphingobium aromaticivorans
parl1-a7htr0 Parvibaculum lavamentivorans (strain DS-1 \/ DSM 13023 \/ NCIMB 13966) Alpha\/beta hydrolase fold Parvibaculum lavamentivorans
parl1-a7htr1 Parvibaculum lavamentivorans (strain DS-1 \/ DSM 13023 \/ NCIMB 13966) Alpha\/beta hydrolase fold Parvibaculum lavamentivorans
parl1-a7htr3 Parvibaculum lavamentivorans (strain DS-1 \/ DSM 13023 \/ NCIMB 13966) Alpha\/beta hydrolase fold Parvibaculum lavamentivorans
polna-a1vs35 Polaromonas naphthalenivorans (strain CJ2) alpha\/beta hydrolase fold Polaromonas naphthalenivorans
polsj-q126d1 Polaromonas sp. (strain JS666 \/ ATCC BAA-500) alpha\/beta hydrolase fold Polaromonas sp.
prore-d4btt4 Providencia rettgeri DSM 1131 Carboxyl esterase Providencia rettgeri DSM 1131
psea6-q15qh7 Pseudoalteromonas atlantica (strain T6c \/ BAA-1087) alpha\/beta hydrolase fold Pseudoalteromonas atlantica
pseae-PA3586 Pseudomonas aeruginosa (and strains UCBPP-PA14\; C3719\; LESB58\; 2192\; PA7) probable hydrolase Pseudomonas aeruginosa
pseae-Q9APW4 Pseudomonas aeruginosa hydrolase Pseudomonas aeruginosa
psee4-q1ie27 Pseudomonas entomophila (strain L48) putative hydrolase, alpha\/beta fold family Pseudomonas entomophila
psef5-q4k713 Pseudomonas fluorescens (strain Pf-5 \/ ATCC BAA-477) hydrolase, alpha\/beta fold family Pseudomonas fluorescens
psefs-c3k8y7 Pseudomonas fluorescens (strain SBW25) Putative exported hydrolase Pseudomonas fluorescens
psemy-a4xsy2 Pseudomonas mendocina (strain ymp) Alpha\/beta hydrolase fold protein Pseudomonas mendocina
psepf-q3k7h4 Pseudomonas fluorescens (strain PfO-1) alpha\/beta hydrolase fold precursor Pseudomonas fluorescens
psepu-PP1064 Pseudomonas putida (strains KT2440\; F1 \/ ATCC 700007\; GB-1) hydrolase, alpha\/beta fold family Pseudomonas putida
psepu-PP2804 Pseudomonas putida (strain KT2440) hydrolase, alpha\/beta fold family Pseudomonas putida
psepw-b1j4g1 Pseudomonas putida (strain W619) Alpha\/beta hydrolase fold Pseudomonas putida
psesy-PSPTO4178 Pseudomonas syringae (pv. tomato) hydrolase, alpha\/beta fold family Pseudomonas syringae
pseu2-q4zph7 Pseudomonas syringae pv. syringae (strain B728a) alpha\/beta hydrolase fold precursor Pseudomonas syringae pv. syringae
psyck-q1qbh3 Psychrobacter cryohalolentis, Psychrobacter arcticum, alpha\/beta hydrolase fold Psychrobacter cryohalolentis
psywf-a5wew0 Psychrobacter sp. (strain PRwf-1) Alpha\/beta hydrolase fold protein Psychrobacter sp.
psywf-a5wew1 Psychrobacter sp. (strain PRwf-1) Alpha\/beta hydrolase fold protein Psychrobacter sp.
