Gene_Locus Report

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Gene_locus Report for: malgo-a8qcw4

Malassezia globosa (strain ATCC MYA-4612 / CBS 7966) (Dandruff-associated fungus) Secretory lipase (Family LIP) MGL_4054 MgLIP2

Relationship
Family|Fungal-Bact_LIP
Block| X
Position in NCBI Life Tree|Malassezia globosa
(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.)
> cellular organisms: N E > Eukaryota: N E > Opisthokonta: N E > Fungi: N E > Dikarya: N E > Basidiomycota: N E > Ustilaginomycotina: N E > Malasseziomycetes: N E > Malasseziales: N E > Malasseziaceae: N E > Malassezia: N E > Malassezia globosa: N E


Molecular evidence
Database
No mutation
No structure
No kinetic





2 substrates: 1-Naphtylpalmitate, Paranitrophenyl-palmitate
No inhibitor
1 Genbank : AAYY01000018
1 UniProt : A8QCW4
1 UniProt : A8QCW4
1 Interpro : A8QCW4
1 Prodom : A8QCW4
1 Pfam : A8QCW4
1 PIRSF : A8QCW4
1 SUPERFAM : A8QCW4
Sequence
Graphical view for this peptide sequence: malgo-a8qcw4
Colored MSA for Fungal-Bact_LIP (raw)
MKLSLVVLTLISVAAQALALVARENLPKPQNDPFYQPPDGWESKKVGTIL
RSRKVNINTLVKDNLKEAWQLLYRTTYRSDDEPTTTVTTIMVPHNAQNDS
LVMFGDFEDAGAPQCAPSYTWRAGLTSDVSSIFNVGIAMLYLQEGYIVTM
PDKEGNKGAFGSGHVEGRQSLDGIRATLAFDKIGLNKNARVVGHGYSGGG
IQCGWTAALKKSYAPEINSVGWYTGGTPSNLTALVERINGGPFAGYVAGG
LGGVISTYPDVKAYTDKVFTKQAQKDLEFPQKHCQFEVVLRFPFKNFYDK
SFSTVGKRFLYEPVVQKALNELTMGTNPEFTPDTPVLMAHGISDEIAPYE
AAHKTYESWCKNGADVEFLSFVNPVSAHGVTTVTSSVPGFLWNRDRLQGK
PVQNGCREIKNHDAGINSNALGEDFESALGLLKGLLGDKIGPNDEYLKDA
LHK
Legend This sequence has been compared to family alignement (MSA)
red => minority aminoacid
blue => majority aminoacid
color intensity => conservation rate
title => sequence position(MSA position)aminoacid rate
Catalytic site
Catalytic site in the MSA

MKLSLVVLTLISVAAQALALVARENLPKPQNDPFYQPPDGWESKKVGTIL
RSRKVNINTLVKDNLKEAWQLLYRTTYRSDDEPTTTVTTIMVPHNAQNDS
LVMFGDFEDAGAPQCAPSYTWRAGLTSDVSSIFNVGIAMLYLQEGYIVTM
PDKEGNKGAFGSGHVEGRQSLDGIRATLAFDKIGLNKNARVVGHGYSGGG
IQCGWTAALKKSYAPEINSVGWYTGGTPSNLTALVERINGGPFAGYVAGG
LGGVISTYPDVKAYTDKVFTKQAQKDLEFPQKHCQFEVVLRFPFKNFYDK
SFSTVGKRFLYEPVVQKALNELTMGTNPEFTPDTPVLMAHGISDEIAPYE
AAHKTYESWCKNGADVEFLSFVNPVSAHGVTTVTSSVPGFLWNRDRLQGK
PVQNGCREIKNHDAGINSNALGEDFESALGLLKGLLGDKIGPNDEYLKDA
LHK


References
    Title: Purification and characterization of a secretory lipolytic enzyme, MgLIP2, from Malassezia globosa
    Juntachai W, Oura T, Kajiwara S
    Ref: Microbiology (Reading), 157:3492, 2011 : PubMed

            

    Title: Dandruff-associated Malassezia genomes reveal convergent and divergent virulence traits shared with plant and human fungal pathogens
    Xu J, Saunders CW, Hu P, Grant RA, Boekhout T, Kuramae EE, Kronstad JW, Deangelis YM, Reeder NL and Dawson TL, Jr. <11 more author(s)>
    Ref: Proc Natl Acad Sci U S A, 104:18730, 2007 : PubMed

            


Other Papers


Send your questions or comments to :
Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
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