Aclacinomycin-methylesterase_RdmC

Relationship

Family: Aclacinomycin-methylesterase_RdmC

Block: X

Parent Family: No family

Comment

"PIRSF037216 Aclacinomycin methylesterase (RdmC) is one of the tailoring enzymes that modify the aklavinone skeleton in the biosynthesis of anthracyclines in Streptomyces species. alcbs-q0vlq1 EH83 is a polyacetic acid hydrolase"

Database

Interpro : IPR000073 Alpha\/beta hydrolase fold-1

PIRSF : PIRSF037216

Pdoc : No Pdoc

Pfam : PF12697 Abhydrolase_6

Prints : No Print

EC Number : 3.1.1.95

Sequences

Peptide in Fasta
Nucleotide in Fasta
Alignment with Multalin Text only
Seed alignment with MAFFT No colour
Alignment with MAFFT No colour
Dendrogram The dnd file

References (3)

Title : Biochemical and Structural Insights into Enzymatic Depolymerization of Polylactic Acid and Other Polyesters by Microbial Carboxylesterases - Hajighasemi_2016_Biomacromolecules_17_2027
Author(s) : Hajighasemi M , Nocek BP , Tchigvintsev A , Brown G , Flick R , Xu X , Cui H , Hai T , Joachimiak A , Golyshin PN , Savchenko A , Edwards EA , Yakunin AF
Ref : Biomacromolecules , 17 :2027 , 2016
Abstract : Hajighasemi_2016_Biomacromolecules_17_2027
ESTHER : Hajighasemi_2016_Biomacromolecules_17_2027
PubMedSearch : Hajighasemi_2016_Biomacromolecules_17_2027
PubMedID: 27087107
Gene_locus related to this paper: marav-a1u5n0 , rhopa-q6n9m9 , alcbs-q0vlq1

Title : Crystal structure of aclacinomycin methylesterase with bound product analogues: implications for anthracycline recognition and mechanism - Jansson_2003_J.Biol.Chem_278_39006
Author(s) : Jansson A , Niemi J , Mantsala P , Schneider G
Ref : Journal of Biological Chemistry , 278 :39006 , 2003
Abstract : Jansson_2003_J.Biol.Chem_278_39006
ESTHER : Jansson_2003_J.Biol.Chem_278_39006
PubMedSearch : Jansson_2003_J.Biol.Chem_278_39006
PubMedID: 12878604
Gene_locus related to this paper: ecoli-rdmC , strpu-rdmC

Title : Modifications of aclacinomycin T by aclacinomycin methyl esterase (RdmC) and aclacinomycin-10-hydroxylase (RdmB) from Streptomyces purpurascens - Wang_2000_Biochim.Biophys.Acta_1480_191
Author(s) : Wang Y , Niemi J , Airas K , Ylihonko K , Hakala J , Mantsala P
Ref : Biochimica & Biophysica Acta , 1480 :191 , 2000
Abstract : Wang_2000_Biochim.Biophys.Acta_1480_191
ESTHER : Wang_2000_Biochim.Biophys.Acta_1480_191
PubMedSearch : Wang_2000_Biochim.Biophys.Acta_1480_191
PubMedID: 11004563

Structures (2)

Genes Proteins in Aclacinomycin-methylesterase_RdmC family (213)

Fragments of genes in Aclacinomycin-methylesterase_RdmC family (2)

Structures in Aclacinomycin-methylesterase_RdmC family (2)

Substrates in Aclacinomycin-methylesterase_RdmC family (3)

Inhibitors in Aclacinomycin-methylesterase_RdmC family (2)