ralp1-c6bnp5 Ralstonia pickettii (strain 12D) Alpha\/beta hydrolase fold protein Ralstonia pickettii
rhiec-q2k238 Rhizobium etli (strain CFN 42 \/ ATCC 51251\; CIAT 652) putative hydrolase protein Rhizobium etli
rhil3-q1m347 Rhizobium leguminosarum bv. viciae (strain 3841) putative streptothricin-acetyl-transferase Rhizobium leguminosarum bv. viciae
rhil3-q1mel6 Rhizobium leguminosarum bv. viciae (strain 3841) putative acetyltransferase Rhizobium leguminosarum bv. viciae
rhilw-b6a1y2 Rhizobium leguminosarum bv. trifolii (strains WSM2304\; WSM1325) Alpha\/beta hydrolase fold Rhizobium leguminosarum bv. trifolii
rhime-RA0724 Rhizobium meliloti (Sinorhizobium meliloti) putative hydrolase Sinorhizobium meliloti
rhisn-c3mdb6 Rhizobium sp. (strain NGR234) Putative hydrolase Rhizobium sp.
rhofd-q21vw5 Rhodoferax ferrireducens (strain DSM 15236 \/ ATCC BAA-621 \/ T118) alpha\/beta hydrolase Rhodoferax ferrireducens
rhopb-q218g8 Rhodopseudomonas palustris (strain BisB18) alpha\/beta hydrolase fold Rhodopseudomonas palustris
ricco-b9tm58 Ricinus communis (Castor bean) Valacyclovir hydrolase, putative Ricinus communis
sacen-a4ffy1 Saccharopolyspora erythraea (strain NRRL 23338) Hydrolase, alpha\/beta fold family Saccharopolyspora erythraea
salen-q75qq0 Salmonella enteritidis streptothricin acetyltransferase Salmonella enteritidis
salty-a1yjl0 Salmonella typhimurium, Salmonella choleraesuis, Salmonella enterica, Enterobacter cloacae, Proteus mirabilis Salmonella schwarzengrund, streptothricin acetyl-transferase Sat Salmonella typhimurium
serod-d1rs09 Serratia odorifera 4Rx13 Putative uncharacterized protein Serratia odorifera 4Rx13
serod-d4e633 Serratia odorifera DSM 4582 Carboxyl esterase Serratia odorifera DSM 4582
shiso-SAT Shigella sonnei Probable esterase\/lipase estX Shigella sonnei
silpo-q5lv17 Silicibacter pomeroyi hydrolase, alpha\/beta fold family Silicibacter pomeroyi
sinmw-a6ujk8 Sinorhizobium medicae (strain WSM419) (Ensifer medicae) Alpha\/beta hydrolase fold Sinorhizobium medicae
sphal-q1gqz1 Sphingopyxis alaskensis (Sphingomonas alaskensis) alpha\/beta hydrolase fold Sphingopyxis alaskensis
stanl-d3pv31 Stackebrandtia nassauensis (strain DSM 44728 \/ NRRL B-16338 \/ NBR 102104 \/ LLR-40K-21) Alpha\/beta hydrolase fold protein Stackebrandtia nassauensis
stanl-d3q2z9 Stackebrandtia nassauensis (strain DSM 44728 \/ NRRL B-16338 \/ NBR 102104 \/ LLR-40K-21) Alpha\/beta hydrolase fold protein Stackebrandtia nassauensis
stanl-d3q4i5 Stackebrandtia nassauensis (strain DSM 44728 \/ NRRL B-16338 \/ NBR 102104 \/ LLR-40K-21) Alpha\/beta hydrolase fold protein Stackebrandtia nassauensis
stanl-d3q721 Stackebrandtia nassauensis (strain DSM 44728 \/ NRRL B-16338 \/ NBR 102104 \/ LLR-40K-21) Alpha\/beta hydrolase fold protein Stackebrandtia nassauensis
stiau-q09c32 Stigmatella aurantiaca DW4\/3-1 10-carbomethoxy-13-deoxycarminomycin esterase Stigmatella aurantiaca DW4\/3-1
stiau-q09e73 Stigmatella aurantiaca DW4\/3-1 10-carbomethoxy-13-deoxycarminomycin esterase Stigmatella aurantiaca DW4\/3-1
stram-a3ki49 Streptomyces ambofaciens ATCC 23877 Putative hydrolase or acyltransferase Streptomyces ambofaciens ATCC 23877
strco-SCM1.11 Streptomyces coelicolor SCM1.11 Streptomyces coelicolor
strgg-b1w150 Streptomyces griseus subsp. griseus (strain JCM 4626 \/ NBRC 13350) Putative hydrolase Streptomyces griseus subsp. griseus
strgg-b1w2r7 Streptomyces griseus subsp. griseus (strain JCM 4626 \/ NBRC 13350) Putative hydrolase Streptomyces griseus subsp. griseus
strpe-dnrP Streptomyces peucetius 10-carbomethoxy-13-deoxycarminomycin esterase (dnrP) gene Streptomyces peucetius
strpu-rdmC Streptomyces purpurascens ATCC 25489 aclacinomycin methylesterase RdmC (rdmC) Streptomyces purpurascens
strrd-d2arp5 Streptosporangium roseum (strain ATCC 12428 \/ DSM 43021 \/ JCM 3005 \/ NI 9100) Alpha\/beta hydrolase fold protein Streptosporangium roseum
strrd-d2b0u2 Streptosporangium roseum (strain ATCC 12428 \/ DSM 43021 \/ JCM 3005 \/ NI 9100) Carboxylesterase Streptosporangium roseum
strrd-d2b9n9 Streptosporangium roseum (strain ATCC 12428 \/ DSM 43021 \/ JCM 3005 \/ NI 9100) Alpha\/beta hydrolase fold protein Streptosporangium roseum
strrd-d2bf33 Streptosporangium roseum (strain ATCC 12428 \/ DSM 43021 \/ JCM 3005 \/ NI 9100) Hydrolase protein Streptosporangium roseum
strsp-dauP Streptomyces sp. (dauP) Rhodomycin D methylesterase DauP Streptomyces sp.
strsw-c9yxp4 Streptomyces scabies (Streptomyces scabiei)\; Streptomyces acidiscabies Putative hydrolase Streptomyces scabies
strsw-c9z486 Streptomyces scabies (strain 87.22) (Streptomyces scabiei) Putative hydrolase Streptomyces scabies
strub-b3vbe7 Streptococcus uberis RdmC Streptococcus uberis
tryb2-q582c7 Trypanosoma brucei Trypanosoma brucei gambiense (strain MHOM\/CI\/86\/DAL972) hydrolase, alpha\/beta fold family, putative Trypanosoma brucei
tryb2-q582c8 Trypanosoma brucei Trypanosoma brucei gambiense (strain MHOM\/CI\/86\/DAL972) hydrolase, alpha\/beta fold family, putative Trypanosoma brucei
trycr-q4cq95 Trypanosoma cruzi hydrolase, alpha\/beta fold family, putative Trypanosoma cruzi
trycr-q4d8h9 Trypanosoma cruzi hydrolase, alpha\/beta fold family, putative Trypanosoma cruzi
trycr-q4d8i0 Trypanosoma cruzi hydrolase-like protein, putative Trypanosoma cruzi
uncba-Q9KIU0 uncultured bacterium esterase uncultured bacterium
varps-c5crm2 Variovorax paradoxus (strain S110) Alpha\/beta hydrolase fold protein Variovorax paradoxus
xenna-d3vf31 Xenorhabdus nematophila (strain ATCC 19061 \/ DSM 3370 \/ LMG 1036 \/ NCIB 9965 \/ AN6) Alpha\/beta hydrolase fold Xenorhabdus nematophila
yerbe-c4ryl6 Yersinia bercovieri ATCC 43970 Predicted hydrolase or acyltransferase (Alpha\/beta hydrolase superfamily) Yersinia bercovieri ATCC 43970
yeren-q29uc4 Yersinia enterocolitica streptothricin acetyl transferase Yersinia enterocolitica

Gene_locus_frgt Name Species
bacce-c2zrr8 Bacillus cereus (strains AH1273\; AH1272) Putative uncharacterized protein Bacillus cereus AH1273
strcl-b5gm73 Streptomyces clavuligerus ATCC 27064 10-carbomethoxy-13-deoxycarminomycin esterase Streptomyces clavuligerus ATCC 27064

Substrate Chemical Nomenclature Proteins
Aclacinomycin methyl (1R,2R,4S)-4-[(2R,4S,5S,6S)-4-(dimethylamino)-5-hydroxy-6-methyloxan-2-yl]oxy-2-ethyl-2,5,7-trihydroxy-6,11-dioxo-3,4-dihydro-1H-tetracene-1-carboxylate strpu-rdmC
Aclarubicin methyl (1R,2R,4S)-4-[(2R,4S,5S,6S)-4-(dimethylamino)-5-[(2S,4S,5S,6S)-4-hydroxy-6-methyl-5-[(2R,6S)-6-methyl-5-oxooxan-2-yl]oxyoxan-2-yl]oxy-6-methyloxan-2-yl]oxy-2-ethyl-2,5,7-trihydroxy-6,11-dioxo-3,4-dihydro-1H-tetracene-1-carboxylate strpu-rdmC
Leucomycin-a5 [(2S,3S,4R,6S)-6-[(2R,3S,4R,5R,6S)-6-[[(4R,5S,6S,7R,9R,10R,11E,13E,16R)-4,10-dihydroxy-5-methoxy-9,16-dimethyl-2-oxo-7-(2-oxoethyl)-1-oxacyclohexadeca-11,13-dien-6-yl]oxy]-4-(dimethylamino)-5-hydroxy-2-methyloxan-3-yl]oxy-4-hydroxy-2,4-dimethyloxan-3-yl] butanoate 9sphi-b5apj0    ecoli-estX
Polylactic-acid 2-Hydroxypropanoic acid homopolymer paeam-PLAA    thefu-q6a0i3    rhopa-q6n9m9    alcbs-q0vlq1    9zzzz-A0A0G3FEJ8    9acto-f7ix06    crysp-Q874E9    9bact-a4uz14    9bact-a4uz10    psea2-s6bc01    thefu-q6a0i4    aspng-g9m5r3    psecl-LIP1    psecl-LIP2    psecl-LIP3    9bact-a4uz12    9zzzz-a0a0g3fj39    bacpu-q6rsn0    fusso-cutas
Rhodomycin-D methyl (1R,2R,4S)-4-[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy-2-ethyl-2,5,7,12-tetrahydroxy-6,11-dioxo-3,4-dihydro-1H-tetracene-1-carboxylate strsp-dauP    strpe-dnrP
Tildipirosin (4R,5S,6S,7R,9R,11E,13E,15R,16R)-6-[(2R,3R,4S,5S,6R)-4-(dimethylamino)-3,5-dihydroxy-6-methyloxan-2-yl]oxy-16-ethyl-4-hydroxy-5,9,13-trimethyl-7-(2-piperidin-1-ylethyl)-15-(piperidin-1-ylmethyl)-1-oxacyclohexadeca-11,13-diene-2,10-dione 9sphi-b5apj0    ecoli-estX
Tilmicosin (4R,5S,6S,7R,9R,11E,13E,15R,16R)-6-[(2R,3R,4S,5S,6R)-4-(dimethylamino)-3,5-dihydroxy-6-methyloxan-2-yl]oxy-7-[2-[(3S,5R)-3,5-dimethylpiperidin-1-yl]ethyl]-16-ethyl-4-hydroxy-15-[[(2R,3R,4R,5R,6R)-5-hydroxy-3,4-dimethoxy-6-methyloxan-2-yl]oxymethyl]-5,9,13-trimethyl-1-oxacyclohexadeca-11,13-diene-2,10-dione 9sphi-b5apj0    ecoli-estX
Tylosin 2-[(4R,5S,6S,7R,9R,11E,13E,15R,16R)-6-[(2R,3R,4R,5S,6R)-5-[(2S,4R,5S,6S)-4,5-dihydroxy-4,6-dimethyloxan-2-yl]oxy-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-16-ethyl-4-hydroxy-15-[[(2R,3R,4R,5R,6R)-5-hydroxy-3,4-dimethoxy-6-methyloxan-2-yl]oxymethyl]-5,9,13-trimethyl-2,10-dioxo-1-oxacyclohexadeca-11,13-dien-7-yl]acetaldehyde 9sphi-b5apj0    ecoli-estX

Inhibitor Chemical Nomenclature Proteins
DCMAA (7S,9S)-7-[(2R,4S,5S,6S)-4-(dimethylamino)-5-[(4S,5R,6S)-4-hydroxy-6-methyl-5-[(2R,6R)-6-methyl-5-oxooxan-2-yl]oxyoxan-2-yl]oxy-6-methyloxan-2-yl]oxy-9-ethyl-4,6,9-trihydroxy-8,10-dihydro-7H-tetracene-5,12-dione strpu-rdmC
DCMAT (7S,9S)-7-[(2R,4S,5S,6S)-4-(dimethylamino)-5-hydroxy-6-methyloxan-2-yl]oxy-9-ethyl-4,6,9-trihydroxy-8,10-dihydro-7H-tetracene-5,12-dione strpu-rdmC

References (4)

Title : The global distribution of the macrolide esterase EstX from the alpha\/beta hydrolase superfamily - Lin_2024_Commun.Biol_7_781
Author(s) : Lin J , Lv H , Wang T , Tao H , Zhong Y , Zhou Y , Tang Y , Xie F , Zhuang G , Xu C , Chu Y , Wang X , Yang Y , Song T
Ref : Commun Biol , 7 :781 , 2024
Abstract :
PubMedSearch : Lin_2024_Commun.Biol_7_781
PubMedID: 38944651
Gene_locus related to this paper: ecoli-estX

Title : Biochemical and Structural Insights into Enzymatic Depolymerization of Polylactic Acid and Other Polyesters by Microbial Carboxylesterases - Hajighasemi_2016_Biomacromolecules_17_2027
Author(s) : Hajighasemi M , Nocek BP , Tchigvintsev A , Brown G , Flick R , Xu X , Cui H , Hai T , Joachimiak A , Golyshin PN , Savchenko A , Edwards EA , Yakunin AF
Ref : Biomacromolecules , 17 :2027 , 2016
Abstract :
PubMedSearch : Hajighasemi_2016_Biomacromolecules_17_2027
PubMedID: 27087107
Gene_locus related to this paper: marav-a1u5n0 , rhopa-q6n9m9 , alcbs-q0vlq1

Title : Crystal structure of aclacinomycin methylesterase with bound product analogues: implications for anthracycline recognition and mechanism - Jansson_2003_J.Biol.Chem_278_39006
Author(s) : Jansson A , Niemi J , Mantsala P , Schneider G
Ref : Journal of Biological Chemistry , 278 :39006 , 2003
Abstract :
PubMedSearch : Jansson_2003_J.Biol.Chem_278_39006
PubMedID: 12878604
Gene_locus related to this paper: ecoli-rdmC , strpu-rdmC

Title : Modifications of aclacinomycin T by aclacinomycin methyl esterase (RdmC) and aclacinomycin-10-hydroxylase (RdmB) from Streptomyces purpurascens - Wang_2000_Biochim.Biophys.Acta_1480_191
Author(s) : Wang Y , Niemi J , Airas K , Ylihonko K , Hakala J , Mantsala P
Ref : Biochimica & Biophysica Acta , 1480 :191 , 2000
Abstract :
PubMedSearch : Wang_2000_Biochim.Biophys.Acta_1480_191
PubMedID: 11004563